The (Dog's) Nose Knows: Sensor Mimics Canine Sniffing Cells For Smells
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Scientists use trained sniffer dogs to \u003ca href=\"http://www.reuters.com/article/2012/04/30/us-usa-pythons-dogs-idUSBRE83T19J20120430\">track pythons in the Everglades\u003c/a> or \u003ca href=\"http://www.npr.org/2012/01/07/144752385/dog-trained-as-ultimate-whale-pooper-snooper\">find whales\u003c/a> by smelling their floating poop. And some dogs can \u003ca href=\"http://www.npr.org/2011/02/04/133498144/can-dogs-smell-cancer\">smell cancer\u003c/a> too.\u003c/p>\n\u003cp>Scientists are working to build devices that can detect odors as sensitively as a dog’s nose. Now researchers in South Korea have built a sensor that works like a dog’s nose, without using canine sniffing cells. The new device combines a simplified version of the cells in dog’s nose with tiny transistors similar to those in our computers. It senses hexanal, a chemical commonly released by rotting food.\u003c/p>\n\u003cp>When a dog takes a whiff of something (possibly stinky to us!), chemical vapors bind to matching proteins on the surface of different cells in its nose. Binding of the aroma molecule sends a cascade of charged ions coursing through the cell. Those ions create an electric field that travels through the cell. This chemical and electrical wave travels along connected cells and neurons until it reaches the dog’s brain as a nerve impulse, signaling that the animal encountered that particular smell.\u003c/p>\n\u003cp>Tai Hyun Park and \u003ca href=\"http://hnd.snu.ac.kr/hong.htm\">Seunghun Hong\u003c/a>, of \u003ca href=\"http://www.useoul.edu/\">Seoul National University\u003c/a>, with their colleagues, recreated a simplified version of the detecting cells in a dog’s nose using tiny bubbles made from cell membrane. The scientists engineered human kidney cells to produce the canine receptor protein for hexanal, a chemical released by rotting food. \u003c/p>\n\u003cp>These cells naturally contain a handful of accessory proteins that generate the ion cascade once the smell molecule binds to its receptor. The researchers shook the engineered cells and tiny bits of membrane pinched off into tiny bubbles that contained the dog receptor protein and the accessory proteins (see left side of the picture below).\u003c/p>\n\u003cfigure id=\"attachment_36529\" class=\"wp-caption aligncenter\" style=\"max-width: 640px\">\u003ca href=\"http://ww2.kqed.org/quest/2012/05/02/the-dogs-nose-knows-sensor-mimics-canine-sniffing-cells-for-smells/figure-1b_600dpi/\" rel=\"attachment wp-att-36529\">\u003cimg src=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2012/04/figure-1b_600dpi-640x295.jpg\" alt=\"\" title=\"figure-1b_600dpi\" width=\"640\" height=\"295\" class=\"size-large wp-image-36529\">\u003c/a>\u003cfigcaption class=\"wp-caption-text\">Diagram of new sensor. On right: The bubble contains dog smell receptor protein (labeled olfactory) and accessory proteins that allow calcium ions to flow inside when the receptor protein binds hexanal. The bubble sits atop a web of carbon nanotubes. Left: Calcium ions flow into the bubble when the receptor protein binds the target, hexanal. Image credit: Seunghun Hong, Seoul National University in Korea\u003c/figcaption>\u003c/figure>\n\u003cp>Then the scientists placed these bubbles atop a web of conducting carbon nanotubes, hollow cylinders made from carbon sheets. When the receptor protein in the bubble captures hexanal, the other proteins begin the chemical cascade that ends with calcium ions flowing into the bubble (right side of the picture above). \u003c/p>\n\u003cp>[ad fullwidth]\u003c/p>\n\u003cp>The new sensor does not detect the electric field created by those ions, as a dog’s brain eventually would. It measures how that electric field influences current flowing through a nanotube transistor.\u003c/p>\n\u003cp>In the transistor, carbon nanotubes stretch between two electrodes and current flows freely through the nanotubes. The positive electric field created by the ions inside the bubble repels the positive charges zipping through the carbon nanotubes. Without free flowing positive charges, the nanotube cannot easily conduct electric current. So when hexanal binds to the bubble, calcium ions rush inside and the sensor reports a decreased electric current (\u003cem>Analyst\u003c/em>, DOI: \u003ca href=\"http://dx.doi.org/10.1039/c2an16274a\">10.1039/c2an16274a\u003c/a>). The more hexanal, the lower the reported current.\u003c/p>\n\u003cp>The sensor could detect the 6-carbon hexanal chain even when it was mixed with similar chemicals 5-, 7- and 8-carbons long. It even signaled when covered with diluted spoiled milk.\u003c/p>\n\u003cp>\u003c/p>\n\u003cp>Hong says that these sensors could be used to evaluate the quality of wine, coffee and perfume by standardizing and quantifying their smells. Dogs have \u003ca href=\"%E2%80%9D\"> 220 million different smell receptors\u003c/a> (pdf). But there’s no need to make one sensor for each smell receptor in a dog’s nose, Hong says. Perhaps scientists would need 10 to 20 different sensors that correspond to the characteristic odors of the wine or coffee, he says. \u003c/p>\n\n","blocks":[],"excerpt":"Dogs have an amazingly sensitive sense of smell that allows them to find lost people, illegal drugs and even floating whale poop. A new sensor uses the same principles to sniff out rotten food. ","status":"publish","parent":0,"modified":1443831734,"stats":{"hasAudio":false,"hasVideo":false,"hasChartOrMap":false,"iframeSrcs":[],"hasGoogleForm":false,"hasGallery":false,"hasHearkenModule":false,"hasPolis":false,"paragraphCount":12,"wordCount":665},"headData":{"title":"The (Dog's) Nose Knows: Sensor Mimics Canine Sniffing Cells For Smells | KQED","description":"Dogs have an amazingly sensitive sense of smell that allows them to find lost people, illegal drugs and even floating whale poop. A new sensor uses the same principles to sniff out rotten food. ","ogTitle":"","ogDescription":"","ogImgId":"","twTitle":"","twDescription":"","twImgId":""},"disqusIdentifier":"36526 http://science.kqed.org/quest/?p=36526","disqusUrl":"https://ww2.kqed.org/quest/2012/05/02/the-dogs-nose-knows-sensor-mimics-canine-sniffing-cells-for-smells/","disqusTitle":"The (Dog's) Nose Knows: Sensor Mimics Canine Sniffing Cells For Smells","path":"/quest/36526/the-dogs-nose-knows-sensor-mimics-canine-sniffing-cells-for-smells","audioTrackLength":null,"parsedContent":[{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003cfigure id=\"attachment_36528\" class=\"wp-caption alignleft\" style=\"max-width: 300px\">\u003ca href=\"http://ww2.kqed.org/quest/2012/05/02/the-dogs-nose-knows-sensor-mimics-canine-sniffing-cells-for-smells/dog-nose-resize/\" rel=\"attachment wp-att-36528\">\u003cimg src=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2012/04/dog-nose-resize-300x169.jpg\" alt=\"dog nose macro\" title=\"dog nose resize\" width=\"300\" height=\"169\" class=\"size-thumbnail wp-image-36528\">\u003c/a>\u003cfigcaption class=\"wp-caption-text\">Image credit: Flickr/{link url=” http://www.flickr.com/photos/62468090@N00/140846900 “}great_sea{/link}\u003c/figcaption>\u003c/figure>\n\u003cp>Dogs’ amazing sense of smell can help police officers find lost people, illegal drugs or smuggled food. Scientists use trained sniffer dogs to \u003ca href=\"http://www.reuters.com/article/2012/04/30/us-usa-pythons-dogs-idUSBRE83T19J20120430\">track pythons in the Everglades\u003c/a> or \u003ca href=\"http://www.npr.org/2012/01/07/144752385/dog-trained-as-ultimate-whale-pooper-snooper\">find whales\u003c/a> by smelling their floating poop. And some dogs can \u003ca href=\"http://www.npr.org/2011/02/04/133498144/can-dogs-smell-cancer\">smell cancer\u003c/a> too.\u003c/p>\n\u003cp>Scientists are working to build devices that can detect odors as sensitively as a dog’s nose. Now researchers in South Korea have built a sensor that works like a dog’s nose, without using canine sniffing cells. The new device combines a simplified version of the cells in dog’s nose with tiny transistors similar to those in our computers. It senses hexanal, a chemical commonly released by rotting food.\u003c/p>\n\u003cp>When a dog takes a whiff of something (possibly stinky to us!), chemical vapors bind to matching proteins on the surface of different cells in its nose. Binding of the aroma molecule sends a cascade of charged ions coursing through the cell. Those ions create an electric field that travels through the cell. This chemical and electrical wave travels along connected cells and neurons until it reaches the dog’s brain as a nerve impulse, signaling that the animal encountered that particular smell.\u003c/p>\n\u003cp>Tai Hyun Park and \u003ca href=\"http://hnd.snu.ac.kr/hong.htm\">Seunghun Hong\u003c/a>, of \u003ca href=\"http://www.useoul.edu/\">Seoul National University\u003c/a>, with their colleagues, recreated a simplified version of the detecting cells in a dog’s nose using tiny bubbles made from cell membrane. The scientists engineered human kidney cells to produce the canine receptor protein for hexanal, a chemical released by rotting food. \u003c/p>\n\u003cp>These cells naturally contain a handful of accessory proteins that generate the ion cascade once the smell molecule binds to its receptor. The researchers shook the engineered cells and tiny bits of membrane pinched off into tiny bubbles that contained the dog receptor protein and the accessory proteins (see left side of the picture below).\u003c/p>\n\u003cfigure id=\"attachment_36529\" class=\"wp-caption aligncenter\" style=\"max-width: 640px\">\u003ca href=\"http://ww2.kqed.org/quest/2012/05/02/the-dogs-nose-knows-sensor-mimics-canine-sniffing-cells-for-smells/figure-1b_600dpi/\" rel=\"attachment wp-att-36529\">\u003cimg src=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2012/04/figure-1b_600dpi-640x295.jpg\" alt=\"\" title=\"figure-1b_600dpi\" width=\"640\" height=\"295\" class=\"size-large wp-image-36529\">\u003c/a>\u003cfigcaption class=\"wp-caption-text\">Diagram of new sensor. On right: The bubble contains dog smell receptor protein (labeled olfactory) and accessory proteins that allow calcium ions to flow inside when the receptor protein binds hexanal. The bubble sits atop a web of carbon nanotubes. Left: Calcium ions flow into the bubble when the receptor protein binds the target, hexanal. Image credit: Seunghun Hong, Seoul National University in Korea\u003c/figcaption>\u003c/figure>\n\u003cp>Then the scientists placed these bubbles atop a web of conducting carbon nanotubes, hollow cylinders made from carbon sheets. When the receptor protein in the bubble captures hexanal, the other proteins begin the chemical cascade that ends with calcium ions flowing into the bubble (right side of the picture above). \u003c/p>\n\u003cp>\u003c/p>\u003c/div>","attributes":{"named":{},"numeric":[]}},{"type":"component","content":"","name":"ad","attributes":{"named":{"label":"fullwidth"},"numeric":["fullwidth"]}},{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003c/p>\n\u003cp>The new sensor does not detect the electric field created by those ions, as a dog’s brain eventually would. It measures how that electric field influences current flowing through a nanotube transistor.\u003c/p>\n\u003cp>In the transistor, carbon nanotubes stretch between two electrodes and current flows freely through the nanotubes. The positive electric field created by the ions inside the bubble repels the positive charges zipping through the carbon nanotubes. Without free flowing positive charges, the nanotube cannot easily conduct electric current. So when hexanal binds to the bubble, calcium ions rush inside and the sensor reports a decreased electric current (\u003cem>Analyst\u003c/em>, DOI: \u003ca href=\"http://dx.doi.org/10.1039/c2an16274a\">10.1039/c2an16274a\u003c/a>). The more hexanal, the lower the reported current.\u003c/p>\n\u003cp>The sensor could detect the 6-carbon hexanal chain even when it was mixed with similar chemicals 5-, 7- and 8-carbons long. It even signaled when covered with diluted spoiled milk.\u003c/p>\n\u003cp>\u003c/p>\n\u003cp>Hong says that these sensors could be used to evaluate the quality of wine, coffee and perfume by standardizing and quantifying their smells. Dogs have \u003ca href=\"%E2%80%9D\"> 220 million different smell receptors\u003c/a> (pdf). But there’s no need to make one sensor for each smell receptor in a dog’s nose, Hong says. Perhaps scientists would need 10 to 20 different sensors that correspond to the characteristic odors of the wine or coffee, he says. \u003c/p>\n\n\u003c/div>\u003c/p>","attributes":{"named":{},"numeric":[]}}],"link":"/quest/36526/the-dogs-nose-knows-sensor-mimics-canine-sniffing-cells-for-smells","authors":["10331"],"categories":["quest_5","quest_8"],"tags":["quest_11045","quest_3547","quest_3351","quest_2008","quest_2349","quest_13","quest_11044","quest_11041","quest_11043"],"featImg":"quest_36528","label":"quest"},"quest_20814":{"type":"posts","id":"quest_20814","meta":{"index":"posts_1591205157","site":"quest","id":"20814","score":null,"sort":[1311111069000]},"guestAuthors":[],"slug":"puget-sound-orca-poop-is-a-treasure-trove-for-researchers","title":"Puget Sound Orca Poop is a 'Treasure Trove' for Researchers","publishDate":1311111069,"format":"standard","headTitle":"Puget Sound Orca Poop is a ‘Treasure Trove’ for Researchers | KQED","labelTerm":{"site":"quest"},"content":"\u003cfigure id=\"attachment_20835\" class=\"wp-caption alignleft\" style=\"max-width: 300px\">\u003ca href=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2011/07/AhearnAshley-KCTS-Puget_Sound_Orca_Poop_640.jpg\">\u003cimg decoding=\"async\" loading=\"lazy\" class=\"size-thumbnail wp-image-20835\" title=\"AhearnAshley-KCTS-Puget_Sound_Orca_Poop_640\" src=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2011/07/AhearnAshley-KCTS-Puget_Sound_Orca_Poop_640-300x169.jpg\" alt=\"orcas\" width=\"300\" height=\"169\">\u003c/a>\u003cfigcaption class=\"wp-caption-text\">A pod of transient orcas swim past North Pender Island in Puget Sound. Credit: Ashley Ahearn\u003c/figcaption>\u003c/figure>\n\u003cp>SAN JUAN ISLANDS, Wash. — Puzzled by orcas’ failure to thrive in Puget Sound, researchers have turned to a secret weapon with a killer nose.\u003c/p>\n\u003cp>Scientists have several hypotheses for why Puget Sound killer whales are not recovering after being added in 2005 to the federal list of endangered species. They suspect lack of food, vessel traffic and pollution are to blame, but no one knows for sure.\u003c/p>\n\u003cp>Researcher Sam Wasser and his team are finding answers in the whales’ wake. Or, more specifically, in the fecal matter they leave behind as they swim through the waters of Puget Sound.\u003c/p>\n\u003cp>“It looks like a combination of algae and snot, if you want to know the truth,” explains Wasser, the director of the \u003ca href=\"http://conservationbiology.net/research-programs/killer-whales-2/\">Center for Conservation Biology\u003c/a> at the University of Washington. “It varies in color but it’s very mucusy.”\u003c/p>\n\u003cp>But Wasser says poop’s not gross. It’s \u003ca href=\"http://earthfix.opb.org/repo/media/audio/2011/07/08/071111AA_whalepoop_web.mp3\">scientific gold\u003c/a>.\u003c/p>\n\u003cp>[ad fullwidth]\u003c/p>\n\u003cp>“We can measure the diet of the animal, we can get toxins from the feces, DNA so we can tell the individual’s identity, it’s species, sex and all of this is in feces. So it’s literally a treasure trove of information,” says Wasser.\u003c/p>\n\u003cfigure id=\"attachment_20836\" class=\"wp-caption alignleft\" style=\"max-width: 300px\">\u003ca href=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2011/07/AhearnAshley-KCTS-Puget_Sound_Orca_Poop_Image640.jpg\">\u003cimg decoding=\"async\" loading=\"lazy\" class=\"size-thumbnail wp-image-20836\" title=\"AhearnAshley-KCTS-Puget_Sound_Orca_Poop_Image640\" src=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2011/07/AhearnAshley-KCTS-Puget_Sound_Orca_Poop_Image640-300x169.jpg\" alt=\"tucker\" width=\"300\" height=\"169\">\u003c/a>\u003cfigcaption class=\"wp-caption-text\">Tucker and trainer, Liz Sealy take to the bow on the hunt for whale poop. Credit: Ashley Ahearn\u003c/figcaption>\u003c/figure>\n\u003cp>His team has developed techniques to analyze animal poop from all over the world. His center has helped prosecute ivory poachers in Africa, track wolverines in the Rockies and better understand predator-prey interactions between wolves and caribou in the tundra.\u003c/p>\n\u003cp>But finding wild animal poop, especially whale poop, isn’t easy, so Wasser has taken a creative approach to staffing his organization. Wasser looks down lovingly at his furry black sidekick.\u003c/p>\n\u003cp>“This is Tucker our scat detection dog. Say hi Tucker.”\u003c/p>\n\u003cp>Tucker is an 8-year-old black Lab mix. He’s what those in the dog world call “ball obsessed.” Tucker will do anything for a game of fetch – even if that means sniffing out floating whale poop from a mile away – because he knows that when he finds the poop he gets to play with his ball.\u003c/p>\n\u003cp> \u003c/p>\n\u003cp style=\"text-align: center\">[youtube=http://player.vimeo.com/video/26171791?title=0&byline=0&portrait=0]\u003c/p>\n\u003cp style=\"text-align: center\">\u003ca href=\"http://vimeo.com/26171791\">Tucker the scat-sniffing Lab\u003c/a> from \u003ca href=\"http://vimeo.com/earthfix\">EarthFix\u003c/a> on \u003ca href=\"http://vimeo.com\">Vimeo\u003c/a>.\u003c/p>\n\u003cp>Killer whales have been found to have the highest concentrations of toxic substances like DDT, flame-retardants and PCBs of any creature on the planet. Jessica Lundin, a graduate student at the Center for Conservation biology, says that if scientists can understand more about the contamination in these animals, they may be able to explain why they’re not recovering.\u003c/p>\n\u003cp>“These toxicants have been shown in the lab to have reproductive impairment, thyroid disruption and to be immunotoxic. Those are very concerning attributes, especially when we know this endangered population has incredibly high levels.”\u003c/p>\n\u003cp>I join Wasser and his team as they head out of their base, San Juan Island’s Snug Harbor, in search of poop samples. As we’re rounding a rocky outcropping another research pipes in over the radio with the identification numbers of a pod of killer whales spotted passing nearby North Pender Island.\u003c/p>\n\u003cp>Deborah Giles, a PhD candidate at the University of California Davis and an expert on killer whale behavior, notes down the location and steers the boat. White caps slap at the bow as we pick up speed.\u003c/p>\n\u003cp>But we’re rewarded when black dorsal fins emerge several hundred yards ahead of us.\u003c/p>\n\u003cp>“There they are!” Giles exclaims. “They’re at 11.”\u003c/p>\n\u003cp>Liz Sealy, Tucker’s trainer, is in the bow of the boat with the dog trying to pick up a scent as we criss-cross the waters where the whales last surfaced – on the lookout for poop.\u003c/p>\n\u003cp>“When he gets excited he’ll start standing up on the bow, wagging his tail, getting really animated. So for now he’s just checking the scene,” she explains.\u003c/p>\n\u003cp>Tucker wanders back and forth across the bow but doesn’t seem too excited. The researchers spend about 20 minutes bobbing along after the whales, but alas, Tucker comes up empty-snouted. The winds are too strong and the water’s too rough for him to lock onto a strong scent.\u003c/p>\n\u003cp>Despite this unlucky mission, the team will continue to collect samples from killer whales in these waters throughout the summer.\u003c/p>\n\u003cp>With samples collected in the past, Wasser’s team has been able to show that during periods of high vessel traffic – say Fourth of July weekend for example – the whales have higher levels of stress hormones in their poop. Combine that with smaller runs of Chinook salmon, which the whales prefer, and you’ve got problems.\u003c/p>\n\u003cfigure id=\"attachment_20838\" class=\"wp-caption alignright\" style=\"max-width: 300px\">\u003ca href=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2011/07/AhearnAshley-KCTS-Puget_Sound_Orca_Poop_Image_2_640.jpg\">\u003cimg decoding=\"async\" loading=\"lazy\" class=\"size-thumbnail wp-image-20838\" title=\"AhearnAshley-KCTS-Puget_Sound_Orca_Poop_Image_2_640\" src=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2011/07/AhearnAshley-KCTS-Puget_Sound_Orca_Poop_Image_2_640-300x169.jpg\" alt=\"\" width=\"300\" height=\"169\">\u003c/a>\u003cfigcaption class=\"wp-caption-text\">Killer Whale food. Toxic chemicals accumulate in the blubber of marine mammals – the primary food source of transient orcas. Credit: Ashley Ahearn\u003c/figcaption>\u003c/figure>\n\u003cp>“The data suggests that at times of low prey abundance there’s a cumulative impact of boat traffic. The whales are more stressed,” says Katherine Ayres, a graduate student with the Center for Conservation Biology. The researchers can also tell when the whales are undernourished and correlate that with lower fertility rates and higher mortality.\u003c/p>\n\u003cp>There are about 86 resident killer whales in the region and that number hasn’t increased since 2000 when the population crashed. Wasser suspects that the toxic chemicals in these whales may be playing a role here because they disrupt major hormonal pathways.\u003c/p>\n\u003cp>“They disrupt major hormonal pathways so that your body’s ability to regulate reproduction, metabolism all those things can be negatively impacted,” he says. “It’s accumulating effects that are occurring and we’re just trying to show the mechanisms that lead to that outcome.”\u003c/p>\n\u003cp>For Deborah Giles, that outcome is pretty clear. “There are females that haven’t had calves yet and really they should have been having calves by now. Also we’re losing males that are just coming into reproductive age. That’s a huge hit to this population.”\u003c/p>\n\u003cp>It’s tricky to pick apart the various factors that make life tough for orca whales. Lack of food, vessel traffic and toxic pollution all pose a threat to these animals but by studying poop, scientists can look at all these things collectively — providing some direction for policymakers who are trying to solve human global health problems.\u003c/p>\n\u003cp>Wasser says a sample of whale poop is kind of like a snapshot of pollution levels in our coastal waters and that’s a photograph we might all want to have a look at.\u003c/p>\n\u003cp>[ad floatright]\u003c/p>\n\u003cp>\u003ca href=\"http://earthfix.kcts9.org/\">EarthFix\u003c/a> is a public media project of Oregon Public Broadcasting and Boise State Public Radio, Idaho Public Television, KCTS 9 Seattle, KUOW Puget Sound Public Radio, Northwest Public Radio and Television, Southern Oregon Public Television and the Corporation for Public Broadcasting.\u003c/p>\n\n","blocks":[],"excerpt":"Scientists are looking for clues in killer whales' aquatic droppings as they try to determine why their numbers remain so low in Puget Sound. To sniff out these floating data dumps, researchers have turned to a furry colleague named Tucker.","status":"publish","parent":0,"modified":1684974006,"stats":{"hasAudio":false,"hasVideo":true,"hasChartOrMap":false,"iframeSrcs":[],"hasGoogleForm":false,"hasGallery":false,"hasHearkenModule":false,"hasPolis":false,"paragraphCount":30,"wordCount":1208},"headData":{"title":"Puget Sound Orca Poop is a 'Treasure Trove' for Researchers | KQED","description":"Scientists are looking for clues in killer whales' aquatic droppings as they try to determine why their numbers remain so low in Puget Sound. To sniff out these floating data dumps, researchers have turned to a furry colleague named Tucker.","ogTitle":"","ogDescription":"","ogImgId":"","twTitle":"","twDescription":"","twImgId":""},"templateType":"standard","featuredImageType":"standard","excludeFromSiteSearch":"Include","articleAge":"0","path":"/quest/20814/puget-sound-orca-poop-is-a-treasure-trove-for-researchers","audioUrl":"http://earthfix.opb.org/repo/media/audio/2011/07/08/071111AA_whalepoop_web.mp3","audioDuration":null,"audioTrackLength":null,"parsedContent":[{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003cfigure id=\"attachment_20835\" class=\"wp-caption alignleft\" style=\"max-width: 300px\">\u003ca href=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2011/07/AhearnAshley-KCTS-Puget_Sound_Orca_Poop_640.jpg\">\u003cimg decoding=\"async\" loading=\"lazy\" class=\"size-thumbnail wp-image-20835\" title=\"AhearnAshley-KCTS-Puget_Sound_Orca_Poop_640\" src=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2011/07/AhearnAshley-KCTS-Puget_Sound_Orca_Poop_640-300x169.jpg\" alt=\"orcas\" width=\"300\" height=\"169\">\u003c/a>\u003cfigcaption class=\"wp-caption-text\">A pod of transient orcas swim past North Pender Island in Puget Sound. Credit: Ashley Ahearn\u003c/figcaption>\u003c/figure>\n\u003cp>SAN JUAN ISLANDS, Wash. — Puzzled by orcas’ failure to thrive in Puget Sound, researchers have turned to a secret weapon with a killer nose.\u003c/p>\n\u003cp>Scientists have several hypotheses for why Puget Sound killer whales are not recovering after being added in 2005 to the federal list of endangered species. They suspect lack of food, vessel traffic and pollution are to blame, but no one knows for sure.\u003c/p>\n\u003cp>Researcher Sam Wasser and his team are finding answers in the whales’ wake. Or, more specifically, in the fecal matter they leave behind as they swim through the waters of Puget Sound.\u003c/p>\n\u003cp>“It looks like a combination of algae and snot, if you want to know the truth,” explains Wasser, the director of the \u003ca href=\"http://conservationbiology.net/research-programs/killer-whales-2/\">Center for Conservation Biology\u003c/a> at the University of Washington. “It varies in color but it’s very mucusy.”\u003c/p>\n\u003cp>But Wasser says poop’s not gross. It’s \u003ca href=\"http://earthfix.opb.org/repo/media/audio/2011/07/08/071111AA_whalepoop_web.mp3\">scientific gold\u003c/a>.\u003c/p>\n\u003cp>\u003c/p>\u003c/div>","attributes":{"named":{},"numeric":[]}},{"type":"component","content":"","name":"ad","attributes":{"named":{"label":"fullwidth"},"numeric":["fullwidth"]}},{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003c/p>\n\u003cp>“We can measure the diet of the animal, we can get toxins from the feces, DNA so we can tell the individual’s identity, it’s species, sex and all of this is in feces. So it’s literally a treasure trove of information,” says Wasser.\u003c/p>\n\u003cfigure id=\"attachment_20836\" class=\"wp-caption alignleft\" style=\"max-width: 300px\">\u003ca href=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2011/07/AhearnAshley-KCTS-Puget_Sound_Orca_Poop_Image640.jpg\">\u003cimg decoding=\"async\" loading=\"lazy\" class=\"size-thumbnail wp-image-20836\" title=\"AhearnAshley-KCTS-Puget_Sound_Orca_Poop_Image640\" src=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2011/07/AhearnAshley-KCTS-Puget_Sound_Orca_Poop_Image640-300x169.jpg\" alt=\"tucker\" width=\"300\" height=\"169\">\u003c/a>\u003cfigcaption class=\"wp-caption-text\">Tucker and trainer, Liz Sealy take to the bow on the hunt for whale poop. Credit: Ashley Ahearn\u003c/figcaption>\u003c/figure>\n\u003cp>His team has developed techniques to analyze animal poop from all over the world. His center has helped prosecute ivory poachers in Africa, track wolverines in the Rockies and better understand predator-prey interactions between wolves and caribou in the tundra.\u003c/p>\n\u003cp>But finding wild animal poop, especially whale poop, isn’t easy, so Wasser has taken a creative approach to staffing his organization. Wasser looks down lovingly at his furry black sidekick.\u003c/p>\n\u003cp>“This is Tucker our scat detection dog. Say hi Tucker.”\u003c/p>\n\u003cp>Tucker is an 8-year-old black Lab mix. He’s what those in the dog world call “ball obsessed.” Tucker will do anything for a game of fetch – even if that means sniffing out floating whale poop from a mile away – because he knows that when he finds the poop he gets to play with his ball.\u003c/p>\n\u003cp> \u003c/p>\n\u003cp style=\"text-align: center\">\u003c/p>\u003cp>null\u003c/p>\u003cp>\u003c/p>\n\u003cp style=\"text-align: center\">\u003ca href=\"http://vimeo.com/26171791\">Tucker the scat-sniffing Lab\u003c/a> from \u003ca href=\"http://vimeo.com/earthfix\">EarthFix\u003c/a> on \u003ca href=\"http://vimeo.com\">Vimeo\u003c/a>.\u003c/p>\n\u003cp>Killer whales have been found to have the highest concentrations of toxic substances like DDT, flame-retardants and PCBs of any creature on the planet. Jessica Lundin, a graduate student at the Center for Conservation biology, says that if scientists can understand more about the contamination in these animals, they may be able to explain why they’re not recovering.\u003c/p>\n\u003cp>“These toxicants have been shown in the lab to have reproductive impairment, thyroid disruption and to be immunotoxic. Those are very concerning attributes, especially when we know this endangered population has incredibly high levels.”\u003c/p>\n\u003cp>I join Wasser and his team as they head out of their base, San Juan Island’s Snug Harbor, in search of poop samples. As we’re rounding a rocky outcropping another research pipes in over the radio with the identification numbers of a pod of killer whales spotted passing nearby North Pender Island.\u003c/p>\n\u003cp>Deborah Giles, a PhD candidate at the University of California Davis and an expert on killer whale behavior, notes down the location and steers the boat. White caps slap at the bow as we pick up speed.\u003c/p>\n\u003cp>But we’re rewarded when black dorsal fins emerge several hundred yards ahead of us.\u003c/p>\n\u003cp>“There they are!” Giles exclaims. “They’re at 11.”\u003c/p>\n\u003cp>Liz Sealy, Tucker’s trainer, is in the bow of the boat with the dog trying to pick up a scent as we criss-cross the waters where the whales last surfaced – on the lookout for poop.\u003c/p>\n\u003cp>“When he gets excited he’ll start standing up on the bow, wagging his tail, getting really animated. So for now he’s just checking the scene,” she explains.\u003c/p>\n\u003cp>Tucker wanders back and forth across the bow but doesn’t seem too excited. The researchers spend about 20 minutes bobbing along after the whales, but alas, Tucker comes up empty-snouted. The winds are too strong and the water’s too rough for him to lock onto a strong scent.\u003c/p>\n\u003cp>Despite this unlucky mission, the team will continue to collect samples from killer whales in these waters throughout the summer.\u003c/p>\n\u003cp>With samples collected in the past, Wasser’s team has been able to show that during periods of high vessel traffic – say Fourth of July weekend for example – the whales have higher levels of stress hormones in their poop. Combine that with smaller runs of Chinook salmon, which the whales prefer, and you’ve got problems.\u003c/p>\n\u003cfigure id=\"attachment_20838\" class=\"wp-caption alignright\" style=\"max-width: 300px\">\u003ca href=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2011/07/AhearnAshley-KCTS-Puget_Sound_Orca_Poop_Image_2_640.jpg\">\u003cimg decoding=\"async\" loading=\"lazy\" class=\"size-thumbnail wp-image-20838\" title=\"AhearnAshley-KCTS-Puget_Sound_Orca_Poop_Image_2_640\" src=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2011/07/AhearnAshley-KCTS-Puget_Sound_Orca_Poop_Image_2_640-300x169.jpg\" alt=\"\" width=\"300\" height=\"169\">\u003c/a>\u003cfigcaption class=\"wp-caption-text\">Killer Whale food. Toxic chemicals accumulate in the blubber of marine mammals – the primary food source of transient orcas. Credit: Ashley Ahearn\u003c/figcaption>\u003c/figure>\n\u003cp>“The data suggests that at times of low prey abundance there’s a cumulative impact of boat traffic. The whales are more stressed,” says Katherine Ayres, a graduate student with the Center for Conservation Biology. The researchers can also tell when the whales are undernourished and correlate that with lower fertility rates and higher mortality.\u003c/p>\n\u003cp>There are about 86 resident killer whales in the region and that number hasn’t increased since 2000 when the population crashed. 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And by studying cancers in dogs, we may discover new treatments for cancer in human and canine cancer patients.","status":"publish","parent":0,"modified":1457807620,"stats":{"hasAudio":false,"hasVideo":false,"hasChartOrMap":false,"iframeSrcs":[],"hasGoogleForm":false,"hasGallery":false,"hasHearkenModule":false,"hasPolis":false,"paragraphCount":5,"wordCount":87},"headData":{"title":"Fido Fights Cancer | KQED","description":"Humans and dogs have been partners for thousands of years. Now our canine friends are joining the fight against cancer. Researchers are training dogs to smell cancer in the breath samples of human patients. 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And by studying cancers in dogs, we may discover new treatments for cancer in human and canine cancer patients.\u003c/p>\n\u003cp>\u003cem>Learn more about \u003ca href=\"http://ww2.kqed.org/quest/2008/11/25/producers-notes-fido-fights-cancer/\" target=\"_blank\">these treatments and this video\u003c/a> with the Producer's Notes.\u003cbr>\n\u003c/em>\u003c/p>\n\u003cp>\u003c/p>\u003c/div>","attributes":{"named":{},"numeric":[]}},{"type":"component","content":"","name":"ad","attributes":{"named":{"label":"fullwidth"},"numeric":["fullwidth"]}},{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003c/p>\u003cp>\u003c/p>\n\u003c/div>\u003c/p>","attributes":{"named":{},"numeric":[]}}],"link":"/quest/17458/fido-fights-cancer","authors":["10169","2100"],"categories":["quest_12","quest_3422","quest_3233"],"tags":["quest_475","quest_3547","quest_3351","quest_2141","quest_2349","quest_13","quest_2893","quest_3022"],"featImg":"quest_22861","label":"quest"}},"programsReducer":{"possible":{"id":"possible","title":"Possible","info":"Possible is hosted by entrepreneur Reid Hoffman and writer Aria Finger. 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