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","ogTitle":"","ogDescription":"","ogImgId":"","twTitle":"","twDescription":"","twImgId":""},"disqusIdentifier":"74092 http://science.kqed.org/quest/?p=74092","disqusUrl":"https://ww2.kqed.org/quest/2015/05/14/career-spotlight-developmental-and-stem-cell-biology-graduate-student/","disqusTitle":"Career Spotlight: Developmental and Stem Cell Biology Graduate Student","videoEmbed":"http://www.youtube.com/watch?v=g8a6jFrc7F4","source":"Biology","sourceUrl":"https://ww2.kqed.org/quest/category/biology/","path":"/quest/74092/career-spotlight-developmental-and-stem-cell-biology-graduate-student","audioTrackLength":null,"parsedContent":[{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003cp>\u003cem>Trouble viewing the video? Stream or download it on \u003ca href=\"http://www.pbslearningmedia.org/resource/c7e42f18-46b1-4cb8-8588-1c628a3e5b18/developmental-stem-cell-biology-graduate-student/\"> PBS LearningMedia\u003c/a>.\u003c/em>\u003cbr>\n \u003cbr>\nElijah Martin is a second-year graduate student in the \u003ca href=\"https://dscb.ucsf.edu/\">Developmental and Stem Cell Biology \u003c/a>program at University of California, San Francisco. He works in the laboratory of \u003ca href=\"http://gladstoneinstitutes.org/u/dsrivastava/SrivastavaLab.htm\">Dr. Deepak Srivastava \u003c/a>at the Gladstone Institutes. Martin studies how the heart forms to try to understand the causes of heart disease in order to develop therapies. In the lab, he grows heart cells in petri dishes, which involves mixing together different chemicals and nutrients to get the cells to grow and develop into a heart. He uses microscopes to track the growth of the cells. Since he was a young child, Martin has wanted to study the heart and he says attending graduate school will help turn his dream into a career.\u003c/p>\n\u003cp>This video is featured in our \u003cb>\u003ca href=\"http://foldscope.woop.ie/\" target=\"_blank\">Engineering Is: Diagnosing Diseases with Origami Microscopes\u003c/a>\u003c/b>e-book. You can find our other e-books at \u003ca href=\"http://blogs.kqed.org/education/e-books/\">kqed.org/ebooks\u003c/a>.\u003c/p>\n\u003cp>\u003c/p>\u003c/div>","attributes":{"named":{},"numeric":[]}},{"type":"component","content":"","name":"ad","attributes":{"named":{"label":"fullwidth"},"numeric":["fullwidth"]}},{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003c/p>\u003cp>\u003c/p>\n\u003c/div>\u003c/p>","attributes":{"named":{},"numeric":[]}}],"link":"/quest/74092/career-spotlight-developmental-and-stem-cell-biology-graduate-student","authors":["6544"],"series":["quest_13374"],"categories":["quest_4","quest_12"],"tags":["quest_13128","quest_793","quest_12946","quest_13173","quest_12269","quest_1218","quest_13172","quest_1331","quest_1332","quest_3351","quest_2349","quest_2791","quest_3025","quest_3071"],"collections":["quest_13175"],"featImg":"quest_74094","label":"source_quest_74092"},"quest_42114":{"type":"posts","id":"quest_42114","meta":{"index":"posts_1591205157","site":"quest","id":"42114","score":null,"sort":[1344265241000]},"guestAuthors":[],"slug":"newly-discovered-stem-cells-cause-clogged-arteries","title":"Newly Discovered Stem Cells Cause Clogged Arteries","publishDate":1344265241,"format":"standard","headTitle":"QUEST | KQED Science","labelTerm":{"site":"quest"},"content":"\u003cfigure id=\"attachment_42120\" class=\"wp-caption alignnone\" style=\"max-width: 640px\">\u003ca href=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2012/08/stemcell-researchers640x360.jpg\">\u003cimg src=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2012/08/stemcell-researchers640x360.jpg\" alt=\"UCB researchers exam vascular stem cells in the microscope\" title=\"stemcell-researchers640x360\" width=\"640\" height=\"360\" class=\"size-full wp-image-42120\" srcset=\"https://ww2.kqed.org/app/uploads/sites/39/2012/08/stemcell-researchers640x360.jpg 640w, https://ww2.kqed.org/app/uploads/sites/39/2012/08/stemcell-researchers640x360-400x225.jpg 400w\" sizes=\"(max-width: 640px) 100vw, 640px\">\u003c/a>\u003cfigcaption class=\"wp-caption-text\">Zhenyu Tang (seated at microscope) examines vascular stem cells in culture along with Aijun Wang (left) and Song Li (right). (Zoey Huang photo.)\u003c/figcaption>\u003c/figure>\n\u003cp>Odds are that you know someone who’s had a heart attack. One American suffers a coronary event \u003ca href=\"http://circ.ahajournals.org/content/125/1/e2.full.pdf\" title=\"prevalence of atherosclerosis\">every 25 seconds and about every minute\u003c/a> someone dies from one. \u003c/p>\n\u003cp>Doctors thought they understood artery-hardening diseases, such as \u003ca href=\"http://www.nhlbi.nih.gov/health/health-topics/topics/atherosclerosis/\" title=\"about atherosclerosis\">atherosclerosis\u003c/a>, that lead to heart attacks, strokes and death. But these generally accepted theories are contradicted by new research performed at the University of California, Berkeley. According to a \u003ca href=\"http://www.nature.com/ncomms/journal/v3/n6/full/ncomms1867.html\" title=\"Song Li journal article in Nature Communications\">new study\u003c/a> published in \u003cem>Nature Communications\u003c/em>, a previously unknown type of stem cell is actually the underlying cause for clogged arteries.\u003c/p>\n\u003cp>For decades, scientists believed that heart disease was caused by the smooth muscle cells that line artery walls. It was thought that bad (LDL) cholesterol damaged the arteries and triggered smooth muscle cells to rapidly reproduce. This led to a build up of fibrous scar tissue that narrowed and hardened the arteries, restricting blood flow. As a result, most therapies focus on physically widening the inside of the blood vessels or replacing the damaged area with a graft.\u003c/p>\n\u003cp>These beliefs are challenged by new research performed by principle investigator Song Li, a professor of bioengineering and researcher at the Berkeley Stem Cell Center, and his colleagues.\u003c/p>\n\u003cp>“For the first time, we are showing evidence that vascular diseases are actually a kind of stem cell disease,” said Song Li in a university news release. “This work should revolutionize therapies for vascular diseases because we now know that stem cells rather than smooth muscle cells are the correct therapeutic target.”\u003c/p>\n\u003cp>[ad fullwidth]\u003c/p>\n\u003cp>Analyzing cells from arteries and veins of transgenic mice, the researchers were able to trace the lineage of the cells that rapidly reproduced in the vessel walls to prove that they were not smooth muscle cells as current theory predicted. Further experiments discovered that they are actually multipotent vascular stem cells, meaning that they can become various specialized cells – smooth muscle, nerve, cartilage, bone and fat cells. The same type of stem cells were also identified in human blood vessels.\u003c/p>\n\u003cp>This explains why previous studies mistook the multipotent vascular stem cells as smooth muscle cells. It also explains how a soft artery can calcify and harden, since the multipotent stem cells can also form bone and cartilage.\u003c/p>\n\u003cfigure id=\"attachment_42124\" class=\"wp-caption alignleft\" style=\"max-width: 319px\">\u003ca href=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2012/08/stemcell-schematic350.jpg\">\u003cimg src=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2012/08/stemcell-schematic350-319x253.jpg\" alt=\"Within walls of blood vessels are smooth muscle cells and newly discovered vascular stem cells. The stem cells are able to differentiate into smooth muscle cells, fat, cartilage and bone cells. UC Berkeley researchers provide evidence that these stem cells are contributing to clogged and hardened arteries.\" title=\"stemcell-schematic350\" width=\"319\" height=\"253\" class=\"size-medium wp-image-42124\">\u003c/a>\u003cfigcaption class=\"wp-caption-text\">Within the walls of blood vessels are smooth muscle cells and newly discovered vascular stem cells. The stem cells are able to differentiate into smooth muscle, fat, cartilage and bone cells. UC Berkeley researchers provide evidence that these stem cells are contributing to clogged and hardened arteries. (Song Li illustration)\u003c/figcaption>\u003c/figure>\n\u003cp>When new research dramatically challenges existing scientific beliefs, often people resist the new ideas. Dr. Jill Helms, a professor in the Department of Surgery at Stanford School of Medicine and co-author of the study, explained in an \u003ca href=\"http://www.npr.org/2012/06/08/154587990/identifying-the-real-culprit-behind-killer-vascular-diseases\" title=\"Jill Helms NPR Science Friday interview\">NPR interview\u003c/a>, “There is resistance oftentimes, but there can be moments where there’s great clarity and I think Song’s work certainly falls within that category.”\u003c/p>\n\u003cp>\u003c/p>\n\u003cp>However, the research still needs to be repeated by other research groups, as well as verified in other animals and humans. Song Li’s collaboration is already studying human cells from healthy and diseased arteries. They are also developing techniques to rapidly screen drugs that specifically target these stem cells without affecting the normal (endothelial) cells that line a blood vessel, which could ultimately lead to new therapies.\u003c/p>\n\n","blocks":[],"excerpt":"Scientists thought they understood how arteries hardened and clogged, but they may have been wrong. New research indicates that a previously unknown type of stem cell is actually the underlying cause of clogged arteries. If confirmed, it could lead to new therapies.","status":"publish","parent":0,"modified":1346781910,"stats":{"hasAudio":false,"hasVideo":false,"hasChartOrMap":false,"iframeSrcs":[],"hasGoogleForm":false,"hasGallery":false,"hasHearkenModule":false,"hasPolis":false,"paragraphCount":11,"wordCount":582},"headData":{"title":"Newly Discovered Stem Cells Cause Clogged Arteries | KQED","description":"Scientists thought they understood how arteries hardened and clogged, but they may have been wrong. New research indicates that a previously unknown type of stem cell is actually the underlying cause of clogged arteries. If confirmed, it could lead to new therapies.","ogTitle":"","ogDescription":"","ogImgId":"","twTitle":"","twDescription":"","twImgId":""},"disqusIdentifier":"42114 http://science.kqed.org/quest/?p=42114","disqusUrl":"https://ww2.kqed.org/quest/2012/08/06/newly-discovered-stem-cells-cause-clogged-arteries/","disqusTitle":"Newly Discovered Stem Cells Cause Clogged Arteries","path":"/quest/42114/newly-discovered-stem-cells-cause-clogged-arteries","audioTrackLength":null,"parsedContent":[{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003cfigure id=\"attachment_42120\" class=\"wp-caption alignnone\" style=\"max-width: 640px\">\u003ca href=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2012/08/stemcell-researchers640x360.jpg\">\u003cimg src=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2012/08/stemcell-researchers640x360.jpg\" alt=\"UCB researchers exam vascular stem cells in the microscope\" title=\"stemcell-researchers640x360\" width=\"640\" height=\"360\" class=\"size-full wp-image-42120\" srcset=\"https://ww2.kqed.org/app/uploads/sites/39/2012/08/stemcell-researchers640x360.jpg 640w, https://ww2.kqed.org/app/uploads/sites/39/2012/08/stemcell-researchers640x360-400x225.jpg 400w\" sizes=\"(max-width: 640px) 100vw, 640px\">\u003c/a>\u003cfigcaption class=\"wp-caption-text\">Zhenyu Tang (seated at microscope) examines vascular stem cells in culture along with Aijun Wang (left) and Song Li (right). (Zoey Huang photo.)\u003c/figcaption>\u003c/figure>\n\u003cp>Odds are that you know someone who’s had a heart attack. One American suffers a coronary event \u003ca href=\"http://circ.ahajournals.org/content/125/1/e2.full.pdf\" title=\"prevalence of atherosclerosis\">every 25 seconds and about every minute\u003c/a> someone dies from one. \u003c/p>\n\u003cp>Doctors thought they understood artery-hardening diseases, such as \u003ca href=\"http://www.nhlbi.nih.gov/health/health-topics/topics/atherosclerosis/\" title=\"about atherosclerosis\">atherosclerosis\u003c/a>, that lead to heart attacks, strokes and death. But these generally accepted theories are contradicted by new research performed at the University of California, Berkeley. According to a \u003ca href=\"http://www.nature.com/ncomms/journal/v3/n6/full/ncomms1867.html\" title=\"Song Li journal article in Nature Communications\">new study\u003c/a> published in \u003cem>Nature Communications\u003c/em>, a previously unknown type of stem cell is actually the underlying cause for clogged arteries.\u003c/p>\n\u003cp>For decades, scientists believed that heart disease was caused by the smooth muscle cells that line artery walls. It was thought that bad (LDL) cholesterol damaged the arteries and triggered smooth muscle cells to rapidly reproduce. This led to a build up of fibrous scar tissue that narrowed and hardened the arteries, restricting blood flow. As a result, most therapies focus on physically widening the inside of the blood vessels or replacing the damaged area with a graft.\u003c/p>\n\u003cp>These beliefs are challenged by new research performed by principle investigator Song Li, a professor of bioengineering and researcher at the Berkeley Stem Cell Center, and his colleagues.\u003c/p>\n\u003cp>“For the first time, we are showing evidence that vascular diseases are actually a kind of stem cell disease,” said Song Li in a university news release. “This work should revolutionize therapies for vascular diseases because we now know that stem cells rather than smooth muscle cells are the correct therapeutic target.”\u003c/p>\n\u003cp>\u003c/p>\u003c/div>","attributes":{"named":{},"numeric":[]}},{"type":"component","content":"","name":"ad","attributes":{"named":{"label":"fullwidth"},"numeric":["fullwidth"]}},{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003c/p>\n\u003cp>Analyzing cells from arteries and veins of transgenic mice, the researchers were able to trace the lineage of the cells that rapidly reproduced in the vessel walls to prove that they were not smooth muscle cells as current theory predicted. Further experiments discovered that they are actually multipotent vascular stem cells, meaning that they can become various specialized cells – smooth muscle, nerve, cartilage, bone and fat cells. The same type of stem cells were also identified in human blood vessels.\u003c/p>\n\u003cp>This explains why previous studies mistook the multipotent vascular stem cells as smooth muscle cells. It also explains how a soft artery can calcify and harden, since the multipotent stem cells can also form bone and cartilage.\u003c/p>\n\u003cfigure id=\"attachment_42124\" class=\"wp-caption alignleft\" style=\"max-width: 319px\">\u003ca href=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2012/08/stemcell-schematic350.jpg\">\u003cimg src=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2012/08/stemcell-schematic350-319x253.jpg\" alt=\"Within walls of blood vessels are smooth muscle cells and newly discovered vascular stem cells. The stem cells are able to differentiate into smooth muscle cells, fat, cartilage and bone cells. UC Berkeley researchers provide evidence that these stem cells are contributing to clogged and hardened arteries.\" title=\"stemcell-schematic350\" width=\"319\" height=\"253\" class=\"size-medium wp-image-42124\">\u003c/a>\u003cfigcaption class=\"wp-caption-text\">Within the walls of blood vessels are smooth muscle cells and newly discovered vascular stem cells. The stem cells are able to differentiate into smooth muscle, fat, cartilage and bone cells. UC Berkeley researchers provide evidence that these stem cells are contributing to clogged and hardened arteries. (Song Li illustration)\u003c/figcaption>\u003c/figure>\n\u003cp>When new research dramatically challenges existing scientific beliefs, often people resist the new ideas. Dr. Jill Helms, a professor in the Department of Surgery at Stanford School of Medicine and co-author of the study, explained in an \u003ca href=\"http://www.npr.org/2012/06/08/154587990/identifying-the-real-culprit-behind-killer-vascular-diseases\" title=\"Jill Helms NPR Science Friday interview\">NPR interview\u003c/a>, “There is resistance oftentimes, but there can be moments where there’s great clarity and I think Song’s work certainly falls within that category.”\u003c/p>\n\u003cp>\u003c/p>\n\u003cp>However, the research still needs to be repeated by other research groups, as well as verified in other animals and humans. Song Li’s collaboration is already studying human cells from healthy and diseased arteries. They are also developing techniques to rapidly screen drugs that specifically target these stem cells without affecting the normal (endothelial) cells that line a blood vessel, which could ultimately lead to new therapies.\u003c/p>\n\n\u003c/div>\u003c/p>","attributes":{"named":{},"numeric":[]}}],"link":"/quest/42114/newly-discovered-stem-cells-cause-clogged-arteries","authors":["6360"],"categories":["quest_4","quest_12"],"tags":["quest_3467","quest_11334","quest_10997","quest_13202","quest_2791","quest_10452"],"featImg":"quest_42120","label":"quest"},"quest_26499":{"type":"posts","id":"quest_26499","meta":{"index":"posts_1591205157","site":"quest","id":"26499","score":null,"sort":[1319831433000]},"guestAuthors":[],"slug":"food-increases-gut-size-by-stimulating-stem-cells-and-insulin","title":"Food Increases Gut Size By Stimulating Stem Cells And Insulin ","publishDate":1319831433,"format":"standard","headTitle":"QUEST | KQED Science","labelTerm":{"site":"quest"},"content":"\u003cp>\u003ca href=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2011/10/fruit-fly.jpg\">\u003cimg src=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2011/10/fruit-fly-300x169.jpg\" alt=\"\" title=\"fruit fly\" width=\"300\" height=\"169\" class=\"size-thumbnail wp-image-26504\">\u003c/a>\u003c/p>\n\u003cp>New research from UC Berkeley sheds light on how our bodies respond to food, making room for more when it is available and shrinking the gut when food is scarce.\u003c/p>\n\u003cp>Researchers investigated how stem cells in the gut of the fruit fly respond when different amounts of food are present. They found that when food is abundant, stem cells in the gut divide more rapidly, increasing the size of the gut as long as food continues to be available. When food is removed, the cells stop dividing and the gut shrinks down again.\u003c/p>\n\u003cp>“The real surprise was that the fruit fly intestine is capable of secreting its own insulin,” said principle investigator David Bilder in a \u003ca href=\"http://www.universityofcalifornia.edu/news/article/26562\">press release\u003c/a>. “This intestinal insulin spikes immediately after feeding and talks directly to stem cells, so the intestine controls its own adaptation.”\u003c/p>\n\u003cp>Insulin is also the primary signaling molecule for converting blood sugar into usable energy in muscles, and storing it as fat.\u003c/p>\n\u003cp>[ad fullwidth]\u003c/p>\n\u003cp>\u003c/p>\n\u003cp>What the current findings mean for human physiology or chronic overeating is still unknown, but it raises many new questions regarding the role of intestinal stem cells and metabolism.\u003c/p>\n\n","blocks":[],"excerpt":"Stem cells in the gut of Drosophila divide in response to food.","status":"publish","parent":0,"modified":1319831433,"stats":{"hasAudio":false,"hasVideo":false,"hasChartOrMap":false,"iframeSrcs":[],"hasGoogleForm":false,"hasGallery":false,"hasHearkenModule":false,"hasPolis":false,"paragraphCount":8,"wordCount":194},"headData":{"title":"Food Increases Gut Size By Stimulating Stem Cells And Insulin | KQED","description":"Stem cells in the gut of Drosophila divide in response to food.","ogTitle":"","ogDescription":"","ogImgId":"","twTitle":"","twDescription":"","twImgId":""},"disqusIdentifier":"26499 http://science.kqed.org/quest/?p=26499","disqusUrl":"https://ww2.kqed.org/quest/2011/10/28/food-increases-gut-size-by-stimulating-stem-cells-and-insulin/","disqusTitle":"Food Increases Gut Size By Stimulating Stem Cells And Insulin ","path":"/quest/26499/food-increases-gut-size-by-stimulating-stem-cells-and-insulin","audioTrackLength":null,"parsedContent":[{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003cp>\u003ca href=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2011/10/fruit-fly.jpg\">\u003cimg src=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2011/10/fruit-fly-300x169.jpg\" alt=\"\" title=\"fruit fly\" width=\"300\" height=\"169\" class=\"size-thumbnail wp-image-26504\">\u003c/a>\u003c/p>\n\u003cp>New research from UC Berkeley sheds light on how our bodies respond to food, making room for more when it is available and shrinking the gut when food is scarce.\u003c/p>\n\u003cp>Researchers investigated how stem cells in the gut of the fruit fly respond when different amounts of food are present. They found that when food is abundant, stem cells in the gut divide more rapidly, increasing the size of the gut as long as food continues to be available. When food is removed, the cells stop dividing and the gut shrinks down again.\u003c/p>\n\u003cp>“The real surprise was that the fruit fly intestine is capable of secreting its own insulin,” said principle investigator David Bilder in a \u003ca href=\"http://www.universityofcalifornia.edu/news/article/26562\">press release\u003c/a>. “This intestinal insulin spikes immediately after feeding and talks directly to stem cells, so the intestine controls its own adaptation.”\u003c/p>\n\u003cp>Insulin is also the primary signaling molecule for converting blood sugar into usable energy in muscles, and storing it as fat.\u003c/p>\n\u003cp>\u003c/p>\u003c/div>","attributes":{"named":{},"numeric":[]}},{"type":"component","content":"","name":"ad","attributes":{"named":{"label":"fullwidth"},"numeric":["fullwidth"]}},{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003c/p>\n\u003cp>\u003c/p>\n\u003cp>What the current findings mean for human physiology or chronic overeating is still unknown, but it raises many new questions regarding the role of intestinal stem cells and metabolism.\u003c/p>\n\n\u003c/div>\u003c/p>","attributes":{"named":{},"numeric":[]}}],"link":"/quest/26499/food-increases-gut-size-by-stimulating-stem-cells-and-insulin","authors":["10218"],"categories":["quest_4"],"tags":["quest_1122","quest_13201","quest_3966","quest_13202","quest_2791","quest_3021"],"label":"quest"},"quest_16996":{"type":"posts","id":"quest_16996","meta":{"index":"posts_1591205157","site":"quest","id":"16996","score":null,"sort":[1245370560000]},"guestAuthors":[],"slug":"stem-cells-and-horses","title":"Stem Cells and Horses","publishDate":1245370560,"format":"audio","headTitle":"QUEST | KQED Science","labelTerm":{"site":"quest"},"content":"\u003cp>http://www.kqed.org/.stream/anon/radio/quest/2009/06/2009-06-22-quest.mp3\u003c/p>\n\u003cp>At UC Davis Veterinary Hospital, competitive performance horses receive stem cell treatments that are still off limits to humans. Veterinarians say their success may pave the way for other animals... like us.\u003c/p>\n\u003cp>[ad fullwidth]\u003c/p>\u003cp>\u003c/p>\n","blocks":[],"excerpt":"At UC Davis Veterinary Hospital, competitive performance horses receive stem cell treatments that are still off limits to humans. Veterinarians say their success may pave the way for other animals... like us.","status":"publish","parent":0,"modified":1337710268,"stats":{"hasAudio":true,"hasVideo":false,"hasChartOrMap":false,"iframeSrcs":[],"hasGoogleForm":false,"hasGallery":false,"hasHearkenModule":false,"hasPolis":false,"paragraphCount":3,"wordCount":49},"headData":{"title":"Stem Cells and Horses | KQED","description":"At UC Davis Veterinary Hospital, competitive performance horses receive stem cell treatments that are still off limits to humans. Veterinarians say their success may pave the way for other animals... like us.","ogTitle":"","ogDescription":"","ogImgId":"","twTitle":"","twDescription":"","twImgId":""},"disqusIdentifier":"16996 http://science.kqed.org/quest/audio/stem-cells-and-horses/","disqusUrl":"https://ww2.kqed.org/quest/2009/06/18/stem-cells-and-horses/","disqusTitle":"Stem Cells and Horses","path":"/quest/16996/stem-cells-and-horses","audioUrl":"http://www.kqed.org/.stream/anon/radio/quest/2009/06/2009-06-22-quest.mp3","audioDuration":null,"audioTrackLength":null,"parsedContent":[{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003cp>http://www.kqed.org/.stream/anon/radio/quest/2009/06/2009-06-22-quest.mp3\u003c/p>\n\u003cp>At UC Davis Veterinary Hospital, competitive performance horses receive stem cell treatments that are still off limits to humans. Veterinarians say their success may pave the way for other animals... like us.\u003c/p>\n\u003cp>\u003c/p>\u003c/div>","attributes":{"named":{},"numeric":[]}},{"type":"component","content":"","name":"ad","attributes":{"named":{"label":"fullwidth"},"numeric":["fullwidth"]}},{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003c/p>\u003cp>\u003c/p>\n\u003c/div>\u003c/p>","attributes":{"named":{},"numeric":[]}}],"link":"/quest/16996/stem-cells-and-horses","authors":["10216"],"categories":["quest_4","quest_5","quest_12"],"tags":["quest_252","quest_13201","quest_10968","quest_3351","quest_1783","quest_2349","quest_13202","quest_2791","quest_2990","quest_3022","quest_10519"],"label":"quest"},"quest_1693":{"type":"posts","id":"quest_1693","meta":{"index":"posts_1591205157","site":"quest","id":"1693","score":null,"sort":[1237225277000]},"guestAuthors":[],"slug":"why-human-cloning-shouldnt-be-a-big-worry","title":"Why Human Cloning Shouldn't be a Big Worry","publishDate":1237225277,"format":"standard","headTitle":"QUEST | KQED Science","labelTerm":{"site":"quest"},"content":"\u003cp>\u003cspan class=\"left\">\u003cimg src=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2009/03/twins.jpg\" alt=\"\">\u003cem>Identical twins are more similar to one another than a clone\u003cbr>\nwill be to the person cloned.\u003c/em>\u003c/span>President Obama lifted the ban on federal funding of embryonic stem cell research last Monday. Many researchers breathed a sigh of relief as they could finally get to work using these cells to find treatments and even cures for many debilitating diseases and injuries.\u003c/p>\n\u003cp>Of course, these cells aren't any less controversial than they were eight years ago. Researchers will still need to destroy embryos to get these cells (at least until they perfect \u003ca href=\"http://www.thetech.org/genetics/news.php?id=107\">iPS cells\u003c/a> which would make this part of the debate moot). Anyone who considers an embryo made up of a few hundred cells to be alive will protest that embryo's destruction.\u003c/p>\n\u003cp>This is a legitimate argument based on when someone believes life begins. But some protests I heard were from people worried about embryonic stem cells being used to clone humans. What I can't figure out is why anyone would want to clone someone.\u003c/p>\n\u003cp>Cloning won't be like it is in the movies. Scientists won't take a cell from someone and make an exact copy of a person who is the same age and has the same memory.\u003c/p>\n\u003cp>Instead, a human will be cloned like any other mammal. First they'll remove the DNA-containing nucleus from an egg. Then they'll fuse that egg with a cell from the person they want to clone.\u003c/p>\n\u003cp>[ad fullwidth]\u003c/p>\n\u003cp>This \"fertilized egg\" will then have to grow and develop in a surrogate mother, be born, and then have to grow up. The clone won't have any of the original's memories.\u003c/p>\n\u003cp>In essence, a clone would be more like an identical twin who has been reared apart from his or her twin. Even though identical twins reared apart have a lot of similarities, they have a lot of differences, too. One \u003ca href=\"http://www.nyas.org/publications/sciences/sci_0997_bouc.html\"> article\u003c/a> I saw put the amount of behavior/personality similarity due to genes at something around 50%.\u003c/p>\n\u003cp>And a clone will probably be more different than that. When the cell's nucleus is put into the egg, scientists erase a lot of the markings on the DNA that originally turned it into an adult cell. This \"fertilized egg\" is now a blank cell which can be shaped by both its genes AND its environment.\u003c/p>\n\u003cp>Identical twins develop in the same womb at the same time and so are exposed to the same sorts of environmental effects. A clone would not be. And these environmental factors can affect how we develop. They can even \u003ca href=\"//www.thetech.org/genetics/news.php?id=106%E2%80%9D\">alter DNA\u003c/a> and as a result, alter who we become.\u003c/p>\n\u003cp>\u003c/p>\n\u003cp> 37.332 -121.903\u003c/p>\n\n","blocks":[],"excerpt":"President Obama lifted the ban on federal funding of embryonic stem cell research last Monday. Many researchers breathed a sigh of relief as they could finally get to work using these cells to find treatments and even cures for many debilitating diseases and injuries.","status":"publish","parent":0,"modified":1237225277,"stats":{"hasAudio":false,"hasVideo":false,"hasChartOrMap":false,"iframeSrcs":[],"hasGoogleForm":false,"hasGallery":false,"hasHearkenModule":false,"hasPolis":false,"paragraphCount":12,"wordCount":443},"headData":{"title":"Why Human Cloning Shouldn't be a Big Worry | KQED","description":"President Obama lifted the ban on federal funding of embryonic stem cell research last Monday. Many researchers breathed a sigh of relief as they could finally get to work using these cells to find treatments and even cures for many debilitating diseases and injuries.","ogTitle":"","ogDescription":"","ogImgId":"","twTitle":"","twDescription":"","twImgId":""},"disqusIdentifier":"1693 http://www.kqed.org/quest/blog/?p=1693","disqusUrl":"https://ww2.kqed.org/quest/2009/03/16/why-human-cloning-shouldnt-be-a-big-worry/","disqusTitle":"Why Human Cloning Shouldn't be a Big Worry","path":"/quest/1693/why-human-cloning-shouldnt-be-a-big-worry","audioTrackLength":null,"parsedContent":[{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003cp>\u003cspan class=\"left\">\u003cimg src=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2009/03/twins.jpg\" alt=\"\">\u003cem>Identical twins are more similar to one another than a clone\u003cbr>\nwill be to the person cloned.\u003c/em>\u003c/span>President Obama lifted the ban on federal funding of embryonic stem cell research last Monday. Many researchers breathed a sigh of relief as they could finally get to work using these cells to find treatments and even cures for many debilitating diseases and injuries.\u003c/p>\n\u003cp>Of course, these cells aren't any less controversial than they were eight years ago. Researchers will still need to destroy embryos to get these cells (at least until they perfect \u003ca href=\"http://www.thetech.org/genetics/news.php?id=107\">iPS cells\u003c/a> which would make this part of the debate moot). Anyone who considers an embryo made up of a few hundred cells to be alive will protest that embryo's destruction.\u003c/p>\n\u003cp>This is a legitimate argument based on when someone believes life begins. But some protests I heard were from people worried about embryonic stem cells being used to clone humans. What I can't figure out is why anyone would want to clone someone.\u003c/p>\n\u003cp>Cloning won't be like it is in the movies. Scientists won't take a cell from someone and make an exact copy of a person who is the same age and has the same memory.\u003c/p>\n\u003cp>Instead, a human will be cloned like any other mammal. First they'll remove the DNA-containing nucleus from an egg. Then they'll fuse that egg with a cell from the person they want to clone.\u003c/p>\n\u003cp>\u003c/p>\u003c/div>","attributes":{"named":{},"numeric":[]}},{"type":"component","content":"","name":"ad","attributes":{"named":{"label":"fullwidth"},"numeric":["fullwidth"]}},{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003c/p>\n\u003cp>This \"fertilized egg\" will then have to grow and develop in a surrogate mother, be born, and then have to grow up. The clone won't have any of the original's memories.\u003c/p>\n\u003cp>In essence, a clone would be more like an identical twin who has been reared apart from his or her twin. Even though identical twins reared apart have a lot of similarities, they have a lot of differences, too. One \u003ca href=\"http://www.nyas.org/publications/sciences/sci_0997_bouc.html\"> article\u003c/a> I saw put the amount of behavior/personality similarity due to genes at something around 50%.\u003c/p>\n\u003cp>And a clone will probably be more different than that. When the cell's nucleus is put into the egg, scientists erase a lot of the markings on the DNA that originally turned it into an adult cell. This \"fertilized egg\" is now a blank cell which can be shaped by both its genes AND its environment.\u003c/p>\n\u003cp>Identical twins develop in the same womb at the same time and so are exposed to the same sorts of environmental effects. A clone would not be. And these environmental factors can affect how we develop. They can even \u003ca href=\"//www.thetech.org/genetics/news.php?id=106%E2%80%9D\">alter DNA\u003c/a> and as a result, alter who we become.\u003c/p>\n\u003cp>\u003c/p>\n\u003cp> 37.332 -121.903\u003c/p>\n\n\u003c/div>\u003c/p>","attributes":{"named":{},"numeric":[]}}],"link":"/quest/1693/why-human-cloning-shouldnt-be-a-big-worry","authors":["6177"],"categories":["quest_4","quest_12"],"tags":["quest_629","quest_848","quest_1197","quest_2790","quest_2791"],"label":"quest"}},"programsReducer":{"possible":{"id":"possible","title":"Possible","info":"Possible is hosted by entrepreneur Reid Hoffman and writer Aria Finger. Together in Possible, Hoffman and Finger lead enlightening discussions about building a brighter collective future. The show features interviews with visionary guests like Trevor Noah, Sam Altman and Janette Sadik-Khan. Possible paints an optimistic portrait of the world we can create through science, policy, business, art and our shared humanity. 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Each episode also includes a short fiction story generated by advanced AI GPT-4, serving as a thought-provoking springboard to speculate how humanity could leverage technology for good.","airtime":"SUN 2pm","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2023/08/possible-5gxfizEbKOJ-pbF5ASgxrs_.1400x1400.jpg","officialWebsiteLink":"https://www.possible.fm/","meta":{"site":"news","source":"Possible"},"link":"/radio/program/possible","subscribe":{"apple":"https://podcasts.apple.com/us/podcast/possible/id1677184070","spotify":"https://open.spotify.com/show/730YpdUSNlMyPQwNnyjp4k"}},"1a":{"id":"1a","title":"1A","info":"1A is home to the national conversation. 1A brings on great guests and frames the best debate in ways that make you think, share and engage.","airtime":"MON-THU 11pm-12am","imageSrc":"https://ww2.kqed.org/radio/wp-content/uploads/sites/50/2018/04/1a.jpg","officialWebsiteLink":"https://the1a.org/","meta":{"site":"news","source":"npr"},"link":"/radio/program/1a","subscribe":{"npr":"https://rpb3r.app.goo.gl/RBrW","apple":"https://itunes.apple.com/WebObjects/MZStore.woa/wa/viewPodcast?s=143441&mt=2&id=1188724250&at=11l79Y&ct=nprdirectory","tuneIn":"https://tunein.com/radio/1A-p947376/","rss":"https://feeds.npr.org/510316/podcast.xml"}},"all-things-considered":{"id":"all-things-considered","title":"All Things Considered","info":"Every weekday, \u003cem>All Things Considered\u003c/em> hosts Robert Siegel, Audie Cornish, Ari Shapiro, and Kelly McEvers present the program's trademark mix of news, interviews, commentaries, reviews, and offbeat features. 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And we’ll do it with your help! You ask the questions. You decide what Bay Curious investigates. 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Plus, KQED’s Bianca Taylor brings you the local KQED news you need to know.","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2022/02/Consider-This_3000_V3-copy-scaled-1.jpg","imageAlt":"Consider This from NPR and KQED","officialWebsiteLink":"/podcasts/considerthis","meta":{"site":"news","source":"kqed","order":"7"},"link":"/podcasts/considerthis","subscribe":{"apple":"https://podcasts.apple.com/podcast/id1503226625?mt=2&at=11l79Y&ct=nprdirectory","npr":"https://rpb3r.app.goo.gl/coronavirusdaily","google":"https://podcasts.google.com/feed/aHR0cHM6Ly9mZWVkcy5ucHIub3JnLzUxMDM1NS9wb2RjYXN0LnhtbA","spotify":"https://open.spotify.com/show/3Z6JdCS2d0eFEpXHKI6WqH"}},"forum":{"id":"forum","title":"Forum","tagline":"The conversation starts here","info":"KQED’s live call-in program discussing local, state, national and international issues, as well as in-depth interviews.","airtime":"MON-FRI 9am-11am, 10pm-11pm","imageSrc":"https://ww2.kqed.org/app/uploads/2022/06/forum-logo-900x900tile-1.gif","imageAlt":"KQED Forum with Mina Kim and Alexis Madrigal","officialWebsiteLink":"/forum","meta":{"site":"news","source":"kqed","order":"8"},"link":"/forum","subscribe":{"apple":"https://podcasts.apple.com/us/podcast/kqeds-forum/id73329719","google":"https://podcasts.google.com/feed/aHR0cHM6Ly9mZWVkcy5tZWdhcGhvbmUuZm0vS1FJTkM5NTU3MzgxNjMz","npr":"https://www.npr.org/podcasts/432307980/forum","stitcher":"https://www.stitcher.com/podcast/kqedfm-kqeds-forum-podcast","rss":"https://feeds.megaphone.fm/KQINC9557381633"}},"freakonomics-radio":{"id":"freakonomics-radio","title":"Freakonomics Radio","info":"Freakonomics Radio is a one-hour award-winning podcast and public-radio project hosted by Stephen Dubner, with co-author Steve Levitt as a regular guest. 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