Nobel Prize for 'Landmark' Cancer Research Conducted at UC Berkeley
Nobel Prizes Grapple With Widespread Gender Disparity
Keeping Internal Clocks Regular Sets Stage for Good Health
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Berkeley","publishDate":1538417110,"format":"aside","headTitle":"KQED Future of You | KQED Science","labelTerm":{},"content":"\u003cp>https://www.youtube.com/watch?time_continue=899&v=ScuTG1bzSHY\u003c/p>\n\u003cp>The Nobel Prize in medicine was awarded Monday to two researchers from the United States and Japan for advances in discovering how the body’s immune system can fight off the scourge of cancer.[contextly_sidebar id=\"CWuF65jUQjKNMEH73SFwE7Eh0o965day\"]\u003c/p>\n\u003cp>The $1.01 million prize will be shared by James Allison and Tasuku Honjo.\u003c/p>\n\u003cp>Allison conducted his research at the University of California-Berkeley and is now at the M.D. Anderson cancer center in Houston. Honju works at Japan’s Kyoto University.\u003c/p>\n\u003cp>Their parallel work concerned proteins that act as brakes on the body’s immune system and it constitutes “a landmark in our fight against cancer,” said a statement from the Nobel Assembly of Sweden’s Karolinska Institute, which selects winners of the annual prestigious award.\u003c/p>\n\u003cp>[ad fullwidth]\u003c/p>\n\u003cp>Allison studied a known protein and developed the concept into a new treatment approach, while Honjo discovered a new protein that also operated as a brake on immune cells.\u003c/p>\n\u003cp>“I’m honored and humbled to receive this prestigious recognition,” Allison said in a statement released by the university’s MD Anderson Cancer Center in Houston, where he is a professor.\u003c/p>\n\u003cp>“A driving motivation for scientists is simply to push the frontiers of knowledge. I didn’t set out to study cancer, but to understand the biology of T cells, these incredible cells that travel our bodies and work to protect us,” he said.[contextly_sidebar id=\"TrEVYlEaRWGIwxl3wZCxQN7b50EP4tx2\"]\u003c/p>\n\u003cp>Allison takes care in his statement to give credit to “a succession of graduate students, postdoctoral fellows and colleagues at MD Anderson, the University of California, Berkeley, and Memorial Sloan Kettering Cancer Center” who joined in the research.\u003c/p>\n\u003cp>Allison’s and Honjo’s prize-winning work started in the 1990s and was part of significant advances in cancer immunotherapy.\u003c/p>\n\u003cp>“In some patients, this therapy is remarkably effective,” Jeremy Berg, editor-in-chief of the \u003cem>Science\u003c/em> family of journals, told The Associated Press. “The number of different types of cancers for which this approach to immunotherapy is being found to be effective in at least some patients continues to grow.”\u003c/p>\n\u003cp>Therapy developed from Honjo’s work led to long-term remission in patients with metastatic cancer that had been considered essentially untreatable, the Nobel Assembly said.[contextly_sidebar id=\"JxHmQ4y9gmGqrPe0YiiMCtrrGiOV1Oid\"]\u003c/p>\n\u003cp>Berg said that former President Jimmy Carter’s cancer, which had spread to his brain, was treated with one of the drugs developed from Honjo’s work.\u003c/p>\n\u003cp>\u003c/p>\n\u003cp>The physics prize is to be announced Tuesday, followed by chemistry. The winner of the Nobel Peace Prize will be named Friday and the economics laureate will be announced next Monday. No literature prize is being given this year.\u003c/p>\n\n","blocks":[],"excerpt":"The research, which has led to drugs that release the brakes on the immune system, constitutes “a landmark\" in the fight against cancer.","status":"publish","parent":0,"modified":1538445547,"stats":{"hasAudio":false,"hasVideo":true,"hasChartOrMap":false,"iframeSrcs":[],"hasGoogleForm":false,"hasGallery":false,"hasHearkenModule":false,"hasPolis":false,"paragraphCount":15,"wordCount":471},"headData":{"title":"Nobel Prize for 'Landmark' Cancer Research Conducted at UC Berkeley | KQED","description":"The research, which has led to drugs that release the brakes on the immune system, constitutes “a landmark" in the fight against cancer.","ogTitle":"","ogDescription":"","ogImgId":"","twTitle":"","twDescription":"","twImgId":"","schema":{"@context":"http://schema.org","@type":"Article","headline":"Nobel Prize for 'Landmark' Cancer Research Conducted at UC Berkeley","datePublished":"2018-10-01T18:05:10.000Z","dateModified":"2018-10-02T01:59:07.000Z","image":"https://cdn.kqed.org/wp-content/uploads/2020/02/KQED-OG-Image@1x.png"}},"disqusIdentifier":"444705 https://ww2.kqed.org/futureofyou/?p=444705","disqusUrl":"https://ww2.kqed.org/futureofyou/2018/10/01/nobel-prize-for-landmark-cancer-research-conducted-at-berkeley/","disqusTitle":"Nobel Prize for 'Landmark' Cancer Research Conducted at UC Berkeley","source":"Events","nprByline":"David Keyton\u003cbr />Jim Heintz \u003cbr />The Associated Press","path":"/futureofyou/444705/nobel-prize-for-landmark-cancer-research-conducted-at-berkeley","audioTrackLength":null,"parsedContent":[{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003c/p>\u003cp>\u003cspan class='utils-parseShortcode-shortcodes-__youtubeShortcode__embedYoutube'>\n \u003cspan class='utils-parseShortcode-shortcodes-__youtubeShortcode__embedYoutubeInside'>\n \u003ciframe\n loading='lazy'\n class='utils-parseShortcode-shortcodes-__youtubeShortcode__youtubePlayer'\n type='text/html'\n src='//www.youtube.com/embed/ScuTG1bzSHY'\n title='//www.youtube.com/embed/ScuTG1bzSHY'\n allowfullscreen='true'\n style='border:0;'>\u003c/iframe>\n \u003c/span>\n \u003c/span>\u003c/p>\u003cp>\u003cp>The Nobel Prize in medicine was awarded Monday to two researchers from the United States and Japan for advances in discovering how the body’s immune system can fight off the scourge of cancer.\u003c/p>\u003cp>\u003c/p>\u003cp>\u003c/p>\n\u003cp>The $1.01 million prize will be shared by James Allison and Tasuku Honjo.\u003c/p>\n\u003cp>Allison conducted his research at the University of California-Berkeley and is now at the M.D. Anderson cancer center in Houston. Honju works at Japan’s Kyoto University.\u003c/p>\n\u003cp>Their parallel work concerned proteins that act as brakes on the body’s immune system and it constitutes “a landmark in our fight against cancer,” said a statement from the Nobel Assembly of Sweden’s Karolinska Institute, which selects winners of the annual prestigious award.\u003c/p>\n\u003cp>\u003c/p>\u003c/div>","attributes":{"named":{},"numeric":[]}},{"type":"component","content":"","name":"ad","attributes":{"named":{"label":"fullwidth"},"numeric":["fullwidth"]}},{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003c/p>\n\u003cp>Allison studied a known protein and developed the concept into a new treatment approach, while Honjo discovered a new protein that also operated as a brake on immune cells.\u003c/p>\n\u003cp>“I’m honored and humbled to receive this prestigious recognition,” Allison said in a statement released by the university’s MD Anderson Cancer Center in Houston, where he is a professor.\u003c/p>\n\u003cp>“A driving motivation for scientists is simply to push the frontiers of knowledge. I didn’t set out to study cancer, but to understand the biology of T cells, these incredible cells that travel our bodies and work to protect us,” he said.\u003c/p>\u003cp>\u003c/p>\u003cp>\u003c/p>\n\u003cp>Allison takes care in his statement to give credit to “a succession of graduate students, postdoctoral fellows and colleagues at MD Anderson, the University of California, Berkeley, and Memorial Sloan Kettering Cancer Center” who joined in the research.\u003c/p>\n\u003cp>Allison’s and Honjo’s prize-winning work started in the 1990s and was part of significant advances in cancer immunotherapy.\u003c/p>\n\u003cp>“In some patients, this therapy is remarkably effective,” Jeremy Berg, editor-in-chief of the \u003cem>Science\u003c/em> family of journals, told The Associated Press. “The number of different types of cancers for which this approach to immunotherapy is being found to be effective in at least some patients continues to grow.”\u003c/p>\n\u003cp>Therapy developed from Honjo’s work led to long-term remission in patients with metastatic cancer that had been considered essentially untreatable, the Nobel Assembly said.\u003c/p>\u003cp>\u003c/p>\u003cp>\u003c/p>\n\u003cp>Berg said that former President Jimmy Carter’s cancer, which had spread to his brain, was treated with one of the drugs developed from Honjo’s work.\u003c/p>\n\u003cp>\u003c/p>\n\u003cp>The physics prize is to be announced Tuesday, followed by chemistry. The winner of the Nobel Peace Prize will be named Friday and the economics laureate will be announced next Monday. No literature prize is being given this year.\u003c/p>\n\n\u003c/div>\u003c/p>","attributes":{"named":{},"numeric":[]}}],"link":"/futureofyou/444705/nobel-prize-for-landmark-cancer-research-conducted-at-berkeley","authors":["byline_futureofyou_444705"],"categories":["futureofyou_1","futureofyou_73"],"tags":["futureofyou_103","futureofyou_686","futureofyou_80","futureofyou_607"],"collections":["futureofyou_1097"],"featImg":"futureofyou_444717","label":"source_futureofyou_444705"},"futureofyou_444697":{"type":"posts","id":"futureofyou_444697","meta":{"index":"posts_1591205157","site":"futureofyou","id":"444697","score":null,"sort":[1538416835000]},"guestAuthors":[],"slug":"nobel-prizes-grapple-with-widespread-gender-disparity","title":"Nobel Prizes Grapple With Widespread Gender Disparity","publishDate":1538416835,"format":"standard","headTitle":"KQED Future of You | KQED Science","labelTerm":{},"content":"\u003cp>Nobel Prizes are the most prestigious awards on the planet but the aura of this year’s announcements has been dulled by questions over why so few women have entered the pantheon, particularly in the sciences.[contextly_sidebar id=\"5nZZhIC3YSdDRR5T9grpgNBAhed2FV9J\"]\u003c/p>\n\u003cp>The march of Nobel announcements begins Monday with the physiology/medicine prize.\u003c/p>\n\u003cp>Since the first prizes were awarded in 1901, 892 individuals have received one, but just 48 of them have been women. Thirty of those women won either the literature or peace prize, highlighting the wide gender gap in the laureates for physics, chemistry and physiology/medicine. In addition, only one woman has won for the economics prize, which is not technically a Nobel but is associated with the prizes.\u003c/p>\n\u003cdiv id=\"div-gpt-ad-1470255291270-0\" class=\"ad-placeholder\">\n\u003cp>Some of the disparity likely can be attributed to underlying structural reasons, such as the low representation of women in high-level science. The American Institute of Physics, for example, says in 2014, only 10 percent of full physics professorships were held by women.\u003c/p>\n\u003cp>But critics suggest that gender bias pervades the process of nominations, which come largely from tenured professors.\u003c/p>\n\u003cp>“The problem is the whole nomination process, you have these tenured professors who feel like they are untouchable. They can get away with everything from sexual harassment to micro-aggressions like assuming the woman in the room will take the notes, or be leaving soon to have babies,” said Anne-Marie Imafidon, the head of Stemettes, a British group that encourages girls and young women to pursue careers in science, technology, engineering and mathematics.\u003c/p>\n\u003cp>“It’s little wonder that these people aren’t putting women forward for nominations. We need to be better at telling the stories of the women in science who are doing good things and actually getting recognition,” she said.[contextly_sidebar id=\"aUoC2OWK8qLbmqMMaIEkYePe6WoqBWuM\"]\u003c/p>\n\u003cp>Powerful men taking credit for the ideas and elbow grease of their female colleagues was turned on its head in 1903 when Pierre Curie made it clear he would not accept the physics prize unless his wife and fellow researcher Marie Curie was jointly honored. She was the first female winner of any Nobel prize, but only one other woman has won the physics prize since then.\u003c/p>\n\u003cp>More than 70 years later, Jocelyn Bell, a post-graduate student at Cambridge, was overlooked for the physics prize despite her crucial contribution to the discovery of pulsars. Her supervisor, Antony Hewish, took all of the Nobel credit.\u003c/p>\n\u003c/div>\n\u003cp>Brian Keating, a physics professor at the University of California San Diego and author of the book “Losing the Nobel Prize: A Story of Cosmology, Ambition, and the Perils of Science’s Highest Honor,” says the Nobel Foundation should lift its restrictions on re-awarding for a breakthrough if an individual has been overlooked. He also says posthumous awards also should be considered and there should be no restriction on the number of individuals who can share a prize. Today the limit is three people for one prize.\u003c/p>\n\u003cp>“These measures would go a long way to addressing the injustice that so few of the brilliant women who have contributed so much to science through the years have been overlooked,” he said.\u003c/p>\n\u003cp>[ad fullwidth]\u003c/p>\n\u003cp>Keating fears that simply accepting the disparity as structural will seriously harm the prestige of all the Nobel prizes.\u003c/p>\n\u003cp>“I think with the Hollywood #MeToo movement, it has already happened in the film prizes. It has happened with the literature prize. There is no fundamental law of nature that the Nobel science prizes will continue to be seen as the highest accolade,” he said.\u003c/p>\n\u003cp>This year’s absence of a \u003ca href=\"https://apnews.com/d79fdb57df9148f98ba42afff1958ffb\">Nobel Literature prize\u003c/a> , which has been won by 14 women, puts an even sharper focus on the gender gap in science prizes.\u003c/p>\n\u003cp>The Swedish Academy, which awards the literature prize, said it would not pick a winner this year after sex abuse allegations and financial crimes scandals rocked the secretive panel, sharply dividing its 18 members, who are appointed for life. Seven members quit or distanced themselves from academy. Its permanent secretary, Anders Olsson, said the academy wanted “to commit time to recovering public confidence.”\u003c/p>\n\u003cp>The academy plans to award both the 2018 prize and the 2019 prize next year — but even that is not guaranteed. The head of the Nobel Foundation, Lars Heikensten, has warned that if the Swedish Academy does not resolve its tarnished image another group could be chosen to select the literature prize each year.\u003c/p>\n\u003cp>Stung by criticism about the diversity gap between former prize winners, the Nobel Foundation has asked that the science awarding panels for 2019 ask nominators to consider their own biases in the thousands of letters they send to solicit Nobel nominations.\u003c/p>\n\u003cp>“I am eager to see more nominations for women so they can be considered,” said Goran Hansson, secretary-general of the Royal Swedish Academy of Sciences and vice chairman of the Nobel Foundation. “We have written to nominators asking them to make sure they do not miss women or people of other ethnicities or nationalities in their nominations. We hope this will make a difference for 2019.”\u003c/p>\n\u003cp>It’s not the first time that Nobel officials have sought diversity. In his 1895 will, prize founder Alfred Nobel wrote: “It is my express wish that in the awarding of the prizes no consideration shall be given to national affiliations of any kind, so that the most worthy shall receive the prize, whether he be Scandinavian or not.”\u003c/p>\n\u003cp>Even so, the prizes remained overwhelmingly white and male for most of their existence.\u003c/p>\n\u003cp>For the first 70 years, the peace prize skewed heavily toward Western white men, with just two of the 59 prizes awarded to individuals or institutions based outside Europe or North America. Only three of the winners in that period were female.\u003c/p>\n\u003cp>The 1973 peace prize shared by North Vietnam’s Le Duc Tho and American Henry Kissinger widened the horizons — since then more than half the Nobel Peace prizes have gone to African or Asian individuals or institutions.\u003c/p>\n\u003cp>Since 2000, six women have won the peace prize.\u003c/p>\n\u003cp>[ad floatright]\u003c/p>\n\u003cp>After the medicine prize on Monday, the Royal Swedish Academy of Sciences will announce the Nobel in physics on Tuesday and in chemistry on Wednesday, while the Nobel Peace Prize will be awarded Friday by the Norwegian Nobel Committee. On Oct. 8, Sweden’s Central Bank announces the winner of the economics prize, given in honor of Alfred Nobel.\u003c/p>\n\u003cdiv id=\"div-gpt-ad-1470255291270-0\" class=\"ad-placeholder\">\n\u003cp> \u003c/p>\n\u003c/div>\n\n","blocks":[],"excerpt":"Since the first prizes were awarded in 1901, 892 individuals have received one, but just 48 of them have been women. What is to account for the gender disparity?","status":"publish","parent":0,"modified":1538374693,"stats":{"hasAudio":false,"hasVideo":false,"hasChartOrMap":false,"iframeSrcs":[],"hasGoogleForm":false,"hasGallery":false,"hasHearkenModule":false,"hasPolis":false,"paragraphCount":26,"wordCount":1095},"headData":{"title":"Nobel Prizes Grapple With Widespread Gender Disparity | KQED","description":"Since the first prizes were awarded in 1901, 892 individuals have received one, but just 48 of them have been women. What is to account for the gender disparity?","ogTitle":"","ogDescription":"","ogImgId":"","twTitle":"","twDescription":"","twImgId":"","schema":{"@context":"http://schema.org","@type":"Article","headline":"Nobel Prizes Grapple With Widespread Gender Disparity","datePublished":"2018-10-01T18:00:35.000Z","dateModified":"2018-10-01T06:18:13.000Z","image":"https://cdn.kqed.org/wp-content/uploads/2020/02/KQED-OG-Image@1x.png"}},"disqusIdentifier":"444697 https://ww2.kqed.org/futureofyou/?p=444697","disqusUrl":"https://ww2.kqed.org/futureofyou/2018/10/01/nobel-prizes-grapple-with-widespread-gender-disparity/","disqusTitle":"Nobel Prizes Grapple With Widespread Gender Disparity","source":"Events","nprByline":"Mark Lewis\u003cbr />The Associated Press","path":"/futureofyou/444697/nobel-prizes-grapple-with-widespread-gender-disparity","audioTrackLength":null,"parsedContent":[{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003cp>Nobel Prizes are the most prestigious awards on the planet but the aura of this year’s announcements has been dulled by questions over why so few women have entered the pantheon, particularly in the sciences.\u003c/p>\u003cp>\u003c/p>\u003cp>\u003c/p>\n\u003cp>The march of Nobel announcements begins Monday with the physiology/medicine prize.\u003c/p>\n\u003cp>Since the first prizes were awarded in 1901, 892 individuals have received one, but just 48 of them have been women. Thirty of those women won either the literature or peace prize, highlighting the wide gender gap in the laureates for physics, chemistry and physiology/medicine. In addition, only one woman has won for the economics prize, which is not technically a Nobel but is associated with the prizes.\u003c/p>\n\u003cdiv id=\"div-gpt-ad-1470255291270-0\" class=\"ad-placeholder\">\n\u003cp>Some of the disparity likely can be attributed to underlying structural reasons, such as the low representation of women in high-level science. The American Institute of Physics, for example, says in 2014, only 10 percent of full physics professorships were held by women.\u003c/p>\n\u003cp>But critics suggest that gender bias pervades the process of nominations, which come largely from tenured professors.\u003c/p>\n\u003cp>“The problem is the whole nomination process, you have these tenured professors who feel like they are untouchable. They can get away with everything from sexual harassment to micro-aggressions like assuming the woman in the room will take the notes, or be leaving soon to have babies,” said Anne-Marie Imafidon, the head of Stemettes, a British group that encourages girls and young women to pursue careers in science, technology, engineering and mathematics.\u003c/p>\n\u003cp>“It’s little wonder that these people aren’t putting women forward for nominations. We need to be better at telling the stories of the women in science who are doing good things and actually getting recognition,” she said.\u003c/p>\u003cp>\u003c/p>\u003cp>\u003c/p>\n\u003cp>Powerful men taking credit for the ideas and elbow grease of their female colleagues was turned on its head in 1903 when Pierre Curie made it clear he would not accept the physics prize unless his wife and fellow researcher Marie Curie was jointly honored. She was the first female winner of any Nobel prize, but only one other woman has won the physics prize since then.\u003c/p>\n\u003cp>More than 70 years later, Jocelyn Bell, a post-graduate student at Cambridge, was overlooked for the physics prize despite her crucial contribution to the discovery of pulsars. Her supervisor, Antony Hewish, took all of the Nobel credit.\u003c/p>\n\u003c/div>\n\u003cp>Brian Keating, a physics professor at the University of California San Diego and author of the book “Losing the Nobel Prize: A Story of Cosmology, Ambition, and the Perils of Science’s Highest Honor,” says the Nobel Foundation should lift its restrictions on re-awarding for a breakthrough if an individual has been overlooked. He also says posthumous awards also should be considered and there should be no restriction on the number of individuals who can share a prize. Today the limit is three people for one prize.\u003c/p>\n\u003cp>“These measures would go a long way to addressing the injustice that so few of the brilliant women who have contributed so much to science through the years have been overlooked,” he said.\u003c/p>\n\u003cp>\u003c/p>\u003c/div>","attributes":{"named":{},"numeric":[]}},{"type":"component","content":"","name":"ad","attributes":{"named":{"label":"fullwidth"},"numeric":["fullwidth"]}},{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003c/p>\n\u003cp>Keating fears that simply accepting the disparity as structural will seriously harm the prestige of all the Nobel prizes.\u003c/p>\n\u003cp>“I think with the Hollywood #MeToo movement, it has already happened in the film prizes. It has happened with the literature prize. There is no fundamental law of nature that the Nobel science prizes will continue to be seen as the highest accolade,” he said.\u003c/p>\n\u003cp>This year’s absence of a \u003ca href=\"https://apnews.com/d79fdb57df9148f98ba42afff1958ffb\">Nobel Literature prize\u003c/a> , which has been won by 14 women, puts an even sharper focus on the gender gap in science prizes.\u003c/p>\n\u003cp>The Swedish Academy, which awards the literature prize, said it would not pick a winner this year after sex abuse allegations and financial crimes scandals rocked the secretive panel, sharply dividing its 18 members, who are appointed for life. Seven members quit or distanced themselves from academy. Its permanent secretary, Anders Olsson, said the academy wanted “to commit time to recovering public confidence.”\u003c/p>\n\u003cp>The academy plans to award both the 2018 prize and the 2019 prize next year — but even that is not guaranteed. The head of the Nobel Foundation, Lars Heikensten, has warned that if the Swedish Academy does not resolve its tarnished image another group could be chosen to select the literature prize each year.\u003c/p>\n\u003cp>Stung by criticism about the diversity gap between former prize winners, the Nobel Foundation has asked that the science awarding panels for 2019 ask nominators to consider their own biases in the thousands of letters they send to solicit Nobel nominations.\u003c/p>\n\u003cp>“I am eager to see more nominations for women so they can be considered,” said Goran Hansson, secretary-general of the Royal Swedish Academy of Sciences and vice chairman of the Nobel Foundation. “We have written to nominators asking them to make sure they do not miss women or people of other ethnicities or nationalities in their nominations. We hope this will make a difference for 2019.”\u003c/p>\n\u003cp>It’s not the first time that Nobel officials have sought diversity. In his 1895 will, prize founder Alfred Nobel wrote: “It is my express wish that in the awarding of the prizes no consideration shall be given to national affiliations of any kind, so that the most worthy shall receive the prize, whether he be Scandinavian or not.”\u003c/p>\n\u003cp>Even so, the prizes remained overwhelmingly white and male for most of their existence.\u003c/p>\n\u003cp>For the first 70 years, the peace prize skewed heavily toward Western white men, with just two of the 59 prizes awarded to individuals or institutions based outside Europe or North America. Only three of the winners in that period were female.\u003c/p>\n\u003cp>The 1973 peace prize shared by North Vietnam’s Le Duc Tho and American Henry Kissinger widened the horizons — since then more than half the Nobel Peace prizes have gone to African or Asian individuals or institutions.\u003c/p>\n\u003cp>Since 2000, six women have won the peace prize.\u003c/p>\n\u003cp>\u003c/p>\u003c/div>","attributes":{"named":{},"numeric":[]}},{"type":"component","content":"","name":"ad","attributes":{"named":{"label":"floatright"},"numeric":["floatright"]}},{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003c/p>\n\u003cp>After the medicine prize on Monday, the Royal Swedish Academy of Sciences will announce the Nobel in physics on Tuesday and in chemistry on Wednesday, while the Nobel Peace Prize will be awarded Friday by the Norwegian Nobel Committee. On Oct. 8, Sweden’s Central Bank announces the winner of the economics prize, given in honor of Alfred Nobel.\u003c/p>\n\u003cdiv id=\"div-gpt-ad-1470255291270-0\" class=\"ad-placeholder\">\n\u003cp> \u003c/p>\n\u003c/div>\n\n\u003c/div>\u003c/p>","attributes":{"named":{},"numeric":[]}}],"link":"/futureofyou/444697/nobel-prizes-grapple-with-widespread-gender-disparity","authors":["byline_futureofyou_444697"],"categories":["futureofyou_73"],"tags":["futureofyou_791","futureofyou_607"],"featImg":"futureofyou_444699","label":"source_futureofyou_444697"},"futureofyou_435777":{"type":"posts","id":"futureofyou_435777","meta":{"index":"posts_1591205157","site":"futureofyou","id":"435777","score":null,"sort":[1507100499000]},"guestAuthors":[],"slug":"how-messing-with-our-body-clocks-can-raise-alarms-with-health","title":"Keeping Internal Clocks Regular Sets Stage for Good Health","publishDate":1507100499,"format":"standard","headTitle":"KQED Future of You | KQED Science","labelTerm":{"site":"futureofyou"},"content":"\u003cp>Research that helped discover the clocks running in every cell in our bodies earned three scientists a Nobel Prize in medicine on Monday.\u003c/p>\n\u003caside class=\"pullquote alignright\">We humans are time-keeping machines.\u003c/aside>\n\u003cp>\"With exquisite precision, our inner clock adapts our physiology to the dramatically different phases of the day,\" the Nobel Prize committee \u003ca href=\"http://www.npr.org/sections/thetwo-way/2017/10/02/554993385/nobel-prize-in-medicine-is-awarded-to-3-americans-for-work-on-circadian-rhythm\">wrote\u003c/a> of the work of Jeffrey C. Hall, Michael Rosbash and Michael W. Young. \"The clock regulates critical functions such as behavior, hormone levels, sleep, body temperature and metabolism.\"\u003c/p>\n\u003cp>We humans are time-keeping machines. And it seems we need regular sleeping and eating schedules to keep all of our clocks in sync.\u003c/p>\n\u003cp>Studies show that if we mess with the body's natural sleep-wake cycle — say, by working an overnight shift, taking a trans-Aatlantic flight or staying up all night with a new baby or puppy — we pay the price.\u003c/p>\n\u003cp>Our blood pressure goes up, hunger hormones get thrown off and blood sugar control goes south.\u003c/p>\n\u003cp>[ad fullwidth]\u003c/p>\n\u003cp>[contextly_sidebar id=\"7S0R6t5jB019yBlneO6IBb620pV8FH0F\"]We can all recover from an occasional all-nighter, an episode of \u003ca href=\"http://www.npr.org/blogs/thesalt/2012/05/15/152690836/jetlagged-by-your-social-calendar-better-check-your-waistline\">jet lag\u003c/a> or short-term disruptions.\u003c/p>\n\u003cp>But over time, if living against the clock becomes a way of life, this may set the stage for weight gain and metabolic diseases such as Type 2 diabetes.\u003c/p>\n\u003cp>\"What happens is that you get a total de-synchronization of the clocks within us,\" explains \u003ca href=\"http://www.neurobiology.northwestern.edu/people/core-faculty/fred-turek.html\">Fred Turek\u003c/a>, a circadian scientist at Northwestern University. \"Which may be underlying the chronic diseases we face in our society today.\"\u003c/p>\n\u003cp>So consider what happens, for instance, if we eat late or in the middle of the night. The master clock — which is set by the light-dark cycle — is cuing all other clocks in the body that it's night. Time to rest.\u003c/p>\n\u003cp>\"The clock in the brain is sending signals saying: Do not eat, do not eat!\" says Turek.\u003c/p>\n\u003cp>But when we override this signal and eat anyway, the clock in the pancreas, for instance, has to start releasing insulin to deal with the meal. And, research suggests, this late-night munching may start to reset the clock in the organ. The result? Competing time cues.\u003c/p>\n\u003cp>\"The pancreas is listening to signals related to food intake. But that's out of sync with what the brain is telling it to do,\" says Turek. \"So if we're sending signals to those organs at the wrong time of day — such as eating at the wrong time of day — [we're] upsetting the balance.\"\u003c/p>\n\u003cp>And there's accumulating evidence that we may be more sensitive to these timing cues than scientists ever imagined.\u003c/p>\n\u003cp>Consider, for instance, the results of a weight-loss study that we \u003ca href=\"http://www.npr.org/blogs/thesalt/2013/01/30/170591028/to-maximize-weight-loss-eat-early-in-the-day-not-late\">reported\u003c/a> on, which was \u003ca href=\"http://www.nature.com/articles/ijo2012229.epdf?referrer_access_token=dfwcZDpYAoJZu6Z-jfDWKNRgN0jAjWel9jnR3ZoTv0OoXMYxeUF5K1SF8LoOyYhWHpTWbYAprLsgGQpZUO-8dRgCsqvc69Y6ybR2icWqKNZrh_6mGhPVx5UkksCfOoxHL20408_DDob5XOcvWupyp7UK9qL-EM1cBouacqb4ctvAQEttrbhdfb73szArvXfotICQ2OLQHwSxoMZuG_s0AKrTt1X14w0q94UPGaCHOdB-HeTw-VJC8ISkWpFd62jb&tracking_referrer=www.npr.org\">published\u003c/a> in 2013 in the \u003cem>International Journal of Obesity\u003c/em>. Researchers found that the timing of meals can influence how much weight people lose.\u003c/p>\n\u003cp>\"The finding that we had was that people who ate their main meal earlier in the day were much more successful at losing weight,\" says study author \u003ca href=\"https://sleep.med.harvard.edu/people/faculty/242/frank+a+j+l+scheer+phd\">Frank Scheer\u003c/a>, a Harvard neuroscientist who directs the \u003ca href=\"https://sleep.med.harvard.edu/research/labs/54/Medical+Chronobiology+Program+MCP+Research+on+Circadian+Rhythms+in+Health+and+Di\">Medical Chronobiology Program\u003c/a> at Brigham and Women's Hospital.\u003c/p>\n\u003cp>In fact, early eaters lost 25 percent more weight than later eaters — \"a surprisingly large difference,\" Scheer says. Another\u003ca href=\"http://www.ncbi.nlm.nih.gov/pubmed/23512957\"> study\u003c/a> found that eating a big breakfast was more conducive to weight loss, compared with a big dinner — adding to the evidence that the timing of meals is important.\u003c/p>\n\u003cp>Beyond weight management, there's evidence that the clocks in our bodies — and the timing of our sleeping, eating and activities — play multiple roles in helping us maintain good health. And different systems in the body are programmed to do different tasks at different times.\u003c/p>\n\u003cp>For instance, doctors have long known that the time of day you take a drug can influence its potency. \"If you take a drug at one time of day, it might be much more toxic than another time of day,\" Turek says. Part of this effect could be that the liver is better at detoxifying at certain times of day.\u003c/p>\n\u003cp>Turek says his hope is that, down the road, circadian science will be integrated into the practice of medicine.\u003c/p>\n\u003cp>\"We'd like to be in a position where we'd be able to monitor hundreds of different rhythms in your body and see if they're out of sync — and then try to normalize them,\" Turek says.\u003c/p>\n\u003cp>Whether — or how quickly — this may happen is hard to say. But what's clear is that the study of the biology of time is exploding.\u003c/p>\n\u003cp>\"What we're doing now in medicine is what Einstein did for physics,\" says Turek. \"He brought time to physics. We're bringing time to biology.\"\u003c/p>\n\u003cp>The irony, of course, is that this insight comes at a time when the demands of our 24/7 society mean more and more of us are overriding our internal clocks.\u003c/p>\n\u003cp>\u003c/p>\n\u003cp>\u003cem>A previous \u003c/em>\u003ca href=\"http://www.npr.org/sections/thesalt/2015/03/10/389596946/circadian-surprise-how-our-body-clocks-help-shape-our-waistlines\">\u003cem>version\u003c/em>\u003c/a>\u003cem> of this story was published in 2015. \u003c/em>\u003c/p>\n\u003cdiv class=\"fullattribution\">Copyright 2017 NPR. To see more, visit http://www.npr.org/.\u003cimg src=\"https://www.google-analytics.com/__utm.gif?utmac=UA-5828686-4&utmdt=How+Messing+With+Our+Body+Clocks+Can+Raise+Alarms+With+Health&utme=8(APIKey)9(MDAxOTAwOTE4MDEyMTkxMDAzNjczZDljZA004)\">\u003c/div>\n\n","blocks":[],"excerpt":"The scientists honored with a Nobel Prize in medicine helped discover that every cell in the body has its own clock. When we ignore those clocks, we increase the risk of weight gain and diabetes.","status":"publish","parent":0,"modified":1507058365,"stats":{"hasAudio":false,"hasVideo":false,"hasChartOrMap":false,"iframeSrcs":[],"hasGoogleForm":false,"hasGallery":false,"hasHearkenModule":false,"hasPolis":false,"paragraphCount":26,"wordCount":840},"headData":{"title":"Keeping Internal Clocks Regular Sets Stage for Good Health | KQED","description":"The scientists honored with a Nobel Prize in medicine helped discover that every cell in the body has its own clock. When we ignore those clocks, we increase the risk of weight gain and diabetes.","ogTitle":"","ogDescription":"","ogImgId":"","twTitle":"","twDescription":"","twImgId":"","schema":{"@context":"http://schema.org","@type":"Article","headline":"Keeping Internal Clocks Regular Sets Stage for Good Health","datePublished":"2017-10-04T07:01:39.000Z","dateModified":"2017-10-03T19:19:25.000Z","image":"https://cdn.kqed.org/wp-content/uploads/2020/02/KQED-OG-Image@1x.png"}},"disqusIdentifier":"435777 https://ww2.kqed.org/futureofyou/?p=435777","disqusUrl":"https://ww2.kqed.org/futureofyou/2017/10/04/how-messing-with-our-body-clocks-can-raise-alarms-with-health/","disqusTitle":"Keeping Internal Clocks Regular Sets Stage for Good Health","nprByline":"Allison Aubrey\u003cbr/>NPR Shots","nprImageAgency":"Katherine Streeter for NPR","nprStoryId":"555054483","nprApiLink":"http://api.npr.org/query?id=555054483&apiKey=MDAxOTAwOTE4MDEyMTkxMDAzNjczZDljZA004","nprHtmlLink":"http://www.npr.org/sections/health-shots/2017/10/02/555054483/how-messing-with-our-body-clocks-can-raise-alarms-with-health?ft=nprml&f=555054483","nprRetrievedStory":"1","nprPubDate":"Mon, 02 Oct 2017 15:57:00 -0400","nprStoryDate":"Mon, 02 Oct 2017 12:31:00 -0400","nprLastModifiedDate":"Mon, 02 Oct 2017 15:57:45 -0400","path":"/futureofyou/435777/how-messing-with-our-body-clocks-can-raise-alarms-with-health","audioTrackLength":null,"parsedContent":[{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003cp>Research that helped discover the clocks running in every cell in our bodies earned three scientists a Nobel Prize in medicine on Monday.\u003c/p>\n\u003caside class=\"pullquote alignright\">We humans are time-keeping machines.\u003c/aside>\n\u003cp>\"With exquisite precision, our inner clock adapts our physiology to the dramatically different phases of the day,\" the Nobel Prize committee \u003ca href=\"http://www.npr.org/sections/thetwo-way/2017/10/02/554993385/nobel-prize-in-medicine-is-awarded-to-3-americans-for-work-on-circadian-rhythm\">wrote\u003c/a> of the work of Jeffrey C. Hall, Michael Rosbash and Michael W. Young. \"The clock regulates critical functions such as behavior, hormone levels, sleep, body temperature and metabolism.\"\u003c/p>\n\u003cp>We humans are time-keeping machines. And it seems we need regular sleeping and eating schedules to keep all of our clocks in sync.\u003c/p>\n\u003cp>Studies show that if we mess with the body's natural sleep-wake cycle — say, by working an overnight shift, taking a trans-Aatlantic flight or staying up all night with a new baby or puppy — we pay the price.\u003c/p>\n\u003cp>Our blood pressure goes up, hunger hormones get thrown off and blood sugar control goes south.\u003c/p>\n\u003cp>\u003c/p>\u003c/div>","attributes":{"named":{},"numeric":[]}},{"type":"component","content":"","name":"ad","attributes":{"named":{"label":"fullwidth"},"numeric":["fullwidth"]}},{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003c/p>\n\u003cp>\u003c/p>\u003cp>\u003c/p>\u003cp>We can all recover from an occasional all-nighter, an episode of \u003ca href=\"http://www.npr.org/blogs/thesalt/2012/05/15/152690836/jetlagged-by-your-social-calendar-better-check-your-waistline\">jet lag\u003c/a> or short-term disruptions.\u003c/p>\n\u003cp>But over time, if living against the clock becomes a way of life, this may set the stage for weight gain and metabolic diseases such as Type 2 diabetes.\u003c/p>\n\u003cp>\"What happens is that you get a total de-synchronization of the clocks within us,\" explains \u003ca href=\"http://www.neurobiology.northwestern.edu/people/core-faculty/fred-turek.html\">Fred Turek\u003c/a>, a circadian scientist at Northwestern University. \"Which may be underlying the chronic diseases we face in our society today.\"\u003c/p>\n\u003cp>So consider what happens, for instance, if we eat late or in the middle of the night. The master clock — which is set by the light-dark cycle — is cuing all other clocks in the body that it's night. Time to rest.\u003c/p>\n\u003cp>\"The clock in the brain is sending signals saying: Do not eat, do not eat!\" says Turek.\u003c/p>\n\u003cp>But when we override this signal and eat anyway, the clock in the pancreas, for instance, has to start releasing insulin to deal with the meal. And, research suggests, this late-night munching may start to reset the clock in the organ. The result? Competing time cues.\u003c/p>\n\u003cp>\"The pancreas is listening to signals related to food intake. But that's out of sync with what the brain is telling it to do,\" says Turek. \"So if we're sending signals to those organs at the wrong time of day — such as eating at the wrong time of day — [we're] upsetting the balance.\"\u003c/p>\n\u003cp>And there's accumulating evidence that we may be more sensitive to these timing cues than scientists ever imagined.\u003c/p>\n\u003cp>Consider, for instance, the results of a weight-loss study that we \u003ca href=\"http://www.npr.org/blogs/thesalt/2013/01/30/170591028/to-maximize-weight-loss-eat-early-in-the-day-not-late\">reported\u003c/a> on, which was \u003ca href=\"http://www.nature.com/articles/ijo2012229.epdf?referrer_access_token=dfwcZDpYAoJZu6Z-jfDWKNRgN0jAjWel9jnR3ZoTv0OoXMYxeUF5K1SF8LoOyYhWHpTWbYAprLsgGQpZUO-8dRgCsqvc69Y6ybR2icWqKNZrh_6mGhPVx5UkksCfOoxHL20408_DDob5XOcvWupyp7UK9qL-EM1cBouacqb4ctvAQEttrbhdfb73szArvXfotICQ2OLQHwSxoMZuG_s0AKrTt1X14w0q94UPGaCHOdB-HeTw-VJC8ISkWpFd62jb&tracking_referrer=www.npr.org\">published\u003c/a> in 2013 in the \u003cem>International Journal of Obesity\u003c/em>. Researchers found that the timing of meals can influence how much weight people lose.\u003c/p>\n\u003cp>\"The finding that we had was that people who ate their main meal earlier in the day were much more successful at losing weight,\" says study author \u003ca href=\"https://sleep.med.harvard.edu/people/faculty/242/frank+a+j+l+scheer+phd\">Frank Scheer\u003c/a>, a Harvard neuroscientist who directs the \u003ca href=\"https://sleep.med.harvard.edu/research/labs/54/Medical+Chronobiology+Program+MCP+Research+on+Circadian+Rhythms+in+Health+and+Di\">Medical Chronobiology Program\u003c/a> at Brigham and Women's Hospital.\u003c/p>\n\u003cp>In fact, early eaters lost 25 percent more weight than later eaters — \"a surprisingly large difference,\" Scheer says. Another\u003ca href=\"http://www.ncbi.nlm.nih.gov/pubmed/23512957\"> study\u003c/a> found that eating a big breakfast was more conducive to weight loss, compared with a big dinner — adding to the evidence that the timing of meals is important.\u003c/p>\n\u003cp>Beyond weight management, there's evidence that the clocks in our bodies — and the timing of our sleeping, eating and activities — play multiple roles in helping us maintain good health. And different systems in the body are programmed to do different tasks at different times.\u003c/p>\n\u003cp>For instance, doctors have long known that the time of day you take a drug can influence its potency. \"If you take a drug at one time of day, it might be much more toxic than another time of day,\" Turek says. Part of this effect could be that the liver is better at detoxifying at certain times of day.\u003c/p>\n\u003cp>Turek says his hope is that, down the road, circadian science will be integrated into the practice of medicine.\u003c/p>\n\u003cp>\"We'd like to be in a position where we'd be able to monitor hundreds of different rhythms in your body and see if they're out of sync — and then try to normalize them,\" Turek says.\u003c/p>\n\u003cp>Whether — or how quickly — this may happen is hard to say. But what's clear is that the study of the biology of time is exploding.\u003c/p>\n\u003cp>\"What we're doing now in medicine is what Einstein did for physics,\" says Turek. \"He brought time to physics. We're bringing time to biology.\"\u003c/p>\n\u003cp>The irony, of course, is that this insight comes at a time when the demands of our 24/7 society mean more and more of us are overriding our internal clocks.\u003c/p>\n\u003cp>\u003c/p>\n\u003cp>\u003cem>A previous \u003c/em>\u003ca href=\"http://www.npr.org/sections/thesalt/2015/03/10/389596946/circadian-surprise-how-our-body-clocks-help-shape-our-waistlines\">\u003cem>version\u003c/em>\u003c/a>\u003cem> of this story was published in 2015. \u003c/em>\u003c/p>\n\u003cdiv class=\"fullattribution\">Copyright 2017 NPR. To see more, visit http://www.npr.org/.\u003cimg src=\"https://www.google-analytics.com/__utm.gif?utmac=UA-5828686-4&utmdt=How+Messing+With+Our+Body+Clocks+Can+Raise+Alarms+With+Health&utme=8(APIKey)9(MDAxOTAwOTE4MDEyMTkxMDAzNjczZDljZA004)\">\u003c/div>\n\n\u003c/div>\u003c/p>","attributes":{"named":{},"numeric":[]}}],"link":"/futureofyou/435777/how-messing-with-our-body-clocks-can-raise-alarms-with-health","authors":["byline_futureofyou_435777"],"categories":["futureofyou_1"],"tags":["futureofyou_607","futureofyou_326"],"featImg":"futureofyou_435778","label":"futureofyou"}},"programsReducer":{"possible":{"id":"possible","title":"Possible","info":"Possible is hosted by entrepreneur Reid Hoffman and writer Aria Finger. Together in Possible, Hoffman and Finger lead enlightening discussions about building a brighter collective future. The show features interviews with visionary guests like Trevor Noah, Sam Altman and Janette Sadik-Khan. Possible paints an optimistic portrait of the world we can create through science, policy, business, art and our shared humanity. It asks: What if everything goes right for once? How can we get there? Each episode also includes a short fiction story generated by advanced AI GPT-4, serving as a thought-provoking springboard to speculate how humanity could leverage technology for good.","airtime":"SUN 2pm","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/Possible-Podcast-Tile-360x360-1.jpg","officialWebsiteLink":"https://www.possible.fm/","meta":{"site":"news","source":"Possible"},"link":"/radio/program/possible","subscribe":{"apple":"https://podcasts.apple.com/us/podcast/possible/id1677184070","spotify":"https://open.spotify.com/show/730YpdUSNlMyPQwNnyjp4k"}},"1a":{"id":"1a","title":"1A","info":"1A is home to the national conversation. 1A brings on great guests and frames the best debate in ways that make you think, share and engage.","airtime":"MON-THU 11pm-12am","imageSrc":"https://ww2.kqed.org/radio/wp-content/uploads/sites/50/2018/04/1a.jpg","officialWebsiteLink":"https://the1a.org/","meta":{"site":"news","source":"npr"},"link":"/radio/program/1a","subscribe":{"npr":"https://rpb3r.app.goo.gl/RBrW","apple":"https://itunes.apple.com/WebObjects/MZStore.woa/wa/viewPodcast?s=143441&mt=2&id=1188724250&at=11l79Y&ct=nprdirectory","tuneIn":"https://tunein.com/radio/1A-p947376/","rss":"https://feeds.npr.org/510316/podcast.xml"}},"all-things-considered":{"id":"all-things-considered","title":"All Things Considered","info":"Every weekday, \u003cem>All Things Considered\u003c/em> hosts Robert Siegel, Audie Cornish, Ari Shapiro, and Kelly McEvers present the program's trademark mix of news, interviews, commentaries, reviews, and offbeat features. Michel Martin hosts on the weekends.","airtime":"MON-FRI 1pm-2pm, 4:30pm-6:30pm\u003cbr />SAT-SUN 5pm-6pm","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/All-Things-Considered-Podcast-Tile-360x360-1.jpg","officialWebsiteLink":"https://www.npr.org/programs/all-things-considered/","meta":{"site":"news","source":"npr"},"link":"/radio/program/all-things-considered"},"american-suburb-podcast":{"id":"american-suburb-podcast","title":"American Suburb: The Podcast","tagline":"The flip side of gentrification, told through one town","info":"Gentrification is changing cities across America, forcing people from neighborhoods they have long called home. Call them the displaced. Now those priced out of the Bay Area are looking for a better life in an unlikely place. American Suburb follows this migration to one California town along the Delta, 45 miles from San Francisco. But is this once sleepy suburb ready for them?","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/American-Suburb-Podcast-Tile-703x703-1.jpg","officialWebsiteLink":"/news/series/american-suburb-podcast","meta":{"site":"news","source":"kqed","order":"13"},"link":"/news/series/american-suburb-podcast/","subscribe":{"npr":"https://rpb3r.app.goo.gl/RBrW","apple":"https://itunes.apple.com/WebObjects/MZStore.woa/wa/viewPodcast?mt=2&id=1287748328","tuneIn":"https://tunein.com/radio/American-Suburb-p1086805/","rss":"https://ww2.kqed.org/news/series/american-suburb-podcast/feed/podcast","google":"https://podcasts.google.com/feed/aHR0cHM6Ly9mZWVkcy5tZWdhcGhvbmUuZm0vS1FJTkMzMDExODgxNjA5"}},"baycurious":{"id":"baycurious","title":"Bay Curious","tagline":"Exploring the Bay Area, one question at a time","info":"KQED’s new podcast, Bay Curious, gets to the bottom of the mysteries — both profound and peculiar — that give the Bay Area its unique identity. And we’ll do it with your help! You ask the questions. You decide what Bay Curious investigates. And you join us on the journey to find the answers.","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/Bay-Curious-Podcast-Tile-703x703-1.jpg","imageAlt":"\"KQED Bay Curious","officialWebsiteLink":"/news/series/baycurious","meta":{"site":"news","source":"kqed","order":"4"},"link":"/podcasts/baycurious","subscribe":{"apple":"https://podcasts.apple.com/us/podcast/bay-curious/id1172473406","npr":"https://www.npr.org/podcasts/500557090/bay-curious","rss":"https://ww2.kqed.org/news/category/bay-curious-podcast/feed/podcast","google":"https://podcasts.google.com/feed/aHR0cHM6Ly93dzIua3FlZC5vcmcvbmV3cy9jYXRlZ29yeS9iYXktY3VyaW91cy1wb2RjYXN0L2ZlZWQvcG9kY2FzdA","stitcher":"https://www.stitcher.com/podcast/kqed/bay-curious","spotify":"https://open.spotify.com/show/6O76IdmhixfijmhTZLIJ8k"}},"bbc-world-service":{"id":"bbc-world-service","title":"BBC World Service","info":"The day's top stories from BBC News compiled twice daily in the week, once at weekends.","airtime":"MON-FRI 9pm-10pm, TUE-FRI 1am-2am","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/BBC-World-Service-Podcast-Tile-360x360-1.jpg","officialWebsiteLink":"https://www.bbc.co.uk/sounds/play/live:bbc_world_service","meta":{"site":"news","source":"BBC World Service"},"link":"/radio/program/bbc-world-service","subscribe":{"apple":"https://itunes.apple.com/us/podcast/global-news-podcast/id135067274?mt=2","tuneIn":"https://tunein.com/radio/BBC-World-Service-p455581/","rss":"https://podcasts.files.bbci.co.uk/p02nq0gn.rss"}},"code-switch-life-kit":{"id":"code-switch-life-kit","title":"Code Switch / Life Kit","info":"\u003cem>Code Switch\u003c/em>, which listeners will hear in the first part of the hour, has fearless and much-needed conversations about race. Hosted by journalists of color, the show tackles the subject of race head-on, exploring how it impacts every part of society — from politics and pop culture to history, sports and more.\u003cbr />\u003cbr />\u003cem>Life Kit\u003c/em>, which will be in the second part of the hour, guides you through spaces and feelings no one prepares you for — from finances to mental health, from workplace microaggressions to imposter syndrome, from relationships to parenting. The show features experts with real world experience and shares their knowledge. Because everyone needs a little help being human.\u003cbr />\u003cbr />\u003ca href=\"https://www.npr.org/podcasts/510312/codeswitch\">\u003cem>Code Switch\u003c/em> offical site and podcast\u003c/a>\u003cbr />\u003ca href=\"https://www.npr.org/lifekit\">\u003cem>Life Kit\u003c/em> offical site and podcast\u003c/a>\u003cbr />","airtime":"SUN 9pm-10pm","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/Code-Switch-Life-Kit-Podcast-Tile-360x360-1.jpg","meta":{"site":"radio","source":"npr"},"link":"/radio/program/code-switch-life-kit","subscribe":{"apple":"https://podcasts.apple.com/podcast/1112190608?mt=2&at=11l79Y&ct=nprdirectory","google":"https://podcasts.google.com/feed/aHR0cHM6Ly93d3cubnByLm9yZy9yc3MvcG9kY2FzdC5waHA_aWQ9NTEwMzEy","spotify":"https://open.spotify.com/show/3bExJ9JQpkwNhoHvaIIuyV","rss":"https://feeds.npr.org/510312/podcast.xml"}},"commonwealth-club":{"id":"commonwealth-club","title":"Commonwealth Club of California Podcast","info":"The Commonwealth Club of California is the nation's oldest and largest public affairs forum. 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