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Follow her on twitter @LFarrarAtWork","avatar":"https://secure.gravatar.com/avatar/580c4ece9fa0756ef42202cdcf4146d1?s=600&d=blank&r=g","twitter":null,"facebook":null,"instagram":null,"linkedin":null,"sites":[{"site":"lowdown","roles":["editor"]},{"site":"science","roles":["editor"]},{"site":"education","roles":["administrator"]},{"site":"quest","roles":["administrator"]}],"headData":{"title":"Lauren Farrar | KQED","description":null,"ogImgSrc":"https://secure.gravatar.com/avatar/580c4ece9fa0756ef42202cdcf4146d1?s=600&d=blank&r=g","twImgSrc":"https://secure.gravatar.com/avatar/580c4ece9fa0756ef42202cdcf4146d1?s=600&d=blank&r=g"},"isLoading":false,"link":"/author/lfarrar"},"darya-pino":{"type":"authors","id":"10218","meta":{"index":"authors_1591205172","id":"10218","found":true},"name":"Darya Pino","firstName":"Darya","lastName":"Pino","slug":"darya-pino","email":"darya@summertomato.com","display_author_email":false,"staff_mastheads":[],"title":null,"bio":"Darya Pino is a Ph.D trained scientist, San Francisco foodie, food and health writer and advocate of local, seasonal foods. 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Follow her on Twitter @summertomato.","avatar":"https://secure.gravatar.com/avatar/b5303fe7938a19bb9d4baa7837fb8390?s=600&d=blank&r=g","twitter":null,"facebook":null,"instagram":null,"linkedin":null,"sites":[{"site":"quest","roles":["subscriber"]}],"headData":{"title":"Darya Pino | KQED","description":null,"ogImgSrc":"https://secure.gravatar.com/avatar/b5303fe7938a19bb9d4baa7837fb8390?s=600&d=blank&r=g","twImgSrc":"https://secure.gravatar.com/avatar/b5303fe7938a19bb9d4baa7837fb8390?s=600&d=blank&r=g"},"isLoading":false,"link":"/author/darya-pino"}},"breakingNewsReducer":{},"campaignFinanceReducer":{},"firebase":{"requesting":{},"requested":{},"timestamps":{},"data":{},"ordered":{},"auth":{"isLoaded":false,"isEmpty":true},"authError":null,"profile":{"isLoaded":false,"isEmpty":true},"listeners":{"byId":{},"allIds":[]},"isInitializing":false,"errors":[]},"navBarReducer":{"navBarId":"home","fullView":true,"showPlayer":false},"navMenuReducer":{"menus":[{"key":"menu1","items":[{"name":"News","link":"/","type":"title"},{"name":"Politics","link":"/politics"},{"name":"Science","link":"/science"},{"name":"Education","link":"/educationnews"},{"name":"Housing","link":"/housing"},{"name":"Immigration","link":"/immigration"},{"name":"Criminal Justice","link":"/criminaljustice"},{"name":"Silicon Valley","link":"/siliconvalley"},{"name":"Forum","link":"/forum"},{"name":"The California Report","link":"/californiareport"}]},{"key":"menu2","items":[{"name":"Arts & Culture","link":"/arts","type":"title"},{"name":"Critics’ Picks","link":"/thedolist"},{"name":"Cultural Commentary","link":"/artscommentary"},{"name":"Food & Drink","link":"/food"},{"name":"Bay Area Hip-Hop","link":"/bayareahiphop"},{"name":"Rebel Girls","link":"/rebelgirls"},{"name":"Arts Video","link":"/artsvideos"}]},{"key":"menu3","items":[{"name":"Podcasts","link":"/podcasts","type":"title"},{"name":"Bay Curious","link":"/podcasts/baycurious"},{"name":"Rightnowish","link":"/podcasts/rightnowish"},{"name":"The Bay","link":"/podcasts/thebay"},{"name":"On Our Watch","link":"/podcasts/onourwatch"},{"name":"Mindshift","link":"/podcasts/mindshift"},{"name":"Consider This","link":"/podcasts/considerthis"},{"name":"Political Breakdown","link":"/podcasts/politicalbreakdown"}]},{"key":"menu4","items":[{"name":"Live Radio","link":"/radio","type":"title"},{"name":"TV","link":"/tv","type":"title"},{"name":"Events","link":"/events","type":"title"},{"name":"For Educators","link":"/education","type":"title"},{"name":"Support KQED","link":"/support","type":"title"},{"name":"About","link":"/about","type":"title"},{"name":"Help Center","link":"https://kqed-helpcenter.kqed.org/s","type":"title"}]}]},"pagesReducer":{},"postsReducer":{"stream_live":{"type":"live","id":"stream_live","audioUrl":"https://streams.kqed.org/kqedradio","title":"Live Stream","excerpt":"Live Stream information currently unavailable.","link":"/radio","featImg":"","label":{"name":"KQED Live","link":"/"}},"stream_kqedNewscast":{"type":"posts","id":"stream_kqedNewscast","audioUrl":"https://www.kqed.org/.stream/anon/radio/RDnews/newscast.mp3?_=1","title":"KQED Newscast","featImg":"","label":{"name":"88.5 FM","link":"/"}},"quest_74092":{"type":"posts","id":"quest_74092","meta":{"index":"posts_1591205157","site":"quest","id":"74092","score":null,"sort":[1431625782000]},"guestAuthors":[],"slug":"career-spotlight-developmental-and-stem-cell-biology-graduate-student","title":"Career Spotlight: Developmental and Stem Cell Biology Graduate Student","publishDate":1431625782,"format":"video","headTitle":"Career Spotlight | QUEST | KQED Science","labelTerm":{},"content":"\u003cp>\u003cem>Trouble viewing the video? Stream or download it on \u003ca href=\"http://www.pbslearningmedia.org/resource/c7e42f18-46b1-4cb8-8588-1c628a3e5b18/developmental-stem-cell-biology-graduate-student/\"> PBS LearningMedia\u003c/a>.\u003c/em>\u003cbr>\n \u003cbr>\nElijah Martin is a second-year graduate student in the \u003ca href=\"https://dscb.ucsf.edu/\">Developmental and Stem Cell Biology \u003c/a>program at University of California, San Francisco. He works in the laboratory of \u003ca href=\"http://gladstoneinstitutes.org/u/dsrivastava/SrivastavaLab.htm\">Dr. Deepak Srivastava \u003c/a>at the Gladstone Institutes. Martin studies how the heart forms to try to understand the causes of heart disease in order to develop therapies. In the lab, he grows heart cells in petri dishes, which involves mixing together different chemicals and nutrients to get the cells to grow and develop into a heart. He uses microscopes to track the growth of the cells. Since he was a young child, Martin has wanted to study the heart and he says attending graduate school will help turn his dream into a career.\u003c/p>\n\u003cp>This video is featured in our \u003cb>\u003ca href=\"http://foldscope.woop.ie/\" target=\"_blank\">Engineering Is: Diagnosing Diseases with Origami Microscopes\u003c/a>\u003c/b>e-book. You can find our other e-books at \u003ca href=\"http://blogs.kqed.org/education/e-books/\">kqed.org/ebooks\u003c/a>.\u003c/p>\n\u003cp>[ad fullwidth]\u003c/p>\u003cp>\u003c/p>\n","blocks":[],"excerpt":"Elijah Martin is a graduate student in Dr. Deepak Srivastava's Lab at Gladstone Institutes where he studies how the heart develops. ","status":"publish","parent":0,"modified":1450483280,"stats":{"hasAudio":false,"hasVideo":false,"hasChartOrMap":false,"iframeSrcs":[],"hasGoogleForm":false,"hasGallery":false,"hasHearkenModule":false,"hasPolis":false,"paragraphCount":4,"wordCount":160},"headData":{"title":"Career Spotlight: Developmental and Stem Cell Biology Graduate Student | KQED","description":"Elijah Martin is a graduate student in Dr. Deepak Srivastava's Lab at Gladstone Institutes where he studies how the heart develops. ","ogTitle":"","ogDescription":"","ogImgId":"","twTitle":"","twDescription":"","twImgId":"","schema":{"@context":"http://schema.org","@type":"Article","headline":"Career Spotlight: Developmental and Stem Cell Biology Graduate Student","datePublished":"2015-05-14T17:49:42.000Z","dateModified":"2015-12-19T00:01:20.000Z","image":"https://cdn.kqed.org/wp-content/uploads/2020/02/KQED-OG-Image@1x.png"}},"disqusIdentifier":"74092 http://science.kqed.org/quest/?p=74092","disqusUrl":"https://ww2.kqed.org/quest/2015/05/14/career-spotlight-developmental-and-stem-cell-biology-graduate-student/","disqusTitle":"Career Spotlight: Developmental and Stem Cell Biology Graduate Student","videoEmbed":"http://www.youtube.com/watch?v=g8a6jFrc7F4","source":"Biology","sourceUrl":"https://ww2.kqed.org/quest/category/biology/","path":"/quest/74092/career-spotlight-developmental-and-stem-cell-biology-graduate-student","audioTrackLength":null,"parsedContent":[{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003cp>\u003cem>Trouble viewing the video? Stream or download it on \u003ca href=\"http://www.pbslearningmedia.org/resource/c7e42f18-46b1-4cb8-8588-1c628a3e5b18/developmental-stem-cell-biology-graduate-student/\"> PBS LearningMedia\u003c/a>.\u003c/em>\u003cbr>\n \u003cbr>\nElijah Martin is a second-year graduate student in the \u003ca href=\"https://dscb.ucsf.edu/\">Developmental and Stem Cell Biology \u003c/a>program at University of California, San Francisco. He works in the laboratory of \u003ca href=\"http://gladstoneinstitutes.org/u/dsrivastava/SrivastavaLab.htm\">Dr. Deepak Srivastava \u003c/a>at the Gladstone Institutes. Martin studies how the heart forms to try to understand the causes of heart disease in order to develop therapies. In the lab, he grows heart cells in petri dishes, which involves mixing together different chemicals and nutrients to get the cells to grow and develop into a heart. He uses microscopes to track the growth of the cells. Since he was a young child, Martin has wanted to study the heart and he says attending graduate school will help turn his dream into a career.\u003c/p>\n\u003cp>This video is featured in our \u003cb>\u003ca href=\"http://foldscope.woop.ie/\" target=\"_blank\">Engineering Is: Diagnosing Diseases with Origami Microscopes\u003c/a>\u003c/b>e-book. You can find our other e-books at \u003ca href=\"http://blogs.kqed.org/education/e-books/\">kqed.org/ebooks\u003c/a>.\u003c/p>\n\u003cp>\u003c/p>\u003c/div>","attributes":{"named":{},"numeric":[]}},{"type":"component","content":"","name":"ad","attributes":{"named":{"label":"fullwidth"},"numeric":["fullwidth"]}},{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003c/p>\u003cp>\u003c/p>\n\u003c/div>\u003c/p>","attributes":{"named":{},"numeric":[]}}],"link":"/quest/74092/career-spotlight-developmental-and-stem-cell-biology-graduate-student","authors":["6544"],"series":["quest_13374"],"categories":["quest_4","quest_12"],"tags":["quest_13128","quest_793","quest_12946","quest_13173","quest_12269","quest_1218","quest_13172","quest_1331","quest_1332","quest_3351","quest_2349","quest_2791","quest_3025","quest_3071"],"collections":["quest_13175"],"featImg":"quest_74094","label":"source_quest_74092"},"quest_36319":{"type":"posts","id":"quest_36319","meta":{"index":"posts_1591205157","site":"quest","id":"36319","score":null,"sort":[1335897048000]},"guestAuthors":[],"slug":"rushing-to-save-heart-attack-patients","title":"Rushing to Save Heart Attack Patients","publishDate":1335897048,"format":"video","headTitle":"QUEST | KQED Science","labelTerm":{"site":"quest"},"content":"\u003cp>In our story “Rushing to Save Heart Attack Patients,” we meet Clayton resident Arlene Skuba, who survived a heart attack at 72, after doctors at the \u003ca href=\"http://www.johnmuirhealth.com/\" title=\"John Muir Medical Center\" target=\"_blank\">John Muir Medical Center in Concord\u003c/a> rapidly unclogged her arteries. \u003c/p>\n\u003cp>Just 30 years ago, doctors could only watch patients as they suffered their heart attacks. As many as 20 percent of them ended up dying. Now, by rushing patients to the operating table and opening their blocked arteries while their heart attacks are underway, they’re able to save all but 5 percent of those who make it to the hospital. \u003c/p>\n\u003cp>This success is the result of a \u003ca href=\"http://www.d2balliance.org/\" title=\"Door-to-Balloon (D2B): An Alliance for Quality national campaign\" target=\"_blank\">national campaign\u003c/a> by the \u003ca href=\"http://www.heart.org/HEARTORG/\" title=\"American Heart Association\" target=\"_blank\">American Heart Association\u003c/a>, the \u003ca href=\"http://www.cardiosource.org/acc\" title=\"American College of Cardiology\" target=\"_blank\">American College of Cardiology\u003c/a> and other groups to reduce the time it takes for the hospital to move a heart attack patient from the hospital door to the operating table. Among healthcare personnel, this is known as \u003ca href=\"http://circ.ahajournals.org/content/early/2011/08/21/CIRCULATIONAHA.111.044107\" title=\"Improvements in door-to-balloon times 2005-2010\" target=\"_blank\">“door-to-balloon” time\u003c/a>. The balloon refers to the stents cardiologists inflate inside heart attack patients’ coronary arteries to remove the clots blocking blood flow to their heart and causing their heart muscle to die.\u003c/p>\n\u003cfigure id=\"attachment_36336\" class=\"wp-caption alignleft\" style=\"max-width: 300px\">\u003ca href=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2012/04/602i_Agustin_Argenal_cardiologist_0312-12-11_GQ_resized.jpg\">\u003cimg src=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2012/04/602i_Agustin_Argenal_cardiologist_0312-12-11_GQ_resized-300x169.jpg\" alt=\"\" title=\"602i_Agustin_Argenal_cardiologist_0312-12-11_GQ_resized\" width=\"300\" height=\"169\" class=\"size-thumbnail wp-image-36336\">\u003c/a>\u003cfigcaption class=\"wp-caption-text\">Cardiologist Agustin Argenal was able to bring down the time it takes heart attack patients at John Muir Medical Center, Concord, to get from the hospital door to the operating table. Credit: Gabriela Quirós.\u003c/figcaption>\u003c/figure>\n\u003cp>“Time is muscle,” said \u003ca href=\"http://fad.johnmuirhealth.com/index.php/physician/agustin-argenal/?name=&radius=&address=&specialty=&gender=N&network=&field=lastname&latitude=&longitude=\" title=\"Dr. Agustin Argenal\" target=\"_blank\">Dr. Agustin Argenal\u003c/a>, former chief of John Muir’s catheterization lab, where heart attack patients are treated. “The longer that an artery is blocked, and thereby heart muscle is deprived of oxygen and blood flow, the more muscle is damaged and actually dies.”\u003c/p>\n\u003cp>At John Muir Medical Center in Concord, door-to-balloon time is usually under an hour, compared to the campaign’s national target of 90 minutes, said nurse Pam Lavering, coordinator for the hospital’s chest pain centers in Concord and Walnut Creek. In 2007, the hospital’s Concord campus averaged 94-minute door-to-balloon times. In the first quarter of 2012, the average was 48 minutes, said Lavering.\u003c/p>\n\u003cp>[ad fullwidth]\u003c/p>\n\u003cp>Dr. Argenal helped reduce John Muir’s door-to-balloon times by having paramedics diagnose heart attacks in the field, instead of waiting until patients arrived in the emergency room.\u003c/p>\n\u003cp>“Historically, the emergency room would evaluate the patient,” said Argenal. “If they were having a heart attack, a cardiologist would be called. A lot of time was wasted.”\u003c/p>\n\u003cp>Today, paramedics call the emergency room to let them know that they’re bringing in a heart attack patient; the emergency room calls the cardiologist and the rest of the team, and the patient is taken directly into the catheterization lab as soon as they arrive at the hospital. That way, a doctor can start removing the blockage in the patient’s arteries as soon as possible, said Dr. Argenal.\u003c/p>\n\u003cp>The last remaining challenge to getting patients onto the operating table as soon as possible is getting them to recognize that they’re having a heart attack and calling 911, he said. He offered some tips to help the public recognize \u003ca href=\"http://www.heart.org/HEARTORG/Conditions/Conditions_UCM_305346_SubHomePage.jsp\" title=\"American Heart Association's page on heart attack symptoms \" target=\"_blank\">heart attack symptoms\u003c/a>.\u003c/p>\n\u003ch2>7 Things You Might Not Know About Heart Attack Symptoms: \u003c/h2>\n\u003cp> \u003c/p>\n\u003ch3>1. The most common symptoms are quite varied. \u003c/h3>\n\u003cp>\u003c/p>\n\u003cp>The most common symptoms of a heart attack are chest tightness associated with breathlessness and perspiration; arm discomfort – classically the left arm, but it can be in both arms, and heaviness, numbness or tightness in the arms. Neck discomfort, jaw discomfort and even upper back discomfort can be symptoms too.\u003c/p>\n\u003ch3>2. People having a heart attack often don’t realize they’re having one. \u003c/h3>\n\u003cp>\u003c/p>\n\u003cp>“That’s a really major issue,” said Dr. Argenal. “So if patients could possibly recognize the symptoms, although they may not seem to be cardiac, and call 911, I think more lives would be saved.” \u003c/p>\n\u003ch3>3. People often confuse their heart attacks with indigestion, muscle skeleton pain and sore muscles.\u003c/h3>\n\u003cp>\u003c/p>\n\u003ch3>4. Even if you're in doubt, the best thing to do is to call 911.\u003c/h3>\n\u003cp>\u003c/p>\n\u003cp>“The key thing is to get to a place where the physicians can get blood tests and do an EKG,” said Dr. Argenal. “Those kinds of things really help us differentiate between something that may be innocent, and something that may be life-threatening.” \u003c/p>\n\u003cp>[box size=small align=right color=white]\u003cstrong>More in our Series\u003c/strong>\u003c/p>\n\u003cul>\n\u003cli>\u003ca href=\"http://ww2.kqed.org/quest/video/childhood-obesity-kids-fight-back/\">Childhood Obesity: Kids Fight Back\u003c/a>\u003c/li>\n\u003cli>\u003ca href=\"http://ww2.kqed.org/quest/video/pump-it-up-heart-health-special-report/\">Pump It Up: Heart Health Special Report\u003c/a>\u003c/li>\n\u003cli>\u003ca href=\"http://ww2.kqed.org/quest/video/science-on-the-spot-new-hope-for-heart-repair/\">Breakthrough Offers New Hope for Heart Repair\u003c/a>\u003c/li>\n\u003c/ul>\n\u003cp>[/box]\u003c/p>\n\u003cp>An EKG or \u003ca href=\"http://www.nhlbi.nih.gov/health/health-topics/topics/ekg/\" title=\"Definition from the National Institutes of Health\" target=\"_blank\">electrocardiogram\u003c/a> is a test by which doctors can determine the electrical output of the heart. Beating heart cells have unique electrical properties that make them similar to brain cells. These properties help them beat in unison to pump blood throughout the body. An EKG can detect areas in the heart that are being injured during a heart attack, which makes it a good diagnostic tool.\u003c/p>\n\u003cp>Ambulances are equipped with devices to perform electrocardiograms, which is why it's key to call 911 if you suspect you're having a heart attack. Driving yourself to the hospital can waste precious time and lead to more heart damage, or death.\u003c/p>\n\u003ch3>5. Doctors sometimes confuse patients’ symptoms with gall bladder disease, stomach upsets or gastritis. \u003c/h3>\n\u003cp>\u003c/p>\n\u003ch3>6. Even cardiologists can get confused by their own heart attack symptoms. \u003c/h3>\n\u003cp>\u003c/p>\n\u003cp>“I started with thumb tingling in both hands, and that led to numbness in my arms, and ultimately, after quite some time, discomfort in the chest,” said Dr. Argenal. “But I’m a cardiologist, and I was faked out. So it \u003cem>is\u003c/em> difficult for patients.” \u003c/p>\n\u003ch3>7. Women's symptoms can look different than men's.\u003c/h3>\n\u003cp>\u003c/p>\n\u003cp>\u003c/p>\n\u003cp>Women are somewhat more likely than men to experience symptoms like shortness of breath, nausea or vomiting, and back or jaw pain, according to the \u003ca href=\"http://www.heart.org/HEARTORG/\" title=\"The American Heart Association\" target=\"_blank\">American Heart Association\u003c/a>.\u003c/p>\n\n","blocks":[],"excerpt":"By rushing heart attack victims to the operating table and opening their blocked arteries while their heart attacks are underway, doctors are now able to save 95% of those who make it to the hospital.","status":"publish","parent":0,"modified":1457569788,"stats":{"hasAudio":false,"hasVideo":false,"hasChartOrMap":false,"iframeSrcs":[],"hasGoogleForm":false,"hasGallery":false,"hasHearkenModule":false,"hasPolis":false,"paragraphCount":28,"wordCount":994},"headData":{"title":"Rushing to Save Heart Attack Patients | KQED","description":"By rushing heart attack victims to the operating table and opening their blocked arteries while their heart attacks are underway, doctors are now able to save 95% of those who make it to the hospital.","ogTitle":"","ogDescription":"","ogImgId":"","twTitle":"","twDescription":"","twImgId":"","schema":{"@context":"http://schema.org","@type":"Article","headline":"Rushing to Save Heart Attack Patients","datePublished":"2012-05-01T18:30:48.000Z","dateModified":"2016-03-10T00:29:48.000Z","image":"https://cdn.kqed.org/wp-content/uploads/2020/02/KQED-OG-Image@1x.png"}},"disqusIdentifier":"36319 http://science.kqed.org/quest/video/rushing-to-save-heart-attack-patients/","disqusUrl":"https://ww2.kqed.org/quest/2012/05/01/rushing-to-save-heart-attack-patients/","disqusTitle":"Rushing to Save Heart Attack Patients","videoEmbed":"https://www.youtube.com/watch?v=CsRRbRS_jnA","path":"/quest/36319/rushing-to-save-heart-attack-patients","audioTrackLength":null,"parsedContent":[{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003cp>In our story “Rushing to Save Heart Attack Patients,” we meet Clayton resident Arlene Skuba, who survived a heart attack at 72, after doctors at the \u003ca href=\"http://www.johnmuirhealth.com/\" title=\"John Muir Medical Center\" target=\"_blank\">John Muir Medical Center in Concord\u003c/a> rapidly unclogged her arteries. \u003c/p>\n\u003cp>Just 30 years ago, doctors could only watch patients as they suffered their heart attacks. As many as 20 percent of them ended up dying. Now, by rushing patients to the operating table and opening their blocked arteries while their heart attacks are underway, they’re able to save all but 5 percent of those who make it to the hospital. \u003c/p>\n\u003cp>This success is the result of a \u003ca href=\"http://www.d2balliance.org/\" title=\"Door-to-Balloon (D2B): An Alliance for Quality national campaign\" target=\"_blank\">national campaign\u003c/a> by the \u003ca href=\"http://www.heart.org/HEARTORG/\" title=\"American Heart Association\" target=\"_blank\">American Heart Association\u003c/a>, the \u003ca href=\"http://www.cardiosource.org/acc\" title=\"American College of Cardiology\" target=\"_blank\">American College of Cardiology\u003c/a> and other groups to reduce the time it takes for the hospital to move a heart attack patient from the hospital door to the operating table. Among healthcare personnel, this is known as \u003ca href=\"http://circ.ahajournals.org/content/early/2011/08/21/CIRCULATIONAHA.111.044107\" title=\"Improvements in door-to-balloon times 2005-2010\" target=\"_blank\">“door-to-balloon” time\u003c/a>. The balloon refers to the stents cardiologists inflate inside heart attack patients’ coronary arteries to remove the clots blocking blood flow to their heart and causing their heart muscle to die.\u003c/p>\n\u003cfigure id=\"attachment_36336\" class=\"wp-caption alignleft\" style=\"max-width: 300px\">\u003ca href=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2012/04/602i_Agustin_Argenal_cardiologist_0312-12-11_GQ_resized.jpg\">\u003cimg src=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2012/04/602i_Agustin_Argenal_cardiologist_0312-12-11_GQ_resized-300x169.jpg\" alt=\"\" title=\"602i_Agustin_Argenal_cardiologist_0312-12-11_GQ_resized\" width=\"300\" height=\"169\" class=\"size-thumbnail wp-image-36336\">\u003c/a>\u003cfigcaption class=\"wp-caption-text\">Cardiologist Agustin Argenal was able to bring down the time it takes heart attack patients at John Muir Medical Center, Concord, to get from the hospital door to the operating table. Credit: Gabriela Quirós.\u003c/figcaption>\u003c/figure>\n\u003cp>“Time is muscle,” said \u003ca href=\"http://fad.johnmuirhealth.com/index.php/physician/agustin-argenal/?name=&radius=&address=&specialty=&gender=N&network=&field=lastname&latitude=&longitude=\" title=\"Dr. Agustin Argenal\" target=\"_blank\">Dr. Agustin Argenal\u003c/a>, former chief of John Muir’s catheterization lab, where heart attack patients are treated. “The longer that an artery is blocked, and thereby heart muscle is deprived of oxygen and blood flow, the more muscle is damaged and actually dies.”\u003c/p>\n\u003cp>At John Muir Medical Center in Concord, door-to-balloon time is usually under an hour, compared to the campaign’s national target of 90 minutes, said nurse Pam Lavering, coordinator for the hospital’s chest pain centers in Concord and Walnut Creek. In 2007, the hospital’s Concord campus averaged 94-minute door-to-balloon times. In the first quarter of 2012, the average was 48 minutes, said Lavering.\u003c/p>\n\u003cp>\u003c/p>\u003c/div>","attributes":{"named":{},"numeric":[]}},{"type":"component","content":"","name":"ad","attributes":{"named":{"label":"fullwidth"},"numeric":["fullwidth"]}},{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003c/p>\n\u003cp>Dr. Argenal helped reduce John Muir’s door-to-balloon times by having paramedics diagnose heart attacks in the field, instead of waiting until patients arrived in the emergency room.\u003c/p>\n\u003cp>“Historically, the emergency room would evaluate the patient,” said Argenal. “If they were having a heart attack, a cardiologist would be called. A lot of time was wasted.”\u003c/p>\n\u003cp>Today, paramedics call the emergency room to let them know that they’re bringing in a heart attack patient; the emergency room calls the cardiologist and the rest of the team, and the patient is taken directly into the catheterization lab as soon as they arrive at the hospital. That way, a doctor can start removing the blockage in the patient’s arteries as soon as possible, said Dr. Argenal.\u003c/p>\n\u003cp>The last remaining challenge to getting patients onto the operating table as soon as possible is getting them to recognize that they’re having a heart attack and calling 911, he said. He offered some tips to help the public recognize \u003ca href=\"http://www.heart.org/HEARTORG/Conditions/Conditions_UCM_305346_SubHomePage.jsp\" title=\"American Heart Association's page on heart attack symptoms \" target=\"_blank\">heart attack symptoms\u003c/a>.\u003c/p>\n\u003ch2>7 Things You Might Not Know About Heart Attack Symptoms: \u003c/h2>\n\u003cp> \u003c/p>\n\u003ch3>1. The most common symptoms are quite varied. \u003c/h3>\n\u003cp>\u003c/p>\n\u003cp>The most common symptoms of a heart attack are chest tightness associated with breathlessness and perspiration; arm discomfort – classically the left arm, but it can be in both arms, and heaviness, numbness or tightness in the arms. Neck discomfort, jaw discomfort and even upper back discomfort can be symptoms too.\u003c/p>\n\u003ch3>2. People having a heart attack often don’t realize they’re having one. \u003c/h3>\n\u003cp>\u003c/p>\n\u003cp>“That’s a really major issue,” said Dr. Argenal. “So if patients could possibly recognize the symptoms, although they may not seem to be cardiac, and call 911, I think more lives would be saved.” \u003c/p>\n\u003ch3>3. People often confuse their heart attacks with indigestion, muscle skeleton pain and sore muscles.\u003c/h3>\n\u003cp>\u003c/p>\n\u003ch3>4. Even if you're in doubt, the best thing to do is to call 911.\u003c/h3>\n\u003cp>\u003c/p>\n\u003cp>“The key thing is to get to a place where the physicians can get blood tests and do an EKG,” said Dr. Argenal. “Those kinds of things really help us differentiate between something that may be innocent, and something that may be life-threatening.” \u003c/p>\n\u003cp>[box size=small align=right color=white]\u003cstrong>More in our Series\u003c/strong>\u003c/p>\n\u003cul>\n\u003cli>\u003ca href=\"http://ww2.kqed.org/quest/video/childhood-obesity-kids-fight-back/\">Childhood Obesity: Kids Fight Back\u003c/a>\u003c/li>\n\u003cli>\u003ca href=\"http://ww2.kqed.org/quest/video/pump-it-up-heart-health-special-report/\">Pump It Up: Heart Health Special Report\u003c/a>\u003c/li>\n\u003cli>\u003ca href=\"http://ww2.kqed.org/quest/video/science-on-the-spot-new-hope-for-heart-repair/\">Breakthrough Offers New Hope for Heart Repair\u003c/a>\u003c/li>\n\u003c/ul>\n\u003cp>[/box]\u003c/p>\n\u003cp>An EKG or \u003ca href=\"http://www.nhlbi.nih.gov/health/health-topics/topics/ekg/\" title=\"Definition from the National Institutes of Health\" target=\"_blank\">electrocardiogram\u003c/a> is a test by which doctors can determine the electrical output of the heart. Beating heart cells have unique electrical properties that make them similar to brain cells. These properties help them beat in unison to pump blood throughout the body. An EKG can detect areas in the heart that are being injured during a heart attack, which makes it a good diagnostic tool.\u003c/p>\n\u003cp>Ambulances are equipped with devices to perform electrocardiograms, which is why it's key to call 911 if you suspect you're having a heart attack. Driving yourself to the hospital can waste precious time and lead to more heart damage, or death.\u003c/p>\n\u003ch3>5. Doctors sometimes confuse patients’ symptoms with gall bladder disease, stomach upsets or gastritis. \u003c/h3>\n\u003cp>\u003c/p>\n\u003ch3>6. Even cardiologists can get confused by their own heart attack symptoms. \u003c/h3>\n\u003cp>\u003c/p>\n\u003cp>“I started with thumb tingling in both hands, and that led to numbness in my arms, and ultimately, after quite some time, discomfort in the chest,” said Dr. Argenal. “But I’m a cardiologist, and I was faked out. So it \u003cem>is\u003c/em> difficult for patients.” \u003c/p>\n\u003ch3>7. Women's symptoms can look different than men's.\u003c/h3>\n\u003cp>\u003c/p>\n\u003cp>\u003c/p>\n\u003cp>Women are somewhat more likely than men to experience symptoms like shortness of breath, nausea or vomiting, and back or jaw pain, according to the \u003ca href=\"http://www.heart.org/HEARTORG/\" title=\"The American Heart Association\" target=\"_blank\">American Heart Association\u003c/a>.\u003c/p>\n\n\u003c/div>\u003c/p>","attributes":{"named":{},"numeric":[]}}],"link":"/quest/36319/rushing-to-save-heart-attack-patients","authors":["6186"],"categories":["quest_12","quest_3422","quest_3233"],"tags":["quest_11039","quest_11037","quest_11035","quest_10997","quest_11034","quest_1332","quest_11032","quest_11033","quest_11040","quest_13","quest_11036","quest_2893","quest_3071"],"featImg":"quest_36325","label":"quest"},"quest_36077":{"type":"posts","id":"quest_36077","meta":{"index":"posts_1591205157","site":"quest","id":"36077","score":null,"sort":[1335897048000]},"guestAuthors":[],"slug":"childhood-obesity-kids-fight-back","title":"Childhood Obesity: Kids Fight Back","publishDate":1335897048,"format":"video","headTitle":"QUEST | KQED Science","labelTerm":{"site":"quest"},"content":"\u003cfigure id=\"attachment_36220\" class=\"wp-caption alignleft\" style=\"max-width: 300px\">\u003ca href=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2012/04/602A_Lorena_Ramos_talk_on_reading_labels_12-7-11_GQ_resized.jpg\">\u003cimg src=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2012/04/602A_Lorena_Ramos_talk_on_reading_labels_12-7-11_GQ_resized-300x169.jpg\" alt=\"Lorena Ramos gives a talk on how to read nutritional labels at a community garden in North Oakland. Lorena is a patient at the Healthy Hearts clinic at Children's Hospital Oakland.\" title=\"602A_Lorena_Ramos_talk_on_reading_labels_12-7-11_GQ_resized\" width=\"300\" height=\"169\" class=\"size-thumbnail wp-image-36220\">\u003c/a>\u003cfigcaption class=\"wp-caption-text\">Lorena Ramos, 14, is a patient at the Healthy Hearts clinic at Children's Hospital Oakland. Credit: Gabriela Quirós.\u003c/figcaption>\u003c/figure>\n\u003cp>One in six kids in the United States is obese, a condition that doubles their risk of heart disease. Castro Valley teenager Lorena Ramos has been overweight since she was a small child. Now, with the help of her mother and the \u003ca href=\"http://www.childrenshospitaloakland.org/healthcare/depts/weight_management_healthy_hearts.asp\" title=\"Healthy Hearts clinic at Children's Hospital Oakland\" target=\"_blank\">Healthy Hearts clinic at Children’s Hospital Oakland\u003c/a>, she’s fighting to exercise, eat healthily and drop weight. Will she succeed? Watch our story to find out. \u003c/p>\n\u003cp>The staff at the Healthy Hearts clinic had useful advice for parents. Here's a list I came up with.\u003c/p>\n\u003cp>\u003cbr clear=\"all\">\u003c/p>\n\u003ch2>7 Things I Learned About How to Help Your Kid Keep a Healthy Weight:\u003c/h2>\n\u003cp> \u003c/p>\n\u003ch3>1. Serve appropriate portions. \u003c/h3>\n\u003cp>\u003c/p>\n\u003cp>[ad fullwidth]\u003c/p>\n\u003cp>“Half of your plate should be fruits and/or vegetables, a quarter of your plate is your protein, and the remaining quarter is your whole grains – things like rice or pasta,” said Dr. Lydia Tinajero-Deck, co-director of the Healthy Hearts clinic.\u003c/p>\n\u003cp>The portion of whole grains should be about the size of a fist, she said. This can sometimes be surprising for kids and parents used to covering their plate with rice or pasta and placing the protein or veggies on top. A serving of meat should be about the size of the palm of a hand.\u003c/p>\n\u003ch3>2. Try to have some meatless meals.\u003c/h3>\n\u003cp>\u003c/p>\n\u003cp>Marin County cardiologist \u003ca href=\"http://www.pmri.org/dean_ornish.html\" target=\"_blank\">Dean Ornish\u003c/a> found in the mid-80s that a low-fat vegetarian diet, together with stress management and exercise, could reverse heart disease. But during our interview, he repeated over and over again that it’s not all or nothing – you don’t have to go vegan to be healthy. \u003c/p>\n\u003ch3>3. If you and your family go vegetarian, make sure you don’t eat too much cheese.\u003c/h3>\n\u003cp>\u003c/p>\n\u003cp>“A lot of times, especially with our teen girls on a vegetarian diet, there’s a compensation with extra cheese,” said Dr. June Tester, co-director of the Healthy Hearts clinic, “and they end up actually, ironically, introducing a lot more saturated fat.” \u003c/p>\n\u003ch3>4. Lobby for more and better physical education in schools, healthier school lunches and summer programs for kids.\u003c/h3>\n\u003cp>\u003c/p>\n\u003cp>“I wish for kids to play for an hour every day at school. It will help them academically as well as help their little bodies not gain so much weight,” said Dr. Tinajero-Deck. “And we can feed kids a lot better in schools. Oh, my goodness, we can do so much better.”\u003c/p>\n\u003cp>After Dr. Tinajero-Deck suggested to a group of dietitians at the Oakland Unified School District that milk or water were better choices than juice for breakfast, they went ahead and modified their menu.\u003c/p>\n\u003cp>\u003cstrong>More in our Series\u003c/strong>\u003c/p>\n\u003cul>\n\u003cli>\u003ca href=\"http://ww2.kqed.org/quest/video/rushing-to-save-heart-attack-patients/\">Rushing to Save Heart Attack Patients\u003c/a>\u003c/li>\n\u003cli>\u003ca href=\"http://ww2.kqed.org/quest/video/pump-it-up-heart-health-special-report/\">Pump It Up: Heart Health Special Report\u003c/a>\u003c/li>\n\u003cli>\u003ca href=\"http://ww2.kqed.org/quest/video/science-on-the-spot-new-hope-for-heart-repair/\">Breakthrough Offers New Hope for Heart Repair\u003c/a>\u003c/li>\n\u003c/ul>\n\u003ch3>5. Give your kid the gift of movement. \u003c/h3>\n\u003cp>\u003c/p>\n\u003cp>“Jumping rope 5 to 10 minutes, four days a week, is great exercise,” said Tess Barbieri, the exercise physiologist at the Healthy Hearts clinic. “You get a lot of bang for your buck.” She also recommends things as simple as bouncing a ball back and forth, or tossing bean bags and skipping to retrieve them. \u003c/p>\n\u003ch3>6. Help your child find their life-long exercise. \u003c/h3>\n\u003cp>\u003c/p>\n\u003cp>Some kids like to ride a bike or rollerblade; others prefer to go on a walk with their friends. The important thing is to get moving and to make moving a habit. \u003c/p>\n\u003cp>“You really have to teach kids at a young age that movement is just a part of their lives,” said Dr. Tinajero-Deck. \u003c/p>\n\u003ch3>7. Find someone for your kid to exercise with. \u003c/h3>\n\u003cp>\u003c/p>\n\u003cp>Sometimes kids won’t exercise with a parent. Or parents don’t have time (imagine that!). \u003c/p>\n\u003cp>“Try to figure out who’s going to be that motivator for your kid,” said Dr. Tinajero-Deck. “Maybe a best friend.”\u003c/p>\n\u003cp>\u003c/p>\n\u003cp>You can also find out more about obesity prevention in a related post from KQED's \u003ca href=\"http://blogs.kqed.org/stateofhealth\">State of Health\u003c/a> blog, \u003ca href=\"http://blogs.kqed.org/stateofhealth/2012/05/07/lessons-learned-from-the-war-on-smoking-applied-to-obesity/\">Lessons Learned from the War on Smoking, Applied to Obesity\u003c/a>.\u003c/p>\n\n","blocks":[],"excerpt":"One in six kids in the United States is obese, a condition that doubles their risk of heart disease. Lorena Ramos, 14, a patient at the Healthy Hearts clinic at Children's Hospital Oakland struggles to lose weight. Will she succeed?","status":"publish","parent":0,"modified":1457569910,"stats":{"hasAudio":false,"hasVideo":false,"hasChartOrMap":false,"iframeSrcs":[],"hasGoogleForm":false,"hasGallery":false,"hasHearkenModule":false,"hasPolis":false,"paragraphCount":26,"wordCount":713},"headData":{"title":"Childhood Obesity: Kids Fight Back | KQED","description":"One in six kids in the United States is obese, a condition that doubles their risk of heart disease. Lorena Ramos, 14, a patient at the Healthy Hearts clinic at Children's Hospital Oakland struggles to lose weight. Will she succeed?","ogTitle":"","ogDescription":"","ogImgId":"","twTitle":"","twDescription":"","twImgId":"","schema":{"@context":"http://schema.org","@type":"Article","headline":"Childhood Obesity: Kids Fight Back","datePublished":"2012-05-01T18:30:48.000Z","dateModified":"2016-03-10T00:31:50.000Z","image":"https://cdn.kqed.org/wp-content/uploads/2020/02/KQED-OG-Image@1x.png"}},"disqusIdentifier":"36077 http://science.kqed.org/quest/?post_type=videos&p=36077","disqusUrl":"https://ww2.kqed.org/quest/2012/05/01/childhood-obesity-kids-fight-back/","disqusTitle":"Childhood Obesity: Kids Fight Back","videoEmbed":"https://www.youtube.com/watch?v=JytPFOfOtdg","path":"/quest/36077/childhood-obesity-kids-fight-back","audioTrackLength":null,"parsedContent":[{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003cfigure id=\"attachment_36220\" class=\"wp-caption alignleft\" style=\"max-width: 300px\">\u003ca href=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2012/04/602A_Lorena_Ramos_talk_on_reading_labels_12-7-11_GQ_resized.jpg\">\u003cimg src=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2012/04/602A_Lorena_Ramos_talk_on_reading_labels_12-7-11_GQ_resized-300x169.jpg\" alt=\"Lorena Ramos gives a talk on how to read nutritional labels at a community garden in North Oakland. Lorena is a patient at the Healthy Hearts clinic at Children's Hospital Oakland.\" title=\"602A_Lorena_Ramos_talk_on_reading_labels_12-7-11_GQ_resized\" width=\"300\" height=\"169\" class=\"size-thumbnail wp-image-36220\">\u003c/a>\u003cfigcaption class=\"wp-caption-text\">Lorena Ramos, 14, is a patient at the Healthy Hearts clinic at Children's Hospital Oakland. Credit: Gabriela Quirós.\u003c/figcaption>\u003c/figure>\n\u003cp>One in six kids in the United States is obese, a condition that doubles their risk of heart disease. Castro Valley teenager Lorena Ramos has been overweight since she was a small child. Now, with the help of her mother and the \u003ca href=\"http://www.childrenshospitaloakland.org/healthcare/depts/weight_management_healthy_hearts.asp\" title=\"Healthy Hearts clinic at Children's Hospital Oakland\" target=\"_blank\">Healthy Hearts clinic at Children’s Hospital Oakland\u003c/a>, she’s fighting to exercise, eat healthily and drop weight. Will she succeed? Watch our story to find out. \u003c/p>\n\u003cp>The staff at the Healthy Hearts clinic had useful advice for parents. Here's a list I came up with.\u003c/p>\n\u003cp>\u003cbr clear=\"all\">\u003c/p>\n\u003ch2>7 Things I Learned About How to Help Your Kid Keep a Healthy Weight:\u003c/h2>\n\u003cp> \u003c/p>\n\u003ch3>1. Serve appropriate portions. \u003c/h3>\n\u003cp>\u003c/p>\n\u003cp>\u003c/p>\u003c/div>","attributes":{"named":{},"numeric":[]}},{"type":"component","content":"","name":"ad","attributes":{"named":{"label":"fullwidth"},"numeric":["fullwidth"]}},{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003c/p>\n\u003cp>“Half of your plate should be fruits and/or vegetables, a quarter of your plate is your protein, and the remaining quarter is your whole grains – things like rice or pasta,” said Dr. Lydia Tinajero-Deck, co-director of the Healthy Hearts clinic.\u003c/p>\n\u003cp>The portion of whole grains should be about the size of a fist, she said. This can sometimes be surprising for kids and parents used to covering their plate with rice or pasta and placing the protein or veggies on top. A serving of meat should be about the size of the palm of a hand.\u003c/p>\n\u003ch3>2. Try to have some meatless meals.\u003c/h3>\n\u003cp>\u003c/p>\n\u003cp>Marin County cardiologist \u003ca href=\"http://www.pmri.org/dean_ornish.html\" target=\"_blank\">Dean Ornish\u003c/a> found in the mid-80s that a low-fat vegetarian diet, together with stress management and exercise, could reverse heart disease. But during our interview, he repeated over and over again that it’s not all or nothing – you don’t have to go vegan to be healthy. \u003c/p>\n\u003ch3>3. If you and your family go vegetarian, make sure you don’t eat too much cheese.\u003c/h3>\n\u003cp>\u003c/p>\n\u003cp>“A lot of times, especially with our teen girls on a vegetarian diet, there’s a compensation with extra cheese,” said Dr. June Tester, co-director of the Healthy Hearts clinic, “and they end up actually, ironically, introducing a lot more saturated fat.” \u003c/p>\n\u003ch3>4. Lobby for more and better physical education in schools, healthier school lunches and summer programs for kids.\u003c/h3>\n\u003cp>\u003c/p>\n\u003cp>“I wish for kids to play for an hour every day at school. It will help them academically as well as help their little bodies not gain so much weight,” said Dr. Tinajero-Deck. “And we can feed kids a lot better in schools. Oh, my goodness, we can do so much better.”\u003c/p>\n\u003cp>After Dr. Tinajero-Deck suggested to a group of dietitians at the Oakland Unified School District that milk or water were better choices than juice for breakfast, they went ahead and modified their menu.\u003c/p>\n\u003cp>\u003cstrong>More in our Series\u003c/strong>\u003c/p>\n\u003cul>\n\u003cli>\u003ca href=\"http://ww2.kqed.org/quest/video/rushing-to-save-heart-attack-patients/\">Rushing to Save Heart Attack Patients\u003c/a>\u003c/li>\n\u003cli>\u003ca href=\"http://ww2.kqed.org/quest/video/pump-it-up-heart-health-special-report/\">Pump It Up: Heart Health Special Report\u003c/a>\u003c/li>\n\u003cli>\u003ca href=\"http://ww2.kqed.org/quest/video/science-on-the-spot-new-hope-for-heart-repair/\">Breakthrough Offers New Hope for Heart Repair\u003c/a>\u003c/li>\n\u003c/ul>\n\u003ch3>5. Give your kid the gift of movement. \u003c/h3>\n\u003cp>\u003c/p>\n\u003cp>“Jumping rope 5 to 10 minutes, four days a week, is great exercise,” said Tess Barbieri, the exercise physiologist at the Healthy Hearts clinic. “You get a lot of bang for your buck.” She also recommends things as simple as bouncing a ball back and forth, or tossing bean bags and skipping to retrieve them. \u003c/p>\n\u003ch3>6. Help your child find their life-long exercise. \u003c/h3>\n\u003cp>\u003c/p>\n\u003cp>Some kids like to ride a bike or rollerblade; others prefer to go on a walk with their friends. The important thing is to get moving and to make moving a habit. \u003c/p>\n\u003cp>“You really have to teach kids at a young age that movement is just a part of their lives,” said Dr. Tinajero-Deck. \u003c/p>\n\u003ch3>7. Find someone for your kid to exercise with. \u003c/h3>\n\u003cp>\u003c/p>\n\u003cp>Sometimes kids won’t exercise with a parent. Or parents don’t have time (imagine that!). \u003c/p>\n\u003cp>“Try to figure out who’s going to be that motivator for your kid,” said Dr. Tinajero-Deck. “Maybe a best friend.”\u003c/p>\n\u003cp>\u003c/p>\n\u003cp>You can also find out more about obesity prevention in a related post from KQED's \u003ca href=\"http://blogs.kqed.org/stateofhealth\">State of Health\u003c/a> blog, \u003ca href=\"http://blogs.kqed.org/stateofhealth/2012/05/07/lessons-learned-from-the-war-on-smoking-applied-to-obesity/\">Lessons Learned from the War on Smoking, Applied to Obesity\u003c/a>.\u003c/p>\n\n\u003c/div>\u003c/p>","attributes":{"named":{},"numeric":[]}}],"link":"/quest/36077/childhood-obesity-kids-fight-back","authors":["6186"],"categories":["quest_12","quest_3422","quest_3233"],"tags":["quest_11027","quest_11029","quest_1035","quest_11028","quest_1332","quest_2031","quest_2095","quest_13","quest_2893","quest_3071"],"featImg":"quest_36210","label":"quest"},"quest_36263":{"type":"posts","id":"quest_36263","meta":{"index":"posts_1591205157","site":"quest","id":"36263","score":null,"sort":[1335897020000]},"guestAuthors":[],"slug":"pump-it-up-heart-health-special-report","title":"Pump It Up: Heart Health Special Report","publishDate":1335897020,"format":"video","headTitle":"QUEST | KQED Science","labelTerm":{"site":"quest"},"content":"\u003cp>The three stories in the half-hour QUEST TV show \u003cstrong>Pump It Up: Heart Health Special Report\u003c/strong> investigate the number one cause of death in America, heart disease, which kills 600,000 people each year – more than die from cancer, car accidents or AIDS. We look at the disease from the point of view of a teenager trying to lower her risk; a heart attack patient and the team that saved her life, and a researcher working to one day rebuild a damaged heart from the inside out.\u003c/p>\n\u003cfigure id=\"attachment_36372\" class=\"wp-caption alignright\" style=\"max-width: 300px\">\u003ca href=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2012/04/602A_Lorena_Ramos_talk_on_reading_labels_12-7-11_GQ_resized1.jpg\">\u003cimg src=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2012/04/602A_Lorena_Ramos_talk_on_reading_labels_12-7-11_GQ_resized1-300x169.jpg\" alt=\"\" title=\"602A_Lorena_Ramos_talk_on_reading_labels_12-7-11_GQ_resized\" width=\"300\" height=\"169\" class=\"size-thumbnail wp-image-36372\">\u003c/a>\u003cfigcaption class=\"wp-caption-text\">Lorena Ramos, 14, struggles to lose weight.\u003c/figcaption>\u003c/figure>\n\u003cp>The show opens with the 14-minute story \u003cstrong>\u003ca href=\"http://ww2.kqed.org/quest/video/childhood-obesity-kids-fight-back/\">Childhood Obesity: Kids Fight Back\u003c/a>\u003c/strong>. One in six kids in the United States is obese, a condition that doubles their risk of heart disease. Castro Valley teenager Lorena Ramos, 14, has been overweight since she was a small child. Now, with the help of her mother and the \u003ca href=\"http://www.childrenshospitaloakland.org/healthcare/depts/weight_management_healthy_hearts.asp\" title=\"Healthy Hearts clinic at Children's Hospital Oakland\" target=\"_blank\">Healthy Hearts clinic at Children’s Hospital Oakland\u003c/a>, she’s fighting to exercise, eat healthily and drop weight. Will she succeed?\u003c/p>\n\u003cp>\u003c/p>\n\u003cfigure id=\"attachment_36382\" class=\"wp-caption alignleft\" style=\"max-width: 300px\">\u003ca href=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2012/04/602i_Angiogram_16_12-28-11_GQ_NICE_resized1.jpg\">\u003cimg src=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2012/04/602i_Angiogram_16_12-28-11_GQ_NICE_resized1-300x169.jpg\" alt=\"A heart patient is treated at John Muir Medical Center in Concord.\" title=\"602i_Angiogram_16_12-28-11_GQ_NICE_resized\" width=\"300\" height=\"169\" class=\"size-thumbnail wp-image-36382\">\u003c/a>\u003cfigcaption class=\"wp-caption-text\">A heart patient is treated at John Muir Medical Center in Concord.\u003c/figcaption>\u003c/figure>\n\u003cp>\u003cstrong>\u003ca href=\"http://ww2.kqed.org/quest/video/rushing-to-save-heart-attack-patients/\">Rushing to Save Heart Attack Patients\u003c/a>\u003c/strong> tells the story of Arlene Skuba, who survived a heart attack at 72, after doctors at the \u003ca href=\"http://www.johnmuirhealth.com/locations/john-muir-medical-center-concord.html\" title=\"John Muir Medical Center, Concord\" target=\"_blank\">John Muir Medical Center in Concord\u003c/a> rapidly unclogged her arteries. Just 30 years ago, doctors could only watch patients as they suffered their heart attacks. As many as 20 percent of them ended up dying. Now, by opening their blocked arteries while their heart attacks are underway, they save all but 5 percent of those who make it to a hospital.\u003c/p>\n\u003cfigure id=\"attachment_36266\" class=\"wp-caption alignright\" style=\"max-width: 300px\">\u003ca href=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2012/04/602B_Yu_Huang_holds_research_mouse_CU_resized1.jpg\">\u003cimg src=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2012/04/602B_Yu_Huang_holds_research_mouse_CU_resized1-300x169.jpg\" alt=\"Research mouse.\" title=\"602B_Yu_Huang_holds_research_mouse_CU_resized\" width=\"300\" height=\"169\" class=\"size-thumbnail wp-image-36266\">\u003c/a>\u003cfigcaption class=\"wp-caption-text\">After being injected with three genes, the hearts of mice who had suffered a heart attack pumped blood normally. All photos by Gabriela Quirós.\u003c/figcaption>\u003c/figure>\n\u003cp>The special report’s final 4-minute story, \u003cstrong>\u003ca href=\"http://ww2.kqed.org/quest/video/science-on-the-spot-new-hope-for-heart-repair/\" title=\"Breakthrough Offers New Hope for Heart Repair\" target=\"_blank\">New Hope for Heart Repair\u003c/a>\u003c/strong>, takes us into the future, to a time when a single injection of three genes might be able to repair damaged hearts and give heart attack survivors their quality of life back. We visit the \u003ca href=\"http://www.gladstone.ucsf.edu/gladstone/site/gweb1/\" title=\"The Gladstone Institutes\" target=\"_blank\">Gladstone Institutes\u003c/a>, in San Francisco, and watch as researchers repair tiny mice hearts using the next generation of cell reprogramming. \u003c/p>\n\u003cp>[ad fullwidth]\u003c/p>\n\u003cp>\u003cbr clear=\"all\">\u003c/p>\n\u003cp>\u003c/p>\n\u003cp>\u003cstrong>You can watch each of the three stories individually, as well, by following the links below:\u003c/strong> \u003c/p>\n\n","blocks":[],"excerpt":"This half-hour program looks at heart disease – the number one killer in the United States – from the point of view of a teenager trying to lower her risk, a heart attack survivor, and a scientist working to rebuild damaged hearts.","status":"publish","parent":0,"modified":1457569719,"stats":{"hasAudio":false,"hasVideo":false,"hasChartOrMap":false,"iframeSrcs":[],"hasGoogleForm":false,"hasGallery":false,"hasHearkenModule":false,"hasPolis":false,"paragraphCount":9,"wordCount":384},"headData":{"title":"Pump It Up: Heart Health Special Report | KQED","description":"This half-hour program looks at heart disease – the number one killer in the United States – from the point of view of a teenager trying to lower her risk, a heart attack survivor, and a scientist working to rebuild damaged hearts.","ogTitle":"","ogDescription":"","ogImgId":"","twTitle":"","twDescription":"","twImgId":"","schema":{"@context":"http://schema.org","@type":"Article","headline":"Pump It Up: Heart Health Special Report","datePublished":"2012-05-01T18:30:20.000Z","dateModified":"2016-03-10T00:28:39.000Z","image":"https://cdn.kqed.org/wp-content/uploads/2020/02/KQED-OG-Image@1x.png"}},"disqusIdentifier":"36263 http://science.kqed.org/quest/?post_type=videos&p=36263","disqusUrl":"https://ww2.kqed.org/quest/2012/05/01/pump-it-up-heart-health-special-report/","disqusTitle":"Pump It Up: Heart Health Special Report","videoEmbed":"https://www.youtube.com/watch?v=NbfKYZ9UTwU","path":"/quest/36263/pump-it-up-heart-health-special-report","audioTrackLength":null,"parsedContent":[{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003cp>The three stories in the half-hour QUEST TV show \u003cstrong>Pump It Up: Heart Health Special Report\u003c/strong> investigate the number one cause of death in America, heart disease, which kills 600,000 people each year – more than die from cancer, car accidents or AIDS. We look at the disease from the point of view of a teenager trying to lower her risk; a heart attack patient and the team that saved her life, and a researcher working to one day rebuild a damaged heart from the inside out.\u003c/p>\n\u003cfigure id=\"attachment_36372\" class=\"wp-caption alignright\" style=\"max-width: 300px\">\u003ca href=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2012/04/602A_Lorena_Ramos_talk_on_reading_labels_12-7-11_GQ_resized1.jpg\">\u003cimg src=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2012/04/602A_Lorena_Ramos_talk_on_reading_labels_12-7-11_GQ_resized1-300x169.jpg\" alt=\"\" title=\"602A_Lorena_Ramos_talk_on_reading_labels_12-7-11_GQ_resized\" width=\"300\" height=\"169\" class=\"size-thumbnail wp-image-36372\">\u003c/a>\u003cfigcaption class=\"wp-caption-text\">Lorena Ramos, 14, struggles to lose weight.\u003c/figcaption>\u003c/figure>\n\u003cp>The show opens with the 14-minute story \u003cstrong>\u003ca href=\"http://ww2.kqed.org/quest/video/childhood-obesity-kids-fight-back/\">Childhood Obesity: Kids Fight Back\u003c/a>\u003c/strong>. One in six kids in the United States is obese, a condition that doubles their risk of heart disease. Castro Valley teenager Lorena Ramos, 14, has been overweight since she was a small child. Now, with the help of her mother and the \u003ca href=\"http://www.childrenshospitaloakland.org/healthcare/depts/weight_management_healthy_hearts.asp\" title=\"Healthy Hearts clinic at Children's Hospital Oakland\" target=\"_blank\">Healthy Hearts clinic at Children’s Hospital Oakland\u003c/a>, she’s fighting to exercise, eat healthily and drop weight. Will she succeed?\u003c/p>\n\u003cp>\u003c/p>\n\u003cfigure id=\"attachment_36382\" class=\"wp-caption alignleft\" style=\"max-width: 300px\">\u003ca href=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2012/04/602i_Angiogram_16_12-28-11_GQ_NICE_resized1.jpg\">\u003cimg src=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2012/04/602i_Angiogram_16_12-28-11_GQ_NICE_resized1-300x169.jpg\" alt=\"A heart patient is treated at John Muir Medical Center in Concord.\" title=\"602i_Angiogram_16_12-28-11_GQ_NICE_resized\" width=\"300\" height=\"169\" class=\"size-thumbnail wp-image-36382\">\u003c/a>\u003cfigcaption class=\"wp-caption-text\">A heart patient is treated at John Muir Medical Center in Concord.\u003c/figcaption>\u003c/figure>\n\u003cp>\u003cstrong>\u003ca href=\"http://ww2.kqed.org/quest/video/rushing-to-save-heart-attack-patients/\">Rushing to Save Heart Attack Patients\u003c/a>\u003c/strong> tells the story of Arlene Skuba, who survived a heart attack at 72, after doctors at the \u003ca href=\"http://www.johnmuirhealth.com/locations/john-muir-medical-center-concord.html\" title=\"John Muir Medical Center, Concord\" target=\"_blank\">John Muir Medical Center in Concord\u003c/a> rapidly unclogged her arteries. Just 30 years ago, doctors could only watch patients as they suffered their heart attacks. As many as 20 percent of them ended up dying. Now, by opening their blocked arteries while their heart attacks are underway, they save all but 5 percent of those who make it to a hospital.\u003c/p>\n\u003cfigure id=\"attachment_36266\" class=\"wp-caption alignright\" style=\"max-width: 300px\">\u003ca href=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2012/04/602B_Yu_Huang_holds_research_mouse_CU_resized1.jpg\">\u003cimg src=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2012/04/602B_Yu_Huang_holds_research_mouse_CU_resized1-300x169.jpg\" alt=\"Research mouse.\" title=\"602B_Yu_Huang_holds_research_mouse_CU_resized\" width=\"300\" height=\"169\" class=\"size-thumbnail wp-image-36266\">\u003c/a>\u003cfigcaption class=\"wp-caption-text\">After being injected with three genes, the hearts of mice who had suffered a heart attack pumped blood normally. All photos by Gabriela Quirós.\u003c/figcaption>\u003c/figure>\n\u003cp>The special report’s final 4-minute story, \u003cstrong>\u003ca href=\"http://ww2.kqed.org/quest/video/science-on-the-spot-new-hope-for-heart-repair/\" title=\"Breakthrough Offers New Hope for Heart Repair\" target=\"_blank\">New Hope for Heart Repair\u003c/a>\u003c/strong>, takes us into the future, to a time when a single injection of three genes might be able to repair damaged hearts and give heart attack survivors their quality of life back. We visit the \u003ca href=\"http://www.gladstone.ucsf.edu/gladstone/site/gweb1/\" title=\"The Gladstone Institutes\" target=\"_blank\">Gladstone Institutes\u003c/a>, in San Francisco, and watch as researchers repair tiny mice hearts using the next generation of cell reprogramming. \u003c/p>\n\u003cp>\u003c/p>\u003c/div>","attributes":{"named":{},"numeric":[]}},{"type":"component","content":"","name":"ad","attributes":{"named":{"label":"fullwidth"},"numeric":["fullwidth"]}},{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003c/p>\n\u003cp>\u003cbr clear=\"all\">\u003c/p>\n\u003cp>\u003c/p>\n\u003cp>\u003cstrong>You can watch each of the three stories individually, as well, by following the links below:\u003c/strong> \u003c/p>\n\n\u003c/div>\u003c/p>","attributes":{"named":{},"numeric":[]}}],"link":"/quest/36263/pump-it-up-heart-health-special-report","authors":["6186"],"categories":["quest_12","quest_3422","quest_3233"],"tags":["quest_10999","quest_11027","quest_11029","quest_1189","quest_1218","quest_1331","quest_10997","quest_1332","quest_11032","quest_2031","quest_2095","quest_13","quest_2893","quest_3314","quest_3071"],"featImg":"quest_36367","label":"quest"},"quest_35176":{"type":"posts","id":"quest_35176","meta":{"index":"posts_1591205157","site":"quest","id":"35176","score":null,"sort":[1334768406000]},"guestAuthors":[],"slug":"science-on-the-spot-new-hope-for-heart-repair","title":"Science on the SPOT: New Hope for Heart Repair","publishDate":1334768406,"format":"video","headTitle":"Science on the SPOT | QUEST | KQED Science","labelTerm":{"term":3296,"site":"quest"},"content":"\u003cp>More than 5 million people in the United States live with damaged hearts that make it difficult to walk and carry out other simple daily tasks. Pacemakers and drugs can help, but they don’t repair the heart muscle that has died as a result of a heart attack or clogged arteries.\u003c/p>\n\u003cp>Now, scientists in San Francisco say a more effective treatment might be on the way. \u003c/p>\n\u003cfigure id=\"attachment_35476\" class=\"wp-caption alignleft\" style=\"max-width: 300px\">\u003ca href=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2012/04/602B_Yu_Huang_holds_research_mouse_CU_resized.jpg\">\u003cimg src=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2012/04/602B_Yu_Huang_holds_research_mouse_CU_resized-300x169.jpg\" alt=\"Research mouse\" title=\"602B_Yu_Huang_holds_research_mouse_CU_resized\" width=\"300\" height=\"169\" class=\"size-thumbnail wp-image-35476\">\u003c/a>\u003cfigcaption class=\"wp-caption-text\">Three months after being injected with three genes, the hearts of mice that had suffered a heart attack pumped as much blood as a normal heart. Credit: Gabriela Quirós, QUEST \u003c/figcaption>\u003c/figure>\n\u003cp>The researchers from the \u003ca href=\"http://www.gladstone.ucsf.edu/gladstone/site/gweb1/\" title=\"The Gladstone Institutes\" target=\"_blank\">Gladstone Institutes\u003c/a>, affiliated with the University of California-San Francisco, reported today that using a new genetic technique, they have succeeded for the first time in repairing, from within, the hearts of mice weakened by heart attacks. \u003c/p>\n\u003cp>“There are a variety of approaches we use right now to help people who are left with damaged hearts,” said \u003ca href=\"http://www.gladstone.ucsf.edu/gladstone/site/srivastava/\" title=\"Dr. Deepak Srivastava\" target=\"_blank\">Dr. Deepak Srivastava\u003c/a>, senior author of the paper and director of cardiovascular research at the Gladstone Institutes, “but none of them actually get to the root of the problem, which is replacing that damaged heart muscle. And that’s where our focus has been.”\u003c/p>\n\u003cp>The scientists injected three genes into the hearts of research mice that had been given mild heart attacks. Within three months, the genes transformed non-beating cells in the heart into cells that looked and acted just like beating heart muscle cells. These new beating cells restored the heart’s ability to pump blood to the rest of the body. \u003c/p>\n\u003cp>[ad fullwidth]\u003c/p>\n\u003cp>Human hearts have billions of non-beating cells, which support the beating cells by forming the heart’s structure, Srivastava said. Mice have millions of these support cells too. When a heart attack happens, the support cells rush to the site of the damage and form scar tissue, which preserves the heart’s structure, but doesn’t help it pump blood. \u003c/p>\n\u003cp>“We’ve found a way to take these support cells that should normally never become muscle, and convert them into new muscle cells that actually integrate with the rest of the heart, contribute to the force that it generates, and allow us to regenerate the heart from within the organ itself,” said Srivastava.\u003c/p>\n\u003cfigure id=\"attachment_35482\" class=\"wp-caption alignright\" style=\"max-width: 300px\">\u003ca href=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2012/04/yellow-induced-muscle-cells-with-sarcomere-structure_resized.jpg\">\u003cimg src=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2012/04/yellow-induced-muscle-cells-with-sarcomere-structure_resized-300x169.jpg\" alt=\"Mouse heart muscle cells created by Gladstone Institutes researchers.\" title=\"yellow induced muscle cells with sarcomere structure_resized\" width=\"300\" height=\"169\" class=\"size-thumbnail wp-image-35482\">\u003c/a>\u003cfigcaption class=\"wp-caption-text\">Non-beating heart cells became beating heart cells like these. Credit: Li Qian, Gladstone Institutes \u003c/figcaption>\u003c/figure>\n\u003cp>The new research appears in the April 18 online edition of the journal \u003ca href=\"http://www.nature.com/nature/index.html\" title=\"Journal Nature\" target=\"_blank\">Nature\u003c/a> and was led by \u003ca href=\"http://www.gladstone.ucsf.edu/gladstone/site/publicaffairs/content/1/736\" title=\"Li Qian wins prestigious award\" target=\"_blank\">Li Qian\u003c/a>, also from the Gladstone Institutes.\u003c/p>\n\u003cp>Heart attacks and other heart disease kill 600,000 people each year. Many more survive, yet lead diminished lives. Some 5.7 million people live with damaged hearts that pump less blood, making it difficult for them to climb a flight of stairs or walk across a parking lot. \u003c/p>\n\u003cp>During a heart attack, clots block one or several coronary arteries and cut off blood flow. By rushing patients to the operating table and unclogging their arteries with catheters and stents, doctors are able to save all but 5 percent of victims who make it to the hospital. \u003c/p>\n\u003cp>“While we’ve been doing better at saving lives, each time we save a life the patient still loses some of their muscle,” Srivastava said. “So the number of people who are left with damaged hearts is actually growing, even though the number of people who die from heart attacks is getting smaller.”\u003c/p>\n\u003cp>Treatments for humans could be six to seven years away, he added. The next step will be to test the treatment on pigs. Scientists still need to figure out if cell reprogramming is safe for humans; how to deliver the genes into the heart, and how to produce enough new beating heart cells to repair a human – rather than a mouse – heart.\u003c/p>\n\u003cp>\u003cstrong>More in our Series\u003c/strong>\u003c/p>\n\u003cul>\n\u003cli>\u003ca href=\"http://ww2.kqed.org/quest/video/childhood-obesity-kids-fight-back/\">Childhood Obesity: Kids Fight Back\u003c/a>\u003c/li>\n\u003cli>\u003ca href=\"http://ww2.kqed.org/quest/video/pump-it-up-heart-health-special-report/\">Pump It Up: Heart Health Special Report\u003c/a>\u003c/li>\n\u003cli>\u003ca href=\"http://ww2.kqed.org/quest/video/rushing-to-save-heart-attack-patients/\">Rushing to Save Heart Attack Patients\u003c/a>\u003c/li>\n\u003c/ul>\n\u003cp>Nevertheless, the research is drawing the attention of other heart researchers.\u003c/p>\n\u003cp>“It’s a major discovery and certainly suggests a new approach to treat injury that previously had been thought to be irreversible,” said \u003ca href=\"http://www.cedars-sinai.edu/Bios---Physician/H-O/Eduardo-Marban-MD.aspx\" title=\"Dr. Eduardo Marban\" target=\"_blank\">Dr. Eduardo Marbán\u003c/a>, director of the \u003ca href=\"http://www.cedars-sinai.edu/Patients/Programs-and-Services/Heart-Institute/\" title=\"Cedars-Sinai Heart Institute\" target=\"_blank\">Cedars-Sinai Heart Institute\u003c/a> in Los Angeles.\u003c/p>\n\u003cp>Marbán said it’s been “a long-held dogma” that once scar tissue has formed in the heart, it can’t change into heart muscle. This finding in mice, and recent research by Marbán’s team on a small group of human patients, challenge that belief, he said.\u003c/p>\n\u003cp>Although the cell reprogramming research doesn’t involve stem cells, the Gladstone scientists used techniques that were discovered through stem cell research. \u003c/p>\n\u003cp>The scientists said their work was inspired by the discovery in 2007 that a few genes can transform an adult skin cell into a cell with the properties of a human embryonic stem cell. Researchers have been intensely interested in \u003ca href=\"http://ww2.kqed.org/quest/video/stem-cell-gold-rush/\" title=\"QUEST TV segment about stem cell research in California\" target=\"_blank\">embryonic stem cells\u003c/a> as a possible source of treatments for diseases like Parkinson’s because they can be coaxed to turn into virtually any type of cell in the body. But because embryonic stem cells are plucked from embryos left over from fertility treatments, and require the destruction of these embryos, their study has been controversial.\u003c/p>\n\u003cp>An alternative to embryonic stem cells came with the skin cell breakthrough five years ago. Then, \u003ca href=\"http://www.gladstone.ucsf.edu/gladstone/site/yamanaka/\" title=\"Dr. Shinya Yamanaka\" target=\"_blank\">Dr. Shinya Yamanaka\u003c/a>, of the Gladstone Institutes and Kyoto University in Japan, inserted four genes that are present in embryonic stem cells into adult skin cells. The four genes \u003ca href=\"http://ww2.kqed.org/quest/2007/06/11/turning-skin-cells-into-embryonic-stem-cells/\" title=\"QUEST blog post about induced pluripotent stem cells\" target=\"_blank\">reprogrammed the skin cells to become embryonic-like stem cells\u003c/a>. \u003c/p>\n\u003cp>That led scientists to look for a way to transform one type of adult cell into another type of adult cell without the need to create stem cells at all.\u003c/p>\n\u003cp>“Yamanaka opened up the idea that adult cells weren’t permanently fixed,” said Srivastava. “That led us to ask whether or not we could convert one of these heart support cells into a heart muscle cell.” \u003c/p>\n\u003cp>Bypassing the creation of stem cells has several advantages. Though stem cells are versatile, when they’re introduced into the body they can behave as cancer cells and form tumors. \u003c/p>\n\u003cp>[ad floatright]\u003c/p>\n\u003cp>“It’s a dramatic and heady possibility that vindicates for the first time the idea that we might be able to harness truly regenerative medicine,” Marbán said. \u003c/p>\n\n","blocks":[],"excerpt":"Scientists in San Francisco have coaxed mouse hearts to repair themselves from within.The breakthrough could lead to treatments for 5 million people in the United States whose hearts were damaged after they survived heart attacks. ","status":"publish","parent":0,"modified":1457569468,"stats":{"hasAudio":false,"hasVideo":false,"hasChartOrMap":false,"iframeSrcs":[],"hasGoogleForm":false,"hasGallery":false,"hasHearkenModule":false,"hasPolis":false,"paragraphCount":25,"wordCount":1094},"headData":{"title":"Science on the SPOT: New Hope for Heart Repair | KQED","description":"Scientists in San Francisco have coaxed mouse hearts to repair themselves from within.The breakthrough could lead to treatments for 5 million people in the United States whose hearts were damaged after they survived heart attacks. ","ogTitle":"","ogDescription":"","ogImgId":"","twTitle":"","twDescription":"","twImgId":"","schema":{"@context":"http://schema.org","@type":"Article","headline":"Science on the SPOT: New Hope for Heart Repair","datePublished":"2012-04-18T17:00:06.000Z","dateModified":"2016-03-10T00:24:28.000Z","image":"https://cdn.kqed.org/wp-content/uploads/2020/02/KQED-OG-Image@1x.png"}},"disqusIdentifier":"35176 http://science.kqed.org/quest/?post_type=videos&p=35176","disqusUrl":"https://ww2.kqed.org/quest/2012/04/18/science-on-the-spot-new-hope-for-heart-repair/","disqusTitle":"Science on the SPOT: New Hope for Heart Repair","videoEmbed":"https://youtu.be/9EvI1hVq5Ys","path":"/quest/35176/science-on-the-spot-new-hope-for-heart-repair","audioTrackLength":null,"parsedContent":[{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003cp>More than 5 million people in the United States live with damaged hearts that make it difficult to walk and carry out other simple daily tasks. Pacemakers and drugs can help, but they don’t repair the heart muscle that has died as a result of a heart attack or clogged arteries.\u003c/p>\n\u003cp>Now, scientists in San Francisco say a more effective treatment might be on the way. \u003c/p>\n\u003cfigure id=\"attachment_35476\" class=\"wp-caption alignleft\" style=\"max-width: 300px\">\u003ca href=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2012/04/602B_Yu_Huang_holds_research_mouse_CU_resized.jpg\">\u003cimg src=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2012/04/602B_Yu_Huang_holds_research_mouse_CU_resized-300x169.jpg\" alt=\"Research mouse\" title=\"602B_Yu_Huang_holds_research_mouse_CU_resized\" width=\"300\" height=\"169\" class=\"size-thumbnail wp-image-35476\">\u003c/a>\u003cfigcaption class=\"wp-caption-text\">Three months after being injected with three genes, the hearts of mice that had suffered a heart attack pumped as much blood as a normal heart. Credit: Gabriela Quirós, QUEST \u003c/figcaption>\u003c/figure>\n\u003cp>The researchers from the \u003ca href=\"http://www.gladstone.ucsf.edu/gladstone/site/gweb1/\" title=\"The Gladstone Institutes\" target=\"_blank\">Gladstone Institutes\u003c/a>, affiliated with the University of California-San Francisco, reported today that using a new genetic technique, they have succeeded for the first time in repairing, from within, the hearts of mice weakened by heart attacks. \u003c/p>\n\u003cp>“There are a variety of approaches we use right now to help people who are left with damaged hearts,” said \u003ca href=\"http://www.gladstone.ucsf.edu/gladstone/site/srivastava/\" title=\"Dr. Deepak Srivastava\" target=\"_blank\">Dr. Deepak Srivastava\u003c/a>, senior author of the paper and director of cardiovascular research at the Gladstone Institutes, “but none of them actually get to the root of the problem, which is replacing that damaged heart muscle. And that’s where our focus has been.”\u003c/p>\n\u003cp>The scientists injected three genes into the hearts of research mice that had been given mild heart attacks. Within three months, the genes transformed non-beating cells in the heart into cells that looked and acted just like beating heart muscle cells. These new beating cells restored the heart’s ability to pump blood to the rest of the body. \u003c/p>\n\u003cp>\u003c/p>\u003c/div>","attributes":{"named":{},"numeric":[]}},{"type":"component","content":"","name":"ad","attributes":{"named":{"label":"fullwidth"},"numeric":["fullwidth"]}},{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003c/p>\n\u003cp>Human hearts have billions of non-beating cells, which support the beating cells by forming the heart’s structure, Srivastava said. Mice have millions of these support cells too. When a heart attack happens, the support cells rush to the site of the damage and form scar tissue, which preserves the heart’s structure, but doesn’t help it pump blood. \u003c/p>\n\u003cp>“We’ve found a way to take these support cells that should normally never become muscle, and convert them into new muscle cells that actually integrate with the rest of the heart, contribute to the force that it generates, and allow us to regenerate the heart from within the organ itself,” said Srivastava.\u003c/p>\n\u003cfigure id=\"attachment_35482\" class=\"wp-caption alignright\" style=\"max-width: 300px\">\u003ca href=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2012/04/yellow-induced-muscle-cells-with-sarcomere-structure_resized.jpg\">\u003cimg src=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2012/04/yellow-induced-muscle-cells-with-sarcomere-structure_resized-300x169.jpg\" alt=\"Mouse heart muscle cells created by Gladstone Institutes researchers.\" title=\"yellow induced muscle cells with sarcomere structure_resized\" width=\"300\" height=\"169\" class=\"size-thumbnail wp-image-35482\">\u003c/a>\u003cfigcaption class=\"wp-caption-text\">Non-beating heart cells became beating heart cells like these. Credit: Li Qian, Gladstone Institutes \u003c/figcaption>\u003c/figure>\n\u003cp>The new research appears in the April 18 online edition of the journal \u003ca href=\"http://www.nature.com/nature/index.html\" title=\"Journal Nature\" target=\"_blank\">Nature\u003c/a> and was led by \u003ca href=\"http://www.gladstone.ucsf.edu/gladstone/site/publicaffairs/content/1/736\" title=\"Li Qian wins prestigious award\" target=\"_blank\">Li Qian\u003c/a>, also from the Gladstone Institutes.\u003c/p>\n\u003cp>Heart attacks and other heart disease kill 600,000 people each year. Many more survive, yet lead diminished lives. Some 5.7 million people live with damaged hearts that pump less blood, making it difficult for them to climb a flight of stairs or walk across a parking lot. \u003c/p>\n\u003cp>During a heart attack, clots block one or several coronary arteries and cut off blood flow. By rushing patients to the operating table and unclogging their arteries with catheters and stents, doctors are able to save all but 5 percent of victims who make it to the hospital. \u003c/p>\n\u003cp>“While we’ve been doing better at saving lives, each time we save a life the patient still loses some of their muscle,” Srivastava said. “So the number of people who are left with damaged hearts is actually growing, even though the number of people who die from heart attacks is getting smaller.”\u003c/p>\n\u003cp>Treatments for humans could be six to seven years away, he added. The next step will be to test the treatment on pigs. Scientists still need to figure out if cell reprogramming is safe for humans; how to deliver the genes into the heart, and how to produce enough new beating heart cells to repair a human – rather than a mouse – heart.\u003c/p>\n\u003cp>\u003cstrong>More in our Series\u003c/strong>\u003c/p>\n\u003cul>\n\u003cli>\u003ca href=\"http://ww2.kqed.org/quest/video/childhood-obesity-kids-fight-back/\">Childhood Obesity: Kids Fight Back\u003c/a>\u003c/li>\n\u003cli>\u003ca href=\"http://ww2.kqed.org/quest/video/pump-it-up-heart-health-special-report/\">Pump It Up: Heart Health Special Report\u003c/a>\u003c/li>\n\u003cli>\u003ca href=\"http://ww2.kqed.org/quest/video/rushing-to-save-heart-attack-patients/\">Rushing to Save Heart Attack Patients\u003c/a>\u003c/li>\n\u003c/ul>\n\u003cp>Nevertheless, the research is drawing the attention of other heart researchers.\u003c/p>\n\u003cp>“It’s a major discovery and certainly suggests a new approach to treat injury that previously had been thought to be irreversible,” said \u003ca href=\"http://www.cedars-sinai.edu/Bios---Physician/H-O/Eduardo-Marban-MD.aspx\" title=\"Dr. Eduardo Marban\" target=\"_blank\">Dr. Eduardo Marbán\u003c/a>, director of the \u003ca href=\"http://www.cedars-sinai.edu/Patients/Programs-and-Services/Heart-Institute/\" title=\"Cedars-Sinai Heart Institute\" target=\"_blank\">Cedars-Sinai Heart Institute\u003c/a> in Los Angeles.\u003c/p>\n\u003cp>Marbán said it’s been “a long-held dogma” that once scar tissue has formed in the heart, it can’t change into heart muscle. This finding in mice, and recent research by Marbán’s team on a small group of human patients, challenge that belief, he said.\u003c/p>\n\u003cp>Although the cell reprogramming research doesn’t involve stem cells, the Gladstone scientists used techniques that were discovered through stem cell research. \u003c/p>\n\u003cp>The scientists said their work was inspired by the discovery in 2007 that a few genes can transform an adult skin cell into a cell with the properties of a human embryonic stem cell. Researchers have been intensely interested in \u003ca href=\"http://ww2.kqed.org/quest/video/stem-cell-gold-rush/\" title=\"QUEST TV segment about stem cell research in California\" target=\"_blank\">embryonic stem cells\u003c/a> as a possible source of treatments for diseases like Parkinson’s because they can be coaxed to turn into virtually any type of cell in the body. But because embryonic stem cells are plucked from embryos left over from fertility treatments, and require the destruction of these embryos, their study has been controversial.\u003c/p>\n\u003cp>An alternative to embryonic stem cells came with the skin cell breakthrough five years ago. Then, \u003ca href=\"http://www.gladstone.ucsf.edu/gladstone/site/yamanaka/\" title=\"Dr. Shinya Yamanaka\" target=\"_blank\">Dr. Shinya Yamanaka\u003c/a>, of the Gladstone Institutes and Kyoto University in Japan, inserted four genes that are present in embryonic stem cells into adult skin cells. The four genes \u003ca href=\"http://ww2.kqed.org/quest/2007/06/11/turning-skin-cells-into-embryonic-stem-cells/\" title=\"QUEST blog post about induced pluripotent stem cells\" target=\"_blank\">reprogrammed the skin cells to become embryonic-like stem cells\u003c/a>. \u003c/p>\n\u003cp>That led scientists to look for a way to transform one type of adult cell into another type of adult cell without the need to create stem cells at all.\u003c/p>\n\u003cp>“Yamanaka opened up the idea that adult cells weren’t permanently fixed,” said Srivastava. “That led us to ask whether or not we could convert one of these heart support cells into a heart muscle cell.” \u003c/p>\n\u003cp>Bypassing the creation of stem cells has several advantages. Though stem cells are versatile, when they’re introduced into the body they can behave as cancer cells and form tumors. \u003c/p>\n\u003cp>\u003c/p>\u003c/div>","attributes":{"named":{},"numeric":[]}},{"type":"component","content":"","name":"ad","attributes":{"named":{"label":"floatright"},"numeric":["floatright"]}},{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003c/p>\n\u003cp>“It’s a dramatic and heady possibility that vindicates for the first time the idea that we might be able to harness truly regenerative medicine,” Marbán said. \u003c/p>\n\n\u003c/div>\u003c/p>","attributes":{"named":{},"numeric":[]}}],"link":"/quest/35176/science-on-the-spot-new-hope-for-heart-repair","authors":["6186"],"series":["quest_3296"],"categories":["quest_4","quest_12","quest_3422","quest_3233"],"tags":["quest_10999","quest_793","quest_1218","quest_13201","quest_1331","quest_10997","quest_1332","quest_10998","quest_3351","quest_1783","quest_13203","quest_2349","quest_13","quest_2530","quest_2789","quest_3314","quest_3071"],"featImg":"quest_35485","label":"quest_3296"},"quest_19244":{"type":"posts","id":"quest_19244","meta":{"index":"posts_1591205157","site":"quest","id":"19244","score":null,"sort":[1308587263000]},"guestAuthors":[],"slug":"the-cloud-in-the-silver-lining","title":"The Cloud in the Silver Lining","publishDate":1308587263,"format":"standard","headTitle":"QUEST | KQED Science","labelTerm":{"site":"quest"},"content":"\u003cp>\u003cspan class=\"left\">\u003ca href=\"http://www.kqed.org/quest\">\u003cimg src=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2011/06/SilverLining.jpg\" alt=\"\">\u003c/a>\u003cem>My lower risk for Alzheimer's may be the silver lining\u003cbr>to being e2/e2 at APOE.\u003cbr>Image courtesy of \u003ca href=\"http://commons.wikimedia.org/wiki/File:Silver_Lining.JPG\">ImUnicke\u003c/a>\u003c/em>\u003c/span>\u003c/p>\n\u003cp>When last I left you in my \u003ca href=\"http://ww2.kqed.org/quest/2011/05/23/uncovering-risk-one-gene-at-a-time/\">personal genomic journey\u003c/a>, I had just discovered that I was e2/e2 at the APOE gene. I was quietly giddy* about this as it meant I was at a lower risk for getting Alzheimer’s. And even more importantly, it meant I didn’t have e4 which would have significantly increased my chances of getting this form of dementia.\u003c/p>\n\u003cp>Digging a bit deeper I found some more good news. People with e2/e2 usually have lower levels of LDL, the bad cholesterol that increases the risk for a heart attack. This is consistent with my low levels of LDL. Two good effects from one allele!\u003c/p>\n\u003cp>\u003c!--more-->\u003c/p>\n\u003cp>But there are no free lunches in genetics. For example, having two copies of the delta32 version of the CCR5 gene makes you \u003ca href=\"http://www.thetech.org/exhibits/online/ugenetics/ask.php?id=336\">pretty resistant to HIV infection\u003c/a>. But it makes you more susceptible to the West Nile Virus. Having one copy of the sickle cell version of the hemoglobin gene makes you \u003ca href=\"http://www.thetech.org/exhibits/online/ugenetics/ask.php?id=271\">resistant to malaria\u003c/a>. But your kids might end up with full blown sickle cell anemia. And so on.\u003c/p>\n\u003cp>[ad fullwidth]\u003c/p>\n\u003cp>The e2 version of the APOE gene is no different. It makes me less likely to get Alzheimer’s and, most of the time, to have a heart attack. But it means that I can end up with higher triglycerides from what I eat. This is consistent with what I have seen at the doctor’s. \u003c/p>\n\u003cp>Triglycerides are actually an independent predictor of heart attack risk. So even though my LDL is low, I need to watch my diet to keep the triglycerides down. If I am not careful, my increased triglycerides might cancel out my decreased LDL and so change my reduced heart attack risk to an increased one. \u003c/p>\n\u003cp>Being e2/e2 also puts me at risk for a relatively rare disease called \u003ca href=\"http://www.kimballgenetics.com/tests-apo_e.html\">hyperlipoproteinemia type III\u003c/a> (HLP type 3). One reason this disease is rare is because being e2/e2 is rare. For example, only around 0.4% of people of European background have this genetic combination.\u003c/p>\n\u003cp>But HLP type 3 is obviously more common for me since I am in that 0.4% group already. Still, only 2% of e2/e2 people end up with HLP type 3 so it is a low risk for me. I decided to look into it anyway.\u003c/p>\n\u003cp>This disease has various symptoms but the most worrisome ones for me are increased risk of heart attack and abnormal glucose tolerance. My fasting glucose levels are stubbornly high whenever I take my yearly blood test. Which makes me wonder if this genetic difference is affecting my glucose tolerance and I am on my way to HLP type 3.\u003c/p>\n\u003cp>Of course, lots of genetic differences are involved in establishing someone’s glucose tolerance. And the environment plays a role too. So my glucose tolerance might have nothing to do with me starting to get HLP type 3.\u003c/p>\n\u003cp>Still, I am definitely going to ask my doctor about it at my next visit. It is rare but there are specific blood tests I can ask for that can tell me if I have this condition. Who’d have thought that a lowered risk of Alzheimer’s would only be a silver lining…\u003c/p>\n\u003cp>*\u003cem>Well, more of a measured giddiness. I know this is just one of the many genes involved in Alzheimer’s but still, it was good news\u003c/em>.\u003c/p>\n\u003cp>\u003c/p>\n\u003cp> 37.3393857 -121.8949555\u003c/p>\n\n","blocks":[],"excerpt":"There are no free lunches in genetics. Having a certain version of a gene may protect you from one thing, but make you susceptible to another.","status":"publish","parent":0,"modified":1308587263,"stats":{"hasAudio":false,"hasVideo":false,"hasChartOrMap":false,"iframeSrcs":[],"hasGoogleForm":false,"hasGallery":false,"hasHearkenModule":false,"hasPolis":false,"paragraphCount":16,"wordCount":598},"headData":{"title":"The Cloud in the Silver Lining | KQED","description":"There are no free lunches in genetics. Having a certain version of a gene may protect you from one thing, but make you susceptible to another.","ogTitle":"","ogDescription":"","ogImgId":"","twTitle":"","twDescription":"","twImgId":"","schema":{"@context":"http://schema.org","@type":"Article","headline":"The Cloud in the Silver Lining","datePublished":"2011-06-20T16:27:43.000Z","dateModified":"2011-06-20T16:27:43.000Z","image":"https://cdn.kqed.org/wp-content/uploads/2020/02/KQED-OG-Image@1x.png"}},"disqusIdentifier":"19244 http://www.kqed.org/quest/blog/2011/06/20/the-cloud-in-the-silver-lining/","disqusUrl":"https://ww2.kqed.org/quest/2011/06/20/the-cloud-in-the-silver-lining/","disqusTitle":"The Cloud in the Silver Lining","path":"/quest/19244/the-cloud-in-the-silver-lining","audioTrackLength":null,"parsedContent":[{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003cp>\u003cspan class=\"left\">\u003ca href=\"http://www.kqed.org/quest\">\u003cimg src=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2011/06/SilverLining.jpg\" alt=\"\">\u003c/a>\u003cem>My lower risk for Alzheimer's may be the silver lining\u003cbr>to being e2/e2 at APOE.\u003cbr>Image courtesy of \u003ca href=\"http://commons.wikimedia.org/wiki/File:Silver_Lining.JPG\">ImUnicke\u003c/a>\u003c/em>\u003c/span>\u003c/p>\n\u003cp>When last I left you in my \u003ca href=\"http://ww2.kqed.org/quest/2011/05/23/uncovering-risk-one-gene-at-a-time/\">personal genomic journey\u003c/a>, I had just discovered that I was e2/e2 at the APOE gene. I was quietly giddy* about this as it meant I was at a lower risk for getting Alzheimer’s. And even more importantly, it meant I didn’t have e4 which would have significantly increased my chances of getting this form of dementia.\u003c/p>\n\u003cp>Digging a bit deeper I found some more good news. People with e2/e2 usually have lower levels of LDL, the bad cholesterol that increases the risk for a heart attack. This is consistent with my low levels of LDL. Two good effects from one allele!\u003c/p>\n\u003cp>\u003c!--more-->\u003c/p>\n\u003cp>But there are no free lunches in genetics. For example, having two copies of the delta32 version of the CCR5 gene makes you \u003ca href=\"http://www.thetech.org/exhibits/online/ugenetics/ask.php?id=336\">pretty resistant to HIV infection\u003c/a>. But it makes you more susceptible to the West Nile Virus. Having one copy of the sickle cell version of the hemoglobin gene makes you \u003ca href=\"http://www.thetech.org/exhibits/online/ugenetics/ask.php?id=271\">resistant to malaria\u003c/a>. But your kids might end up with full blown sickle cell anemia. And so on.\u003c/p>\n\u003cp>\u003c/p>\u003c/div>","attributes":{"named":{},"numeric":[]}},{"type":"component","content":"","name":"ad","attributes":{"named":{"label":"fullwidth"},"numeric":["fullwidth"]}},{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003c/p>\n\u003cp>The e2 version of the APOE gene is no different. It makes me less likely to get Alzheimer’s and, most of the time, to have a heart attack. But it means that I can end up with higher triglycerides from what I eat. This is consistent with what I have seen at the doctor’s. \u003c/p>\n\u003cp>Triglycerides are actually an independent predictor of heart attack risk. So even though my LDL is low, I need to watch my diet to keep the triglycerides down. If I am not careful, my increased triglycerides might cancel out my decreased LDL and so change my reduced heart attack risk to an increased one. \u003c/p>\n\u003cp>Being e2/e2 also puts me at risk for a relatively rare disease called \u003ca href=\"http://www.kimballgenetics.com/tests-apo_e.html\">hyperlipoproteinemia type III\u003c/a> (HLP type 3). One reason this disease is rare is because being e2/e2 is rare. For example, only around 0.4% of people of European background have this genetic combination.\u003c/p>\n\u003cp>But HLP type 3 is obviously more common for me since I am in that 0.4% group already. Still, only 2% of e2/e2 people end up with HLP type 3 so it is a low risk for me. I decided to look into it anyway.\u003c/p>\n\u003cp>This disease has various symptoms but the most worrisome ones for me are increased risk of heart attack and abnormal glucose tolerance. My fasting glucose levels are stubbornly high whenever I take my yearly blood test. Which makes me wonder if this genetic difference is affecting my glucose tolerance and I am on my way to HLP type 3.\u003c/p>\n\u003cp>Of course, lots of genetic differences are involved in establishing someone’s glucose tolerance. And the environment plays a role too. So my glucose tolerance might have nothing to do with me starting to get HLP type 3.\u003c/p>\n\u003cp>Still, I am definitely going to ask my doctor about it at my next visit. It is rare but there are specific blood tests I can ask for that can tell me if I have this condition. Who’d have thought that a lowered risk of Alzheimer’s would only be a silver lining…\u003c/p>\n\u003cp>*\u003cem>Well, more of a measured giddiness. I know this is just one of the many genes involved in Alzheimer’s but still, it was good news\u003c/em>.\u003c/p>\n\u003cp>\u003c/p>\n\u003cp> 37.3393857 -121.8949555\u003c/p>\n\n\u003c/div>\u003c/p>","attributes":{"named":{},"numeric":[]}}],"link":"/quest/19244/the-cloud-in-the-silver-lining","authors":["6177"],"categories":["quest_4"],"tags":["quest_134","quest_135","quest_3458","quest_3546","quest_3553","quest_3555","quest_1192","quest_1197","quest_1332","quest_3610","quest_2162","quest_3804"],"featImg":"quest_15236","label":"quest"},"quest_12346":{"type":"posts","id":"quest_12346","meta":{"index":"posts_1591205157","site":"quest","id":"12346","score":null,"sort":[1298048441000]},"guestAuthors":[],"slug":"scientists-understand-heart-disease-better-still-give-bad-advice","title":"Scientists Understand Heart Disease Better, Still Give Bad Advice","publishDate":1298048441,"format":"standard","headTitle":"QUEST | KQED Science","labelTerm":{"site":"quest"},"content":"\u003cp>\u003cspan class=\"left\">\u003cimg src=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2011/02/fastfood12.jpg\" alt=\"\">\u003cem>Calling fast food \"high fat\" is true, but misleading. Image courtesy of \u003ca href=\"http://www.flickr.com/photos/avlxyz/3861444749/\">avlxyz\u003c/a>.\u003c/em>\u003c/span>\u003c/p>\n\u003cp>\u003ca href=\"http://ajpheart.physiology.org/content/early/2010/12/10/ajpheart.01036.2010.abstract\">New research\u003c/a> from UC Davis sheds light on how triglycerides induce atherosclerosis—the hardening of artery walls that causes heart disease—particularly in individuals with abdominal obesity. Unfortunately, however, the researchers credit the fat in the fast food meal they used to induce the triglyceride spike, while letting the more likely culprit, orange juice, completely off the hook.\u003c/p>\n\u003cp>In the study, researchers fed a fast food meal (two breakfast sandwiches, hash browns and orange juice, as noted in the \u003ca href=\"http://www.news.ucdavis.edu/search/news_detail.lasso?id=9767\">press release\u003c/a>) to people with either normal or elevated blood triglycerides. Triglycerides correlate strongly with risk of heart disease and are \u003ca href=\"http://www.ncbi.nlm.nih.gov/pubmed/19436658\">a better predictor of cardiovascular risk than total or LDL cholesterol\u003c/a>.\u003c/p>\n\u003cp>\u003c!--more-->\u003c/p>\n\u003cp>After eating the horrible meal, triglycerides rose and LDL cholesterol was transported into cells in the artery wall, a process that leads to artery hardening and heart disease. This effect was worsened in the presence of cytokines, which are known to cause inflammation and correlate with a larger waist size.\u003c/p>\n\u003cp>[ad fullwidth]\u003c/p>\n\u003cp>The implication is that poor diet choices become more dangerous as a person's metabolic health declines, making good nutrition an even greater priority for people with abdominal obesity.\u003c/p>\n\u003cp>“The new study shows that eating a common fast food meal can affect inflammatory responses in the blood vessels,\" said the lead researcher, Anthony Passerini, and the effect seems to be worse in those with chronic inflammation and larger waists.\u003c/p>\n\u003cp>But why do they extrapolate and claim that this problem is caused by dietary fat?\u003c/p>\n\u003cp>The authors describe the fast food meal as “high-fat”, but neglect that it is also high in processed carbohydrates (two buns and hash browns) and fructose, the fruit sugar present in orange juice. Fructose is converted to triglycerides in the liver and is the \u003ca href=\"http://www.ajcn.org/content/20/2/131.long\">most effective way to increase triglyceride levels\u003c/a>.\u003c/p>\n\u003cp>Not only is fructose from the orange juice the most likely cause of the triglyceride effect, but it is particularly unlikely the fat had an impact. \u003ca href=\"http://www.ncbi.nlm.nih.gov/pubmed/5916038\">High-fat, low-carbohydrate diets have been used to \u003cem>treat\u003c/em> high triglycerides since the 1960s\u003c/a>, even at levels as high as 65% of calories from fat. In the current study the fat in the fast food meal represented only 47% of calories.\u003c/p>\n\u003cp>Though the fast food meal used by the researchers undoubtedly matches the “typical western diet,” it is unlikely that the fat content is responsible for elevating triglycerides and the risk of heart disease that comes with them.\u003c/p>\n\u003cp>A better message for people worried about triglycerides: watch your sugar.\u003c/p>\n\u003cp>\u003c/p>\n\u003cp> 38.5397702 -121.7554965\u003c/p>\n\n","blocks":[],"excerpt":"High-fat, low-carbohydrate diets have been used to treat high triglycerides since the 1960s.","status":"publish","parent":0,"modified":1371061507,"stats":{"hasAudio":false,"hasVideo":false,"hasChartOrMap":false,"iframeSrcs":[],"hasGoogleForm":false,"hasGallery":false,"hasHearkenModule":false,"hasPolis":false,"paragraphCount":15,"wordCount":439},"headData":{"title":"Scientists Understand Heart Disease Better, Still Give Bad Advice | KQED","description":"High-fat, low-carbohydrate diets have been used to treat high triglycerides since the 1960s.","ogTitle":"","ogDescription":"","ogImgId":"","twTitle":"","twDescription":"","twImgId":"","schema":{"@context":"http://schema.org","@type":"Article","headline":"Scientists Understand Heart Disease Better, Still Give Bad Advice","datePublished":"2011-02-18T17:00:41.000Z","dateModified":"2013-06-12T18:25:07.000Z","image":"https://cdn.kqed.org/wp-content/uploads/2020/02/KQED-OG-Image@1x.png"}},"disqusIdentifier":"12346 http://www.kqed.org/quest/blog/?p=12346","disqusUrl":"https://ww2.kqed.org/quest/2011/02/18/scientists-understand-heart-disease-better-still-give-bad-advice/","disqusTitle":"Scientists Understand Heart Disease Better, Still Give Bad Advice","path":"/quest/12346/scientists-understand-heart-disease-better-still-give-bad-advice","audioTrackLength":null,"parsedContent":[{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003cp>\u003cspan class=\"left\">\u003cimg src=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2011/02/fastfood12.jpg\" alt=\"\">\u003cem>Calling fast food \"high fat\" is true, but misleading. Image courtesy of \u003ca href=\"http://www.flickr.com/photos/avlxyz/3861444749/\">avlxyz\u003c/a>.\u003c/em>\u003c/span>\u003c/p>\n\u003cp>\u003ca href=\"http://ajpheart.physiology.org/content/early/2010/12/10/ajpheart.01036.2010.abstract\">New research\u003c/a> from UC Davis sheds light on how triglycerides induce atherosclerosis—the hardening of artery walls that causes heart disease—particularly in individuals with abdominal obesity. Unfortunately, however, the researchers credit the fat in the fast food meal they used to induce the triglyceride spike, while letting the more likely culprit, orange juice, completely off the hook.\u003c/p>\n\u003cp>In the study, researchers fed a fast food meal (two breakfast sandwiches, hash browns and orange juice, as noted in the \u003ca href=\"http://www.news.ucdavis.edu/search/news_detail.lasso?id=9767\">press release\u003c/a>) to people with either normal or elevated blood triglycerides. Triglycerides correlate strongly with risk of heart disease and are \u003ca href=\"http://www.ncbi.nlm.nih.gov/pubmed/19436658\">a better predictor of cardiovascular risk than total or LDL cholesterol\u003c/a>.\u003c/p>\n\u003cp>\u003c!--more-->\u003c/p>\n\u003cp>After eating the horrible meal, triglycerides rose and LDL cholesterol was transported into cells in the artery wall, a process that leads to artery hardening and heart disease. This effect was worsened in the presence of cytokines, which are known to cause inflammation and correlate with a larger waist size.\u003c/p>\n\u003cp>\u003c/p>\u003c/div>","attributes":{"named":{},"numeric":[]}},{"type":"component","content":"","name":"ad","attributes":{"named":{"label":"fullwidth"},"numeric":["fullwidth"]}},{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003c/p>\n\u003cp>The implication is that poor diet choices become more dangerous as a person's metabolic health declines, making good nutrition an even greater priority for people with abdominal obesity.\u003c/p>\n\u003cp>“The new study shows that eating a common fast food meal can affect inflammatory responses in the blood vessels,\" said the lead researcher, Anthony Passerini, and the effect seems to be worse in those with chronic inflammation and larger waists.\u003c/p>\n\u003cp>But why do they extrapolate and claim that this problem is caused by dietary fat?\u003c/p>\n\u003cp>The authors describe the fast food meal as “high-fat”, but neglect that it is also high in processed carbohydrates (two buns and hash browns) and fructose, the fruit sugar present in orange juice. Fructose is converted to triglycerides in the liver and is the \u003ca href=\"http://www.ajcn.org/content/20/2/131.long\">most effective way to increase triglyceride levels\u003c/a>.\u003c/p>\n\u003cp>Not only is fructose from the orange juice the most likely cause of the triglyceride effect, but it is particularly unlikely the fat had an impact. \u003ca href=\"http://www.ncbi.nlm.nih.gov/pubmed/5916038\">High-fat, low-carbohydrate diets have been used to \u003cem>treat\u003c/em> high triglycerides since the 1960s\u003c/a>, even at levels as high as 65% of calories from fat. In the current study the fat in the fast food meal represented only 47% of calories.\u003c/p>\n\u003cp>Though the fast food meal used by the researchers undoubtedly matches the “typical western diet,” it is unlikely that the fat content is responsible for elevating triglycerides and the risk of heart disease that comes with them.\u003c/p>\n\u003cp>A better message for people worried about triglycerides: watch your sugar.\u003c/p>\n\u003cp>\u003c/p>\n\u003cp> 38.5397702 -121.7554965\u003c/p>\n\n\u003c/div>\u003c/p>","attributes":{"named":{},"numeric":[]}}],"link":"/quest/12346/scientists-understand-heart-disease-better-still-give-bad-advice","authors":["10218"],"categories":["quest_12"],"tags":["quest_3441","quest_3467","quest_3498","quest_3543","quest_1077","quest_3583","quest_1332","quest_2822","quest_3804"],"featImg":"quest_12370","label":"quest"},"quest_11758":{"type":"posts","id":"quest_11758","meta":{"index":"posts_1591205157","site":"quest","id":"11758","score":null,"sort":[1295631042000]},"guestAuthors":[],"slug":"sugar-to-blame-for-increased-heart-disease-risk-in-teens","title":"Sugar To Blame For Increased Heart Disease Risk In Teens","publishDate":1295631042,"format":"standard","headTitle":"QUEST | KQED Science","labelTerm":{"site":"quest"},"content":"\u003cp>\u003cspan class=\"left\">\u003cimg src=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2011/01/lollipop1.jpg\" alt=\"\">\u003cem>Sugar consumption among adolescents has nearly doubled since the 1970s. Image courtesy of \u003ca href=\"http://www.flickr.com/photos/e3000/3636051253/\">e³°°°\u003c/a>.\u003c/em>\u003c/span>\u003c/p>\n\u003cp>Early signs of heart disease are reaching kids at younger ages every year. A new study published by the American Heart Association's journal, \u003cem>\u003ca href=\"http://circ.ahajournals.org/cgi/content/abstract/CIRCULATIONAHA.110.972166v1\">Circulation\u003c/a>\u003c/em>, suggests that added sugars may be the reason.\u003c/p>\n\u003cp>The study examined data from almost 2,500 adolescents ages 12 to 18 from the National Health and Nutrition Examination Survey (NHANES). Dietary questionnaires were used to divide the participants into 6 groups based on the percentage of calories from added sugar.\u003c/p>\n\u003cp>\u003c!--more-->\u003c/p>\n\u003cp>There were no differences in the amount of added sugar consumed among any demographic factors including age, gender, ethnicity, income or education level. Likewise, there were no differences between the amount of added sugars and physical activity or total calories. Higher sugar intake was therefore associated with less protein and, notably, less fat consumption.\u003c/p>\n\u003cp>[ad fullwidth]\u003c/p>\n\u003cp>The more sugar participants ate, the worse their blood lipid profiles. Healthy HDL cholesterol was significantly lower in those who ate the most sugar compared to those who ate the least. However, triglycerides and LDL cholesterol were both approximately 10% higher in those who consumed the most sugar.\u003c/p>\n\u003cp>Lipid profiles did not correlate with body weight, meaning high sugar intake was just as unhealthy for the slim kids as for the overweight kids. However, body weight did correlate with measures of insulin resistance, and in these cases high sugar intake was more dangerous for the overweight participants.\u003c/p>\n\u003cp>In 1986, the Sugar Task Force of the US Food and Drug Administration estimated that from 1977-1978 average sugar consumption among adolescents was between 62-84 g per day. In the current study, which measured data from 1999-2004, daily sugar intake increased to 119 g. Interestingly, the 1986 Sugar Task Force had concluded that sugar did not have an effect on heart disease risk.\u003c/p>\n\u003cp>UCSF pediatric endocrinologist Dr. Robert Lustig told \u003ca href=\"http://sanfrancisco.cbslocal.com/2011/01/12/healthwatch-sugars-may-increase-heart-disease-risk-in-teens/%20that%20in%20his%20clinic\">CBS San Francisco\u003c/a>, “Children are already showing signs of cardiovascular disease even during puberty.”\u003c/p>\n\u003cp>Lustig went on to say that “if nothing is done then we can expect an entire generation of cardiac cripples by the time they're 40.”\u003c/p>\n\u003cp>\u003c/p>\n\u003cp> 37.76355 -122.458\u003c/p>\n\n","blocks":[],"excerpt":"Sugar consumption among adolescents has nearly doubled since the 1970s.","status":"publish","parent":0,"modified":1295631042,"stats":{"hasAudio":false,"hasVideo":false,"hasChartOrMap":false,"iframeSrcs":[],"hasGoogleForm":false,"hasGallery":false,"hasHearkenModule":false,"hasPolis":false,"paragraphCount":13,"wordCount":367},"headData":{"title":"Sugar To Blame For Increased Heart Disease Risk In Teens | KQED","description":"Sugar consumption among adolescents has nearly doubled since the 1970s.","ogTitle":"","ogDescription":"","ogImgId":"","twTitle":"","twDescription":"","twImgId":"","schema":{"@context":"http://schema.org","@type":"Article","headline":"Sugar To Blame For Increased Heart Disease Risk In Teens","datePublished":"2011-01-21T17:30:42.000Z","dateModified":"2011-01-21T17:30:42.000Z","image":"https://cdn.kqed.org/wp-content/uploads/2020/02/KQED-OG-Image@1x.png"}},"disqusIdentifier":"11758 http://www.kqed.org/quest/blog/?p=11758","disqusUrl":"https://ww2.kqed.org/quest/2011/01/21/sugar-to-blame-for-increased-heart-disease-risk-in-teens/","disqusTitle":"Sugar To Blame For Increased Heart Disease Risk In Teens","path":"/quest/11758/sugar-to-blame-for-increased-heart-disease-risk-in-teens","audioTrackLength":null,"parsedContent":[{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003cp>\u003cspan class=\"left\">\u003cimg src=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2011/01/lollipop1.jpg\" alt=\"\">\u003cem>Sugar consumption among adolescents has nearly doubled since the 1970s. Image courtesy of \u003ca href=\"http://www.flickr.com/photos/e3000/3636051253/\">e³°°°\u003c/a>.\u003c/em>\u003c/span>\u003c/p>\n\u003cp>Early signs of heart disease are reaching kids at younger ages every year. A new study published by the American Heart Association's journal, \u003cem>\u003ca href=\"http://circ.ahajournals.org/cgi/content/abstract/CIRCULATIONAHA.110.972166v1\">Circulation\u003c/a>\u003c/em>, suggests that added sugars may be the reason.\u003c/p>\n\u003cp>The study examined data from almost 2,500 adolescents ages 12 to 18 from the National Health and Nutrition Examination Survey (NHANES). Dietary questionnaires were used to divide the participants into 6 groups based on the percentage of calories from added sugar.\u003c/p>\n\u003cp>\u003c!--more-->\u003c/p>\n\u003cp>There were no differences in the amount of added sugar consumed among any demographic factors including age, gender, ethnicity, income or education level. Likewise, there were no differences between the amount of added sugars and physical activity or total calories. Higher sugar intake was therefore associated with less protein and, notably, less fat consumption.\u003c/p>\n\u003cp>\u003c/p>\u003c/div>","attributes":{"named":{},"numeric":[]}},{"type":"component","content":"","name":"ad","attributes":{"named":{"label":"fullwidth"},"numeric":["fullwidth"]}},{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003c/p>\n\u003cp>The more sugar participants ate, the worse their blood lipid profiles. Healthy HDL cholesterol was significantly lower in those who ate the most sugar compared to those who ate the least. However, triglycerides and LDL cholesterol were both approximately 10% higher in those who consumed the most sugar.\u003c/p>\n\u003cp>Lipid profiles did not correlate with body weight, meaning high sugar intake was just as unhealthy for the slim kids as for the overweight kids. However, body weight did correlate with measures of insulin resistance, and in these cases high sugar intake was more dangerous for the overweight participants.\u003c/p>\n\u003cp>In 1986, the Sugar Task Force of the US Food and Drug Administration estimated that from 1977-1978 average sugar consumption among adolescents was between 62-84 g per day. In the current study, which measured data from 1999-2004, daily sugar intake increased to 119 g. Interestingly, the 1986 Sugar Task Force had concluded that sugar did not have an effect on heart disease risk.\u003c/p>\n\u003cp>UCSF pediatric endocrinologist Dr. Robert Lustig told \u003ca href=\"http://sanfrancisco.cbslocal.com/2011/01/12/healthwatch-sugars-may-increase-heart-disease-risk-in-teens/%20that%20in%20his%20clinic\">CBS San Francisco\u003c/a>, “Children are already showing signs of cardiovascular disease even during puberty.”\u003c/p>\n\u003cp>Lustig went on to say that “if nothing is done then we can expect an entire generation of cardiac cripples by the time they're 40.”\u003c/p>\n\u003cp>\u003c/p>\n\u003cp> 37.76355 -122.458\u003c/p>\n\n\u003c/div>\u003c/p>","attributes":{"named":{},"numeric":[]}}],"link":"/quest/11758/sugar-to-blame-for-increased-heart-disease-risk-in-teens","authors":["10218"],"categories":["quest_12"],"tags":["quest_139","quest_591","quest_830","quest_1332","quest_1925","quest_2822","quest_2887"],"featImg":"quest_11760","label":"quest"},"quest_8124":{"type":"posts","id":"quest_8124","meta":{"index":"posts_1591205157","site":"quest","id":"8124","score":null,"sort":[1284156010000]},"guestAuthors":[],"slug":"reporters-notes-california-takes-the-lead-on-stem-cell-research","title":"Reporter's Notes: California Takes the Lead on Stem Cell Research","publishDate":1284156010,"format":"audio","headTitle":"QUEST | KQED Science","labelTerm":{"site":"quest"},"content":"\u003cp>\u003cspan class=\"left\">\u003ca href=\"http://ww2.kqed.org/quest/audio/california-takes-the-lead-on-stem-cell-research\">\u003cimg src=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2010/09/4-46StemCell_300.jpg\" alt=\"\">\u003c/a>\u003cem> Image courtesy of Jeff Miller, University of Wisconsin-Madison.\u003c/em>\u003c/span>\u003c/p>\n\u003cp>Deepak Srivastava – profiled in \u003ca href=\"http://ww2.kqed.org/quest/audio/california-takes-the-lead-on-stem-cell-research\">this week's radio story\u003c/a> – is no stranger to \u003ca href=\"http://www.kqed.org/quest/television/view/326\" target=\"_top\">QUEST\u003c/a>, or to \u003ca href=\"http://www.kqed.org/news/\" target=\"_top\">KQED News\u003c/a>. Just last month, \u003ca href=\"http://ww2.kqed.org/quest/2010/08/05/new-approach-to-creating-heart-cells-could-make-transplantation-unnecessary/\" target=\"_top\">Srivastava made headlines\u003c/a> when he announced that his lab had for the first time directly created beating heart cells from adult cells, without having to go through the stem cell stage.\u003cbr>\n\u003c!--more-->\u003c/p>\n\u003cp>But when I interviewed Srivastava for this story, I wanted to hear as well about his work with a type of stem cell called \u003ca href=\"http://www.nytimes.com/2007/12/11/science/11prof.html?_r=1\" target=\"_top\">induced pluripotent cells\u003c/a>. These are adult cells that have been coaxed into becoming like embryonic stem cells. Just like embryonic stem cells, these transformed cells are \"pluripotent,\" meaning that they have the ability to develop into any other kind of cell.\u003cbr>\nIf researchers like Srivastava can do pioneering work without requiring human embryonic stem cells, I wondered, then what to make of the \u003ca href=\"http://www.huffingtonpost.com/eli-y-adashi/the-halting-of-stem-cell-_b_711616.html\" target=\"_top\">recent ruling by US district court Judge Royce Lamberth?\u003c/a>\u003c/p>\n\u003cp>From a scientific standpoint, at least, was the debate over the \u003ca href=\"http://en.wikipedia.org/wiki/Dickey-Wicker_Amendment\" target=\"_top\">Dickey-Wicker Amendment\u003c/a> a moot point?\u003c/p>\n\u003cp>And finally, if human embryonic stem cells are no longer necessary, where does that leave \u003ca href=\"http://www.cirm.ca.gov/\" target=\"_top\">The California Institute For Regenerative Medicine\u003c/a>, \u003ca href=\"http://en.wikipedia.org/wiki/California_Proposition_71_(2004)\" target=\"_top\">the taxpayer-funded\u003c/a>, \u003ca href=\"http://www.cirm.ca.gov/GrantsSummary\" target=\"_top\">$3 billion\u003c/a> foundation created specifically to ensure that human embryonic stem cell research continues, regardless of federal support?\u003c/p>\n\u003cp>[ad fullwidth]\u003c/p>\n\u003cp>Here's how The Institute – which funds \u003ca href=\"http://www.cirm.ca.gov/Grant_overview_charts\" target=\"_top\">research on induced pluripotent stem cells and other cells\u003c/a>, as well as embryonic stem cells, \u003ca href=\"http://www.cirm.ca.gov/StemCellBasics_Questions#6\" target=\"_top\">answers that question\u003c/a>.\u003c/p>\n\u003cp>And here's \u003ca href=\"http://www.isscr.org/ScienceStatementEndorsers.cfm\" target=\"_top\">a letter\u003c/a>, signed by 834 scientists in defense of continued support of research on both types of cells. An excerpt:\u003c/p>\n\u003cp>\"The basic tools for these discoveries will include the “gold standard” embryonic stem cells that remain the benchmark for assessment of pluripotency, or the ability to develop into all the fully functional cells of the body.\"\u003c/p>\n\u003cp>And that's exactly the term Srivastava used: \"gold standard.\" Adult cells that can be transformed into embryonic stem cell-like cells may well someday free researchers from the political roller coaster of embryonic stem cell support, he said. But first, scientists need to figure out exactly how well they work. And without human embryonic stem cells, there's just nothing to compare them to.\u003c/p>\n\u003cp>\u003cobject width=\"640\" height=\"385\">\u003cparam name=\"movie\" value=\"http://www.youtube.com/v/tOdyaiWr0oo&color1=0xb1b1b1&color2=0xd0d0d0&hl=en_US&feature=player_embedded&fs=1\">\u003cparam name=\"allowFullScreen\" value=\"true\">\u003cparam name=\"allowScriptAccess\" value=\"always\">\u003cembed src=\"http://www.youtube.com/v/tOdyaiWr0oo&color1=0xb1b1b1&color2=0xd0d0d0&hl=en_US&feature=player_embedded&fs=1\" type=\"application/x-shockwave-flash\" allowfullscreen=\"true\" allowscriptaccess=\"always\" width=\"640\" height=\"385\">\u003c/embed>\u003c/object>\u003c/p>\n\u003cp>\u003cem>Video of beating heart cell created from adult cells - Courtesy of the Gladstone Institute of Cardiovascular Disease\u003c/em>\u003c/p>\n\u003cp>\u003cspan class=\"left\">\u003ca href=\"http://ww2.kqed.org/quest/audio/california-takes-the-lead-on-stem-cell-research\">\u003cimg src=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2010/09/radio_icon_light.gif\" alt=\"\">\u003c/a>\u003c/span>\u003ca href=\"http://ww2.kqed.org/quest/audio/california-takes-the-lead-on-stem-cell-research\">Listen to the California Takes the Lead on Stem Cell Research \u003c/a> radio report online.\u003c/p>\n\u003cp>\u003c/p>\n\u003cp> 37.7677229 -122.3942944\u003c/p>\n\n","blocks":[],"excerpt":"Deepak Srivastava – profiled in this week's radio story – is no stranger to QUEST. Just last month, Srivastava made headlines when he announced that his lab had successfully created beating heart cells from adult cells.","status":"publish","parent":0,"modified":1371076084,"stats":{"hasAudio":false,"hasVideo":false,"hasChartOrMap":false,"iframeSrcs":[],"hasGoogleForm":false,"hasGallery":false,"hasHearkenModule":false,"hasPolis":false,"paragraphCount":15,"wordCount":419},"headData":{"title":"Reporter's Notes: California Takes the Lead on Stem Cell Research | KQED","description":"Deepak Srivastava – profiled in this week's radio story – is no stranger to QUEST. Just last month, Srivastava made headlines when he announced that his lab had successfully created beating heart cells from adult cells.","ogTitle":"","ogDescription":"","ogImgId":"","twTitle":"","twDescription":"","twImgId":"","schema":{"@context":"http://schema.org","@type":"Article","headline":"Reporter's Notes: California Takes the Lead on Stem Cell Research","datePublished":"2010-09-10T22:00:10.000Z","dateModified":"2013-06-12T22:28:04.000Z","image":"https://cdn.kqed.org/wp-content/uploads/2020/02/KQED-OG-Image@1x.png"}},"disqusIdentifier":"8124 http://science.kqed.org/quest/2010/09/10/reporters-notes-california-takes-the-lead-on-stem-cell-research/","disqusUrl":"https://ww2.kqed.org/quest/2010/09/10/reporters-notes-california-takes-the-lead-on-stem-cell-research/","disqusTitle":"Reporter's Notes: California Takes the Lead on Stem Cell Research","path":"/quest/8124/reporters-notes-california-takes-the-lead-on-stem-cell-research","audioTrackLength":null,"parsedContent":[{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003cp>\u003cspan class=\"left\">\u003ca href=\"http://ww2.kqed.org/quest/audio/california-takes-the-lead-on-stem-cell-research\">\u003cimg src=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2010/09/4-46StemCell_300.jpg\" alt=\"\">\u003c/a>\u003cem> Image courtesy of Jeff Miller, University of Wisconsin-Madison.\u003c/em>\u003c/span>\u003c/p>\n\u003cp>Deepak Srivastava – profiled in \u003ca href=\"http://ww2.kqed.org/quest/audio/california-takes-the-lead-on-stem-cell-research\">this week's radio story\u003c/a> – is no stranger to \u003ca href=\"http://www.kqed.org/quest/television/view/326\" target=\"_top\">QUEST\u003c/a>, or to \u003ca href=\"http://www.kqed.org/news/\" target=\"_top\">KQED News\u003c/a>. Just last month, \u003ca href=\"http://ww2.kqed.org/quest/2010/08/05/new-approach-to-creating-heart-cells-could-make-transplantation-unnecessary/\" target=\"_top\">Srivastava made headlines\u003c/a> when he announced that his lab had for the first time directly created beating heart cells from adult cells, without having to go through the stem cell stage.\u003cbr>\n\u003c!--more-->\u003c/p>\n\u003cp>But when I interviewed Srivastava for this story, I wanted to hear as well about his work with a type of stem cell called \u003ca href=\"http://www.nytimes.com/2007/12/11/science/11prof.html?_r=1\" target=\"_top\">induced pluripotent cells\u003c/a>. These are adult cells that have been coaxed into becoming like embryonic stem cells. Just like embryonic stem cells, these transformed cells are \"pluripotent,\" meaning that they have the ability to develop into any other kind of cell.\u003cbr>\nIf researchers like Srivastava can do pioneering work without requiring human embryonic stem cells, I wondered, then what to make of the \u003ca href=\"http://www.huffingtonpost.com/eli-y-adashi/the-halting-of-stem-cell-_b_711616.html\" target=\"_top\">recent ruling by US district court Judge Royce Lamberth?\u003c/a>\u003c/p>\n\u003cp>From a scientific standpoint, at least, was the debate over the \u003ca href=\"http://en.wikipedia.org/wiki/Dickey-Wicker_Amendment\" target=\"_top\">Dickey-Wicker Amendment\u003c/a> a moot point?\u003c/p>\n\u003cp>And finally, if human embryonic stem cells are no longer necessary, where does that leave \u003ca href=\"http://www.cirm.ca.gov/\" target=\"_top\">The California Institute For Regenerative Medicine\u003c/a>, \u003ca href=\"http://en.wikipedia.org/wiki/California_Proposition_71_(2004)\" target=\"_top\">the taxpayer-funded\u003c/a>, \u003ca href=\"http://www.cirm.ca.gov/GrantsSummary\" target=\"_top\">$3 billion\u003c/a> foundation created specifically to ensure that human embryonic stem cell research continues, regardless of federal support?\u003c/p>\n\u003cp>\u003c/p>\u003c/div>","attributes":{"named":{},"numeric":[]}},{"type":"component","content":"","name":"ad","attributes":{"named":{"label":"fullwidth"},"numeric":["fullwidth"]}},{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003c/p>\n\u003cp>Here's how The Institute – which funds \u003ca href=\"http://www.cirm.ca.gov/Grant_overview_charts\" target=\"_top\">research on induced pluripotent stem cells and other cells\u003c/a>, as well as embryonic stem cells, \u003ca href=\"http://www.cirm.ca.gov/StemCellBasics_Questions#6\" target=\"_top\">answers that question\u003c/a>.\u003c/p>\n\u003cp>And here's \u003ca href=\"http://www.isscr.org/ScienceStatementEndorsers.cfm\" target=\"_top\">a letter\u003c/a>, signed by 834 scientists in defense of continued support of research on both types of cells. An excerpt:\u003c/p>\n\u003cp>\"The basic tools for these discoveries will include the “gold standard” embryonic stem cells that remain the benchmark for assessment of pluripotency, or the ability to develop into all the fully functional cells of the body.\"\u003c/p>\n\u003cp>And that's exactly the term Srivastava used: \"gold standard.\" Adult cells that can be transformed into embryonic stem cell-like cells may well someday free researchers from the political roller coaster of embryonic stem cell support, he said. But first, scientists need to figure out exactly how well they work. And without human embryonic stem cells, there's just nothing to compare them to.\u003c/p>\n\u003cp>\u003cobject width=\"640\" height=\"385\">\u003cparam name=\"movie\" value=\"http://www.youtube.com/v/tOdyaiWr0oo&color1=0xb1b1b1&color2=0xd0d0d0&hl=en_US&feature=player_embedded&fs=1\">\u003cparam name=\"allowFullScreen\" value=\"true\">\u003cparam name=\"allowScriptAccess\" value=\"always\">\u003cembed src=\"http://www.youtube.com/v/tOdyaiWr0oo&color1=0xb1b1b1&color2=0xd0d0d0&hl=en_US&feature=player_embedded&fs=1\" type=\"application/x-shockwave-flash\" allowfullscreen=\"true\" allowscriptaccess=\"always\" width=\"640\" height=\"385\">\u003c/embed>\u003c/object>\u003c/p>\n\u003cp>\u003cem>Video of beating heart cell created from adult cells - Courtesy of the Gladstone Institute of Cardiovascular Disease\u003c/em>\u003c/p>\n\u003cp>\u003cspan class=\"left\">\u003ca href=\"http://ww2.kqed.org/quest/audio/california-takes-the-lead-on-stem-cell-research\">\u003cimg src=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2010/09/radio_icon_light.gif\" alt=\"\">\u003c/a>\u003c/span>\u003ca href=\"http://ww2.kqed.org/quest/audio/california-takes-the-lead-on-stem-cell-research\">Listen to the California Takes the Lead on Stem Cell Research \u003c/a> radio report online.\u003c/p>\n\u003cp>\u003c/p>\n\u003cp> 37.7677229 -122.3942944\u003c/p>\n\n\u003c/div>\u003c/p>","attributes":{"named":{},"numeric":[]}}],"link":"/quest/8124/reporters-notes-california-takes-the-lead-on-stem-cell-research","authors":["210"],"categories":["quest_12"],"tags":["quest_252","quest_313","quest_449","quest_606","quest_793","quest_1203","quest_1218","quest_1332","quest_1360","quest_1408","quest_1498","quest_1547","quest_2459"],"label":"quest"}},"programsReducer":{"possible":{"id":"possible","title":"Possible","info":"Possible is hosted by entrepreneur Reid Hoffman and writer Aria Finger. Together in Possible, Hoffman and Finger lead enlightening discussions about building a brighter collective future. The show features interviews with visionary guests like Trevor Noah, Sam Altman and Janette Sadik-Khan. Possible paints an optimistic portrait of the world we can create through science, policy, business, art and our shared humanity. It asks: What if everything goes right for once? How can we get there? Each episode also includes a short fiction story generated by advanced AI GPT-4, serving as a thought-provoking springboard to speculate how humanity could leverage technology for good.","airtime":"SUN 2pm","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/Possible-Podcast-Tile-360x360-1.jpg","officialWebsiteLink":"https://www.possible.fm/","meta":{"site":"news","source":"Possible"},"link":"/radio/program/possible","subscribe":{"apple":"https://podcasts.apple.com/us/podcast/possible/id1677184070","spotify":"https://open.spotify.com/show/730YpdUSNlMyPQwNnyjp4k"}},"1a":{"id":"1a","title":"1A","info":"1A is home to the national conversation. 1A brings on great guests and frames the best debate in ways that make you think, share and engage.","airtime":"MON-THU 11pm-12am","imageSrc":"https://ww2.kqed.org/radio/wp-content/uploads/sites/50/2018/04/1a.jpg","officialWebsiteLink":"https://the1a.org/","meta":{"site":"news","source":"npr"},"link":"/radio/program/1a","subscribe":{"npr":"https://rpb3r.app.goo.gl/RBrW","apple":"https://itunes.apple.com/WebObjects/MZStore.woa/wa/viewPodcast?s=143441&mt=2&id=1188724250&at=11l79Y&ct=nprdirectory","tuneIn":"https://tunein.com/radio/1A-p947376/","rss":"https://feeds.npr.org/510316/podcast.xml"}},"all-things-considered":{"id":"all-things-considered","title":"All Things Considered","info":"Every weekday, \u003cem>All Things Considered\u003c/em> hosts Robert Siegel, Audie Cornish, Ari Shapiro, and Kelly McEvers present the program's trademark mix of news, interviews, commentaries, reviews, and offbeat features. Michel Martin hosts on the weekends.","airtime":"MON-FRI 1pm-2pm, 4:30pm-6:30pm\u003cbr />SAT-SUN 5pm-6pm","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/All-Things-Considered-Podcast-Tile-360x360-1.jpg","officialWebsiteLink":"https://www.npr.org/programs/all-things-considered/","meta":{"site":"news","source":"npr"},"link":"/radio/program/all-things-considered"},"american-suburb-podcast":{"id":"american-suburb-podcast","title":"American Suburb: The Podcast","tagline":"The flip side of gentrification, told through one town","info":"Gentrification is changing cities across America, forcing people from neighborhoods they have long called home. Call them the displaced. Now those priced out of the Bay Area are looking for a better life in an unlikely place. American Suburb follows this migration to one California town along the Delta, 45 miles from San Francisco. But is this once sleepy suburb ready for them?","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/American-Suburb-Podcast-Tile-703x703-1.jpg","officialWebsiteLink":"/news/series/american-suburb-podcast","meta":{"site":"news","source":"kqed","order":"13"},"link":"/news/series/american-suburb-podcast/","subscribe":{"npr":"https://rpb3r.app.goo.gl/RBrW","apple":"https://itunes.apple.com/WebObjects/MZStore.woa/wa/viewPodcast?mt=2&id=1287748328","tuneIn":"https://tunein.com/radio/American-Suburb-p1086805/","rss":"https://ww2.kqed.org/news/series/american-suburb-podcast/feed/podcast","google":"https://podcasts.google.com/feed/aHR0cHM6Ly9mZWVkcy5tZWdhcGhvbmUuZm0vS1FJTkMzMDExODgxNjA5"}},"baycurious":{"id":"baycurious","title":"Bay Curious","tagline":"Exploring the Bay Area, one question at a time","info":"KQED’s new podcast, Bay Curious, gets to the bottom of the mysteries — both profound and peculiar — that give the Bay Area its unique identity. And we’ll do it with your help! You ask the questions. You decide what Bay Curious investigates. And you join us on the journey to find the answers.","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/Bay-Curious-Podcast-Tile-703x703-1.jpg","imageAlt":"\"KQED Bay Curious","officialWebsiteLink":"/news/series/baycurious","meta":{"site":"news","source":"kqed","order":"4"},"link":"/podcasts/baycurious","subscribe":{"apple":"https://podcasts.apple.com/us/podcast/bay-curious/id1172473406","npr":"https://www.npr.org/podcasts/500557090/bay-curious","rss":"https://ww2.kqed.org/news/category/bay-curious-podcast/feed/podcast","google":"https://podcasts.google.com/feed/aHR0cHM6Ly93dzIua3FlZC5vcmcvbmV3cy9jYXRlZ29yeS9iYXktY3VyaW91cy1wb2RjYXN0L2ZlZWQvcG9kY2FzdA","stitcher":"https://www.stitcher.com/podcast/kqed/bay-curious","spotify":"https://open.spotify.com/show/6O76IdmhixfijmhTZLIJ8k"}},"bbc-world-service":{"id":"bbc-world-service","title":"BBC World Service","info":"The day's top stories from BBC News compiled twice daily in the week, once at weekends.","airtime":"MON-FRI 9pm-10pm, TUE-FRI 1am-2am","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/BBC-World-Service-Podcast-Tile-360x360-1.jpg","officialWebsiteLink":"https://www.bbc.co.uk/sounds/play/live:bbc_world_service","meta":{"site":"news","source":"BBC World Service"},"link":"/radio/program/bbc-world-service","subscribe":{"apple":"https://itunes.apple.com/us/podcast/global-news-podcast/id135067274?mt=2","tuneIn":"https://tunein.com/radio/BBC-World-Service-p455581/","rss":"https://podcasts.files.bbci.co.uk/p02nq0gn.rss"}},"code-switch-life-kit":{"id":"code-switch-life-kit","title":"Code Switch / Life Kit","info":"\u003cem>Code Switch\u003c/em>, which listeners will hear in the first part of the hour, has fearless and much-needed conversations about race. Hosted by journalists of color, the show tackles the subject of race head-on, exploring how it impacts every part of society — from politics and pop culture to history, sports and more.\u003cbr />\u003cbr />\u003cem>Life Kit\u003c/em>, which will be in the second part of the hour, guides you through spaces and feelings no one prepares you for — from finances to mental health, from workplace microaggressions to imposter syndrome, from relationships to parenting. The show features experts with real world experience and shares their knowledge. Because everyone needs a little help being human.\u003cbr />\u003cbr />\u003ca href=\"https://www.npr.org/podcasts/510312/codeswitch\">\u003cem>Code Switch\u003c/em> offical site and podcast\u003c/a>\u003cbr />\u003ca href=\"https://www.npr.org/lifekit\">\u003cem>Life Kit\u003c/em> offical site and podcast\u003c/a>\u003cbr />","airtime":"SUN 9pm-10pm","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/Code-Switch-Life-Kit-Podcast-Tile-360x360-1.jpg","meta":{"site":"radio","source":"npr"},"link":"/radio/program/code-switch-life-kit","subscribe":{"apple":"https://podcasts.apple.com/podcast/1112190608?mt=2&at=11l79Y&ct=nprdirectory","google":"https://podcasts.google.com/feed/aHR0cHM6Ly93d3cubnByLm9yZy9yc3MvcG9kY2FzdC5waHA_aWQ9NTEwMzEy","spotify":"https://open.spotify.com/show/3bExJ9JQpkwNhoHvaIIuyV","rss":"https://feeds.npr.org/510312/podcast.xml"}},"commonwealth-club":{"id":"commonwealth-club","title":"Commonwealth Club of California Podcast","info":"The Commonwealth Club of California is the nation's oldest and largest public affairs forum. As a non-partisan forum, The Club brings to the public airwaves diverse viewpoints on important topics. The Club's weekly radio broadcast - the oldest in the U.S., dating back to 1924 - is carried across the nation on public radio stations and is now podcasting. Our website archive features audio of our recent programs, as well as selected speeches from our long and distinguished history. This podcast feed is usually updated twice a week and is always un-edited.","airtime":"THU 10pm, FRI 1am","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/Commonwealth-Club-Podcast-Tile-360x360-1.jpg","officialWebsiteLink":"https://www.commonwealthclub.org/podcasts","meta":{"site":"news","source":"Commonwealth Club of California"},"link":"/radio/program/commonwealth-club","subscribe":{"apple":"https://itunes.apple.com/us/podcast/commonwealth-club-of-california-podcast/id976334034?mt=2","google":"https://podcasts.google.com/feed/aHR0cDovL3d3dy5jb21tb253ZWFsdGhjbHViLm9yZy9hdWRpby9wb2RjYXN0L3dlZWtseS54bWw","tuneIn":"https://tunein.com/radio/Commonwealth-Club-of-California-p1060/"}},"considerthis":{"id":"considerthis","title":"Consider This","tagline":"Make sense of the day","info":"Make sense of the day. Every weekday afternoon, Consider This helps you consider the major stories of the day in less than 15 minutes, featuring the reporting and storytelling resources of NPR. Plus, KQED’s Bianca Taylor brings you the local KQED news you need to know.","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/Consider-This-Podcast-Tile-703x703-1.jpg","imageAlt":"Consider This from NPR and KQED","officialWebsiteLink":"/podcasts/considerthis","meta":{"site":"news","source":"kqed","order":"7"},"link":"/podcasts/considerthis","subscribe":{"apple":"https://podcasts.apple.com/podcast/id1503226625?mt=2&at=11l79Y&ct=nprdirectory","npr":"https://rpb3r.app.goo.gl/coronavirusdaily","google":"https://podcasts.google.com/feed/aHR0cHM6Ly9mZWVkcy5ucHIub3JnLzUxMDM1NS9wb2RjYXN0LnhtbA","spotify":"https://open.spotify.com/show/3Z6JdCS2d0eFEpXHKI6WqH"}},"forum":{"id":"forum","title":"Forum","tagline":"The conversation starts here","info":"KQED’s live call-in program discussing local, state, national and international issues, as well as in-depth interviews.","airtime":"MON-FRI 9am-11am, 10pm-11pm","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/Forum-Podcast-Tile-703x703-1.jpg","imageAlt":"KQED Forum with Mina Kim and Alexis Madrigal","officialWebsiteLink":"/forum","meta":{"site":"news","source":"kqed","order":"8"},"link":"/forum","subscribe":{"apple":"https://podcasts.apple.com/us/podcast/kqeds-forum/id73329719","google":"https://podcasts.google.com/feed/aHR0cHM6Ly9mZWVkcy5tZWdhcGhvbmUuZm0vS1FJTkM5NTU3MzgxNjMz","npr":"https://www.npr.org/podcasts/432307980/forum","stitcher":"https://www.stitcher.com/podcast/kqedfm-kqeds-forum-podcast","rss":"https://feeds.megaphone.fm/KQINC9557381633"}},"freakonomics-radio":{"id":"freakonomics-radio","title":"Freakonomics Radio","info":"Freakonomics Radio is a one-hour award-winning podcast and public-radio project hosted by Stephen Dubner, with co-author Steve Levitt as a regular guest. It is produced in partnership with WNYC.","imageSrc":"https://ww2.kqed.org/news/wp-content/uploads/sites/10/2018/05/freakonomicsRadio.png","officialWebsiteLink":"http://freakonomics.com/","airtime":"SUN 1am-2am, SAT 3pm-4pm","meta":{"site":"radio","source":"WNYC"},"link":"/radio/program/freakonomics-radio","subscribe":{"npr":"https://rpb3r.app.goo.gl/4s8b","apple":"https://itunes.apple.com/us/podcast/freakonomics-radio/id354668519","tuneIn":"https://tunein.com/podcasts/WNYC-Podcasts/Freakonomics-Radio-p272293/","rss":"https://feeds.feedburner.com/freakonomicsradio"}},"fresh-air":{"id":"fresh-air","title":"Fresh Air","info":"Hosted by Terry Gross, \u003cem>Fresh Air from WHYY\u003c/em> is the Peabody Award-winning weekday magazine of contemporary arts and issues. 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Hosted by Robin Young, Jeremy Hobson and Tonya Mosley.","airtime":"MON-THU 11am-12pm","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/Here-And-Now-Podcast-Tile-360x360-1.jpg","officialWebsiteLink":"http://www.wbur.org/hereandnow","meta":{"site":"news","source":"npr"},"link":"/radio/program/here-and-now","subsdcribe":{"apple":"https://itunes.apple.com/WebObjects/MZStore.woa/wa/viewPodcast?mt=2&id=426698661","tuneIn":"https://tunein.com/radio/Here--Now-p211/","rss":"https://feeds.npr.org/510051/podcast.xml"}},"how-i-built-this":{"id":"how-i-built-this","title":"How I Built This with Guy Raz","info":"Guy Raz dives into the stories behind some of the world's best known companies. How I Built This weaves a narrative journey about innovators, entrepreneurs and idealists—and the movements they built.","imageSrc":"https://ww2.kqed.org/news/wp-content/uploads/sites/10/2018/05/howIBuiltThis.png","officialWebsiteLink":"https://www.npr.org/podcasts/510313/how-i-built-this","airtime":"SUN 7:30pm-8pm","meta":{"site":"news","source":"npr"},"link":"/radio/program/how-i-built-this","subscribe":{"npr":"https://rpb3r.app.goo.gl/3zxy","apple":"https://itunes.apple.com/us/podcast/how-i-built-this-with-guy-raz/id1150510297?mt=2","tuneIn":"https://tunein.com/podcasts/Arts--Culture-Podcasts/How-I-Built-This-p910896/","rss":"https://feeds.npr.org/510313/podcast.xml"}},"inside-europe":{"id":"inside-europe","title":"Inside Europe","info":"Inside Europe, a one-hour weekly news magazine hosted by Helen Seeney and Keith Walker, explores the topical issues shaping the continent. No other part of the globe has experienced such dynamic political and social change in recent years.","airtime":"SAT 3am-4am","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/Inside-Europe-Podcast-Tile-300x300-1.jpg","meta":{"site":"news","source":"Deutsche Welle"},"link":"/radio/program/inside-europe","subscribe":{"apple":"https://itunes.apple.com/us/podcast/inside-europe/id80106806?mt=2","tuneIn":"https://tunein.com/radio/Inside-Europe-p731/","rss":"https://partner.dw.com/xml/podcast_inside-europe"}},"latino-usa":{"id":"latino-usa","title":"Latino USA","airtime":"MON 1am-2am, SUN 6pm-7pm","info":"Latino USA, the radio journal of news and culture, is the only national, English-language radio program produced from a Latino perspective.","imageSrc":"https://ww2.kqed.org/radio/wp-content/uploads/sites/50/2018/04/latinoUsa.jpg","officialWebsiteLink":"http://latinousa.org/","meta":{"site":"news","source":"npr"},"link":"/radio/program/latino-usa","subscribe":{"npr":"https://rpb3r.app.goo.gl/xtTd","apple":"https://itunes.apple.com/WebObjects/MZStore.woa/wa/viewPodcast?s=143441&mt=2&id=79681317&at=11l79Y&ct=nprdirectory","tuneIn":"https://tunein.com/radio/Latino-USA-p621/","rss":"https://feeds.npr.org/510016/podcast.xml"}},"live-from-here-highlights":{"id":"live-from-here-highlights","title":"Live from Here Highlights","info":"Chris Thile steps to the mic as the host of Live from Here (formerly A Prairie Home Companion), a live public radio variety show. Download Chris’s Song of the Week plus other highlights from the broadcast. Produced by American Public Media.","airtime":"SAT 6pm-8pm, SUN 11am-1pm","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/Live-From-Here-Podcast-Tile-360x360-1.jpg","officialWebsiteLink":"https://www.livefromhere.org/","meta":{"site":"arts","source":"american public media"},"link":"/radio/program/live-from-here-highlights","subscribe":{"apple":"https://itunes.apple.com/us/podcast/id1167173941","tuneIn":"https://tunein.com/radio/Live-from-Here-Highlights-p921744/","rss":"https://feeds.publicradio.org/public_feeds/a-prairie-home-companion-highlights/rss/rss"}},"marketplace":{"id":"marketplace","title":"Marketplace","info":"Our flagship program, helmed by Kai Ryssdal, examines what the day in money delivered, through stories, conversations, newsworthy numbers and more. Updated Monday through Friday at about 3:30 p.m. PT.","airtime":"MON-FRI 4pm-4:30pm, MON-WED 6:30pm-7pm","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/Marketplace-Podcast-Tile-360x360-1.jpg","officialWebsiteLink":"https://www.marketplace.org/","meta":{"site":"news","source":"American Public Media"},"link":"/radio/program/marketplace","subscribe":{"apple":"https://itunes.apple.com/WebObjects/MZStore.woa/wa/viewPodcast?s=143441&mt=2&id=201853034&at=11l79Y&ct=nprdirectory","tuneIn":"https://tunein.com/radio/APM-Marketplace-p88/","rss":"https://feeds.publicradio.org/public_feeds/marketplace-pm/rss/rss"}},"mindshift":{"id":"mindshift","title":"MindShift","tagline":"A podcast about the future of learning and how we raise our kids","info":"The MindShift podcast explores the innovations in education that are shaping how kids learn. Hosts Ki Sung and Katrina Schwartz introduce listeners to educators, researchers, parents and students who are developing effective ways to improve how kids learn. We cover topics like how fed-up administrators are developing surprising tactics to deal with classroom disruptions; how listening to podcasts are helping kids develop reading skills; the consequences of overparenting; and why interdisciplinary learning can engage students on all ends of the traditional achievement spectrum. This podcast is part of the MindShift education site, a division of KQED News. KQED is an NPR/PBS member station based in San Francisco. You can also visit the MindShift website for episodes and supplemental blog posts or tweet us \u003ca href=\"https://twitter.com/MindShiftKQED\">@MindShiftKQED\u003c/a> or visit us at \u003ca href=\"/mindshift\">MindShift.KQED.org\u003c/a>","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/Mindshift-Podcast-Tile-703x703-1.jpg","imageAlt":"KQED MindShift: How We Will Learn","officialWebsiteLink":"/mindshift/","meta":{"site":"news","source":"kqed","order":"2"},"link":"/podcasts/mindshift","subscribe":{"apple":"https://podcasts.apple.com/us/podcast/mindshift-podcast/id1078765985","google":"https://podcasts.google.com/feed/aHR0cHM6Ly9mZWVkcy5tZWdhcGhvbmUuZm0vS1FJTkM1NzY0NjAwNDI5","npr":"https://www.npr.org/podcasts/464615685/mind-shift-podcast","stitcher":"https://www.stitcher.com/podcast/kqed/stories-teachers-share","spotify":"https://open.spotify.com/show/0MxSpNYZKNprFLCl7eEtyx"}},"morning-edition":{"id":"morning-edition","title":"Morning Edition","info":"\u003cem>Morning Edition\u003c/em> takes listeners around the country and the world with multi-faceted stories and commentaries every weekday. 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