In Future Fecal Transplants, "The Tool Won't Be Stool"
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(Open Biome)","credit":null,"description":"Massachusetts-based Open Biome sells frozen poop to doctors performing fecal transplants. 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Her science radio stories appear on KQED and NPR.\r\n\r\nEmail her at astanden@kqed.org","avatar":"https://secure.gravatar.com/avatar/3d021b72de685a788b0487b059d0a6a1?s=600&d=blank&r=g","twitter":null,"facebook":null,"instagram":null,"linkedin":null,"sites":[{"site":"news","roles":["subscriber"]},{"site":"futureofyou","roles":["subscriber"]},{"site":"stateofhealth","roles":["subscriber"]},{"site":"science","roles":["editor"]},{"site":"quest","roles":["subscriber"]}],"headData":{"title":"Amy Standen | KQED","description":null,"ogImgSrc":"https://secure.gravatar.com/avatar/3d021b72de685a788b0487b059d0a6a1?s=600&d=blank&r=g","twImgSrc":"https://secure.gravatar.com/avatar/3d021b72de685a788b0487b059d0a6a1?s=600&d=blank&r=g"},"isLoading":false,"link":"/author/amystanden"}},"breakingNewsReducer":{},"campaignFinanceReducer":{},"firebase":{"requesting":{},"requested":{},"timestamps":{},"data":{},"ordered":{},"auth":{"isLoaded":false,"isEmpty":true},"authError":null,"profile":{"isLoaded":false,"isEmpty":true},"listeners":{"byId":{},"allIds":[]},"isInitializing":false,"errors":[]},"navBarReducer":{"navBarId":"home","fullView":true,"showPlayer":false},"navMenuReducer":{"menus":[{"key":"menu1","items":[{"name":"News","link":"/","type":"title"},{"name":"Politics","link":"/politics"},{"name":"Science","link":"/science"},{"name":"Education","link":"/educationnews"},{"name":"Housing","link":"/housing"},{"name":"Immigration","link":"/immigration"},{"name":"Criminal Justice","link":"/criminaljustice"},{"name":"Silicon Valley","link":"/siliconvalley"},{"name":"Forum","link":"/forum"},{"name":"The California Report","link":"/californiareport"}]},{"key":"menu2","items":[{"name":"Arts & Culture","link":"/arts","type":"title"},{"name":"Critics’ Picks","link":"/thedolist"},{"name":"Cultural Commentary","link":"/artscommentary"},{"name":"Food & Drink","link":"/food"},{"name":"Bay Area Hip-Hop","link":"/bayareahiphop"},{"name":"Rebel Girls","link":"/rebelgirls"},{"name":"Arts Video","link":"/artsvideos"}]},{"key":"menu3","items":[{"name":"Podcasts","link":"/podcasts","type":"title"},{"name":"Bay Curious","link":"/podcasts/baycurious"},{"name":"Rightnowish","link":"/podcasts/rightnowish"},{"name":"The Bay","link":"/podcasts/thebay"},{"name":"On Our Watch","link":"/podcasts/onourwatch"},{"name":"Mindshift","link":"/podcasts/mindshift"},{"name":"Consider This","link":"/podcasts/considerthis"},{"name":"Political Breakdown","link":"/podcasts/politicalbreakdown"}]},{"key":"menu4","items":[{"name":"Live Radio","link":"/radio","type":"title"},{"name":"TV","link":"/tv","type":"title"},{"name":"Events","link":"/events","type":"title"},{"name":"For Educators","link":"/education","type":"title"},{"name":"Support KQED","link":"/support","type":"title"},{"name":"About","link":"/about","type":"title"},{"name":"Help Center","link":"https://kqed-helpcenter.kqed.org/s","type":"title"}]}]},"pagesReducer":{},"postsReducer":{"stream_live":{"type":"live","id":"stream_live","audioUrl":"https://streams.kqed.org/kqedradio","title":"Live Stream","excerpt":"Live Stream information currently unavailable.","link":"/radio","featImg":"","label":{"name":"KQED Live","link":"/"}},"stream_kqedNewscast":{"type":"posts","id":"stream_kqedNewscast","audioUrl":"https://www.kqed.org/.stream/anon/radio/RDnews/newscast.mp3?_=1","title":"KQED Newscast","featImg":"","label":{"name":"88.5 FM","link":"/"}},"futureofyou_4265":{"type":"posts","id":"futureofyou_4265","meta":{"index":"posts_1591205157","site":"futureofyou","id":"4265","score":null,"sort":[1434383370000]},"guestAuthors":[],"slug":"in-future-fecal-transplants-the-tool-wont-be-stool","title":"In Future Fecal Transplants, \"The Tool Won't Be Stool\"","publishDate":1434383370,"format":"audio","headTitle":"Future of You | KQED Future of You | KQED Science","labelTerm":{"term":54,"site":"futureofyou"},"content":"\u003cp>http://www.kqed.org/.stream/anon/radio/science/2015/06/Science_fecal_transplants.mp3\u003cbr>\nSeven years ago, a patient asked Neil Stollman, a gastroenterologist in Oakland, to do something so “absurd,” he says, he was tempted to turn her down immediately: to transplant feces from one person to another, using a colonoscopy tube.\u003c/p>\n\u003cp>“I said, 'No. What, are you crazy? I’m not putting poop in someone’s tush,'” recalls Stollman.\u003c/p>\n\u003cp>Still, Stollman had to admit it wasn’t an \u003cem>entirely\u003c/em> crazy idea.\u003c/p>\n\u003cp>The patient had C. diff, a disabling intestinal infection that kills about 15,000 people a year. C. diff is often picked up in hospitals or after heavy rounds of antibiotics.\u003c/p>\n\u003cfigure id=\"attachment_45978\" class=\"wp-caption alignleft\" style=\"max-width: 200px\">\u003ca href=\"http://ww2.kqed.org/science/wp-content/uploads/sites/35/2015/06/Neil-head-shot-new-better.jpg\">\u003cimg class=\" wp-image-45978\" src=\"http://ww2.kqed.org/science/wp-content/uploads/sites/35/2015/06/Neil-head-shot-new-better-800x1200.jpg\" alt=\"Neil Stollman, an Oakland-based gastroenterologist, was one of the first doctors to perform fecal transplants. (Neil Stollman)\" width=\"200\" height=\"300\">\u003c/a>\u003cfigcaption class=\"wp-caption-text\">Neil Stollman, an Oakland-based gastroenterologist, was one of the first doctors in the Bay Area to perform fecal transplants. (Neil Stollman)\u003c/figcaption>\u003c/figure>\n\u003cp>C. diff is caused by bad bacteria in the gut. So, Stollman says, once he \"got over the absolute ick-ness of it,\" it seemed logical that you might cure C. diff with good bacteria donated from a healthy person. The easiest place to find millions of live human gut bacteria? Poop.\u003c/p>\n\u003cp>[ad fullwidth]\u003c/p>\n\u003cp>The transplant worked. Stollman’s patient was cured.\u003c/p>\n\u003cp>Today, fecal transplants are widely accepted as an effective therapy for C. diff.\u003c/p>\n\u003cp>A handful of companies, including the Massachusetts-based \u003ca href=\"http://www.openbiome.org/\">Open Biome\u003c/a>, have sprung up to try and make the procedure more palatable, by providing pre-screened donor poop, or frozen poop pills that obviate the need for the tube. Meanwhile, about 70 clinical trials are in process to see what else fecal transplants might cure, but researchers say they haven’t seen the kind of slam dunk effect they do with C. diff.\u003c/p>\n\u003caside class=\"pullquote alignright\">“You have no idea what the life span of this microbe is going to be in that person's gut. It may be there for the rest of their life.”\u003ccite>Justin Sonnenburg, Stanford University\u003c/cite>\u003c/aside>\n\u003cp>And some researchers -- including Stollman -- say there’s got to be a better method, even for C. diff.\u003c/p>\n\u003cp>“This is a community of hundreds to thousands of species of microorganisms, so there’s just so much about it that we don’t understand,” says Justin Sonnenburg, a Stanford researcher and author of \u003cem>The Good Gut: Taking Control of Your Weight, Your Mood, and your Long Term Health\u003c/em>.\u003c/p>\n\u003cp>Sonnenburg calls fecal transplants a kitchen-sink approach. Rather than pinpointing specific bacteria in the patient’s gut, the transplant largely replaces it with trillions of live bacteria, many of whose functions are still unknown. They could make the patient sicker.\u003c/p>\n\u003cp>And remember, they’re alive. The whole idea of dosage kind of flies out the window.\u003c/p>\n\u003cp>“You have no idea what the life span of this microbe is going to be in that person's gut,” says Sonnenburg. “It may be there for the rest of their life.”\u003c/p>\n\u003cfigure id=\"attachment_45981\" class=\"wp-caption alignleft\" style=\"max-width: 395px\">\u003ca href=\"http://ww2.kqed.org/science/wp-content/uploads/sites/35/2015/06/IMG_0089.jpg\">\u003cimg class=\" wp-image-45981\" src=\"http://ww2.kqed.org/science/wp-content/uploads/sites/35/2015/06/IMG_0089-800x600.jpg\" alt=\"Peter DiLaura is CEO of Second Genome in South Francisco.\" width=\"395\" height=\"296\">\u003c/a>\u003cfigcaption class=\"wp-caption-text\">Peter DiLaura is CEO of Second Genome in South Francisco.\u003c/figcaption>\u003c/figure>\n\u003cp>In South San Francisco, a company called \u003ca href=\"http://www.secondgenome.com/\">Second Genome\u003c/a> is looking for a way around that problem.\u003c/p>\n\u003cp>CEO Peter DiLaura opens a freezer full of glass vials. They’re samples of poop, naturally, but also samples from other microbial communities, such as the bacteria and other organisms that live on our skin.\u003c/p>\n\u003cp>Second Genome collects samples from hundreds of people with specific diseases, like for example, inflammatory bowel disease, or IBD.\u003c/p>\n\u003cp>Using $100,000 Illumina gene sequencers, researchers scan the patients' microbiota to look for commonalities. Perhaps some bacteria are more prevalent, or conspicuously absent, in people who have the disease.\u003c/p>\n\u003cp>The next question, says DiLaura, is what those specific bacteria are doing.\u003c/p>\n\u003cp>“What are they secreting? And how do the things that they secrete affect the human biology of that disease?”\u003c/p>\n\u003cfigure id=\"attachment_45983\" class=\"wp-caption alignright\" style=\"max-width: 479px\">\u003ca href=\"http://ww2.kqed.org/science/wp-content/uploads/sites/35/2015/06/IMG_0071.jpg\">\u003cimg class=\" wp-image-45983\" src=\"http://ww2.kqed.org/science/wp-content/uploads/sites/35/2015/06/IMG_0071.jpg\" alt=\"At Second Genome, hundreds of stool samples from patients with IBD and other diseases are stored in freezers. (Amy Standen/KQED)\" width=\"479\" height=\"359\">\u003c/a>\u003cfigcaption class=\"wp-caption-text\">At Second Genome, hundreds of stool samples from patients with IBD and other diseases are stored in freezers. (Amy Standen/KQED)\u003c/figcaption>\u003c/figure>\n\u003cp>Maybe there are chemicals out there that could target -- actually zero in on -- those specific bacteria.\u003c/p>\n\u003cp>The goal is a drug that blocks the damaging effects of the microbiome in inflammatory bowel disease. Second Genome's first drug is currently in Phase 1 clinical trials, which are designed to show whether a product is safe. Subsequent phases, in a process that could take several years or longer, test for efficacy.\u003c/p>\n\u003cp>Unlike antibiotics, which kill bacteria largely indiscriminately, these drugs would feed certain bacteria and starve others. And because there’s no actual, live bacteria involved, there’s less of a concern about dosage.\u003c/p>\n\u003cp>If it works, says Dr. Neil Stollman, in Oakland, one day in the not-so-distant future, “the tool won’t be stool.”\u003c/p>\n\u003cp>That is, live poop might eventually be replaced with something a lot more like a pill. Inert. Odorless. Something the FDA could regulate and doctors could prescribe.\u003c/p>\n\u003cp>\u003c/p>\n\u003cp>Of course that’d put Stollman out of the fecal transplant business. He says that is fine with him.\u003c/p>\n\n","blocks":[],"excerpt":"Researchers are seeking a treatment a bit less yucky, and more targeted, than the live bacteria in poop.","status":"publish","parent":0,"modified":1477281685,"stats":{"hasAudio":true,"hasVideo":false,"hasChartOrMap":false,"iframeSrcs":[],"hasGoogleForm":false,"hasGallery":false,"hasHearkenModule":false,"hasPolis":false,"paragraphCount":26,"wordCount":838},"headData":{"title":"In Future Fecal Transplants, \"The Tool Won't Be Stool\" | KQED","description":"Researchers are seeking a treatment a bit less yucky, and more targeted, than the live bacteria in poop.","ogTitle":"","ogDescription":"","ogImgId":"","twTitle":"","twDescription":"","twImgId":"","schema":{"@context":"http://schema.org","@type":"Article","headline":"In Future Fecal Transplants, \"The Tool Won't Be Stool\"","datePublished":"2015-06-15T15:49:30.000Z","dateModified":"2016-10-24T04:01:25.000Z","image":"https://cdn.kqed.org/wp-content/uploads/2020/02/KQED-OG-Image@1x.png"}},"disqusIdentifier":"4265 http://ww2.kqed.org/futureofyou/?p=4265","disqusUrl":"https://ww2.kqed.org/futureofyou/2015/06/15/in-future-fecal-transplants-the-tool-wont-be-stool/","disqusTitle":"In Future Fecal Transplants, \"The Tool Won't Be Stool\"","path":"/futureofyou/4265/in-future-fecal-transplants-the-tool-wont-be-stool","audioUrl":"http://www.kqed.org/.stream/anon/radio/science/2015/06/Science_fecal_transplants.mp3","audioDuration":null,"audioTrackLength":null,"parsedContent":[{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003cp>http://www.kqed.org/.stream/anon/radio/science/2015/06/Science_fecal_transplants.mp3\u003cbr>\nSeven years ago, a patient asked Neil Stollman, a gastroenterologist in Oakland, to do something so “absurd,” he says, he was tempted to turn her down immediately: to transplant feces from one person to another, using a colonoscopy tube.\u003c/p>\n\u003cp>“I said, 'No. What, are you crazy? I’m not putting poop in someone’s tush,'” recalls Stollman.\u003c/p>\n\u003cp>Still, Stollman had to admit it wasn’t an \u003cem>entirely\u003c/em> crazy idea.\u003c/p>\n\u003cp>The patient had C. diff, a disabling intestinal infection that kills about 15,000 people a year. C. diff is often picked up in hospitals or after heavy rounds of antibiotics.\u003c/p>\n\u003cfigure id=\"attachment_45978\" class=\"wp-caption alignleft\" style=\"max-width: 200px\">\u003ca href=\"http://ww2.kqed.org/science/wp-content/uploads/sites/35/2015/06/Neil-head-shot-new-better.jpg\">\u003cimg class=\" wp-image-45978\" src=\"http://ww2.kqed.org/science/wp-content/uploads/sites/35/2015/06/Neil-head-shot-new-better-800x1200.jpg\" alt=\"Neil Stollman, an Oakland-based gastroenterologist, was one of the first doctors to perform fecal transplants. (Neil Stollman)\" width=\"200\" height=\"300\">\u003c/a>\u003cfigcaption class=\"wp-caption-text\">Neil Stollman, an Oakland-based gastroenterologist, was one of the first doctors in the Bay Area to perform fecal transplants. (Neil Stollman)\u003c/figcaption>\u003c/figure>\n\u003cp>C. diff is caused by bad bacteria in the gut. So, Stollman says, once he \"got over the absolute ick-ness of it,\" it seemed logical that you might cure C. diff with good bacteria donated from a healthy person. The easiest place to find millions of live human gut bacteria? Poop.\u003c/p>\n\u003cp>\u003c/p>\u003c/div>","attributes":{"named":{},"numeric":[]}},{"type":"component","content":"","name":"ad","attributes":{"named":{"label":"fullwidth"},"numeric":["fullwidth"]}},{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003c/p>\n\u003cp>The transplant worked. Stollman’s patient was cured.\u003c/p>\n\u003cp>Today, fecal transplants are widely accepted as an effective therapy for C. diff.\u003c/p>\n\u003cp>A handful of companies, including the Massachusetts-based \u003ca href=\"http://www.openbiome.org/\">Open Biome\u003c/a>, have sprung up to try and make the procedure more palatable, by providing pre-screened donor poop, or frozen poop pills that obviate the need for the tube. Meanwhile, about 70 clinical trials are in process to see what else fecal transplants might cure, but researchers say they haven’t seen the kind of slam dunk effect they do with C. diff.\u003c/p>\n\u003caside class=\"pullquote alignright\">“You have no idea what the life span of this microbe is going to be in that person's gut. It may be there for the rest of their life.”\u003ccite>Justin Sonnenburg, Stanford University\u003c/cite>\u003c/aside>\n\u003cp>And some researchers -- including Stollman -- say there’s got to be a better method, even for C. diff.\u003c/p>\n\u003cp>“This is a community of hundreds to thousands of species of microorganisms, so there’s just so much about it that we don’t understand,” says Justin Sonnenburg, a Stanford researcher and author of \u003cem>The Good Gut: Taking Control of Your Weight, Your Mood, and your Long Term Health\u003c/em>.\u003c/p>\n\u003cp>Sonnenburg calls fecal transplants a kitchen-sink approach. Rather than pinpointing specific bacteria in the patient’s gut, the transplant largely replaces it with trillions of live bacteria, many of whose functions are still unknown. They could make the patient sicker.\u003c/p>\n\u003cp>And remember, they’re alive. The whole idea of dosage kind of flies out the window.\u003c/p>\n\u003cp>“You have no idea what the life span of this microbe is going to be in that person's gut,” says Sonnenburg. “It may be there for the rest of their life.”\u003c/p>\n\u003cfigure id=\"attachment_45981\" class=\"wp-caption alignleft\" style=\"max-width: 395px\">\u003ca href=\"http://ww2.kqed.org/science/wp-content/uploads/sites/35/2015/06/IMG_0089.jpg\">\u003cimg class=\" wp-image-45981\" src=\"http://ww2.kqed.org/science/wp-content/uploads/sites/35/2015/06/IMG_0089-800x600.jpg\" alt=\"Peter DiLaura is CEO of Second Genome in South Francisco.\" width=\"395\" height=\"296\">\u003c/a>\u003cfigcaption class=\"wp-caption-text\">Peter DiLaura is CEO of Second Genome in South Francisco.\u003c/figcaption>\u003c/figure>\n\u003cp>In South San Francisco, a company called \u003ca href=\"http://www.secondgenome.com/\">Second Genome\u003c/a> is looking for a way around that problem.\u003c/p>\n\u003cp>CEO Peter DiLaura opens a freezer full of glass vials. They’re samples of poop, naturally, but also samples from other microbial communities, such as the bacteria and other organisms that live on our skin.\u003c/p>\n\u003cp>Second Genome collects samples from hundreds of people with specific diseases, like for example, inflammatory bowel disease, or IBD.\u003c/p>\n\u003cp>Using $100,000 Illumina gene sequencers, researchers scan the patients' microbiota to look for commonalities. Perhaps some bacteria are more prevalent, or conspicuously absent, in people who have the disease.\u003c/p>\n\u003cp>The next question, says DiLaura, is what those specific bacteria are doing.\u003c/p>\n\u003cp>“What are they secreting? And how do the things that they secrete affect the human biology of that disease?”\u003c/p>\n\u003cfigure id=\"attachment_45983\" class=\"wp-caption alignright\" style=\"max-width: 479px\">\u003ca href=\"http://ww2.kqed.org/science/wp-content/uploads/sites/35/2015/06/IMG_0071.jpg\">\u003cimg class=\" wp-image-45983\" src=\"http://ww2.kqed.org/science/wp-content/uploads/sites/35/2015/06/IMG_0071.jpg\" alt=\"At Second Genome, hundreds of stool samples from patients with IBD and other diseases are stored in freezers. (Amy Standen/KQED)\" width=\"479\" height=\"359\">\u003c/a>\u003cfigcaption class=\"wp-caption-text\">At Second Genome, hundreds of stool samples from patients with IBD and other diseases are stored in freezers. (Amy Standen/KQED)\u003c/figcaption>\u003c/figure>\n\u003cp>Maybe there are chemicals out there that could target -- actually zero in on -- those specific bacteria.\u003c/p>\n\u003cp>The goal is a drug that blocks the damaging effects of the microbiome in inflammatory bowel disease. Second Genome's first drug is currently in Phase 1 clinical trials, which are designed to show whether a product is safe. Subsequent phases, in a process that could take several years or longer, test for efficacy.\u003c/p>\n\u003cp>Unlike antibiotics, which kill bacteria largely indiscriminately, these drugs would feed certain bacteria and starve others. And because there’s no actual, live bacteria involved, there’s less of a concern about dosage.\u003c/p>\n\u003cp>If it works, says Dr. Neil Stollman, in Oakland, one day in the not-so-distant future, “the tool won’t be stool.”\u003c/p>\n\u003cp>That is, live poop might eventually be replaced with something a lot more like a pill. Inert. Odorless. Something the FDA could regulate and doctors could prescribe.\u003c/p>\n\u003cp>\u003c/p>\n\u003cp>Of course that’d put Stollman out of the fecal transplant business. He says that is fine with him.\u003c/p>\n\n\u003c/div>\u003c/p>","attributes":{"named":{},"numeric":[]}}],"link":"/futureofyou/4265/in-future-fecal-transplants-the-tool-wont-be-stool","authors":["210"],"programs":["futureofyou_54"],"categories":["futureofyou_1062","futureofyou_1064"],"tags":["futureofyou_440","futureofyou_439","futureofyou_80"],"featImg":"futureofyou_4268","label":"futureofyou_54"}},"programsReducer":{"possible":{"id":"possible","title":"Possible","info":"Possible is hosted by entrepreneur Reid Hoffman and writer Aria Finger. Together in Possible, Hoffman and Finger lead enlightening discussions about building a brighter collective future. The show features interviews with visionary guests like Trevor Noah, Sam Altman and Janette Sadik-Khan. Possible paints an optimistic portrait of the world we can create through science, policy, business, art and our shared humanity. It asks: What if everything goes right for once? How can we get there? 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Michel Martin hosts on the weekends.","airtime":"MON-FRI 1pm-2pm, 4:30pm-6:30pm\u003cbr />SAT-SUN 5pm-6pm","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/All-Things-Considered-Podcast-Tile-360x360-1.jpg","officialWebsiteLink":"https://www.npr.org/programs/all-things-considered/","meta":{"site":"news","source":"npr"},"link":"/radio/program/all-things-considered"},"american-suburb-podcast":{"id":"american-suburb-podcast","title":"American Suburb: The Podcast","tagline":"The flip side of gentrification, told through one town","info":"Gentrification is changing cities across America, forcing people from neighborhoods they have long called home. Call them the displaced. Now those priced out of the Bay Area are looking for a better life in an unlikely place. American Suburb follows this migration to one California town along the Delta, 45 miles from San Francisco. 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You ask the questions. You decide what Bay Curious investigates. And you join us on the journey to find the answers.","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/Bay-Curious-Podcast-Tile-703x703-1.jpg","imageAlt":"\"KQED Bay Curious","officialWebsiteLink":"/news/series/baycurious","meta":{"site":"news","source":"kqed","order":"4"},"link":"/podcasts/baycurious","subscribe":{"apple":"https://podcasts.apple.com/us/podcast/bay-curious/id1172473406","npr":"https://www.npr.org/podcasts/500557090/bay-curious","rss":"https://ww2.kqed.org/news/category/bay-curious-podcast/feed/podcast","google":"https://podcasts.google.com/feed/aHR0cHM6Ly93dzIua3FlZC5vcmcvbmV3cy9jYXRlZ29yeS9iYXktY3VyaW91cy1wb2RjYXN0L2ZlZWQvcG9kY2FzdA","stitcher":"https://www.stitcher.com/podcast/kqed/bay-curious","spotify":"https://open.spotify.com/show/6O76IdmhixfijmhTZLIJ8k"}},"bbc-world-service":{"id":"bbc-world-service","title":"BBC World Service","info":"The day's top stories from BBC News compiled twice daily in the week, once at weekends.","airtime":"MON-FRI 9pm-10pm, TUE-FRI 1am-2am","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/BBC-World-Service-Podcast-Tile-360x360-1.jpg","officialWebsiteLink":"https://www.bbc.co.uk/sounds/play/live:bbc_world_service","meta":{"site":"news","source":"BBC World Service"},"link":"/radio/program/bbc-world-service","subscribe":{"apple":"https://itunes.apple.com/us/podcast/global-news-podcast/id135067274?mt=2","tuneIn":"https://tunein.com/radio/BBC-World-Service-p455581/","rss":"https://podcasts.files.bbci.co.uk/p02nq0gn.rss"}},"code-switch-life-kit":{"id":"code-switch-life-kit","title":"Code Switch / Life Kit","info":"\u003cem>Code Switch\u003c/em>, which listeners will hear in the first part of the hour, has fearless and much-needed conversations about race. Hosted by journalists of color, the show tackles the subject of race head-on, exploring how it impacts every part of society — from politics and pop culture to history, sports and more.\u003cbr />\u003cbr />\u003cem>Life Kit\u003c/em>, which will be in the second part of the hour, guides you through spaces and feelings no one prepares you for — from finances to mental health, from workplace microaggressions to imposter syndrome, from relationships to parenting. The show features experts with real world experience and shares their knowledge. Because everyone needs a little help being human.\u003cbr />\u003cbr />\u003ca href=\"https://www.npr.org/podcasts/510312/codeswitch\">\u003cem>Code Switch\u003c/em> offical site and podcast\u003c/a>\u003cbr />\u003ca href=\"https://www.npr.org/lifekit\">\u003cem>Life Kit\u003c/em> offical site and podcast\u003c/a>\u003cbr />","airtime":"SUN 9pm-10pm","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/Code-Switch-Life-Kit-Podcast-Tile-360x360-1.jpg","meta":{"site":"radio","source":"npr"},"link":"/radio/program/code-switch-life-kit","subscribe":{"apple":"https://podcasts.apple.com/podcast/1112190608?mt=2&at=11l79Y&ct=nprdirectory","google":"https://podcasts.google.com/feed/aHR0cHM6Ly93d3cubnByLm9yZy9yc3MvcG9kY2FzdC5waHA_aWQ9NTEwMzEy","spotify":"https://open.spotify.com/show/3bExJ9JQpkwNhoHvaIIuyV","rss":"https://feeds.npr.org/510312/podcast.xml"}},"commonwealth-club":{"id":"commonwealth-club","title":"Commonwealth Club of California Podcast","info":"The Commonwealth Club of California is the nation's oldest and largest public affairs forum. As a non-partisan forum, The Club brings to the public airwaves diverse viewpoints on important topics. The Club's weekly radio broadcast - the oldest in the U.S., dating back to 1924 - is carried across the nation on public radio stations and is now podcasting. Our website archive features audio of our recent programs, as well as selected speeches from our long and distinguished history. This podcast feed is usually updated twice a week and is always un-edited.","airtime":"THU 10pm, FRI 1am","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/Commonwealth-Club-Podcast-Tile-360x360-1.jpg","officialWebsiteLink":"https://www.commonwealthclub.org/podcasts","meta":{"site":"news","source":"Commonwealth Club of California"},"link":"/radio/program/commonwealth-club","subscribe":{"apple":"https://itunes.apple.com/us/podcast/commonwealth-club-of-california-podcast/id976334034?mt=2","google":"https://podcasts.google.com/feed/aHR0cDovL3d3dy5jb21tb253ZWFsdGhjbHViLm9yZy9hdWRpby9wb2RjYXN0L3dlZWtseS54bWw","tuneIn":"https://tunein.com/radio/Commonwealth-Club-of-California-p1060/"}},"considerthis":{"id":"considerthis","title":"Consider This","tagline":"Make sense of the day","info":"Make sense of the day. Every weekday afternoon, Consider This helps you consider the major stories of the day in less than 15 minutes, featuring the reporting and storytelling resources of NPR. Plus, KQED’s Bianca Taylor brings you the local KQED news you need to know.","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/Consider-This-Podcast-Tile-703x703-1.jpg","imageAlt":"Consider This from NPR and KQED","officialWebsiteLink":"/podcasts/considerthis","meta":{"site":"news","source":"kqed","order":"7"},"link":"/podcasts/considerthis","subscribe":{"apple":"https://podcasts.apple.com/podcast/id1503226625?mt=2&at=11l79Y&ct=nprdirectory","npr":"https://rpb3r.app.goo.gl/coronavirusdaily","google":"https://podcasts.google.com/feed/aHR0cHM6Ly9mZWVkcy5ucHIub3JnLzUxMDM1NS9wb2RjYXN0LnhtbA","spotify":"https://open.spotify.com/show/3Z6JdCS2d0eFEpXHKI6WqH"}},"forum":{"id":"forum","title":"Forum","tagline":"The conversation starts here","info":"KQED’s live call-in program discussing local, state, national and international issues, as well as in-depth interviews.","airtime":"MON-FRI 9am-11am, 10pm-11pm","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/Forum-Podcast-Tile-703x703-1.jpg","imageAlt":"KQED Forum with Mina Kim and Alexis Madrigal","officialWebsiteLink":"/forum","meta":{"site":"news","source":"kqed","order":"8"},"link":"/forum","subscribe":{"apple":"https://podcasts.apple.com/us/podcast/kqeds-forum/id73329719","google":"https://podcasts.google.com/feed/aHR0cHM6Ly9mZWVkcy5tZWdhcGhvbmUuZm0vS1FJTkM5NTU3MzgxNjMz","npr":"https://www.npr.org/podcasts/432307980/forum","stitcher":"https://www.stitcher.com/podcast/kqedfm-kqeds-forum-podcast","rss":"https://feeds.megaphone.fm/KQINC9557381633"}},"freakonomics-radio":{"id":"freakonomics-radio","title":"Freakonomics Radio","info":"Freakonomics Radio is a one-hour award-winning podcast and public-radio project hosted by Stephen Dubner, with co-author Steve Levitt as a regular guest. 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Hosted by Robin Young, Jeremy Hobson and Tonya Mosley.","airtime":"MON-THU 11am-12pm","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/Here-And-Now-Podcast-Tile-360x360-1.jpg","officialWebsiteLink":"http://www.wbur.org/hereandnow","meta":{"site":"news","source":"npr"},"link":"/radio/program/here-and-now","subsdcribe":{"apple":"https://itunes.apple.com/WebObjects/MZStore.woa/wa/viewPodcast?mt=2&id=426698661","tuneIn":"https://tunein.com/radio/Here--Now-p211/","rss":"https://feeds.npr.org/510051/podcast.xml"}},"how-i-built-this":{"id":"how-i-built-this","title":"How I Built This with Guy Raz","info":"Guy Raz dives into the stories behind some of the world's best known companies. 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Updated Monday through Friday at about 3:30 p.m. PT.","airtime":"MON-FRI 4pm-4:30pm, MON-WED 6:30pm-7pm","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/Marketplace-Podcast-Tile-360x360-1.jpg","officialWebsiteLink":"https://www.marketplace.org/","meta":{"site":"news","source":"American Public Media"},"link":"/radio/program/marketplace","subscribe":{"apple":"https://itunes.apple.com/WebObjects/MZStore.woa/wa/viewPodcast?s=143441&mt=2&id=201853034&at=11l79Y&ct=nprdirectory","tuneIn":"https://tunein.com/radio/APM-Marketplace-p88/","rss":"https://feeds.publicradio.org/public_feeds/marketplace-pm/rss/rss"}},"mindshift":{"id":"mindshift","title":"MindShift","tagline":"A podcast about the future of learning and how we raise our kids","info":"The MindShift podcast explores the innovations in education that are shaping how kids learn. Hosts Ki Sung and Katrina Schwartz introduce listeners to educators, researchers, parents and students who are developing effective ways to improve how kids learn. We cover topics like how fed-up administrators are developing surprising tactics to deal with classroom disruptions; how listening to podcasts are helping kids develop reading skills; the consequences of overparenting; and why interdisciplinary learning can engage students on all ends of the traditional achievement spectrum. This podcast is part of the MindShift education site, a division of KQED News. KQED is an NPR/PBS member station based in San Francisco. You can also visit the MindShift website for episodes and supplemental blog posts or tweet us \u003ca href=\"https://twitter.com/MindShiftKQED\">@MindShiftKQED\u003c/a> or visit us at \u003ca href=\"/mindshift\">MindShift.KQED.org\u003c/a>","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/Mindshift-Podcast-Tile-703x703-1.jpg","imageAlt":"KQED MindShift: How We Will Learn","officialWebsiteLink":"/mindshift/","meta":{"site":"news","source":"kqed","order":"2"},"link":"/podcasts/mindshift","subscribe":{"apple":"https://podcasts.apple.com/us/podcast/mindshift-podcast/id1078765985","google":"https://podcasts.google.com/feed/aHR0cHM6Ly9mZWVkcy5tZWdhcGhvbmUuZm0vS1FJTkM1NzY0NjAwNDI5","npr":"https://www.npr.org/podcasts/464615685/mind-shift-podcast","stitcher":"https://www.stitcher.com/podcast/kqed/stories-teachers-share","spotify":"https://open.spotify.com/show/0MxSpNYZKNprFLCl7eEtyx"}},"morning-edition":{"id":"morning-edition","title":"Morning Edition","info":"\u003cem>Morning Edition\u003c/em> takes listeners around the country and the world with multi-faceted stories and commentaries every weekday. 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