This Digital Pill Wants To Make Following Your Prescription Easier
Approval of Cheaper Hepatitis C Drug Will Likely Expand Treatment
New Hepatitis C Drug Could Bring Down Cost of Treatment
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A new clinical study is underway at 16 health centers around the country to see if a pill with an ingestible sensor can improve medication adherence rates for \u003ca href=\"https://www.cdc.gov/hepatitis/hcv/cfaq.htm\" target=\"_blank\" rel=\"noopener\">Hepatitis C\u003c/a> drugs.\u003c/p>\n\u003cp>\u003ca href=\"https://www.proteus.com/\" target=\"_blank\" rel=\"noopener\">Proteus Digital Health\u003c/a>, the inventor of this so-called digital pill, is part of an emerging field of medicine and one of a handful of companies designing these high-tech pills.\u003c/p>\n\u003cp>While medication adherence is an issue for everyone, it can be especially difficult for patients with mental health and substance abuse conditions to rigorously follow their prescriptions.\u003c/p>\n\u003cp>And the latter is a significant factor in the spread of Hepatitis C. Intravenous drug use, particularly opioids, has fueled a \u003ca href=\"https://www.cdc.gov/nchhstp/newsroom/2017/Hepatitis-Surveillance-Press-Release.html\">spike in\u003c/a> Hepatitis C infections in recent years.\u003c/p>\n\u003cp>[ad fullwidth]\u003c/p>\n\u003cp>On Wednesday’s PBS NewsHour, I explore how a new wave of Hepatitis C drugs, known as direct-acting antivirals, can cure the disease 95 percent of time when used as prescribed. But insurance providers have limited their payouts and the access for direct-acting antivirals, due to the drugs’ expensive price tag.\u003c/p>\n\u003cp>[youtube https://www.youtube.com/watch?v=3DN2gI87R3Q?feature=oembed]\u003c/p>\n\u003cp>David Wyles, head of infectious diseases at \u003ca href=\"https://www.denverhealth.org/\" target=\"_blank\" rel=\"noopener\">Denver Health\u003c/a> where the digital pill is being trialed, said the information gathered from the study may help \u003ca href=\"https://www.chlpi.org/chlpi-nvhr-launch-interactive-report-card-project-grading-52-medicaid-programs-discriminatory-hepatitis-c-treatment-restrictions/\" target=\"_blank\" rel=\"noopener\">convince insurers to expand access \u003c/a>to the new but more expensive Hepatitis C drugs. \u003ca href=\"https://www.denverhealth.org/\" target=\"_blank\" rel=\"noopener\">Denver Health\u003c/a> has 18 voluntary patients enrolled in the trial and is one of the largest study sites. The Colorado Department of Health estimates about \u003ca href=\"https://drive.google.com/file/d/0B0tmPQ67k3NVQjJXSFRGajdWUEE/view\" target=\"_blank\" rel=\"noopener\">70,000\u003c/a> people in the state carry Hepatitis C, and Denver Health cares for many of them.\u003c/p>\n\u003cp>“Insurance payers have imposed restrictions, not necessarily based on medical or scientific facts,” Wyles said. “This is a population that some will look at and say, ‘They won’t take their medications, why would we want to treat them?’ Potentially this study is something to refute that if we can show adherence rates are good.”[contextly_sidebar id=\"64LqO8WUg7X2FUJe9uqsRXqMVyuUE8BQ\"]\u003c/p>\n\u003cp>Proteus’ digital pill consists of the prescription medication with a tiny, FDA-approved ingestible sensor, packed inside a gel capsule. Once swallowed, minerals in the sensor react when they hit the acids in the stomach and create a tiny electronic signal. A band-aid-like patch, worn on the skin of the torso, captures this signal and relays it to an app on a smartphone or tablet.\u003c/p>\n\u003cp>Patients share the data with their doctors but also control who else has access. Their doctors can then monitor when and how many pills have been taken.\u003c/p>\n\u003cp>“If the patient misses a dose or a couple of doses, you can set up an alert in the program to send you an email. You can contact them and hopefully intervene right away,” David Wyles said. “Without the technology, you may not know anything until your next visit, which could be a month later, and then it’s too late to do anything.”\u003c/p>\n\u003cp>Yet the new technology raises questions about patient privacy. \u003ca href=\"https://psychnews.psychiatryonline.org/doi/full/10.1176/appi.pn.2017.pp12a2\" target=\"_blank\" rel=\"noopener\">Some doctors in the mental health community\u003c/a> expressed concerns last year about patient trust and misuse of data when the \u003ca href=\"https://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm584933.htm\" target=\"_blank\" rel=\"noopener\">FDA approved\u003c/a> Proteus Digital Health’s sensors to be embedded in the antipsychotic drug \u003ca href=\"https://www.proteus.com/press-releases/otsuka-and-proteus-announce-the-first-us-fda-approval-of-a-digital-medicine-system-abilify-mycite/\" target=\"_blank\" rel=\"noopener\">Abilify.[contextly_sidebar id=\"BuXdE0rwLJ9KNHT80EszuM4r2ocN7n84\"]\u003c/a>\u003c/p>\n\u003cp>“In an era in which even the National Security Agency gets hacked, there are obvious concerns about patient privacy with a technology that communicates personal medical information,” Paul Appelbaum, director of the division of Law, Ethics, and Psychiatry at Columbia University, \u003ca href=\"https://psychnews.psychiatryonline.org/doi/full/10.1176/appi.pn.2017.pp12a2\" target=\"_blank\" rel=\"noopener\">told Psychiatric News\u003c/a>. “The potential for this technology to be misused by judges and probation officers who may require offenders to use pills with sensors, and then respond punitively to the most trivial failure to adhere to the treatment regimen, is real.”\u003c/p>\n\u003cp>Dr. George Savage, chief medical officer for Proteus Digital Health, said his company is adamant about patients controlling their own data: “The patient owns their own data and decides who to share it with beyond their medical team. We don’t sell data and never will.”\u003c/p>\n\u003cp>Nine health systems across the U.S. have used the technology so far for conditions like diabetes, heart failure, and hypertension. Proteus Digital Health is also testing the digital pills with oncology and HIV drugs, and on patients using opioids for pain relief. Dr. Savage said adherence rates with the digital pills have been shown to be high.\u003c/p>\n\u003cp>‘When we provide feedback to the patient, adherence is about 87 percent,” Savage said. “When we add in someone following up with a patient, like a doctor, adherence is 96 percent. Near perfection.”\u003c/p>\n\u003cp>\u003c/p>\n\u003cp>\u003cem>Editor’s note: This post has been updated to clarify that the signal is only sent once when the pill reaches the stomach acid and that the related patch is worn on the torso.\u003c/em>\u003c/p>\n\n","blocks":[],"excerpt":"A new clinical study is underway at 16 health centers around the country to see if a pill with an ingestible sensor can improve medication adherence rates for hepatitis C drugs. ","status":"publish","parent":0,"modified":1527615917,"stats":{"hasAudio":false,"hasVideo":true,"hasChartOrMap":false,"iframeSrcs":[],"hasGoogleForm":false,"hasGallery":false,"hasHearkenModule":false,"hasPolis":false,"paragraphCount":20,"wordCount":900},"headData":{"title":"This Digital Pill Wants To Make Following Your Prescription Easier | KQED","description":"A new clinical study is underway at 16 health centers around the country to see if a pill with an ingestible sensor can improve medication adherence rates for hepatitis C drugs. ","ogTitle":"","ogDescription":"","ogImgId":"","twTitle":"","twDescription":"","twImgId":"","schema":{"@context":"http://schema.org","@type":"Article","headline":"This Digital Pill Wants To Make Following Your Prescription Easier","datePublished":"2018-05-29T17:43:50.000Z","dateModified":"2018-05-29T17:45:17.000Z","image":"https://cdn.kqed.org/wp-content/uploads/2020/02/KQED-OG-Image@1x.png"}},"disqusIdentifier":"442141 https://ww2.kqed.org/futureofyou/?p=442141","disqusUrl":"https://ww2.kqed.org/futureofyou/2018/05/29/this-digital-pill-wants-to-make-following-your-prescription-easier/","disqusTitle":"This Digital Pill Wants To Make Following Your Prescription Easier","source":"Health","nprByline":"Cat Wise, PBS Health NewsHour","path":"/futureofyou/442141/this-digital-pill-wants-to-make-following-your-prescription-easier","audioTrackLength":null,"parsedContent":[{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003cp>Doctors \u003ca href=\"http://annals.org/aim/fullarticle/1357338/interventions-improve-adherence-self-administered-medications-chronic-diseases-united-states\" target=\"_blank\" rel=\"noopener\">estimate\u003c/a> about half of all medications for chronic conditions are not taken as prescribed, resulting in $100 billion to $289 billion in preventable health care costs and more than 100,000 deaths every year in the U.S. \u003ca href=\"https://www.ncbi.nlm.nih.gov/pubmed/22510235\" target=\"_blank\" rel=\"noopener\">A majority of adults\u003c/a> say they struggle with remembering to take their prescriptions.\u003c/p>\u003cp>\u003c/p>\u003cp>\u003c/p>\n\u003cp>Now, as with many other seemingly intractable challenges, technology has been enlisted to help. A new clinical study is underway at 16 health centers around the country to see if a pill with an ingestible sensor can improve medication adherence rates for \u003ca href=\"https://www.cdc.gov/hepatitis/hcv/cfaq.htm\" target=\"_blank\" rel=\"noopener\">Hepatitis C\u003c/a> drugs.\u003c/p>\n\u003cp>\u003ca href=\"https://www.proteus.com/\" target=\"_blank\" rel=\"noopener\">Proteus Digital Health\u003c/a>, the inventor of this so-called digital pill, is part of an emerging field of medicine and one of a handful of companies designing these high-tech pills.\u003c/p>\n\u003cp>While medication adherence is an issue for everyone, it can be especially difficult for patients with mental health and substance abuse conditions to rigorously follow their prescriptions.\u003c/p>\n\u003cp>And the latter is a significant factor in the spread of Hepatitis C. Intravenous drug use, particularly opioids, has fueled a \u003ca href=\"https://www.cdc.gov/nchhstp/newsroom/2017/Hepatitis-Surveillance-Press-Release.html\">spike in\u003c/a> Hepatitis C infections in recent years.\u003c/p>\n\u003cp>\u003c/p>\u003c/div>","attributes":{"named":{},"numeric":[]}},{"type":"component","content":"","name":"ad","attributes":{"named":{"label":"fullwidth"},"numeric":["fullwidth"]}},{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003c/p>\n\u003cp>On Wednesday’s PBS NewsHour, I explore how a new wave of Hepatitis C drugs, known as direct-acting antivirals, can cure the disease 95 percent of time when used as prescribed. But insurance providers have limited their payouts and the access for direct-acting antivirals, due to the drugs’ expensive price tag.\u003c/p>\n\u003cp>\u003c/p>\u003cp>\u003cspan class='utils-parseShortcode-shortcodes-__youtubeShortcode__embedYoutube'>\n \u003cspan class='utils-parseShortcode-shortcodes-__youtubeShortcode__embedYoutubeInside'>\n \u003ciframe\n loading='lazy'\n class='utils-parseShortcode-shortcodes-__youtubeShortcode__youtubePlayer'\n type='text/html'\n src='//www.youtube.com/embed/3DN2gI87R3Q?feature=oembed'\n title='//www.youtube.com/embed/3DN2gI87R3Q?feature=oembed'\n allowfullscreen='true'\n style='border:0;'>\u003c/iframe>\n \u003c/span>\n \u003c/span>\u003c/p>\u003cp>\u003c/p>\n\u003cp>David Wyles, head of infectious diseases at \u003ca href=\"https://www.denverhealth.org/\" target=\"_blank\" rel=\"noopener\">Denver Health\u003c/a> where the digital pill is being trialed, said the information gathered from the study may help \u003ca href=\"https://www.chlpi.org/chlpi-nvhr-launch-interactive-report-card-project-grading-52-medicaid-programs-discriminatory-hepatitis-c-treatment-restrictions/\" target=\"_blank\" rel=\"noopener\">convince insurers to expand access \u003c/a>to the new but more expensive Hepatitis C drugs. \u003ca href=\"https://www.denverhealth.org/\" target=\"_blank\" rel=\"noopener\">Denver Health\u003c/a> has 18 voluntary patients enrolled in the trial and is one of the largest study sites. The Colorado Department of Health estimates about \u003ca href=\"https://drive.google.com/file/d/0B0tmPQ67k3NVQjJXSFRGajdWUEE/view\" target=\"_blank\" rel=\"noopener\">70,000\u003c/a> people in the state carry Hepatitis C, and Denver Health cares for many of them.\u003c/p>\n\u003cp>“Insurance payers have imposed restrictions, not necessarily based on medical or scientific facts,” Wyles said. “This is a population that some will look at and say, ‘They won’t take their medications, why would we want to treat them?’ Potentially this study is something to refute that if we can show adherence rates are good.”\u003c/p>\u003cp>\u003c/p>\u003cp>\u003c/p>\n\u003cp>Proteus’ digital pill consists of the prescription medication with a tiny, FDA-approved ingestible sensor, packed inside a gel capsule. Once swallowed, minerals in the sensor react when they hit the acids in the stomach and create a tiny electronic signal. A band-aid-like patch, worn on the skin of the torso, captures this signal and relays it to an app on a smartphone or tablet.\u003c/p>\n\u003cp>Patients share the data with their doctors but also control who else has access. Their doctors can then monitor when and how many pills have been taken.\u003c/p>\n\u003cp>“If the patient misses a dose or a couple of doses, you can set up an alert in the program to send you an email. You can contact them and hopefully intervene right away,” David Wyles said. “Without the technology, you may not know anything until your next visit, which could be a month later, and then it’s too late to do anything.”\u003c/p>\n\u003cp>Yet the new technology raises questions about patient privacy. \u003ca href=\"https://psychnews.psychiatryonline.org/doi/full/10.1176/appi.pn.2017.pp12a2\" target=\"_blank\" rel=\"noopener\">Some doctors in the mental health community\u003c/a> expressed concerns last year about patient trust and misuse of data when the \u003ca href=\"https://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm584933.htm\" target=\"_blank\" rel=\"noopener\">FDA approved\u003c/a> Proteus Digital Health’s sensors to be embedded in the antipsychotic drug \u003ca href=\"https://www.proteus.com/press-releases/otsuka-and-proteus-announce-the-first-us-fda-approval-of-a-digital-medicine-system-abilify-mycite/\" target=\"_blank\" rel=\"noopener\">Abilify.\u003c/p>\u003cp>\u003c/p>\u003cp>\u003c/a>\u003c/p>\n\u003cp>“In an era in which even the National Security Agency gets hacked, there are obvious concerns about patient privacy with a technology that communicates personal medical information,” Paul Appelbaum, director of the division of Law, Ethics, and Psychiatry at Columbia University, \u003ca href=\"https://psychnews.psychiatryonline.org/doi/full/10.1176/appi.pn.2017.pp12a2\" target=\"_blank\" rel=\"noopener\">told Psychiatric News\u003c/a>. “The potential for this technology to be misused by judges and probation officers who may require offenders to use pills with sensors, and then respond punitively to the most trivial failure to adhere to the treatment regimen, is real.”\u003c/p>\n\u003cp>Dr. George Savage, chief medical officer for Proteus Digital Health, said his company is adamant about patients controlling their own data: “The patient owns their own data and decides who to share it with beyond their medical team. We don’t sell data and never will.”\u003c/p>\n\u003cp>Nine health systems across the U.S. have used the technology so far for conditions like diabetes, heart failure, and hypertension. Proteus Digital Health is also testing the digital pills with oncology and HIV drugs, and on patients using opioids for pain relief. Dr. Savage said adherence rates with the digital pills have been shown to be high.\u003c/p>\n\u003cp>‘When we provide feedback to the patient, adherence is about 87 percent,” Savage said. “When we add in someone following up with a patient, like a doctor, adherence is 96 percent. Near perfection.”\u003c/p>\n\u003cp>\u003c/p>\n\u003cp>\u003cem>Editor’s note: This post has been updated to clarify that the signal is only sent once when the pill reaches the stomach acid and that the related patch is worn on the torso.\u003c/em>\u003c/p>\n\n\u003c/div>\u003c/p>","attributes":{"named":{},"numeric":[]}}],"link":"/futureofyou/442141/this-digital-pill-wants-to-make-following-your-prescription-easier","authors":["byline_futureofyou_442141"],"categories":["futureofyou_1060","futureofyou_1","futureofyou_73"],"tags":["futureofyou_26","futureofyou_736","futureofyou_1056","futureofyou_35"],"collections":["futureofyou_1093","futureofyou_1097"],"featImg":"futureofyou_442144","label":"source_futureofyou_442141"},"futureofyou_436058":{"type":"posts","id":"futureofyou_436058","meta":{"index":"posts_1591205157","site":"futureofyou","id":"436058","score":null,"sort":[1509743720000]},"guestAuthors":[],"slug":"approval-of-cheaper-hepatitis-c-drug-will-likely-expand-treatment","title":"Approval of Cheaper Hepatitis C Drug Will Likely Expand Treatment","publishDate":1509743720,"format":"standard","headTitle":"KQED Future of You | KQED Science","labelTerm":{"site":"futureofyou"},"content":"\u003cp>Valerie Green is still waiting to be cured.\u003c/p>\n\u003cp>The Delaware resident was diagnosed with hepatitis C more than two years ago, but she doesn't qualify yet for the Medicaid program's criteria for treatment with a new class of highly effective but pricey drugs.\u003c/p>\n\u003cp>The recent \u003ca href=\"https://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm570038.htm\">approval of a less expensive drug\u003c/a> that generally cures hepatitis C in just eight weeks may make it easier for more insurers and correctional facilities to expand treatment.\u003c/p>\n\u003cp>The drug, \u003ca href=\"https://www.mavyret.com/\">Mavyret\u003c/a>, is the first to be approved by the Food and Drug Administration that can cure all six genetic types of hepatitis C in about two months in patients who haven't previously been treated. Other approved drugs generally require 12 weeks to treat the disease and often aren't effective for all types of hepatitis C.\u003c/p>\n\u003cp>In addition, Mavyret's price tag of $26,400 for a course of treatment is significantly below that of other hepatitis C drugs whose sticker price ranges from about $55,000 to $95,000 to beat the disease. Patients and \u003ca href=\"https://www.macpac.gov/wp-content/uploads/2017/03/High-Cost-HCV-Drugs-in-Medicaid-Final-Report.pdf\">insurers often pay less\u003c/a>, however, through negotiated insurance discounts and rebates.\u003c/p>\n\u003cp>[ad fullwidth]\u003c/p>\n\u003cp>\"It certainly stands to reason that the continual march downward on cost would lead to continual opening up of criteria,\" says \u003ca href=\"http://medicaiddirectors.org/about/staff/\">Matt Salo\u003c/a>, executive director of the National Association of Medicaid Directors.\u003c/p>\n\u003cp>Hepatitis C \u003ca href=\"https://www.cdc.gov/hepatitis/hcv/cfaq.htm#cFAQ13\">is a viral liver infection\u003c/a> spread through blood that affects an estimated 3.5 million people in the United States. It can take years to cause problems. Many baby boomers who contracted it decades ago before blood was screened for the virus don't realize they have it until they develop liver disease. In addition, the growing heroin epidemic is adding to the problem as people become infected by \u003ca href=\"http://www.npr.org/sections/health-shots/2017/08/29/547054395/syringe-exchange-program-aims-to-slow-hepatitis-c-infections-in-alaska\">sharing contaminated needles\u003c/a>.\u003c/p>\n\u003cp>\"Direct-acting antiviral\" therapies like Harvoni, a once-a-day pill introduced in 2014 that generally cured hepatitis C in 12 weeks, are \u003ca href=\"http://www.cochrane.org/CD012143/LIVER_direct-acting-antivirals-chronic-hepatitis-c\">much more effective\u003c/a> than earlier treatments that required weekly interferon injections and multiple daily pills for nearly a year. But the newer regimens came at a price: $94,500, in Harvoni's case.\u003c/p>\n\u003cp>State Medicaid programs, which cover a high proportion of people with hepatitis C, \u003ca href=\"http://www.npr.org/sections/health-shots/2015/12/27/460086615/states-deny-pricey-hepatitis-c-drugs-to-most-medicaid-patients\">balked at the high prices\u003c/a>, even with the 23 percent drug discount the programs typically receive. Many threw up roadblocks to limit drug approval until the disease was advanced. Some required people to be drug- and alcohol-free for six months or more before treatment would be approved.\u003c/p>\n\u003cp>Those moves prompted advocates to push for better access, in some cases \u003ca href=\"https://khn.org/news/medicaid-private-insurers-begin-to-lift-curbs-on-pricey-hepatitis-c-drugs/\">filing suit\u003c/a> to force the programs to cover more people.\u003c/p>\n\u003cp>Faced with a lawsuit in Delaware, the state Medicaid program began loosening up treatment criteria this year, and in January will begin approving enrollees \u003ca href=\"https://www.chlpi.org/wp-content/uploads/2016/06/DMMA-Prior-Authorization-Policy.pdf\">regardless of the severity\u003c/a> of their disease.\u003c/p>\n\u003cp>The state joins more than a dozen others that no longer (or never did) restrict hepatitis C treatment based on disease severity, says \u003ca href=\"http://hls.harvard.edu/faculty/directory/11694/Costello\">Kevin Costello\u003c/a>, director of litigation at Harvard Law School's Center for Health Law and Policy Innovation, which has been a \u003ca href=\"https://www.chlpi.org/in-face-of-class-action-lawsuit-delaware-medicaid-removes-unlawful-restrictions-to-the-cure-for-the-hepatitis-c-virus/\">key player in litigation\u003c/a> in Delaware and other states.\u003c/p>\n\u003cp>It can't happen soon enough, says Green. She is 58 and believes she contracted the disease 31 years ago when she suffered complications during childbirth and required a blood transfusion. Although her liver isn't damaged, Green says, she has suffered with abdominal and joint pain, weight loss and fatigue for decades – all \u003ca href=\"https://www.cdc.gov/hepatitis/hcv/cfaq.htm#cFAQ41\">symptoms\u003c/a> her doctors attribute to the hepatitis C virus.\u003c/p>\n\u003cp>\"It's been a difficult fight for us Medicaid patients,\" she says.\u003c/p>\n\u003cp>People who are incarcerated face an even tougher battle to get treatment for hepatitis C. A recent study of state prisoners suggested that roughly \u003ca href=\"https://www.ncbi.nlm.nih.gov/pubmed/27702964\">17 percent of prisoners are infected\u003c/a> with hepatitis C, compared with about 1 percent of the general population.\u003c/p>\n\u003cp>Prisons have a duty not to be deliberately indifferent to the medical needs of incarcerated people. Prisons don't get the price discounts that the Medicaid programs have, and their budgets are fixed.\u003c/p>\n\u003cp>\"Administrators have to make do with what is there,\" says \u003ca href=\"https://sph.emory.edu/faculty/profile/#!aspauld\">Dr. Anne Spaulding\u003c/a>, an epidemiologist and associate professor at Emory University's public health school, who has worked as a medical director in corrections and published research on hepatitis C among prisoners.\u003c/p>\n\u003cp>Lawyers in a handful of states are pursuing class action lawsuits to force prisons to provide hepatitis C treatment. Mavyret may make a difference, says \u003ca href=\"https://www.law.upenn.edu/cf/faculty/drudovsk/\">David Rudovsky\u003c/a>, a civil rights lawyer who's litigating a class action lawsuit against the Pennsylvania Department of Corrections.\u003c/p>\n\u003cp>\"Everyone recognizes that it's going to make it easier to cover people,\" he says.\u003c/p>\n\u003cp>Coverage for drugs that treat hepatitis C is typically less problematic for people who have private insurance (though some obstacles remain). For example, Mavyret is one of seven hepatitis C drugs that are included in the 2018 \u003ca href=\"http://lab.express-scripts.com/lab/insights/drug-options/2018-national-preferred-formulary\">national preferred formulary\u003c/a> by Express Scripts, which manages the pharmacy benefits for 83 million people.\u003c/p>\n\u003cp>\"The benefit to patients and payers is the additional competition, which brings down costs across the class, thus resulting in greater access and affordability,\" says \u003ca href=\"http://lab.express-scripts.com/about/media-inquiries\">Jennifer Luddy\u003c/a>, director of corporate communications at Express Scripts.\u003c/p>\n\u003cp>\u003c/p>\n\u003cp>\u003cem>Kaiser Health News is an editorially independent news service that is part of the nonpartisan Henry J. Kaiser Family Foundation. Follow Michelle Andrews on Twitter: \u003c/em>\u003ca href=\"https://twitter.com/mandrews110\">@mandrews110\u003c/a>.\u003c/p>\n\u003cdiv class=\"fullattribution\">Copyright 2017 Kaiser Health News. To see more, visit \u003ca href=\"http://www.kaiserhealthnews.org/\">Kaiser Health News\u003c/a>.\u003cimg src=\"https://www.google-analytics.com/__utm.gif?utmac=UA-5828686-4&utmdt=FDA%27s+Approval+Of+A+Cheaper+Drug+For+Hepatitis+C+Will+Likely+Expand+Treatment&utme=8(APIKey)9(MDAxOTAwOTE4MDEyMTkxMDAzNjczZDljZA004)\">\u003c/div>\n\n","blocks":[],"excerpt":"Mavyret, recently approved by the Food And Drug Administration, can cure hepatitis C in eight weeks, at a cost of $26,400. Though still expensive, that's well below the price of other options.","status":"publish","parent":0,"modified":1509743720,"stats":{"hasAudio":false,"hasVideo":false,"hasChartOrMap":false,"iframeSrcs":[],"hasGoogleForm":false,"hasGallery":false,"hasHearkenModule":false,"hasPolis":false,"paragraphCount":24,"wordCount":892},"headData":{"title":"Approval of Cheaper Hepatitis C Drug Will Likely Expand Treatment | KQED","description":"Mavyret, recently approved by the Food And Drug Administration, can cure hepatitis C in eight weeks, at a cost of $26,400. Though still expensive, that's well below the price of other options.","ogTitle":"","ogDescription":"","ogImgId":"","twTitle":"","twDescription":"","twImgId":"","schema":{"@context":"http://schema.org","@type":"Article","headline":"Approval of Cheaper Hepatitis C Drug Will Likely Expand Treatment","datePublished":"2017-11-03T21:15:20.000Z","dateModified":"2017-11-03T21:15:20.000Z","image":"https://cdn.kqed.org/wp-content/uploads/2020/02/KQED-OG-Image@1x.png"}},"disqusIdentifier":"436058 https://ww2.kqed.org/futureofyou/?p=436058","disqusUrl":"https://ww2.kqed.org/futureofyou/2017/11/03/approval-of-cheaper-hepatitis-c-drug-will-likely-expand-treatment/","disqusTitle":"Approval of Cheaper Hepatitis C Drug Will Likely Expand Treatment","nprImageCredit":"James Cavallini","nprByline":"Michelle Andrews\u003cbr />Kaiser Health News","nprImageAgency":"Science Source","nprStoryId":"555156577","nprApiLink":"http://api.npr.org/query?id=555156577&apiKey=MDAxOTAwOTE4MDEyMTkxMDAzNjczZDljZA004","nprHtmlLink":"http://www.npr.org/sections/health-shots/2017/10/04/555156577/fdas-approval-of-a-cheaper-drug-for-hepatitis-c-will-likely-expand-treatment?ft=nprml&f=555156577","nprRetrievedStory":"1","nprPubDate":"Wed, 04 Oct 2017 13:30:00 -0400","nprStoryDate":"Wed, 04 Oct 2017 05:00:16 -0400","nprLastModifiedDate":"Wed, 04 Oct 2017 13:30:45 -0400","path":"/futureofyou/436058/approval-of-cheaper-hepatitis-c-drug-will-likely-expand-treatment","audioTrackLength":null,"parsedContent":[{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003cp>Valerie Green is still waiting to be cured.\u003c/p>\n\u003cp>The Delaware resident was diagnosed with hepatitis C more than two years ago, but she doesn't qualify yet for the Medicaid program's criteria for treatment with a new class of highly effective but pricey drugs.\u003c/p>\n\u003cp>The recent \u003ca href=\"https://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm570038.htm\">approval of a less expensive drug\u003c/a> that generally cures hepatitis C in just eight weeks may make it easier for more insurers and correctional facilities to expand treatment.\u003c/p>\n\u003cp>The drug, \u003ca href=\"https://www.mavyret.com/\">Mavyret\u003c/a>, is the first to be approved by the Food and Drug Administration that can cure all six genetic types of hepatitis C in about two months in patients who haven't previously been treated. Other approved drugs generally require 12 weeks to treat the disease and often aren't effective for all types of hepatitis C.\u003c/p>\n\u003cp>In addition, Mavyret's price tag of $26,400 for a course of treatment is significantly below that of other hepatitis C drugs whose sticker price ranges from about $55,000 to $95,000 to beat the disease. Patients and \u003ca href=\"https://www.macpac.gov/wp-content/uploads/2017/03/High-Cost-HCV-Drugs-in-Medicaid-Final-Report.pdf\">insurers often pay less\u003c/a>, however, through negotiated insurance discounts and rebates.\u003c/p>\n\u003cp>\u003c/p>\u003c/div>","attributes":{"named":{},"numeric":[]}},{"type":"component","content":"","name":"ad","attributes":{"named":{"label":"fullwidth"},"numeric":["fullwidth"]}},{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003c/p>\n\u003cp>\"It certainly stands to reason that the continual march downward on cost would lead to continual opening up of criteria,\" says \u003ca href=\"http://medicaiddirectors.org/about/staff/\">Matt Salo\u003c/a>, executive director of the National Association of Medicaid Directors.\u003c/p>\n\u003cp>Hepatitis C \u003ca href=\"https://www.cdc.gov/hepatitis/hcv/cfaq.htm#cFAQ13\">is a viral liver infection\u003c/a> spread through blood that affects an estimated 3.5 million people in the United States. It can take years to cause problems. Many baby boomers who contracted it decades ago before blood was screened for the virus don't realize they have it until they develop liver disease. In addition, the growing heroin epidemic is adding to the problem as people become infected by \u003ca href=\"http://www.npr.org/sections/health-shots/2017/08/29/547054395/syringe-exchange-program-aims-to-slow-hepatitis-c-infections-in-alaska\">sharing contaminated needles\u003c/a>.\u003c/p>\n\u003cp>\"Direct-acting antiviral\" therapies like Harvoni, a once-a-day pill introduced in 2014 that generally cured hepatitis C in 12 weeks, are \u003ca href=\"http://www.cochrane.org/CD012143/LIVER_direct-acting-antivirals-chronic-hepatitis-c\">much more effective\u003c/a> than earlier treatments that required weekly interferon injections and multiple daily pills for nearly a year. But the newer regimens came at a price: $94,500, in Harvoni's case.\u003c/p>\n\u003cp>State Medicaid programs, which cover a high proportion of people with hepatitis C, \u003ca href=\"http://www.npr.org/sections/health-shots/2015/12/27/460086615/states-deny-pricey-hepatitis-c-drugs-to-most-medicaid-patients\">balked at the high prices\u003c/a>, even with the 23 percent drug discount the programs typically receive. Many threw up roadblocks to limit drug approval until the disease was advanced. Some required people to be drug- and alcohol-free for six months or more before treatment would be approved.\u003c/p>\n\u003cp>Those moves prompted advocates to push for better access, in some cases \u003ca href=\"https://khn.org/news/medicaid-private-insurers-begin-to-lift-curbs-on-pricey-hepatitis-c-drugs/\">filing suit\u003c/a> to force the programs to cover more people.\u003c/p>\n\u003cp>Faced with a lawsuit in Delaware, the state Medicaid program began loosening up treatment criteria this year, and in January will begin approving enrollees \u003ca href=\"https://www.chlpi.org/wp-content/uploads/2016/06/DMMA-Prior-Authorization-Policy.pdf\">regardless of the severity\u003c/a> of their disease.\u003c/p>\n\u003cp>The state joins more than a dozen others that no longer (or never did) restrict hepatitis C treatment based on disease severity, says \u003ca href=\"http://hls.harvard.edu/faculty/directory/11694/Costello\">Kevin Costello\u003c/a>, director of litigation at Harvard Law School's Center for Health Law and Policy Innovation, which has been a \u003ca href=\"https://www.chlpi.org/in-face-of-class-action-lawsuit-delaware-medicaid-removes-unlawful-restrictions-to-the-cure-for-the-hepatitis-c-virus/\">key player in litigation\u003c/a> in Delaware and other states.\u003c/p>\n\u003cp>It can't happen soon enough, says Green. She is 58 and believes she contracted the disease 31 years ago when she suffered complications during childbirth and required a blood transfusion. Although her liver isn't damaged, Green says, she has suffered with abdominal and joint pain, weight loss and fatigue for decades – all \u003ca href=\"https://www.cdc.gov/hepatitis/hcv/cfaq.htm#cFAQ41\">symptoms\u003c/a> her doctors attribute to the hepatitis C virus.\u003c/p>\n\u003cp>\"It's been a difficult fight for us Medicaid patients,\" she says.\u003c/p>\n\u003cp>People who are incarcerated face an even tougher battle to get treatment for hepatitis C. A recent study of state prisoners suggested that roughly \u003ca href=\"https://www.ncbi.nlm.nih.gov/pubmed/27702964\">17 percent of prisoners are infected\u003c/a> with hepatitis C, compared with about 1 percent of the general population.\u003c/p>\n\u003cp>Prisons have a duty not to be deliberately indifferent to the medical needs of incarcerated people. Prisons don't get the price discounts that the Medicaid programs have, and their budgets are fixed.\u003c/p>\n\u003cp>\"Administrators have to make do with what is there,\" says \u003ca href=\"https://sph.emory.edu/faculty/profile/#!aspauld\">Dr. Anne Spaulding\u003c/a>, an epidemiologist and associate professor at Emory University's public health school, who has worked as a medical director in corrections and published research on hepatitis C among prisoners.\u003c/p>\n\u003cp>Lawyers in a handful of states are pursuing class action lawsuits to force prisons to provide hepatitis C treatment. Mavyret may make a difference, says \u003ca href=\"https://www.law.upenn.edu/cf/faculty/drudovsk/\">David Rudovsky\u003c/a>, a civil rights lawyer who's litigating a class action lawsuit against the Pennsylvania Department of Corrections.\u003c/p>\n\u003cp>\"Everyone recognizes that it's going to make it easier to cover people,\" he says.\u003c/p>\n\u003cp>Coverage for drugs that treat hepatitis C is typically less problematic for people who have private insurance (though some obstacles remain). For example, Mavyret is one of seven hepatitis C drugs that are included in the 2018 \u003ca href=\"http://lab.express-scripts.com/lab/insights/drug-options/2018-national-preferred-formulary\">national preferred formulary\u003c/a> by Express Scripts, which manages the pharmacy benefits for 83 million people.\u003c/p>\n\u003cp>\"The benefit to patients and payers is the additional competition, which brings down costs across the class, thus resulting in greater access and affordability,\" says \u003ca href=\"http://lab.express-scripts.com/about/media-inquiries\">Jennifer Luddy\u003c/a>, director of corporate communications at Express Scripts.\u003c/p>\n\u003cp>\u003c/p>\n\u003cp>\u003cem>Kaiser Health News is an editorially independent news service that is part of the nonpartisan Henry J. Kaiser Family Foundation. Follow Michelle Andrews on Twitter: \u003c/em>\u003ca href=\"https://twitter.com/mandrews110\">@mandrews110\u003c/a>.\u003c/p>\n\u003cdiv class=\"fullattribution\">Copyright 2017 Kaiser Health News. To see more, visit \u003ca href=\"http://www.kaiserhealthnews.org/\">Kaiser Health News\u003c/a>.\u003cimg src=\"https://www.google-analytics.com/__utm.gif?utmac=UA-5828686-4&utmdt=FDA%27s+Approval+Of+A+Cheaper+Drug+For+Hepatitis+C+Will+Likely+Expand+Treatment&utme=8(APIKey)9(MDAxOTAwOTE4MDEyMTkxMDAzNjczZDljZA004)\">\u003c/div>\n\n\u003c/div>\u003c/p>","attributes":{"named":{},"numeric":[]}}],"link":"/futureofyou/436058/approval-of-cheaper-hepatitis-c-drug-will-likely-expand-treatment","authors":["byline_futureofyou_436058"],"categories":["futureofyou_1062","futureofyou_1"],"tags":["futureofyou_736","futureofyou_1387"],"featImg":"futureofyou_436819","label":"futureofyou"},"futureofyou_104998":{"type":"posts","id":"futureofyou_104998","meta":{"index":"posts_1591205157","site":"futureofyou","id":"104998","score":null,"sort":[1454089811000]},"guestAuthors":[],"slug":"new-hepatitis-c-drug-could-bring-down-cost-of-treatment","title":"New Hepatitis C Drug Could Bring Down Cost of Treatment","publishDate":1454089811,"format":"aside","headTitle":"Future of You | KQED Future of You | KQED Science","labelTerm":{"term":54,"site":"futureofyou"},"content":"\u003cp>Patients with hepatitis C have yet another advanced treatment option, as the Food and Drug Administration on Thursday approved a new once-a-day pill developed by drugmaker Merck.\u003c/p>\n\u003cp>The FDA said Merck can begin marketing Zepatier for patients with two of the subtypes the liver-destroying virus, types 1 and 4. The combination pill includes the medications elbasvir and grazoprevir, which attack the virus in two different ways.\u003c/p>\n\u003cp>Merck & Co. said the price will be $54,600 for a 12-week treatment regimen. Insurers will likely still demand some discounts on that price.\u003c/p>\n\u003cp>The approval is good news for patients, because the growing competition should crimp the sky-high prices for hepatitis C drugs, and the additional option means there's one that will work for nearly every subgroup of people with hepatitis C.\u003c/p>\n\u003cp>[contextly_sidebar id=\"SdBBGkqABQOruS25weRmHsTLEh9KZIaJ\"]Roughly 3 million Americans and millions more in other countries have the blood-borne virus, which doesn't produce symptoms — jaundice, fluid accumulation in the abdomen, bleeding and infections — until significant damage has been done. Many develop liver cancer or cirrhosis and require a liver transplant, but die before a match is available.\u003c/p>\n\u003cp>[ad fullwidth]\u003c/p>\n\u003cp>There are six genetic subtypes of the hepatitis C virus, and the five drugs now approved in the U.S. generally only treat some of those. Patients with both hepatitis C and HIV or another serious condition are particularly difficult to treat, as are those who already have severe liver or kidney damage. Some of the drugs target those patient groups; Merck's is approved for patients with cirrhosis, for example.\u003c/p>\n\u003cp>The five hepatitis C treatments all can cure 90 percent of patients or better in three months or less. By comparison, the prior generation of treatments took a year, barely cured half of patients and required both daily pills and frequent shots of immune-system stimulator interferon. That caused awful flu-like side effects many patients could not tolerate.\u003c/p>\n\u003cp>Merck's Zepatier was approved for treating patients with hepatitis C genotype 1, the most common type in the U.S., and gentopye 4, one of the least common. It was tested in a total of 1,373 patients, with or without liver cirrhosis.\u003c/p>\n\u003cp>Twelve weeks after treatment ended, 94 percent to 97 percent of those with genotype 1, and 97 percent to 100 percent of those with genotype 4, had no virus detectable in their blood, suggesting they'd been cured, according to the FDA.\u003c/p>\n\u003cp>The drug's side effects include fatigue, headache, nausea and problems with liver function.\u003c/p>\n\u003cp>The increasing competition will help insurers and other payers win bigger discounts from all the makers of hepatitis C drugs. That includes market leader Gilead Sciences Inc., which makes Harvoni and Sovaldi; AbbVie Inc., which makes Viekira Pak; Bristol-Myers Squibb Co., which makes Daklinza, and Merck.\u003c/p>\n\u003cp>Harvoni carries a list price of $94,000 for one course of treatment, but insurers have been getting discounts of about 45 percent off that to include the drug on their formulary of covered medicines. It's far and away the market leader.\u003c/p>\n\u003cp>Merck said the list price for Zepatier is in the range of what it believes are the net prices competitors are getting from payers.\u003c/p>\n\u003cp>\u003c/p>\n\u003cp>Also on Thursday, Bristol-Myers said the European Union approved sales there for Daklinza, which won U.S. approval in 2004.\u003c/p>\n\n","blocks":[],"excerpt":"The FDA on Thursday approved a new once-a-day pill developed by drugmaker Merck.","status":"publish","parent":0,"modified":1454534802,"stats":{"hasAudio":false,"hasVideo":false,"hasChartOrMap":false,"iframeSrcs":[],"hasGoogleForm":false,"hasGallery":false,"hasHearkenModule":false,"hasPolis":false,"paragraphCount":16,"wordCount":561},"headData":{"title":"New Hepatitis C Drug Could Bring Down Cost of Treatment | KQED","description":"The FDA on Thursday approved a new once-a-day pill developed by drugmaker Merck.","ogTitle":"","ogDescription":"","ogImgId":"","twTitle":"","twDescription":"","twImgId":"","schema":{"@context":"http://schema.org","@type":"Article","headline":"New Hepatitis C Drug Could Bring Down Cost of Treatment","datePublished":"2016-01-29T17:50:11.000Z","dateModified":"2016-02-03T21:26:42.000Z","image":"https://cdn.kqed.org/wp-content/uploads/2020/02/KQED-OG-Image@1x.png"}},"disqusIdentifier":"104998 http://ww2.kqed.org/futureofyou/?p=104998","disqusUrl":"https://ww2.kqed.org/futureofyou/2016/01/29/new-hepatitis-c-drug-could-bring-down-cost-of-treatment/","disqusTitle":"New Hepatitis C Drug Could Bring Down Cost of Treatment","nprByline":"Linda A. Johnson\u003cbr />Associated Press","path":"/futureofyou/104998/new-hepatitis-c-drug-could-bring-down-cost-of-treatment","audioTrackLength":null,"parsedContent":[{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003cp>Patients with hepatitis C have yet another advanced treatment option, as the Food and Drug Administration on Thursday approved a new once-a-day pill developed by drugmaker Merck.\u003c/p>\n\u003cp>The FDA said Merck can begin marketing Zepatier for patients with two of the subtypes the liver-destroying virus, types 1 and 4. The combination pill includes the medications elbasvir and grazoprevir, which attack the virus in two different ways.\u003c/p>\n\u003cp>Merck & Co. said the price will be $54,600 for a 12-week treatment regimen. Insurers will likely still demand some discounts on that price.\u003c/p>\n\u003cp>The approval is good news for patients, because the growing competition should crimp the sky-high prices for hepatitis C drugs, and the additional option means there's one that will work for nearly every subgroup of people with hepatitis C.\u003c/p>\n\u003cp>\u003c/p>\u003cp>\u003c/p>\u003cp>Roughly 3 million Americans and millions more in other countries have the blood-borne virus, which doesn't produce symptoms — jaundice, fluid accumulation in the abdomen, bleeding and infections — until significant damage has been done. Many develop liver cancer or cirrhosis and require a liver transplant, but die before a match is available.\u003c/p>\n\u003cp>\u003c/p>\u003c/div>","attributes":{"named":{},"numeric":[]}},{"type":"component","content":"","name":"ad","attributes":{"named":{"label":"fullwidth"},"numeric":["fullwidth"]}},{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003c/p>\n\u003cp>There are six genetic subtypes of the hepatitis C virus, and the five drugs now approved in the U.S. generally only treat some of those. Patients with both hepatitis C and HIV or another serious condition are particularly difficult to treat, as are those who already have severe liver or kidney damage. Some of the drugs target those patient groups; Merck's is approved for patients with cirrhosis, for example.\u003c/p>\n\u003cp>The five hepatitis C treatments all can cure 90 percent of patients or better in three months or less. By comparison, the prior generation of treatments took a year, barely cured half of patients and required both daily pills and frequent shots of immune-system stimulator interferon. That caused awful flu-like side effects many patients could not tolerate.\u003c/p>\n\u003cp>Merck's Zepatier was approved for treating patients with hepatitis C genotype 1, the most common type in the U.S., and gentopye 4, one of the least common. It was tested in a total of 1,373 patients, with or without liver cirrhosis.\u003c/p>\n\u003cp>Twelve weeks after treatment ended, 94 percent to 97 percent of those with genotype 1, and 97 percent to 100 percent of those with genotype 4, had no virus detectable in their blood, suggesting they'd been cured, according to the FDA.\u003c/p>\n\u003cp>The drug's side effects include fatigue, headache, nausea and problems with liver function.\u003c/p>\n\u003cp>The increasing competition will help insurers and other payers win bigger discounts from all the makers of hepatitis C drugs. That includes market leader Gilead Sciences Inc., which makes Harvoni and Sovaldi; AbbVie Inc., which makes Viekira Pak; Bristol-Myers Squibb Co., which makes Daklinza, and Merck.\u003c/p>\n\u003cp>Harvoni carries a list price of $94,000 for one course of treatment, but insurers have been getting discounts of about 45 percent off that to include the drug on their formulary of covered medicines. It's far and away the market leader.\u003c/p>\n\u003cp>Merck said the list price for Zepatier is in the range of what it believes are the net prices competitors are getting from payers.\u003c/p>\n\u003cp>\u003c/p>\n\u003cp>Also on Thursday, Bristol-Myers said the European Union approved sales there for Daklinza, which won U.S. approval in 2004.\u003c/p>\n\n\u003c/div>\u003c/p>","attributes":{"named":{},"numeric":[]}}],"link":"/futureofyou/104998/new-hepatitis-c-drug-could-bring-down-cost-of-treatment","authors":["byline_futureofyou_104998"],"programs":["futureofyou_54"],"categories":["futureofyou_452"],"tags":["futureofyou_736","futureofyou_80","futureofyou_737","futureofyou_738"],"featImg":"futureofyou_105002","label":"futureofyou_54"}},"programsReducer":{"possible":{"id":"possible","title":"Possible","info":"Possible is hosted by entrepreneur Reid Hoffman and writer Aria Finger. Together in Possible, Hoffman and Finger lead enlightening discussions about building a brighter collective future. The show features interviews with visionary guests like Trevor Noah, Sam Altman and Janette Sadik-Khan. Possible paints an optimistic portrait of the world we can create through science, policy, business, art and our shared humanity. It asks: What if everything goes right for once? How can we get there? Each episode also includes a short fiction story generated by advanced AI GPT-4, serving as a thought-provoking springboard to speculate how humanity could leverage technology for good.","airtime":"SUN 2pm","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/Possible-Podcast-Tile-360x360-1.jpg","officialWebsiteLink":"https://www.possible.fm/","meta":{"site":"news","source":"Possible"},"link":"/radio/program/possible","subscribe":{"apple":"https://podcasts.apple.com/us/podcast/possible/id1677184070","spotify":"https://open.spotify.com/show/730YpdUSNlMyPQwNnyjp4k"}},"1a":{"id":"1a","title":"1A","info":"1A is home to the national conversation. 1A brings on great guests and frames the best debate in ways that make you think, share and engage.","airtime":"MON-THU 11pm-12am","imageSrc":"https://ww2.kqed.org/radio/wp-content/uploads/sites/50/2018/04/1a.jpg","officialWebsiteLink":"https://the1a.org/","meta":{"site":"news","source":"npr"},"link":"/radio/program/1a","subscribe":{"npr":"https://rpb3r.app.goo.gl/RBrW","apple":"https://itunes.apple.com/WebObjects/MZStore.woa/wa/viewPodcast?s=143441&mt=2&id=1188724250&at=11l79Y&ct=nprdirectory","tuneIn":"https://tunein.com/radio/1A-p947376/","rss":"https://feeds.npr.org/510316/podcast.xml"}},"all-things-considered":{"id":"all-things-considered","title":"All Things Considered","info":"Every weekday, \u003cem>All Things Considered\u003c/em> hosts Robert Siegel, Audie Cornish, Ari Shapiro, and Kelly McEvers present the program's trademark mix of news, interviews, commentaries, reviews, and offbeat features. 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But is this once sleepy suburb ready for them?","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/American-Suburb-Podcast-Tile-703x703-1.jpg","officialWebsiteLink":"/news/series/american-suburb-podcast","meta":{"site":"news","source":"kqed","order":"13"},"link":"/news/series/american-suburb-podcast/","subscribe":{"npr":"https://rpb3r.app.goo.gl/RBrW","apple":"https://itunes.apple.com/WebObjects/MZStore.woa/wa/viewPodcast?mt=2&id=1287748328","tuneIn":"https://tunein.com/radio/American-Suburb-p1086805/","rss":"https://ww2.kqed.org/news/series/american-suburb-podcast/feed/podcast","google":"https://podcasts.google.com/feed/aHR0cHM6Ly9mZWVkcy5tZWdhcGhvbmUuZm0vS1FJTkMzMDExODgxNjA5"}},"baycurious":{"id":"baycurious","title":"Bay Curious","tagline":"Exploring the Bay Area, one question at a time","info":"KQED’s new podcast, Bay Curious, gets to the bottom of the mysteries — both profound and peculiar — that give the Bay Area its unique identity. And we’ll do it with your help! You ask the questions. You decide what Bay Curious investigates. And you join us on the journey to find the answers.","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/Bay-Curious-Podcast-Tile-703x703-1.jpg","imageAlt":"\"KQED Bay Curious","officialWebsiteLink":"/news/series/baycurious","meta":{"site":"news","source":"kqed","order":"4"},"link":"/podcasts/baycurious","subscribe":{"apple":"https://podcasts.apple.com/us/podcast/bay-curious/id1172473406","npr":"https://www.npr.org/podcasts/500557090/bay-curious","rss":"https://ww2.kqed.org/news/category/bay-curious-podcast/feed/podcast","google":"https://podcasts.google.com/feed/aHR0cHM6Ly93dzIua3FlZC5vcmcvbmV3cy9jYXRlZ29yeS9iYXktY3VyaW91cy1wb2RjYXN0L2ZlZWQvcG9kY2FzdA","stitcher":"https://www.stitcher.com/podcast/kqed/bay-curious","spotify":"https://open.spotify.com/show/6O76IdmhixfijmhTZLIJ8k"}},"bbc-world-service":{"id":"bbc-world-service","title":"BBC World Service","info":"The day's top stories from BBC News compiled twice daily in the week, once at weekends.","airtime":"MON-FRI 9pm-10pm, TUE-FRI 1am-2am","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/BBC-World-Service-Podcast-Tile-360x360-1.jpg","officialWebsiteLink":"https://www.bbc.co.uk/sounds/play/live:bbc_world_service","meta":{"site":"news","source":"BBC World Service"},"link":"/radio/program/bbc-world-service","subscribe":{"apple":"https://itunes.apple.com/us/podcast/global-news-podcast/id135067274?mt=2","tuneIn":"https://tunein.com/radio/BBC-World-Service-p455581/","rss":"https://podcasts.files.bbci.co.uk/p02nq0gn.rss"}},"code-switch-life-kit":{"id":"code-switch-life-kit","title":"Code Switch / Life Kit","info":"\u003cem>Code Switch\u003c/em>, which listeners will hear in the first part of the hour, has fearless and much-needed conversations about race. Hosted by journalists of color, the show tackles the subject of race head-on, exploring how it impacts every part of society — from politics and pop culture to history, sports and more.\u003cbr />\u003cbr />\u003cem>Life Kit\u003c/em>, which will be in the second part of the hour, guides you through spaces and feelings no one prepares you for — from finances to mental health, from workplace microaggressions to imposter syndrome, from relationships to parenting. The show features experts with real world experience and shares their knowledge. Because everyone needs a little help being human.\u003cbr />\u003cbr />\u003ca href=\"https://www.npr.org/podcasts/510312/codeswitch\">\u003cem>Code Switch\u003c/em> offical site and podcast\u003c/a>\u003cbr />\u003ca href=\"https://www.npr.org/lifekit\">\u003cem>Life Kit\u003c/em> offical site and podcast\u003c/a>\u003cbr />","airtime":"SUN 9pm-10pm","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/Code-Switch-Life-Kit-Podcast-Tile-360x360-1.jpg","meta":{"site":"radio","source":"npr"},"link":"/radio/program/code-switch-life-kit","subscribe":{"apple":"https://podcasts.apple.com/podcast/1112190608?mt=2&at=11l79Y&ct=nprdirectory","google":"https://podcasts.google.com/feed/aHR0cHM6Ly93d3cubnByLm9yZy9yc3MvcG9kY2FzdC5waHA_aWQ9NTEwMzEy","spotify":"https://open.spotify.com/show/3bExJ9JQpkwNhoHvaIIuyV","rss":"https://feeds.npr.org/510312/podcast.xml"}},"commonwealth-club":{"id":"commonwealth-club","title":"Commonwealth Club of California Podcast","info":"The Commonwealth Club of California is the nation's oldest and largest public affairs forum. 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