U.S. Screens More Staff in China Over Mystery Health Issues
Once Lethal, Multiple Myeloma May Be In A ‘Golden Age’ Of Treatment
Common Blood Tests May Help Predict Chronic Disease Risk
Why “Smart Clothing” is the Next Frontier for Wearable Health Tech
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She is also co-founder of Ladies Who Vino, a networking group for women in technology and business.","avatar":"https://secure.gravatar.com/avatar/22c63869a7901c61c15e204391c1261d?s=600&d=blank&r=g","twitter":null,"facebook":null,"instagram":null,"linkedin":null,"sites":[{"site":"futureofyou","roles":["administrator"]},{"site":"stateofhealth","roles":["author"]},{"site":"science","roles":["editor"]}],"headData":{"title":"Christina Farr | KQED","description":null,"ogImgSrc":"https://secure.gravatar.com/avatar/22c63869a7901c61c15e204391c1261d?s=600&d=blank&r=g","twImgSrc":"https://secure.gravatar.com/avatar/22c63869a7901c61c15e204391c1261d?s=600&d=blank&r=g"},"isLoading":false,"link":"/author/cfarr"}},"breakingNewsReducer":{},"campaignFinanceReducer":{},"firebase":{"requesting":{},"requested":{},"timestamps":{},"data":{},"ordered":{},"auth":{"isLoaded":false,"isEmpty":true},"authError":null,"profile":{"isLoaded":false,"isEmpty":true},"listeners":{"byId":{},"allIds":[]},"isInitializing":false,"errors":[]},"navBarReducer":{"navBarId":"home","fullView":true,"showPlayer":false},"navMenuReducer":{"menus":[{"key":"menu1","items":[{"name":"News","link":"/","type":"title"},{"name":"Politics","link":"/politics"},{"name":"Science","link":"/science"},{"name":"Education","link":"/educationnews"},{"name":"Housing","link":"/housing"},{"name":"Immigration","link":"/immigration"},{"name":"Criminal Justice","link":"/criminaljustice"},{"name":"Silicon Valley","link":"/siliconvalley"},{"name":"Forum","link":"/forum"},{"name":"The California Report","link":"/californiareport"}]},{"key":"menu2","items":[{"name":"Arts & Culture","link":"/arts","type":"title"},{"name":"Critics’ Picks","link":"/thedolist"},{"name":"Cultural Commentary","link":"/artscommentary"},{"name":"Food & Drink","link":"/food"},{"name":"Bay Area Hip-Hop","link":"/bayareahiphop"},{"name":"Rebel Girls","link":"/rebelgirls"},{"name":"Arts Video","link":"/artsvideos"}]},{"key":"menu3","items":[{"name":"Podcasts","link":"/podcasts","type":"title"},{"name":"Bay Curious","link":"/podcasts/baycurious"},{"name":"Rightnowish","link":"/podcasts/rightnowish"},{"name":"The Bay","link":"/podcasts/thebay"},{"name":"On Our Watch","link":"/podcasts/onourwatch"},{"name":"Mindshift","link":"/podcasts/mindshift"},{"name":"Consider This","link":"/podcasts/considerthis"},{"name":"Political Breakdown","link":"/podcasts/politicalbreakdown"}]},{"key":"menu4","items":[{"name":"Live Radio","link":"/radio","type":"title"},{"name":"TV","link":"/tv","type":"title"},{"name":"Events","link":"/events","type":"title"},{"name":"For Educators","link":"/education","type":"title"},{"name":"Support KQED","link":"/support","type":"title"},{"name":"About","link":"/about","type":"title"},{"name":"Help Center","link":"https://kqed-helpcenter.kqed.org/s","type":"title"}]}]},"pagesReducer":{},"postsReducer":{"stream_live":{"type":"live","id":"stream_live","audioUrl":"https://streams.kqed.org/kqedradio","title":"Live Stream","excerpt":"Live Stream information currently unavailable.","link":"/radio","featImg":"","label":{"name":"KQED Live","link":"/"}},"stream_kqedNewscast":{"type":"posts","id":"stream_kqedNewscast","audioUrl":"https://www.kqed.org/.stream/anon/radio/RDnews/newscast.mp3?_=1","title":"KQED Newscast","featImg":"","label":{"name":"88.5 FM","link":"/"}},"futureofyou_442385":{"type":"posts","id":"futureofyou_442385","meta":{"index":"posts_1591205157","site":"futureofyou","id":"442385","score":null,"sort":[1528385114000]},"guestAuthors":[],"slug":"us-screens-more-staff-in-china-over-mystery-health-issues","title":"U.S. Screens More Staff in China Over Mystery Health Issues","publishDate":1528385114,"format":"standard","headTitle":"KQED Future of You | KQED Science","labelTerm":{},"content":"\u003cp>A U.S. medical team was screening more Americans who work at the consulate in southern China as the State Department confirmed evacuating a number of government employees who experienced unexplained health issues like those that have hurt U.S. personnel in Cuba and China.[contextly_sidebar id=\"7CkyzwzKuv3WHlXibNMNiakYleGV6oAv\"]\u003c/p>\n\u003cp>The evacuations of workers in Guangzhou followed medical testing that revealed they might have been affected. State Department spokeswoman Heather Nauert said “a number of individuals” had been brought to the U.S. but didn’t say how many were affected or evacuated. A previous case in Guangzhou, disclosed last month, prompted the tests.\u003c/p>\n\u003cp>Nauert also said that remaining U.S. government personnel and their families in Guangzhou would also be able to request testing if they “noted concerning symptoms or wanted baseline screening.”\u003c/p>\n\u003cp>The incidents have raised fears the unexplained issues that started in Cuba in 2016 have expanded. The U.S. government has deemed those incidents “specific attacks” on American workers but hasn’t publicly identified a cause or culprit. Most of the incidents were accompanied by bizarre, unexplained sounds that initially led U.S. investigators to suspect a sonic attack.\u003c/p>\n\u003cp>Symptoms have included dizziness, headaches and an inability to concentrate. The American government worker who previously was removed from China reported “subtle and vague, but abnormal, sensations of sound and pressure,” the Guangzhou consulate reported last month\u003c/p>\n\u003cp>[ad fullwidth]\u003c/p>\n\u003cp>Security guards outside the Guangzhou consulate on Thursday told reporters to leave the area and not attempt to talk to consulate staff.\u003c/p>\n\u003cp>Asked about the latest incidents, Chinese Foreign Ministry spokeswoman Hua Chunying said the U.S. had not formally raised the matter with Beijing.\u003c/p>\n\u003cp>“If the U.S. makes formal contact with us, China will continue necessary investigations in an earnest and responsible manner and maintain close communication and cooperation with the U.S.,” Hua said at a regularly scheduled news conference.[contextly_sidebar id=\"kD7HyExDaX6bPoHIJ2EyalwLhMsGc6Yg\"]\u003c/p>\n\u003cp>China earlier said it had looked into the case announced last month but came up with no clues about the cause of the symptoms.\u003c/p>\n\u003cp>The New York Times identified the latest American employee evacuated as Mark A. Lenzi, a security engineering officer at the consulate who left Wednesday night with his wife and two children.\u003c/p>\n\u003cp>\u003c/p>\n\u003cp>Lenzi told the Times he resided in the same apartment tower as the officer evacuated in April and suffered in recent months from what he called “neurological symptoms.”\u003c/p>\n\u003cdiv id=\"div-gpt-ad-1470255291270-1\" class=\"ad-placeholder\">\n\u003cdiv id=\"google_ads_iframe_/15786418/APNews/site/article/midarticle2_0__container__\">\n\u003cp>Lenzi’s apartment was in one of several high-rise buildings in The Canton Place featuring restaurants and galleries spaced around a central plaza. Another diplomat who reported symptoms was at a different upscale building near the consulate, the paper said.\u003c/p>\n\u003cp>A U.S. official, who wasn’t authorized to discuss the situation publicly and requested anonymity, said the evacuated American government workers were being brought from China for testing to the University of Pennsylvania. That’s where doctors have been treating and studying patients previously evacuated from the U.S. Embassy in Havana.\u003c/p>\n\u003cp>The preliminary findings of the medical reports on the 24 personnel affected in Cuba showed they had sensory and memory problems similar to the brain dysfunction seen with concussions.\u003c/p>\n\u003cp>The Penn team said the patients from Cuba experienced persistent disability though rehabilitation therapy customized for them seemed to help.\u003c/p>\n\u003cp>Canada in April also ordered families of diplomatic staff in Cuba to return home after mysterious health symptoms were detected in 10 Canadians stationed on the island. Canada said the 10 continued to show unexplained brain symptoms and that “medical information raised concerns for a new type of a possible acquired brain injury.”[contextly_sidebar id=\"yqjMydejhDpIpH1sD1HMACrcUU3kDG2I\"]\u003c/p>\n\u003cp>In testimony before the Senate Foreign Relations Committee last month about the first case in China, U.S. Secretary of State Mike Pompeo said China had “said all the right things and have demonstrated their willingness to help us identify the vector which led to this medical incident.”\u003c/p>\n\u003cp>The China incidents affect one of the most important of the seven U.S. diplomatic outposts in the country. The Guangzhou consulate opened months after the establishment of diplomatic relations between Beijing and Washington in 1979 and moved to its new purpose-built facility in 2013.\u003c/p>\n\u003cp>It serves four southern provinces with a combined population of more than 204 million and processes more than 1 million visa applications of all types annually. It is also the only U.S. diplomatic installation in China authorized to process immigrant visas and handle adoptions.\u003c/p>\n\u003cp>People working in The Canton Place complex, a few kilometers (miles) from the consulate, said they were just hearing about the incidents, reflecting a lack of coverage in China’s entirely state-controlled media.\u003c/p>\n\u003cp>Aled Williams, a British teacher at a kindergarten said Thursday that the reports sounded “sci-fi-ish.”\u003c/p>\n\u003cp>“Hard to get my head around how it works,” he said. “Better watch myself.”\u003c/p>\n\u003cp>Linda Chen, who runs a coffee shop in the area, said she was mystified as to why only certain people seemed to have been affected in an area known for its comfort and safety.\u003c/p>\n\u003cp>“For me I feel it’s very strange. But I don’t feel that there’s something to be very afraid of because it’s probably a very special case,” Chen said.\u003c/p>\n\u003c/div>\n\u003c/div>\n\n","blocks":[],"excerpt":"The incidents have raised fears the unexplained issues that started in Cuba in 2016 have expanded. The U.S. government has deemed those incidents “specific attacks” but hasn’t publicly identified a cause or culprit. ","status":"publish","parent":0,"modified":1528389166,"stats":{"hasAudio":false,"hasVideo":false,"hasChartOrMap":false,"iframeSrcs":[],"hasGoogleForm":false,"hasGallery":false,"hasHearkenModule":false,"hasPolis":false,"paragraphCount":26,"wordCount":902},"headData":{"title":"U.S. Screens More Staff in China Over Mystery Health Issues | KQED","description":"The incidents have raised fears the unexplained issues that started in Cuba in 2016 have expanded. The U.S. government has deemed those incidents “specific attacks” but hasn’t publicly identified a cause or culprit. ","ogTitle":"","ogDescription":"","ogImgId":"","twTitle":"","twDescription":"","twImgId":"","schema":{"@context":"http://schema.org","@type":"Article","headline":"U.S. Screens More Staff in China Over Mystery Health Issues","datePublished":"2018-06-07T15:25:14.000Z","dateModified":"2018-06-07T16:32:46.000Z","image":"https://cdn.kqed.org/wp-content/uploads/2020/02/KQED-OG-Image@1x.png"}},"disqusIdentifier":"442385 https://ww2.kqed.org/futureofyou/?p=442385","disqusUrl":"https://ww2.kqed.org/futureofyou/2018/06/07/us-screens-more-staff-in-china-over-mystery-health-issues/","disqusTitle":"U.S. Screens More Staff in China Over Mystery Health Issues","source":"Health","nprByline":"Kelvin Chan\u003cbr />Dake Kang\u003cbr />The Associated Press","path":"/futureofyou/442385/us-screens-more-staff-in-china-over-mystery-health-issues","audioTrackLength":null,"parsedContent":[{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003cp>A U.S. medical team was screening more Americans who work at the consulate in southern China as the State Department confirmed evacuating a number of government employees who experienced unexplained health issues like those that have hurt U.S. personnel in Cuba and China.\u003c/p>\u003cp>\u003c/p>\u003cp>\u003c/p>\n\u003cp>The evacuations of workers in Guangzhou followed medical testing that revealed they might have been affected. State Department spokeswoman Heather Nauert said “a number of individuals” had been brought to the U.S. but didn’t say how many were affected or evacuated. A previous case in Guangzhou, disclosed last month, prompted the tests.\u003c/p>\n\u003cp>Nauert also said that remaining U.S. government personnel and their families in Guangzhou would also be able to request testing if they “noted concerning symptoms or wanted baseline screening.”\u003c/p>\n\u003cp>The incidents have raised fears the unexplained issues that started in Cuba in 2016 have expanded. The U.S. government has deemed those incidents “specific attacks” on American workers but hasn’t publicly identified a cause or culprit. Most of the incidents were accompanied by bizarre, unexplained sounds that initially led U.S. investigators to suspect a sonic attack.\u003c/p>\n\u003cp>Symptoms have included dizziness, headaches and an inability to concentrate. The American government worker who previously was removed from China reported “subtle and vague, but abnormal, sensations of sound and pressure,” the Guangzhou consulate reported last month\u003c/p>\n\u003cp>\u003c/p>\u003c/div>","attributes":{"named":{},"numeric":[]}},{"type":"component","content":"","name":"ad","attributes":{"named":{"label":"fullwidth"},"numeric":["fullwidth"]}},{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003c/p>\n\u003cp>Security guards outside the Guangzhou consulate on Thursday told reporters to leave the area and not attempt to talk to consulate staff.\u003c/p>\n\u003cp>Asked about the latest incidents, Chinese Foreign Ministry spokeswoman Hua Chunying said the U.S. had not formally raised the matter with Beijing.\u003c/p>\n\u003cp>“If the U.S. makes formal contact with us, China will continue necessary investigations in an earnest and responsible manner and maintain close communication and cooperation with the U.S.,” Hua said at a regularly scheduled news conference.\u003c/p>\u003cp>\u003c/p>\u003cp>\u003c/p>\n\u003cp>China earlier said it had looked into the case announced last month but came up with no clues about the cause of the symptoms.\u003c/p>\n\u003cp>The New York Times identified the latest American employee evacuated as Mark A. Lenzi, a security engineering officer at the consulate who left Wednesday night with his wife and two children.\u003c/p>\n\u003cp>\u003c/p>\n\u003cp>Lenzi told the Times he resided in the same apartment tower as the officer evacuated in April and suffered in recent months from what he called “neurological symptoms.”\u003c/p>\n\u003cdiv id=\"div-gpt-ad-1470255291270-1\" class=\"ad-placeholder\">\n\u003cdiv id=\"google_ads_iframe_/15786418/APNews/site/article/midarticle2_0__container__\">\n\u003cp>Lenzi’s apartment was in one of several high-rise buildings in The Canton Place featuring restaurants and galleries spaced around a central plaza. Another diplomat who reported symptoms was at a different upscale building near the consulate, the paper said.\u003c/p>\n\u003cp>A U.S. official, who wasn’t authorized to discuss the situation publicly and requested anonymity, said the evacuated American government workers were being brought from China for testing to the University of Pennsylvania. That’s where doctors have been treating and studying patients previously evacuated from the U.S. Embassy in Havana.\u003c/p>\n\u003cp>The preliminary findings of the medical reports on the 24 personnel affected in Cuba showed they had sensory and memory problems similar to the brain dysfunction seen with concussions.\u003c/p>\n\u003cp>The Penn team said the patients from Cuba experienced persistent disability though rehabilitation therapy customized for them seemed to help.\u003c/p>\n\u003cp>Canada in April also ordered families of diplomatic staff in Cuba to return home after mysterious health symptoms were detected in 10 Canadians stationed on the island. Canada said the 10 continued to show unexplained brain symptoms and that “medical information raised concerns for a new type of a possible acquired brain injury.”\u003c/p>\u003cp>\u003c/p>\u003cp>\u003c/p>\n\u003cp>In testimony before the Senate Foreign Relations Committee last month about the first case in China, U.S. Secretary of State Mike Pompeo said China had “said all the right things and have demonstrated their willingness to help us identify the vector which led to this medical incident.”\u003c/p>\n\u003cp>The China incidents affect one of the most important of the seven U.S. diplomatic outposts in the country. The Guangzhou consulate opened months after the establishment of diplomatic relations between Beijing and Washington in 1979 and moved to its new purpose-built facility in 2013.\u003c/p>\n\u003cp>It serves four southern provinces with a combined population of more than 204 million and processes more than 1 million visa applications of all types annually. It is also the only U.S. diplomatic installation in China authorized to process immigrant visas and handle adoptions.\u003c/p>\n\u003cp>People working in The Canton Place complex, a few kilometers (miles) from the consulate, said they were just hearing about the incidents, reflecting a lack of coverage in China’s entirely state-controlled media.\u003c/p>\n\u003cp>Aled Williams, a British teacher at a kindergarten said Thursday that the reports sounded “sci-fi-ish.”\u003c/p>\n\u003cp>“Hard to get my head around how it works,” he said. “Better watch myself.”\u003c/p>\n\u003cp>Linda Chen, who runs a coffee shop in the area, said she was mystified as to why only certain people seemed to have been affected in an area known for its comfort and safety.\u003c/p>\n\u003cp>“For me I feel it’s very strange. But I don’t feel that there’s something to be very afraid of because it’s probably a very special case,” Chen said.\u003c/p>\n\u003c/div>\n\u003c/div>\n\n\u003c/div>\u003c/p>","attributes":{"named":{},"numeric":[]}}],"link":"/futureofyou/442385/us-screens-more-staff-in-china-over-mystery-health-issues","authors":["byline_futureofyou_442385"],"categories":["futureofyou_1","futureofyou_73"],"tags":["futureofyou_1263","futureofyou_1225","futureofyou_1516","futureofyou_61"],"collections":["futureofyou_1093"],"featImg":"futureofyou_442389","label":"source_futureofyou_442385"},"futureofyou_442147":{"type":"posts","id":"futureofyou_442147","meta":{"index":"posts_1591205157","site":"futureofyou","id":"442147","score":null,"sort":[1527620458000]},"guestAuthors":[],"slug":"once-lethal-multiple-myeloma-may-be-in-a-golden-age-of-treatment","title":"Once Lethal, Multiple Myeloma May Be In A ‘Golden Age’ Of Treatment","publishDate":1527620458,"format":"standard","headTitle":"KQED Future of You | KQED Science","labelTerm":{"site":"futureofyou"},"content":"\u003cp>If you can call someone who gets a rare form of cancer lucky, then Deb Graff says she fits the bill.[contextly_sidebar id=\"GPKrecPJLp3HW1nQPWhCt1lQA56TdW2K\"]\u003c/p>\n\u003cp>At age 72, Graff has survived nine years with multiple myeloma, a blood cancer whose life expectancy used to be measured in months.\u003c/p>\n\u003cp>“I wasn’t ready to go anywhere,” said Graff, who lives in South Dennis, Mass., on Cape Cod. “I wanted to see my grandkids grow up and still be an aggravation to my husband.”\u003c/p>\n\u003cp>She was lucky enough to get multiple myeloma after the 2003 release of a drug called Velcade (bortezomib), one of the first therapies to directly target multiple myeloma. Velcade, plus more than 20 other approvals since then, have transformed multiple myeloma care. For three-quarters of patients, a disease that once brought a three-year life expectancy has become a long-term, chronic illness.\u003c/p>\n\u003cp>Now, multiple myeloma is poised for another inflection point.\u003c/p>\n\u003cp>[ad fullwidth]\u003c/p>\n\u003cp>There are 89 experimental drugs currently being tested in people, according to Biomedtracker, a research unit of Informa. Some are improvements on existing drugs, others have found new ways to target the cancer cells; a few engage the body’s immune system in the fight.\u003c/p>\n\u003cp>Not all the drugs will make it through the trial process, of course.\u003c/p>\n\u003cp>But on the roster, there may be effective treatments for the one-quarter of patients who haven’t yet been helped by existing drugs. There may be regimens that are less challenging than the daily pills, regular infusions, and frequent doctor’s appointments that Graff and others have to manage. And there may be the long-sought cure.[contextly_sidebar id=\"Gp3ytDdHNsL4MngAJTivyGtR5NE9RGOa\"]\u003c/p>\n\u003cp>“There’s no question it’s a golden age in multiple myeloma drug development,” said Dr. David Reese, a senior vice president at Amgen, which developed the drug Kyprolis (carfilzomib), and is testing five others.\u003c/p>\n\u003cp>“It’s possible that we already are at the juncture where patients diagnosed with this disease could live with this disease for the rest of their lives,” added Dr. Ola Landgren, chief of the Multiple Myeloma Service at Memorial Sloan Kettering Cancer Center in New York.\u003c/p>\n\u003cp>Despite all the advances and optimism, though, most patients with multiple myeloma will still die of multiple myeloma.\u003c/p>\n\u003cp>“It is incurable. I think it is a mistake to suggest otherwise,” said Dr. Paul Richardson, Graff’s physician at the Dana-Farber Cancer Institute in Boston. “I think that this disease is forever humbling.”\u003c/p>\n\u003cp>Every multiple myeloma patient’s disease takes a different path. That makes it hard to understand and even harder to predict.\u003c/p>\n\u003cp>The cancer starts in a subgroup of white blood cells called plasma cells that normally make antibodies to fight infection. When cancerous, these plasma cells produce abnormal proteins that damage organs. But where they wreak havoc can vary from person to person.\u003c/p>\n\u003cp>Many patients suffer crushing fatigue, aching joints, and broken bones. Some get bounced around from one doctor to the next before finally getting a diagnosis.\u003c/p>\n\u003cp>Graff, though, never had a symptom. In late 2009, she went in for a routine physical. She and her husband had just retired, sold their house, and were headed to North Carolina. Ten days after the move, Graff’s primary care doctor back in Massachusetts called and said she’d like to run another blood test.\u003c/p>\n\u003cp>[ad floatright]\u003c/p>\n\u003cp>After her diagnosis and a genetic screen, Graff got more bad news. Her cancer included a genetic mutation called a 17p deletion “that was kind of the kiss of death,” Graff said. Every drug trial she looked at showed positive results for all patients, Graff said, except for those with 17p deletions.\u003c/p>\n\u003cdiv class=\"quote\">\n\u003cdiv class=\"quote-inner\">\n\u003cp>Graff’s younger daughter moved up her wedding to Memorial Day 2010 to make sure her mother could attend. Graff was scheduled for a stem cell transplant six weeks later.[contextly_sidebar id=\"CW17CER3d4Nwi1JxsCyRQtvt2tBYXwpx\"]\u003c/p>\n\u003cp>Unfortunately, like many people with a 17p deletion, the transplant didn’t stick. Instead of staying in remission, by November 2010, she was put on a cocktail of three powerful drugs.\u003c/p>\n\u003cp>With so many approved therapies, doctors like Graff’s can keep switching their patients’ regimens. If one combination stops working, there’s another one to try.\u003c/p>\n\u003cp>“My feeling, and I think it was the right feeling, was that it was my job to stay alive and Paul’s job was to find the next best thing,” she said, referring to her doctor.\u003c/p>\n\u003cp>But still, the disease is tenacious.\u003c/p>\n\u003cp>“It will come back even after remission of five to 10 years,” said Dr. Elisabet Manasanch, an assistant professor in the department of lymphoma/myeloma at the University of Texas MD Anderson Cancer Center in Houston.\u003c/p>\n\u003cdiv class=\"quote\">\n\u003cdiv class=\"quote-inner\">\n\u003cp>There’s no such thing as too many treatment options with a disease as wily as multiple myeloma.\u003c/p>\n\u003cp>“Maybe 1,000 drugs is not enough,” said Martina Sersch, Amgen’s head of global development oncology. “It’s a very clever disease.”\u003c/p>\n\u003cp>And now that patients are living longer, the quality of that extra time matters more, Landgren of Memorial Sloan Kettering said, adding that he expects the next wave of therapies will improve the patient experience.\u003c/p>\n\u003cp>Amgen’s drug Kyprolis, for instance, is currently given twice a week via infusion, but is being tested at a higher, once-a-week dose. Trial results for this regimen will be presented at the American Society for Clinical Oncology annual meeting, which starts Friday.\u003c/p>\n\u003cp>“We may have to attack it from different sides and different pathways to achieve what we ultimately want to achieve, which is a functional cure,” Sersch said.\u003c/p>\n\u003cp>Most patients today start with a combination of treatments: a “veritable Army, Navy, and Air Force,” as Richardson puts it.\u003c/p>\n\u003cp>They get a proteasome inhibitor, often Velcade, to directly attack the myeloma cells; an immunomodulatory treatment such as Revlimid (lenalidomide); and the steroid dexamethasone to tamp down an over-reactive immune system.\u003c/p>\n\u003c/div>\n\u003c/div>\n\u003cp>The Marines, Richardson said, are also coming, in the form of monoclonal antibodies, a type of engineered protein that can bind specifically to cancer cells.\u003c/p>\n\u003cp>The monoclonal antibody\u003csup> \u003c/sup>daratumumab, sold by the Janssen unit of Johnson & Johnson under the brand name Darzalex, was first approved in 2015 for people with late-stage disease. Earlier this month, the Food and Drug Administration \u003ca href=\"https://www.jnj.com/media-center/press-releases/janssen-announces-darzalex-daratumumab-us-fda-approval-for-newly-diagnosed-patients-with-multiple-myeloma-who-are-transplant-ineligible\" target=\"_blank\" rel=\"noopener\">expanded\u003c/a> its approval, allowing it to be used in combination with the standard, three-pronged treatment in newly diagnosed patients.[contextly_sidebar id=\"Rf1TTC48ZJ3mBx4BOYjUCBWVLEGtxBPQ\"]\u003c/p>\n\u003cp>Daratumumab seeks out, binds to, and preferentially kills multiple myeloma cells. In a company-supported study published in the \u003ca href=\"https://www.nejm.org/doi/full/10.1056/NEJMoa1714678?query=featured_home%20-\" target=\"_blank\" rel=\"noopener\">New England Journal of Medicine\u003c/a> in February, 22 percent of patients who used the four-drug combination showed undetectable levels of disease after about 16.5 months. Only 6 percent of patients who used the three-drug combination saw such results.\u003c/p>\n\u003cp>“If you can fundamentally clear all the disease from a patient, now you start to think about, wow — maybe I can get to cure,” said Mark Wildgust, vice president for global medical affairs, oncology, at Janssen.\u003c/p>\n\u003cp>Today’s drugs are so effective that studies take a very long time. In one trial for Kyprolis, for instance, patients who were supposed to be near the end of life survived for 48 months on average, Amgen’s Sersch said. Drug companies will need to find strong, validated criteria other than survival, she said, to provide faster results and potentially drug approvals.\u003c/p>\n\u003cp>Amgen is hoping for game-changing responses to an experimental type of treatment called a BiTE — for bispecific T cell engager. BiTEs essentially are two-armed drugs, Reese said. One arm grabs the tumor cell and the other an immune cell. This activates the immune cell, which kills the cancer cell and primes the immune system to turn against others.\u003c/p>\n\u003cp>It’s too soon to know how long a patient would need to be on BiTE therapy, how to identify which patients might be helped, or how much improvement to expect, Reese said. But because BiTEs train the immune system to fight cancer, they might offer the possibility of a long-term remission or even a cure.\u003c/p>\n\u003cp>Other immune therapies under development include vaccines to amp up the immune system, and an approach called CAR-T, for chimeric antigen receptor T cell. In CAR-T, a patient’s own immune cells are removed and engineered to track down and destroy tumor cells.\u003c/p>\n\u003cp>Richardson, whose first multiple myeloma patient back in 1986 survived just three months, said he’s been amazed by how well CAR-Ts have worked in some of his sickest patients.\u003c/p>\n\u003cp>“I’ve seen the most dramatic responses in CAR-T. They’re quite remarkable,” he said. “Patients who’ve been so ill, and these therapies really made a difference for them beyond what I would expect.”\u003c/p>\n\u003cp>Because CAR-Ts have to be made with the patient’s own T cells, they are expensive and time-consuming; BiTEs are off the shelf and can be mass-produced, theoretically at a lower cost.\u003c/p>\n\u003cfigure id=\"attachment_341074\" class=\"media media-align-center media-break\">\u003ca href=\"https://www.statnews.com/wp-content/uploads/2018/05/multiplemyeloma_01.jpg\">\u003cimg class=\"media-content wp-image-341074 size-large aligncenter\" src=\"https://www.statnews.com/wp-content/uploads/2018/05/multiplemyeloma_01-1024x683.jpg\" alt=\"Multiple Myeloma 03\" width=\"1024\" height=\"683\">\u003c/a>\u003c/figure>\n\u003cp>Cost, of course, is another huge issue in multiple myeloma therapy.\u003c/p>\n\u003cp>Lisa Stephenson, 65, of Whitefish, Mont., who was diagnosed in June 2014, said her multidrug regimen runs about $29,000 a month, plus an occasional $7,000 to boost her immune system. Luckily, nearly all of it is covered by the “incredible insurance” from the law firm where her husband worked until his recent retirement.\u003c/p>\n\u003cp>Stephenson didn’t end up needing a stem cell transplant because an experimental therapy she took at the beginning of her treatment worked so well. But if she had needed it — or needs one in the future — she was told it would cost a minimum of $365,000.\u003c/p>\n\u003cp>“I think to myself, ‘How in the world can people who don’t have good insurance — what do they do?’” she said.\u003c/p>\n\u003cp>It’s not yet clear how much the experimental therapies like BiTEs will cost patients, Amgen’s Reese said. But if these new treatments can produce truly life-altering results, then a one-time large payment, as seen recently with \u003ca href=\"https://www.statnews.com/2018/01/03/spark-gene-therapy-price/\" target=\"_blank\" rel=\"noopener\">gene therapy\u003c/a> and \u003ca href=\"https://www.statnews.com/2017/08/30/novartis-car-t-cancer-approved/\" target=\"_blank\" rel=\"noopener\">CAR-Ts in other types\u003c/a> of blood cancer, might be justifiable. Or, as Wildgust from Janssen put it, “if we can eliminate disease, I’m sure we’ll be able to find a value proposition.”[contextly_sidebar id=\"BsOY9xgwWUtBSlbWPwJOqNCGjfxOKYPZ\"]\u003c/p>\n\u003cp>Stephenson and Graff both said that they still feel like patients much of the time, and that every ache and pain can awaken cancer fears. But they are endlessly grateful for the years the treatments have given them.\u003c/p>\n\u003cp>“Life is good. I can’t complain,” said Stephenson, a mother of three with a strong religious faith. “As bad as myeloma is — and it hasn’t been a picnic by any means — but it has brought so many silver linings. To list them all would take all day.”\u003c/p>\n\u003cp>She doesn’t sweat the small stuff anymore.\u003c/p>\n\u003cp>“So what if you reach for a can of crushed tomatoes and you don’t have any — it’s not the end of the world. Or your stove is dirty. So? I’ll clean it tomorrow if I don’t want to do it today.”\u003c/p>\n\u003cp>Both she and Graff spend time sharing what they’ve learned with patients who are coming up behind them.\u003c/p>\n\u003cp>“I tell people how lucky they are to be diagnosed with multiple myeloma at this time,” said Graff, whose youngest granddaughters are now 4 and 6. “If you have to have it, this is the time.”\u003c/p>\n\u003cdiv class=\"content-meta\"> \u003cem>This \u003ca href=\"https://www.statnews.com/2018/05/29/multiple-myeloma-drug-development/\" target=\"_blank\" rel=\"noopener\">story\u003c/a> was originally published by STAT, an online publication of Boston Globe Media that covers health, medicine, and scientific discovery.\u003c/em>\u003c/div>\n\u003c/div>\n\u003c/div>\n\n","blocks":[],"excerpt":"For three-quarters of patients, a disease that once brought a three-year life expectancy has become a long-term, chronic illness. Now, multiple myeloma is poised for another inflection point.","status":"publish","parent":0,"modified":1527616632,"stats":{"hasAudio":false,"hasVideo":false,"hasChartOrMap":false,"iframeSrcs":[],"hasGoogleForm":false,"hasGallery":false,"hasHearkenModule":false,"hasPolis":false,"paragraphCount":54,"wordCount":2031},"headData":{"title":"Once Lethal, Multiple Myeloma May Be In A ‘Golden Age’ Of Treatment | KQED","description":"For three-quarters of patients, a disease that once brought a three-year life expectancy has become a long-term, chronic illness. Now, multiple myeloma is poised for another inflection point.","ogTitle":"","ogDescription":"","ogImgId":"","twTitle":"","twDescription":"","twImgId":"","schema":{"@context":"http://schema.org","@type":"Article","headline":"Once Lethal, Multiple Myeloma May Be In A ‘Golden Age’ Of Treatment","datePublished":"2018-05-29T19:00:58.000Z","dateModified":"2018-05-29T17:57:12.000Z","image":"https://cdn.kqed.org/wp-content/uploads/2020/02/KQED-OG-Image@1x.png"}},"disqusIdentifier":"442147 https://ww2.kqed.org/futureofyou/?p=442147","disqusUrl":"https://ww2.kqed.org/futureofyou/2018/05/29/once-lethal-multiple-myeloma-may-be-in-a-golden-age-of-treatment/","disqusTitle":"Once Lethal, Multiple Myeloma May Be In A ‘Golden Age’ Of Treatment","nprByline":"Karen Weintraub\u003cbr />STAT","path":"/futureofyou/442147/once-lethal-multiple-myeloma-may-be-in-a-golden-age-of-treatment","audioTrackLength":null,"parsedContent":[{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003cp>If you can call someone who gets a rare form of cancer lucky, then Deb Graff says she fits the bill.\u003c/p>\u003cp>\u003c/p>\u003cp>\u003c/p>\n\u003cp>At age 72, Graff has survived nine years with multiple myeloma, a blood cancer whose life expectancy used to be measured in months.\u003c/p>\n\u003cp>“I wasn’t ready to go anywhere,” said Graff, who lives in South Dennis, Mass., on Cape Cod. “I wanted to see my grandkids grow up and still be an aggravation to my husband.”\u003c/p>\n\u003cp>She was lucky enough to get multiple myeloma after the 2003 release of a drug called Velcade (bortezomib), one of the first therapies to directly target multiple myeloma. Velcade, plus more than 20 other approvals since then, have transformed multiple myeloma care. For three-quarters of patients, a disease that once brought a three-year life expectancy has become a long-term, chronic illness.\u003c/p>\n\u003cp>Now, multiple myeloma is poised for another inflection point.\u003c/p>\n\u003cp>\u003c/p>\u003c/div>","attributes":{"named":{},"numeric":[]}},{"type":"component","content":"","name":"ad","attributes":{"named":{"label":"fullwidth"},"numeric":["fullwidth"]}},{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003c/p>\n\u003cp>There are 89 experimental drugs currently being tested in people, according to Biomedtracker, a research unit of Informa. Some are improvements on existing drugs, others have found new ways to target the cancer cells; a few engage the body’s immune system in the fight.\u003c/p>\n\u003cp>Not all the drugs will make it through the trial process, of course.\u003c/p>\n\u003cp>But on the roster, there may be effective treatments for the one-quarter of patients who haven’t yet been helped by existing drugs. There may be regimens that are less challenging than the daily pills, regular infusions, and frequent doctor’s appointments that Graff and others have to manage. And there may be the long-sought cure.\u003c/p>\u003cp>\u003c/p>\u003cp>\u003c/p>\n\u003cp>“There’s no question it’s a golden age in multiple myeloma drug development,” said Dr. David Reese, a senior vice president at Amgen, which developed the drug Kyprolis (carfilzomib), and is testing five others.\u003c/p>\n\u003cp>“It’s possible that we already are at the juncture where patients diagnosed with this disease could live with this disease for the rest of their lives,” added Dr. Ola Landgren, chief of the Multiple Myeloma Service at Memorial Sloan Kettering Cancer Center in New York.\u003c/p>\n\u003cp>Despite all the advances and optimism, though, most patients with multiple myeloma will still die of multiple myeloma.\u003c/p>\n\u003cp>“It is incurable. I think it is a mistake to suggest otherwise,” said Dr. Paul Richardson, Graff’s physician at the Dana-Farber Cancer Institute in Boston. “I think that this disease is forever humbling.”\u003c/p>\n\u003cp>Every multiple myeloma patient’s disease takes a different path. That makes it hard to understand and even harder to predict.\u003c/p>\n\u003cp>The cancer starts in a subgroup of white blood cells called plasma cells that normally make antibodies to fight infection. When cancerous, these plasma cells produce abnormal proteins that damage organs. But where they wreak havoc can vary from person to person.\u003c/p>\n\u003cp>Many patients suffer crushing fatigue, aching joints, and broken bones. Some get bounced around from one doctor to the next before finally getting a diagnosis.\u003c/p>\n\u003cp>Graff, though, never had a symptom. In late 2009, she went in for a routine physical. She and her husband had just retired, sold their house, and were headed to North Carolina. Ten days after the move, Graff’s primary care doctor back in Massachusetts called and said she’d like to run another blood test.\u003c/p>\n\u003cp>\u003c/p>\u003c/div>","attributes":{"named":{},"numeric":[]}},{"type":"component","content":"","name":"ad","attributes":{"named":{"label":"floatright"},"numeric":["floatright"]}},{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003c/p>\n\u003cp>After her diagnosis and a genetic screen, Graff got more bad news. Her cancer included a genetic mutation called a 17p deletion “that was kind of the kiss of death,” Graff said. Every drug trial she looked at showed positive results for all patients, Graff said, except for those with 17p deletions.\u003c/p>\n\u003cdiv class=\"quote\">\n\u003cdiv class=\"quote-inner\">\n\u003cp>Graff’s younger daughter moved up her wedding to Memorial Day 2010 to make sure her mother could attend. Graff was scheduled for a stem cell transplant six weeks later.\u003c/p>\u003cp>\u003c/p>\u003cp>\u003c/p>\n\u003cp>Unfortunately, like many people with a 17p deletion, the transplant didn’t stick. Instead of staying in remission, by November 2010, she was put on a cocktail of three powerful drugs.\u003c/p>\n\u003cp>With so many approved therapies, doctors like Graff’s can keep switching their patients’ regimens. If one combination stops working, there’s another one to try.\u003c/p>\n\u003cp>“My feeling, and I think it was the right feeling, was that it was my job to stay alive and Paul’s job was to find the next best thing,” she said, referring to her doctor.\u003c/p>\n\u003cp>But still, the disease is tenacious.\u003c/p>\n\u003cp>“It will come back even after remission of five to 10 years,” said Dr. Elisabet Manasanch, an assistant professor in the department of lymphoma/myeloma at the University of Texas MD Anderson Cancer Center in Houston.\u003c/p>\n\u003cdiv class=\"quote\">\n\u003cdiv class=\"quote-inner\">\n\u003cp>There’s no such thing as too many treatment options with a disease as wily as multiple myeloma.\u003c/p>\n\u003cp>“Maybe 1,000 drugs is not enough,” said Martina Sersch, Amgen’s head of global development oncology. “It’s a very clever disease.”\u003c/p>\n\u003cp>And now that patients are living longer, the quality of that extra time matters more, Landgren of Memorial Sloan Kettering said, adding that he expects the next wave of therapies will improve the patient experience.\u003c/p>\n\u003cp>Amgen’s drug Kyprolis, for instance, is currently given twice a week via infusion, but is being tested at a higher, once-a-week dose. Trial results for this regimen will be presented at the American Society for Clinical Oncology annual meeting, which starts Friday.\u003c/p>\n\u003cp>“We may have to attack it from different sides and different pathways to achieve what we ultimately want to achieve, which is a functional cure,” Sersch said.\u003c/p>\n\u003cp>Most patients today start with a combination of treatments: a “veritable Army, Navy, and Air Force,” as Richardson puts it.\u003c/p>\n\u003cp>They get a proteasome inhibitor, often Velcade, to directly attack the myeloma cells; an immunomodulatory treatment such as Revlimid (lenalidomide); and the steroid dexamethasone to tamp down an over-reactive immune system.\u003c/p>\n\u003c/div>\n\u003c/div>\n\u003cp>The Marines, Richardson said, are also coming, in the form of monoclonal antibodies, a type of engineered protein that can bind specifically to cancer cells.\u003c/p>\n\u003cp>The monoclonal antibody\u003csup> \u003c/sup>daratumumab, sold by the Janssen unit of Johnson & Johnson under the brand name Darzalex, was first approved in 2015 for people with late-stage disease. Earlier this month, the Food and Drug Administration \u003ca href=\"https://www.jnj.com/media-center/press-releases/janssen-announces-darzalex-daratumumab-us-fda-approval-for-newly-diagnosed-patients-with-multiple-myeloma-who-are-transplant-ineligible\" target=\"_blank\" rel=\"noopener\">expanded\u003c/a> its approval, allowing it to be used in combination with the standard, three-pronged treatment in newly diagnosed patients.\u003c/p>\u003cp>\u003c/p>\u003cp>\u003c/p>\n\u003cp>Daratumumab seeks out, binds to, and preferentially kills multiple myeloma cells. In a company-supported study published in the \u003ca href=\"https://www.nejm.org/doi/full/10.1056/NEJMoa1714678?query=featured_home%20-\" target=\"_blank\" rel=\"noopener\">New England Journal of Medicine\u003c/a> in February, 22 percent of patients who used the four-drug combination showed undetectable levels of disease after about 16.5 months. Only 6 percent of patients who used the three-drug combination saw such results.\u003c/p>\n\u003cp>“If you can fundamentally clear all the disease from a patient, now you start to think about, wow — maybe I can get to cure,” said Mark Wildgust, vice president for global medical affairs, oncology, at Janssen.\u003c/p>\n\u003cp>Today’s drugs are so effective that studies take a very long time. In one trial for Kyprolis, for instance, patients who were supposed to be near the end of life survived for 48 months on average, Amgen’s Sersch said. Drug companies will need to find strong, validated criteria other than survival, she said, to provide faster results and potentially drug approvals.\u003c/p>\n\u003cp>Amgen is hoping for game-changing responses to an experimental type of treatment called a BiTE — for bispecific T cell engager. BiTEs essentially are two-armed drugs, Reese said. One arm grabs the tumor cell and the other an immune cell. This activates the immune cell, which kills the cancer cell and primes the immune system to turn against others.\u003c/p>\n\u003cp>It’s too soon to know how long a patient would need to be on BiTE therapy, how to identify which patients might be helped, or how much improvement to expect, Reese said. But because BiTEs train the immune system to fight cancer, they might offer the possibility of a long-term remission or even a cure.\u003c/p>\n\u003cp>Other immune therapies under development include vaccines to amp up the immune system, and an approach called CAR-T, for chimeric antigen receptor T cell. In CAR-T, a patient’s own immune cells are removed and engineered to track down and destroy tumor cells.\u003c/p>\n\u003cp>Richardson, whose first multiple myeloma patient back in 1986 survived just three months, said he’s been amazed by how well CAR-Ts have worked in some of his sickest patients.\u003c/p>\n\u003cp>“I’ve seen the most dramatic responses in CAR-T. They’re quite remarkable,” he said. “Patients who’ve been so ill, and these therapies really made a difference for them beyond what I would expect.”\u003c/p>\n\u003cp>Because CAR-Ts have to be made with the patient’s own T cells, they are expensive and time-consuming; BiTEs are off the shelf and can be mass-produced, theoretically at a lower cost.\u003c/p>\n\u003cfigure id=\"attachment_341074\" class=\"media media-align-center media-break\">\u003ca href=\"https://www.statnews.com/wp-content/uploads/2018/05/multiplemyeloma_01.jpg\">\u003cimg class=\"media-content wp-image-341074 size-large aligncenter\" src=\"https://www.statnews.com/wp-content/uploads/2018/05/multiplemyeloma_01-1024x683.jpg\" alt=\"Multiple Myeloma 03\" width=\"1024\" height=\"683\">\u003c/a>\u003c/figure>\n\u003cp>Cost, of course, is another huge issue in multiple myeloma therapy.\u003c/p>\n\u003cp>Lisa Stephenson, 65, of Whitefish, Mont., who was diagnosed in June 2014, said her multidrug regimen runs about $29,000 a month, plus an occasional $7,000 to boost her immune system. Luckily, nearly all of it is covered by the “incredible insurance” from the law firm where her husband worked until his recent retirement.\u003c/p>\n\u003cp>Stephenson didn’t end up needing a stem cell transplant because an experimental therapy she took at the beginning of her treatment worked so well. But if she had needed it — or needs one in the future — she was told it would cost a minimum of $365,000.\u003c/p>\n\u003cp>“I think to myself, ‘How in the world can people who don’t have good insurance — what do they do?’” she said.\u003c/p>\n\u003cp>It’s not yet clear how much the experimental therapies like BiTEs will cost patients, Amgen’s Reese said. But if these new treatments can produce truly life-altering results, then a one-time large payment, as seen recently with \u003ca href=\"https://www.statnews.com/2018/01/03/spark-gene-therapy-price/\" target=\"_blank\" rel=\"noopener\">gene therapy\u003c/a> and \u003ca href=\"https://www.statnews.com/2017/08/30/novartis-car-t-cancer-approved/\" target=\"_blank\" rel=\"noopener\">CAR-Ts in other types\u003c/a> of blood cancer, might be justifiable. Or, as Wildgust from Janssen put it, “if we can eliminate disease, I’m sure we’ll be able to find a value proposition.”\u003c/p>\u003cp>\u003c/p>\u003cp>\u003c/p>\n\u003cp>Stephenson and Graff both said that they still feel like patients much of the time, and that every ache and pain can awaken cancer fears. But they are endlessly grateful for the years the treatments have given them.\u003c/p>\n\u003cp>“Life is good. I can’t complain,” said Stephenson, a mother of three with a strong religious faith. “As bad as myeloma is — and it hasn’t been a picnic by any means — but it has brought so many silver linings. To list them all would take all day.”\u003c/p>\n\u003cp>She doesn’t sweat the small stuff anymore.\u003c/p>\n\u003cp>“So what if you reach for a can of crushed tomatoes and you don’t have any — it’s not the end of the world. Or your stove is dirty. So? I’ll clean it tomorrow if I don’t want to do it today.”\u003c/p>\n\u003cp>Both she and Graff spend time sharing what they’ve learned with patients who are coming up behind them.\u003c/p>\n\u003cp>“I tell people how lucky they are to be diagnosed with multiple myeloma at this time,” said Graff, whose youngest granddaughters are now 4 and 6. “If you have to have it, this is the time.”\u003c/p>\n\u003cdiv class=\"content-meta\"> \u003cem>This \u003ca href=\"https://www.statnews.com/2018/05/29/multiple-myeloma-drug-development/\" target=\"_blank\" rel=\"noopener\">story\u003c/a> was originally published by STAT, an online publication of Boston Globe Media that covers health, medicine, and scientific discovery.\u003c/em>\u003c/div>\n\u003c/div>\n\u003c/div>\n\n\u003c/div>\u003c/p>","attributes":{"named":{},"numeric":[]}}],"link":"/futureofyou/442147/once-lethal-multiple-myeloma-may-be-in-a-golden-age-of-treatment","authors":["byline_futureofyou_442147"],"categories":["futureofyou_1","futureofyou_73"],"tags":["futureofyou_103","futureofyou_1225","futureofyou_61","futureofyou_1507"],"featImg":"futureofyou_442150","label":"futureofyou"},"futureofyou_357754":{"type":"posts","id":"futureofyou_357754","meta":{"index":"posts_1591205157","site":"futureofyou","id":"357754","score":null,"sort":[1490825713000]},"guestAuthors":[],"slug":"common-blood-tests-may-help-predict-chronic-disease-risk","title":"Common Blood Tests May Help Predict Chronic Disease Risk","publishDate":1490825713,"format":"standard","headTitle":"KQED Future of You | KQED Science","labelTerm":{"site":"futureofyou"},"content":"\u003cp>A score based on common blood tests may someday help people gauge their risk of developing a chronic disease like diabetes or dementia within three years of taking the test.\u003c/p>\n\u003cp>The Intermountain Chronic Disease Risk Score was 77 to 78 percent accurate in predicting whether someone would be diagnosed with diabetes, kidney failure, coronary artery disease and dementia, among other illnesses. It's based on the results of a \u003ca href=\"https://medlineplus.gov/ency/article/003468.htm\">comprehensive metabolic panel\u003c/a>, which includes tests for blood glucose and liver function, and \u003ca href=\"https://medlineplus.gov/bloodcounttests.html#summary\">complete blood count\u003c/a>, which measures the quantity of different types of blood cells.\u003c/p>\n\u003caside class=\"pullquote alignright\">'They may be on to something, but it’s too early to say for sure.'\u003ccite>Wayne Dysinger,\u003cbr>\nLifestyle Medicine Solutions\u003c/cite>\u003c/aside>\n\u003cp>The hope is that the score could eventually help physicians better allocate their time and resources, says \u003ca href=\"https://intermountainhealthcare.org/services/heart-care/heart-institute/research-and-clinical-trials/research-team/epidemiologists/heidi-may/\">Heidi May\u003c/a>, a cardiovascular epidemiologist with the Intermountain Medical Center Heart Institute in Salt Lake City, and principal investigator of the study. For example, a patient whose score puts her in the high-risk group might get more intense patient education about lifestyle or other prevention measures, and a follow-up visit in six months rather than a year.\u003c/p>\n\u003cp>The tests used in the score are commonly performed at checkups, and the score itself can be calculated by the hospital's electronic health record, making it easier for doctors to use. \"Clinicians are so busy and have to worry about so many things,\" says May. The so-called ICHRON score is similar to \u003ca href=\"https://intermountainhealthcare.org/about/transforming-healthcare/innovation/intermountain-risk-scores/risk-scores/\">risk scores\u003c/a> previously developed and now used by Intermountain Healthcare, a nonprofit hospital system, to predict the future risk of death, hospital readmission and serious disease.\u003c/p>\n\u003cp>The research was presented last month at a meeting of the American College of Cardiology.\u003c/p>\n\u003cp>[ad fullwidth]\u003c/p>\n\u003cp>\"It's a fascinating concept,\" says \u003ca href=\"http://provider.kareo.com/dr-wayne-dysinger-1\">Wayne Dysinger\u003c/a>, a preventive and family medicine physician and CEO of Lifestyle Medicine Solutions, a primary care practice in southern California, who wasn't involved in the study. \"They may be on to something, but it's too early to say for sure.\"\u003c/p>\n\u003cp>[contextly_sidebar id=\"4FJC8XHrFm7lnXNkyhtLENB2eXu8G8oh\"]For one thing, the score would have to be shown to be accurate in a more general population outside Utah, which is largely white and has lower rates of smoking and obesity than other states.\u003c/p>\n\u003cp>The score was developed based on the data in one group of primary care patients and then tested again in another group, and it is gender-specific. Among the more than 144,000 patients studied, 7 percent of women and 9 percent of men were diagnosed with at least one chronic disease in the next three years, most commonly diabetes or coronary artery disease.\u003c/p>\n\u003cp>Among women, those with a high ICHRON score were 11 times more likely to be diagnosed with a chronic disease than those with a low score. Women with a moderate score were three times more likely to be diagnosed. Men with a high score were 14 times more likely to be diagnosed than those with a low score, and those with a moderate score more than five times more likely to be diagnosed.\u003c/p>\n\u003cp>Dysinger notes the prediction isn't perfect, and that people don't have to wait to be identified as at-risk to change their lifestyle, starting with turning away from processed foods to whole foods. \u003ca href=\"http://www.who.int/chp/chronic_disease_report/part1/en/index11.html\">According to the World Health Organization\u003c/a>, 80 percent of premature heart disease, stroke and diabetes can be prevented through lifestyle measures like avoiding tobacco use, keeping weight at a healthy level and exercise.\u003c/p>\n\u003cp>\u003c/p>\n\u003cp>\u003cem>Katherine Hobson is a freelance health and science writer based in Brooklyn, N.Y. She's on Twitter: \u003c/em>\u003ca href=\"https://twitter.com/katherinehobson\">\u003cem>@katherinehobson\u003c/em>\u003c/a>\u003cem>.\u003c/em>\u003c/p>\n\u003cdiv class=\"fullattribution\">\n\u003cp>Copyright 2017 \u003ca href=\"http://www.npr.org\" target=\"_blank\">NPR\u003c/a>.\u003c/p>\n\u003c/div>\n\n","blocks":[],"excerpt":"The risk assessment score may help primary care physicians better identify patients who need extra counseling and follow-up.","status":"publish","parent":0,"modified":1491321178,"stats":{"hasAudio":false,"hasVideo":false,"hasChartOrMap":false,"iframeSrcs":[],"hasGoogleForm":false,"hasGallery":false,"hasHearkenModule":false,"hasPolis":false,"paragraphCount":14,"wordCount":603},"headData":{"title":"Common Blood Tests May Help Predict Chronic Disease Risk | KQED","description":"The risk assessment score may help primary care physicians better identify patients who need extra counseling and follow-up.","ogTitle":"","ogDescription":"","ogImgId":"","twTitle":"","twDescription":"","twImgId":"","schema":{"@context":"http://schema.org","@type":"Article","headline":"Common Blood Tests May Help Predict Chronic Disease Risk","datePublished":"2017-03-29T22:15:13.000Z","dateModified":"2017-04-04T15:52:58.000Z","image":"https://cdn.kqed.org/wp-content/uploads/2020/02/KQED-OG-Image@1x.png"}},"disqusIdentifier":"357754 https://ww2.kqed.org/futureofyou/?p=357754","disqusUrl":"https://ww2.kqed.org/futureofyou/2017/03/29/common-blood-tests-may-help-predict-chronic-disease-risk/","disqusTitle":"Common Blood Tests May Help Predict Chronic Disease Risk","nprImageCredit":"Martynasfoto","nprByline":"\u003cstrong>Katherine Hobson\u003cbr />NPR Shots\u003c/strong>","nprImageAgency":"Getty Images/iStockphoto","nprStoryId":"520437040","nprApiLink":"http://api.npr.org/query?id=520437040&apiKey=MDAxOTAwOTE4MDEyMTkxMDAzNjczZDljZA004","nprHtmlLink":"http://www.npr.org/sections/health-shots/2017/03/17/520437040/common-blood-tests-can-help-predict-chronic-disease-risk?ft=nprml&f=520437040","nprRetrievedStory":"1","nprPubDate":"Fri, 17 Mar 2017 14:46:00 -0400","nprStoryDate":"Fri, 17 Mar 2017 10:20:00 -0400","nprLastModifiedDate":"Fri, 17 Mar 2017 14:46:35 -0400","path":"/futureofyou/357754/common-blood-tests-may-help-predict-chronic-disease-risk","audioTrackLength":null,"parsedContent":[{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003cp>A score based on common blood tests may someday help people gauge their risk of developing a chronic disease like diabetes or dementia within three years of taking the test.\u003c/p>\n\u003cp>The Intermountain Chronic Disease Risk Score was 77 to 78 percent accurate in predicting whether someone would be diagnosed with diabetes, kidney failure, coronary artery disease and dementia, among other illnesses. It's based on the results of a \u003ca href=\"https://medlineplus.gov/ency/article/003468.htm\">comprehensive metabolic panel\u003c/a>, which includes tests for blood glucose and liver function, and \u003ca href=\"https://medlineplus.gov/bloodcounttests.html#summary\">complete blood count\u003c/a>, which measures the quantity of different types of blood cells.\u003c/p>\n\u003caside class=\"pullquote alignright\">'They may be on to something, but it’s too early to say for sure.'\u003ccite>Wayne Dysinger,\u003cbr>\nLifestyle Medicine Solutions\u003c/cite>\u003c/aside>\n\u003cp>The hope is that the score could eventually help physicians better allocate their time and resources, says \u003ca href=\"https://intermountainhealthcare.org/services/heart-care/heart-institute/research-and-clinical-trials/research-team/epidemiologists/heidi-may/\">Heidi May\u003c/a>, a cardiovascular epidemiologist with the Intermountain Medical Center Heart Institute in Salt Lake City, and principal investigator of the study. For example, a patient whose score puts her in the high-risk group might get more intense patient education about lifestyle or other prevention measures, and a follow-up visit in six months rather than a year.\u003c/p>\n\u003cp>The tests used in the score are commonly performed at checkups, and the score itself can be calculated by the hospital's electronic health record, making it easier for doctors to use. \"Clinicians are so busy and have to worry about so many things,\" says May. The so-called ICHRON score is similar to \u003ca href=\"https://intermountainhealthcare.org/about/transforming-healthcare/innovation/intermountain-risk-scores/risk-scores/\">risk scores\u003c/a> previously developed and now used by Intermountain Healthcare, a nonprofit hospital system, to predict the future risk of death, hospital readmission and serious disease.\u003c/p>\n\u003cp>The research was presented last month at a meeting of the American College of Cardiology.\u003c/p>\n\u003cp>\u003c/p>\u003c/div>","attributes":{"named":{},"numeric":[]}},{"type":"component","content":"","name":"ad","attributes":{"named":{"label":"fullwidth"},"numeric":["fullwidth"]}},{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003c/p>\n\u003cp>\"It's a fascinating concept,\" says \u003ca href=\"http://provider.kareo.com/dr-wayne-dysinger-1\">Wayne Dysinger\u003c/a>, a preventive and family medicine physician and CEO of Lifestyle Medicine Solutions, a primary care practice in southern California, who wasn't involved in the study. \"They may be on to something, but it's too early to say for sure.\"\u003c/p>\n\u003cp>\u003c/p>\u003cp>\u003c/p>\u003cp>For one thing, the score would have to be shown to be accurate in a more general population outside Utah, which is largely white and has lower rates of smoking and obesity than other states.\u003c/p>\n\u003cp>The score was developed based on the data in one group of primary care patients and then tested again in another group, and it is gender-specific. Among the more than 144,000 patients studied, 7 percent of women and 9 percent of men were diagnosed with at least one chronic disease in the next three years, most commonly diabetes or coronary artery disease.\u003c/p>\n\u003cp>Among women, those with a high ICHRON score were 11 times more likely to be diagnosed with a chronic disease than those with a low score. Women with a moderate score were three times more likely to be diagnosed. Men with a high score were 14 times more likely to be diagnosed than those with a low score, and those with a moderate score more than five times more likely to be diagnosed.\u003c/p>\n\u003cp>Dysinger notes the prediction isn't perfect, and that people don't have to wait to be identified as at-risk to change their lifestyle, starting with turning away from processed foods to whole foods. \u003ca href=\"http://www.who.int/chp/chronic_disease_report/part1/en/index11.html\">According to the World Health Organization\u003c/a>, 80 percent of premature heart disease, stroke and diabetes can be prevented through lifestyle measures like avoiding tobacco use, keeping weight at a healthy level and exercise.\u003c/p>\n\u003cp>\u003c/p>\n\u003cp>\u003cem>Katherine Hobson is a freelance health and science writer based in Brooklyn, N.Y. She's on Twitter: \u003c/em>\u003ca href=\"https://twitter.com/katherinehobson\">\u003cem>@katherinehobson\u003c/em>\u003c/a>\u003cem>.\u003c/em>\u003c/p>\n\u003cdiv class=\"fullattribution\">\n\u003cp>Copyright 2017 \u003ca href=\"http://www.npr.org\" target=\"_blank\">NPR\u003c/a>.\u003c/p>\n\u003c/div>\n\n\u003c/div>\u003c/p>","attributes":{"named":{},"numeric":[]}}],"link":"/futureofyou/357754/common-blood-tests-may-help-predict-chronic-disease-risk","authors":["byline_futureofyou_357754"],"categories":["futureofyou_1"],"tags":["futureofyou_164","futureofyou_1225"],"featImg":"futureofyou_357755","label":"futureofyou"},"futureofyou_1118":{"type":"posts","id":"futureofyou_1118","meta":{"index":"posts_1591205157","site":"futureofyou","id":"1118","score":null,"sort":[1427986816000]},"guestAuthors":[],"slug":"why-smart-clothing-is-the-next-frontier-for-wearable-health-tech","title":"Why “Smart Clothing” is the Next Frontier for Wearable Health Tech","publishDate":1427986816,"format":"standard","headTitle":"Future of You | KQED Future of You | KQED Science","labelTerm":{"term":54,"site":"futureofyou"},"content":"\u003cp>When Eric Blue goes to the gym, he sports a wafer-thin shirt that tracks his every move.\u003c/p>\n\u003cp>Blue’s shirt contains tiny sensors, which are woven into the fabric. They monitor his heart rate, the calories he burns and other metrics, like breathing rate. And a companion mobile app on his smart phone informs him about the intensity of his workouts.\u003c/p>\n\u003cp>Blue, a Los Angeles entrepreneur, says regular use of the shirt has pushed him to “up his game” during exercise.\u003c/p>\n\u003cp>This is no ordinary shirt. It represents the evolution of the wearable-tech trend from accessories, like watches and bands like Fitbits, to full-blown clothing.\u003c/p>\n\u003cp>Blue, 38, was among the first people to buy a biometric shirt from Montreal-based startup \u003ca href=\"http://www.hexoskin.com/\">Hexoskin\u003c/a>. Blue is a self-professed “fitness junkie” who goes to the gym at least five times each week, so he said the shirt is worth the $399 price tag. For Blue, it’s far easier to throw on a Hexoskin shirt and go, rather than fiddle with a smartphone or chest strap.\u003c/p>\n\u003cp>[ad fullwidth]\u003c/p>\n\u003cp>\"My old heart rate monitor is now sitting in the closet, gathering dust,\" he said.\u003c/p>\n\u003cfigure id=\"attachment_1121\" class=\"wp-caption alignright\" style=\"max-width: 751px\">\u003cimg class=\"size-full wp-image-1121\" src=\"http://ww2.kqed.org/futureofyou/wp-content/uploads/sites/13/2015/04/gym_01.jpg\" alt=\"Gym-goers wearing gear from Hexoskin\" width=\"751\" height=\"500\" srcset=\"https://ww2.kqed.org/app/uploads/sites/13/2015/04/gym_01.jpg 751w, https://ww2.kqed.org/app/uploads/sites/13/2015/04/gym_01-400x266.jpg 400w, https://ww2.kqed.org/app/uploads/sites/13/2015/04/gym_01-320x213.jpg 320w\" sizes=\"(max-width: 751px) 100vw, 751px\">\u003cfigcaption class=\"wp-caption-text\">Gym-goers wearing gear from Hexoskin \u003ccite>(Hexoskin)\u003c/cite>\u003c/figcaption>\u003c/figure>\n\u003cp class=\"p1\">\u003cspan class=\"s1\">\"It sounds very sci-fi right now, but in\u003c/span> the future all of the personal data being collected by health and fitness sensors and smart watches will alternatively be readily available in our clothing.\"\u003c/p>\n\u003cp>Blue isn’t alone in embracing the smart clothing trend.\u003c/p>\n\u003cp>Famous athletes, \u003ca href=\"http://www.space.com/28945-mock-mars-mission-hexoskin-shirt.html\">astronauts\u003c/a>, and even \u003ca href=\"http://www.hexoskin.com/blogs/news/13604554-cirque-du-soleil-uses-hexoskin-to-monitor-performers-fatigue\">Cirque du Soleil performers\u003c/a> have all espoused the benefits of using Hexoskin and other smart clothing products. Smart shirts, athletic pants and even socks started hitting stores last year.\u003c/p>\n\u003cp>But medical experts say they hope patients with serious and chronic conditions also can benefit from smart clothing. When will these products reach the health care market, where they may be needed most?\u003c/p>\n\u003cp>“These companies will hit fitness fans first,” said Stephanie Tilenius, founder of \u003ca href=\"https://www.vida.com/\">Vida\u003c/a>, a mobile app that matches sick patients with personal health coaches.\u003c/p>\n\u003cp>“But I see huge potential for chronic care.”\u003c/p>\n\u003cp>\u003cstrong>Rapid Evolution\u003c/strong>\u003c/p>\n\u003cp>It’s still early for smart clothing, but the technology is evolving rapidly.\u003c/p>\n\u003cp>One company, \u003ca href=\"http://www.liveathos.com/\">Athos\u003c/a>, based in Redwood City, develops garments that can track people’s muscles as they move. Sensors in its shirt can detect whether a user is putting too much pressure on one side of the body, for instance.\u003c/p>\n\u003cp>Athos is focused on reaching passionate exercisers who want to make improvements to their exercise regimes, like training more intensively while avoiding injury, said CEO Dhananja Jayalath.\u003c/p>\n\u003cp>\"The people who buy our stuff are into fitness -- they typically spent a lot of time working out,\" he said.\u003c/p>\n\u003cp>As is the case with many startups, Jayalath started Athos to solve a personal problem.\u003c/p>\n\u003caside class=\"pullquote alignright\">“My old heart rate monitor is now sitting in the closet, gathering dust.'\"\u003cbr>\n\u003ccite>Eric Blue, Hexoskin user and the founder of Traqs\u003c/cite>\u003c/aside>\n\u003cp>He came up with the idea while studying electrical engineering in college. Jayalath, who frequently goes to the gym, said he couldn’t stop thinking about whether technology could replace a personal trainer.\u003c/p>\n\u003cp>“After we came up with the idea, people told us we were crazy and it wasn’t possible,” he said.\u003c/p>\n\u003cp>It took Jayalath and a fellow electrical engineer just five years to build a working prototype.\u003c/p>\n\u003cp>Against all expectations, Jayalath succeeded in developing apparel that can track muscle activity, heart rate recovery times and breathing rates. In the past, athletes would have needed to be hooked up to a machine in a performance lab to access this information.\u003c/p>\n\u003cp>Jayalath didn’t intend to build a product for sick people. But Athos has already received a great deal of interest from the medical community.\u003c/p>\n\u003cp>The company anticipates that its clothing will eventually be used in all kinds of clinical settings, such as hospitals and rehabilitation clinics. Smart clothing could benefit patients with a variety of medical conditions, including heart disease and obesity.\u003c/p>\n\u003cp>“Gradually over the next few years, these low-cost, consumer-focused, data-rich devices and apps will bring to bear vastly more data than physicians have in some circumstances,” said Pete Moran, a general partner at the venture capital firm \u003ca href=\"http://www.dcm.com/\">DCM\u003c/a>, which invested in Athos.\u003c/p>\n\u003cp>But selling to hospitals comes with strings attached.\u003c/p>\n\u003cp>“It would be far easier for a product like this to remain in the ‘wellness’ category,” said Morgan Reed, an executive director at \u003ca href=\"http://actonline.org/\">The App Association\u003c/a>, a Washington, D.C. nonprofit that works with patient advocates and app developers.\u003c/p>\n\u003cp>By saying they are helping improve fitness and well being, Reed said, these companies may hope to avoid regulatory oversight from government agencies like the U.S. Food and Drug Administration.\u003c/p>\n\u003cp>\u003cstrong>Smart Training to Smart Recovery\u003c/strong>\u003c/p>\n\u003cp>NBA All-Star Jermaine O’Neal \u003ca href=\"http://www.bizjournals.com/sanjose/news/2014/08/12/nbas-jermaine-oneal-joe-lacob-join-12-2m-funding.html?page=all\">recently endorsed and made a personal investment in\u003c/a> Athos because it helps him \"train smarter.\"\u003c/p>\n\u003cp>But how about helping surgical patients recover smarter?\u003c/p>\n\u003cp>“Fitness shirts could find a market in rehabilitation and could facilitate home exercises. That's just a thought,” said Dr. Molly Maloof, a general practitioner based in San Francisco, who has been closely following the wearable tech trend.\u003c/p>\n\u003caside class=\"pullquote alignleft\">\"There has been an explosion in patient-generated data, but much of it may not be useful to physicians in the short-term.\"\u003cbr>\n\u003ccite>Dr. Pat Basu,chief medical officer at Doctor On Demand\u003c/cite>\u003c/aside>\n\u003cp>Patients could wear biometric shirts and other apparel after surgeries, she said. Those who have recently undergone cardiac surgery, for instance, could be alerted if their heart rate is too high.\u003c/p>\n\u003cp>Smart clothing might also help people who are obese or overweight. Some doctors would consider recommending smart clothing to some of their patients, if it would inspire them to exercise regularly.\u003c/p>\n\u003cp>\"The fact is that the majority of Americans are in terrible shape,\" said Maloof. According to Maloof, fitness shirts could help get people on their feet, as long as the product proves to be more compelling than a barely-used gym membership.\u003c/p>\n\u003cp>Other physicians said they remain unconvinced that the data is precise. This mistrust doesn’t just apply to smart clothing, but the wearable-tech trend in general.\u003c/p>\n\u003cp>“There has been an explosion in patient-generated data, but much of it may not be useful to physicians in the short-term,” said Dr. Pat Basu, a former chief resident at Stanford University and current chief medical officer at \u003ca href=\"http://www.doctorondemand.com/\">Doctor On Demand\u003c/a>, an app that connects people to doctors.\u003c/p>\n\u003cp>“If a patient is showing me their blood pressure or heart rate they gathered from an app or device, I’ll always ask myself, ‘Is the fidelity of this information accurate or not?'”\u003c/p>\n\u003cp>Basu also said that wearable-tech makers should produce reports about each patient that doctors and nurses can skim. Many physicians are already inundated with the wealth of data that patients are generating from new wearable apps and devices, he said.\u003c/p>\n\u003cp>Moreover, some doctors fear that they will be liable if they miss something in the growing pile of patient data.\u003c/p>\n\u003cp>Privacy is another concern. The App Association’s executive director, Morgan Reed, has examined the privacy policies of companies like Athos.\u003c/p>\n\u003cp>He’s satisfied that patient’s sensitive health information is protected – for now.\u003c/p>\n\u003cp>But Reed expressed fears that the next crop of smart clothing companies might opt to offset the high cost of their products by selling people’s health data to pharmaceutical companies, insurance providers and even employers.\u003c/p>\n\u003cp>\u003ca href=\"http://www.fiercemobilehealthcare.com/story/senator-wants-ftc-rules-data-selling-wearable-device-companies/2014-08-11\">Fears are mounting among policymakers \u003c/a>that many of the most popular wearable tech companies are selling people’s personal health data, including step counts, hours of sleep and location.\u003c/p>\n\u003cp>[ad floatright]\u003c/p>\n\u003cp>“Would consumers understand that they’re buying the version that is monetizing through data-sharing?” Reed said. “That’s the problem that everyone in the wearables industry is working on right now.”\u003c/p>\n\n","blocks":[],"excerpt":"The wearable-technology trend is quickly evolving from accessories, like bands, to full-on clothing. Unlike Fitbits, \"smart\" clothing can track everything from your muscle activity to your heart rate.","status":"publish","parent":0,"modified":1517014624,"stats":{"hasAudio":false,"hasVideo":false,"hasChartOrMap":false,"iframeSrcs":[],"hasGoogleForm":false,"hasGallery":false,"hasHearkenModule":false,"hasPolis":false,"paragraphCount":46,"wordCount":1348},"headData":{"title":"Why “Smart Clothing” is the Next Frontier for Wearable Health Tech | KQED","description":"The wearable-technology trend is quickly evolving from accessories, like bands, to full-on clothing. Unlike Fitbits, "smart" clothing can track everything from your muscle activity to your heart rate.","ogTitle":"","ogDescription":"","ogImgId":"","twTitle":"","twDescription":"","twImgId":"","schema":{"@context":"http://schema.org","@type":"Article","headline":"Why “Smart Clothing” is the Next Frontier for Wearable Health Tech","datePublished":"2015-04-02T15:00:16.000Z","dateModified":"2018-01-27T00:57:04.000Z","image":"https://cdn.kqed.org/wp-content/uploads/2020/02/KQED-OG-Image@1x.png"}},"disqusIdentifier":"1118 http://ww2.kqed.org/futureofyou/?p=1118","disqusUrl":"https://ww2.kqed.org/futureofyou/2015/04/02/why-smart-clothing-is-the-next-frontier-for-wearable-health-tech/","disqusTitle":"Why “Smart Clothing” is the Next Frontier for Wearable Health Tech","path":"/futureofyou/1118/why-smart-clothing-is-the-next-frontier-for-wearable-health-tech","audioTrackLength":null,"parsedContent":[{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003cp>When Eric Blue goes to the gym, he sports a wafer-thin shirt that tracks his every move.\u003c/p>\n\u003cp>Blue’s shirt contains tiny sensors, which are woven into the fabric. They monitor his heart rate, the calories he burns and other metrics, like breathing rate. And a companion mobile app on his smart phone informs him about the intensity of his workouts.\u003c/p>\n\u003cp>Blue, a Los Angeles entrepreneur, says regular use of the shirt has pushed him to “up his game” during exercise.\u003c/p>\n\u003cp>This is no ordinary shirt. It represents the evolution of the wearable-tech trend from accessories, like watches and bands like Fitbits, to full-blown clothing.\u003c/p>\n\u003cp>Blue, 38, was among the first people to buy a biometric shirt from Montreal-based startup \u003ca href=\"http://www.hexoskin.com/\">Hexoskin\u003c/a>. Blue is a self-professed “fitness junkie” who goes to the gym at least five times each week, so he said the shirt is worth the $399 price tag. For Blue, it’s far easier to throw on a Hexoskin shirt and go, rather than fiddle with a smartphone or chest strap.\u003c/p>\n\u003cp>\u003c/p>\u003c/div>","attributes":{"named":{},"numeric":[]}},{"type":"component","content":"","name":"ad","attributes":{"named":{"label":"fullwidth"},"numeric":["fullwidth"]}},{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003c/p>\n\u003cp>\"My old heart rate monitor is now sitting in the closet, gathering dust,\" he said.\u003c/p>\n\u003cfigure id=\"attachment_1121\" class=\"wp-caption alignright\" style=\"max-width: 751px\">\u003cimg class=\"size-full wp-image-1121\" src=\"http://ww2.kqed.org/futureofyou/wp-content/uploads/sites/13/2015/04/gym_01.jpg\" alt=\"Gym-goers wearing gear from Hexoskin\" width=\"751\" height=\"500\" srcset=\"https://ww2.kqed.org/app/uploads/sites/13/2015/04/gym_01.jpg 751w, https://ww2.kqed.org/app/uploads/sites/13/2015/04/gym_01-400x266.jpg 400w, https://ww2.kqed.org/app/uploads/sites/13/2015/04/gym_01-320x213.jpg 320w\" sizes=\"(max-width: 751px) 100vw, 751px\">\u003cfigcaption class=\"wp-caption-text\">Gym-goers wearing gear from Hexoskin \u003ccite>(Hexoskin)\u003c/cite>\u003c/figcaption>\u003c/figure>\n\u003cp class=\"p1\">\u003cspan class=\"s1\">\"It sounds very sci-fi right now, but in\u003c/span> the future all of the personal data being collected by health and fitness sensors and smart watches will alternatively be readily available in our clothing.\"\u003c/p>\n\u003cp>Blue isn’t alone in embracing the smart clothing trend.\u003c/p>\n\u003cp>Famous athletes, \u003ca href=\"http://www.space.com/28945-mock-mars-mission-hexoskin-shirt.html\">astronauts\u003c/a>, and even \u003ca href=\"http://www.hexoskin.com/blogs/news/13604554-cirque-du-soleil-uses-hexoskin-to-monitor-performers-fatigue\">Cirque du Soleil performers\u003c/a> have all espoused the benefits of using Hexoskin and other smart clothing products. Smart shirts, athletic pants and even socks started hitting stores last year.\u003c/p>\n\u003cp>But medical experts say they hope patients with serious and chronic conditions also can benefit from smart clothing. When will these products reach the health care market, where they may be needed most?\u003c/p>\n\u003cp>“These companies will hit fitness fans first,” said Stephanie Tilenius, founder of \u003ca href=\"https://www.vida.com/\">Vida\u003c/a>, a mobile app that matches sick patients with personal health coaches.\u003c/p>\n\u003cp>“But I see huge potential for chronic care.”\u003c/p>\n\u003cp>\u003cstrong>Rapid Evolution\u003c/strong>\u003c/p>\n\u003cp>It’s still early for smart clothing, but the technology is evolving rapidly.\u003c/p>\n\u003cp>One company, \u003ca href=\"http://www.liveathos.com/\">Athos\u003c/a>, based in Redwood City, develops garments that can track people’s muscles as they move. Sensors in its shirt can detect whether a user is putting too much pressure on one side of the body, for instance.\u003c/p>\n\u003cp>Athos is focused on reaching passionate exercisers who want to make improvements to their exercise regimes, like training more intensively while avoiding injury, said CEO Dhananja Jayalath.\u003c/p>\n\u003cp>\"The people who buy our stuff are into fitness -- they typically spent a lot of time working out,\" he said.\u003c/p>\n\u003cp>As is the case with many startups, Jayalath started Athos to solve a personal problem.\u003c/p>\n\u003caside class=\"pullquote alignright\">“My old heart rate monitor is now sitting in the closet, gathering dust.'\"\u003cbr>\n\u003ccite>Eric Blue, Hexoskin user and the founder of Traqs\u003c/cite>\u003c/aside>\n\u003cp>He came up with the idea while studying electrical engineering in college. Jayalath, who frequently goes to the gym, said he couldn’t stop thinking about whether technology could replace a personal trainer.\u003c/p>\n\u003cp>“After we came up with the idea, people told us we were crazy and it wasn’t possible,” he said.\u003c/p>\n\u003cp>It took Jayalath and a fellow electrical engineer just five years to build a working prototype.\u003c/p>\n\u003cp>Against all expectations, Jayalath succeeded in developing apparel that can track muscle activity, heart rate recovery times and breathing rates. In the past, athletes would have needed to be hooked up to a machine in a performance lab to access this information.\u003c/p>\n\u003cp>Jayalath didn’t intend to build a product for sick people. But Athos has already received a great deal of interest from the medical community.\u003c/p>\n\u003cp>The company anticipates that its clothing will eventually be used in all kinds of clinical settings, such as hospitals and rehabilitation clinics. Smart clothing could benefit patients with a variety of medical conditions, including heart disease and obesity.\u003c/p>\n\u003cp>“Gradually over the next few years, these low-cost, consumer-focused, data-rich devices and apps will bring to bear vastly more data than physicians have in some circumstances,” said Pete Moran, a general partner at the venture capital firm \u003ca href=\"http://www.dcm.com/\">DCM\u003c/a>, which invested in Athos.\u003c/p>\n\u003cp>But selling to hospitals comes with strings attached.\u003c/p>\n\u003cp>“It would be far easier for a product like this to remain in the ‘wellness’ category,” said Morgan Reed, an executive director at \u003ca href=\"http://actonline.org/\">The App Association\u003c/a>, a Washington, D.C. nonprofit that works with patient advocates and app developers.\u003c/p>\n\u003cp>By saying they are helping improve fitness and well being, Reed said, these companies may hope to avoid regulatory oversight from government agencies like the U.S. Food and Drug Administration.\u003c/p>\n\u003cp>\u003cstrong>Smart Training to Smart Recovery\u003c/strong>\u003c/p>\n\u003cp>NBA All-Star Jermaine O’Neal \u003ca href=\"http://www.bizjournals.com/sanjose/news/2014/08/12/nbas-jermaine-oneal-joe-lacob-join-12-2m-funding.html?page=all\">recently endorsed and made a personal investment in\u003c/a> Athos because it helps him \"train smarter.\"\u003c/p>\n\u003cp>But how about helping surgical patients recover smarter?\u003c/p>\n\u003cp>“Fitness shirts could find a market in rehabilitation and could facilitate home exercises. That's just a thought,” said Dr. Molly Maloof, a general practitioner based in San Francisco, who has been closely following the wearable tech trend.\u003c/p>\n\u003caside class=\"pullquote alignleft\">\"There has been an explosion in patient-generated data, but much of it may not be useful to physicians in the short-term.\"\u003cbr>\n\u003ccite>Dr. Pat Basu,chief medical officer at Doctor On Demand\u003c/cite>\u003c/aside>\n\u003cp>Patients could wear biometric shirts and other apparel after surgeries, she said. Those who have recently undergone cardiac surgery, for instance, could be alerted if their heart rate is too high.\u003c/p>\n\u003cp>Smart clothing might also help people who are obese or overweight. Some doctors would consider recommending smart clothing to some of their patients, if it would inspire them to exercise regularly.\u003c/p>\n\u003cp>\"The fact is that the majority of Americans are in terrible shape,\" said Maloof. According to Maloof, fitness shirts could help get people on their feet, as long as the product proves to be more compelling than a barely-used gym membership.\u003c/p>\n\u003cp>Other physicians said they remain unconvinced that the data is precise. This mistrust doesn’t just apply to smart clothing, but the wearable-tech trend in general.\u003c/p>\n\u003cp>“There has been an explosion in patient-generated data, but much of it may not be useful to physicians in the short-term,” said Dr. Pat Basu, a former chief resident at Stanford University and current chief medical officer at \u003ca href=\"http://www.doctorondemand.com/\">Doctor On Demand\u003c/a>, an app that connects people to doctors.\u003c/p>\n\u003cp>“If a patient is showing me their blood pressure or heart rate they gathered from an app or device, I’ll always ask myself, ‘Is the fidelity of this information accurate or not?'”\u003c/p>\n\u003cp>Basu also said that wearable-tech makers should produce reports about each patient that doctors and nurses can skim. Many physicians are already inundated with the wealth of data that patients are generating from new wearable apps and devices, he said.\u003c/p>\n\u003cp>Moreover, some doctors fear that they will be liable if they miss something in the growing pile of patient data.\u003c/p>\n\u003cp>Privacy is another concern. The App Association’s executive director, Morgan Reed, has examined the privacy policies of companies like Athos.\u003c/p>\n\u003cp>He’s satisfied that patient’s sensitive health information is protected – for now.\u003c/p>\n\u003cp>But Reed expressed fears that the next crop of smart clothing companies might opt to offset the high cost of their products by selling people’s health data to pharmaceutical companies, insurance providers and even employers.\u003c/p>\n\u003cp>\u003ca href=\"http://www.fiercemobilehealthcare.com/story/senator-wants-ftc-rules-data-selling-wearable-device-companies/2014-08-11\">Fears are mounting among policymakers \u003c/a>that many of the most popular wearable tech companies are selling people’s personal health data, including step counts, hours of sleep and location.\u003c/p>\n\u003cp>\u003c/p>\u003c/div>","attributes":{"named":{},"numeric":[]}},{"type":"component","content":"","name":"ad","attributes":{"named":{"label":"floatright"},"numeric":["floatright"]}},{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003c/p>\n\u003cp>“Would consumers understand that they’re buying the version that is monetizing through data-sharing?” Reed said. “That’s the problem that everyone in the wearables industry is working on right now.”\u003c/p>\n\n\u003c/div>\u003c/p>","attributes":{"named":{},"numeric":[]}}],"link":"/futureofyou/1118/why-smart-clothing-is-the-next-frontier-for-wearable-health-tech","authors":["3252"],"programs":["futureofyou_54"],"categories":["futureofyou_1060"],"tags":["futureofyou_150","futureofyou_148","futureofyou_1225","futureofyou_152","futureofyou_138","futureofyou_61","futureofyou_151","futureofyou_80","futureofyou_149","futureofyou_25"],"featImg":"futureofyou_1120","label":"futureofyou_54"}},"programsReducer":{"possible":{"id":"possible","title":"Possible","info":"Possible is hosted by entrepreneur Reid Hoffman and writer Aria Finger. 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Each episode also includes a short fiction story generated by advanced AI GPT-4, serving as a thought-provoking springboard to speculate how humanity could leverage technology for good.","airtime":"SUN 2pm","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/Possible-Podcast-Tile-360x360-1.jpg","officialWebsiteLink":"https://www.possible.fm/","meta":{"site":"news","source":"Possible"},"link":"/radio/program/possible","subscribe":{"apple":"https://podcasts.apple.com/us/podcast/possible/id1677184070","spotify":"https://open.spotify.com/show/730YpdUSNlMyPQwNnyjp4k"}},"1a":{"id":"1a","title":"1A","info":"1A is home to the national conversation. 1A brings on great guests and frames the best debate in ways that make you think, share and engage.","airtime":"MON-THU 11pm-12am","imageSrc":"https://ww2.kqed.org/radio/wp-content/uploads/sites/50/2018/04/1a.jpg","officialWebsiteLink":"https://the1a.org/","meta":{"site":"news","source":"npr"},"link":"/radio/program/1a","subscribe":{"npr":"https://rpb3r.app.goo.gl/RBrW","apple":"https://itunes.apple.com/WebObjects/MZStore.woa/wa/viewPodcast?s=143441&mt=2&id=1188724250&at=11l79Y&ct=nprdirectory","tuneIn":"https://tunein.com/radio/1A-p947376/","rss":"https://feeds.npr.org/510316/podcast.xml"}},"all-things-considered":{"id":"all-things-considered","title":"All Things Considered","info":"Every weekday, \u003cem>All Things Considered\u003c/em> hosts Robert Siegel, Audie Cornish, Ari Shapiro, and Kelly McEvers present the program's trademark mix of news, interviews, commentaries, reviews, and offbeat features. 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But is this once sleepy suburb ready for them?","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/American-Suburb-Podcast-Tile-703x703-1.jpg","officialWebsiteLink":"/news/series/american-suburb-podcast","meta":{"site":"news","source":"kqed","order":"13"},"link":"/news/series/american-suburb-podcast/","subscribe":{"npr":"https://rpb3r.app.goo.gl/RBrW","apple":"https://itunes.apple.com/WebObjects/MZStore.woa/wa/viewPodcast?mt=2&id=1287748328","tuneIn":"https://tunein.com/radio/American-Suburb-p1086805/","rss":"https://ww2.kqed.org/news/series/american-suburb-podcast/feed/podcast","google":"https://podcasts.google.com/feed/aHR0cHM6Ly9mZWVkcy5tZWdhcGhvbmUuZm0vS1FJTkMzMDExODgxNjA5"}},"baycurious":{"id":"baycurious","title":"Bay Curious","tagline":"Exploring the Bay Area, one question at a time","info":"KQED’s new podcast, Bay Curious, gets to the bottom of the mysteries — both profound and peculiar — that give the Bay Area its unique identity. And we’ll do it with your help! You ask the questions. You decide what Bay Curious investigates. And you join us on the journey to find the answers.","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/Bay-Curious-Podcast-Tile-703x703-1.jpg","imageAlt":"\"KQED Bay Curious","officialWebsiteLink":"/news/series/baycurious","meta":{"site":"news","source":"kqed","order":"4"},"link":"/podcasts/baycurious","subscribe":{"apple":"https://podcasts.apple.com/us/podcast/bay-curious/id1172473406","npr":"https://www.npr.org/podcasts/500557090/bay-curious","rss":"https://ww2.kqed.org/news/category/bay-curious-podcast/feed/podcast","google":"https://podcasts.google.com/feed/aHR0cHM6Ly93dzIua3FlZC5vcmcvbmV3cy9jYXRlZ29yeS9iYXktY3VyaW91cy1wb2RjYXN0L2ZlZWQvcG9kY2FzdA","stitcher":"https://www.stitcher.com/podcast/kqed/bay-curious","spotify":"https://open.spotify.com/show/6O76IdmhixfijmhTZLIJ8k"}},"bbc-world-service":{"id":"bbc-world-service","title":"BBC World Service","info":"The day's top stories from BBC News compiled twice daily in the week, once at weekends.","airtime":"MON-FRI 9pm-10pm, TUE-FRI 1am-2am","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/BBC-World-Service-Podcast-Tile-360x360-1.jpg","officialWebsiteLink":"https://www.bbc.co.uk/sounds/play/live:bbc_world_service","meta":{"site":"news","source":"BBC World Service"},"link":"/radio/program/bbc-world-service","subscribe":{"apple":"https://itunes.apple.com/us/podcast/global-news-podcast/id135067274?mt=2","tuneIn":"https://tunein.com/radio/BBC-World-Service-p455581/","rss":"https://podcasts.files.bbci.co.uk/p02nq0gn.rss"}},"code-switch-life-kit":{"id":"code-switch-life-kit","title":"Code Switch / Life Kit","info":"\u003cem>Code Switch\u003c/em>, which listeners will hear in the first part of the hour, has fearless and much-needed conversations about race. Hosted by journalists of color, the show tackles the subject of race head-on, exploring how it impacts every part of society — from politics and pop culture to history, sports and more.\u003cbr />\u003cbr />\u003cem>Life Kit\u003c/em>, which will be in the second part of the hour, guides you through spaces and feelings no one prepares you for — from finances to mental health, from workplace microaggressions to imposter syndrome, from relationships to parenting. The show features experts with real world experience and shares their knowledge. Because everyone needs a little help being human.\u003cbr />\u003cbr />\u003ca href=\"https://www.npr.org/podcasts/510312/codeswitch\">\u003cem>Code Switch\u003c/em> offical site and podcast\u003c/a>\u003cbr />\u003ca href=\"https://www.npr.org/lifekit\">\u003cem>Life Kit\u003c/em> offical site and podcast\u003c/a>\u003cbr />","airtime":"SUN 9pm-10pm","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/Code-Switch-Life-Kit-Podcast-Tile-360x360-1.jpg","meta":{"site":"radio","source":"npr"},"link":"/radio/program/code-switch-life-kit","subscribe":{"apple":"https://podcasts.apple.com/podcast/1112190608?mt=2&at=11l79Y&ct=nprdirectory","google":"https://podcasts.google.com/feed/aHR0cHM6Ly93d3cubnByLm9yZy9yc3MvcG9kY2FzdC5waHA_aWQ9NTEwMzEy","spotify":"https://open.spotify.com/show/3bExJ9JQpkwNhoHvaIIuyV","rss":"https://feeds.npr.org/510312/podcast.xml"}},"commonwealth-club":{"id":"commonwealth-club","title":"Commonwealth Club of California Podcast","info":"The Commonwealth Club of California is the nation's oldest and largest public affairs forum. As a non-partisan forum, The Club brings to the public airwaves diverse viewpoints on important topics. The Club's weekly radio broadcast - the oldest in the U.S., dating back to 1924 - is carried across the nation on public radio stations and is now podcasting. Our website archive features audio of our recent programs, as well as selected speeches from our long and distinguished history. This podcast feed is usually updated twice a week and is always un-edited.","airtime":"THU 10pm, FRI 1am","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/Commonwealth-Club-Podcast-Tile-360x360-1.jpg","officialWebsiteLink":"https://www.commonwealthclub.org/podcasts","meta":{"site":"news","source":"Commonwealth Club of California"},"link":"/radio/program/commonwealth-club","subscribe":{"apple":"https://itunes.apple.com/us/podcast/commonwealth-club-of-california-podcast/id976334034?mt=2","google":"https://podcasts.google.com/feed/aHR0cDovL3d3dy5jb21tb253ZWFsdGhjbHViLm9yZy9hdWRpby9wb2RjYXN0L3dlZWtseS54bWw","tuneIn":"https://tunein.com/radio/Commonwealth-Club-of-California-p1060/"}},"considerthis":{"id":"considerthis","title":"Consider This","tagline":"Make sense of the day","info":"Make sense of the day. Every weekday afternoon, Consider This helps you consider the major stories of the day in less than 15 minutes, featuring the reporting and storytelling resources of NPR. Plus, KQED’s Bianca Taylor brings you the local KQED news you need to know.","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/Consider-This-Podcast-Tile-703x703-1.jpg","imageAlt":"Consider This from NPR and KQED","officialWebsiteLink":"/podcasts/considerthis","meta":{"site":"news","source":"kqed","order":"7"},"link":"/podcasts/considerthis","subscribe":{"apple":"https://podcasts.apple.com/podcast/id1503226625?mt=2&at=11l79Y&ct=nprdirectory","npr":"https://rpb3r.app.goo.gl/coronavirusdaily","google":"https://podcasts.google.com/feed/aHR0cHM6Ly9mZWVkcy5ucHIub3JnLzUxMDM1NS9wb2RjYXN0LnhtbA","spotify":"https://open.spotify.com/show/3Z6JdCS2d0eFEpXHKI6WqH"}},"forum":{"id":"forum","title":"Forum","tagline":"The conversation starts here","info":"KQED’s live call-in program discussing local, state, national and international issues, as well as in-depth interviews.","airtime":"MON-FRI 9am-11am, 10pm-11pm","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/Forum-Podcast-Tile-703x703-1.jpg","imageAlt":"KQED Forum with Mina Kim and Alexis Madrigal","officialWebsiteLink":"/forum","meta":{"site":"news","source":"kqed","order":"8"},"link":"/forum","subscribe":{"apple":"https://podcasts.apple.com/us/podcast/kqeds-forum/id73329719","google":"https://podcasts.google.com/feed/aHR0cHM6Ly9mZWVkcy5tZWdhcGhvbmUuZm0vS1FJTkM5NTU3MzgxNjMz","npr":"https://www.npr.org/podcasts/432307980/forum","stitcher":"https://www.stitcher.com/podcast/kqedfm-kqeds-forum-podcast","rss":"https://feeds.megaphone.fm/KQINC9557381633"}},"freakonomics-radio":{"id":"freakonomics-radio","title":"Freakonomics Radio","info":"Freakonomics Radio is a one-hour award-winning podcast and public-radio project hosted by Stephen Dubner, with co-author Steve Levitt as a regular guest. 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One of public radio's most popular programs, Fresh Air features intimate conversations with today's biggest luminaries.","airtime":"MON-FRI 7pm-8pm","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/Fresh-Air-Podcast-Tile-360x360-1.jpg","officialWebsiteLink":"https://www.npr.org/programs/fresh-air/","meta":{"site":"radio","source":"npr"},"link":"/radio/program/fresh-air","subscribe":{"npr":"https://rpb3r.app.goo.gl/4s8b","apple":"https://itunes.apple.com/WebObjects/MZStore.woa/wa/viewPodcast?s=143441&mt=2&id=214089682&at=11l79Y&ct=nprdirectory","tuneIn":"https://tunein.com/radio/Fresh-Air-p17/","rss":"https://feeds.npr.org/381444908/podcast.xml"}},"here-and-now":{"id":"here-and-now","title":"Here & Now","info":"A live production of NPR and WBUR Boston, in collaboration with stations across the country, Here & Now reflects the fluid world of news as it's happening in the middle of the day, with timely, in-depth news, interviews and conversation. Hosted by Robin Young, Jeremy Hobson and Tonya Mosley.","airtime":"MON-THU 11am-12pm","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/Here-And-Now-Podcast-Tile-360x360-1.jpg","officialWebsiteLink":"http://www.wbur.org/hereandnow","meta":{"site":"news","source":"npr"},"link":"/radio/program/here-and-now","subsdcribe":{"apple":"https://itunes.apple.com/WebObjects/MZStore.woa/wa/viewPodcast?mt=2&id=426698661","tuneIn":"https://tunein.com/radio/Here--Now-p211/","rss":"https://feeds.npr.org/510051/podcast.xml"}},"how-i-built-this":{"id":"how-i-built-this","title":"How I Built This with Guy Raz","info":"Guy Raz dives into the stories behind some of the world's best known companies. 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